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Journal Articles

Integrative Transcriptome and Quantitative Proteome Analyses Identify METTL3 As a Key Regulator for Aberrant RNA Processing in Chronic Lymphocytic Leukemia

Yiming Wu, PhD, Meiling Jin, PhD, Kevyn Hart, BS, Aijun Liao, MD PhD, Stacey M. Fernandes, BS, Tinisha McDonald, BS, Lucy Brown, PhD, Daniel Roeth, PhD, Markus Kalkum, PhD, Raju Pillai, MD, Jianjun Chen, PhD, Jennifer R Brown, MD PhD, Steven T. Rosen, MD, Tanya Siddiqi, MD, Lili Wang, MDPhD

Blood (2020) 136 (Supplement 1): 12.

https://doi.org/10.1182/blood-2020-139841

Published: 2020

Journal Articles

Effective Novel Fto Inhibitors Show Potent Anti-Cancer Efficacy and Suppress Drug Resistance

Blood (2019) 134 (Supplement_1): 233.

https://doi.org/10.1182/blood-2019-124535

Published: 2019

Journal Articles

Ifitm3 Is Essential for PI(3,4,5)P3-Dependent B-Cell Activation and Leukemogenesis

Jaewoong Lee, PhD, Gang Xiao, PhD, Kadriye Nehir Nehir Cosgun, PhD, Huimin Geng, PhD, Ning Ma, PhD, Lai N Chan, PhD, Kohei Kume, PhD, Matthew Nix, PhD, Zhengshan Chen, MD PhD, Chun-Wei David Chen, PhD, Jianjun Chen, PhD, Vishal Khairnar, PhD, Arun P. Wiita, MD PhD, Andrei Thomas-Tikhonenko, PhD, Michael Farzan, MD PhD, Michael S. Diamond, PhD, Jae U Jung, PhD, Nagarajan Vaidehi, PhD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 2782.

https://doi.org/10.1182/blood-2019-127615

Published: 2019

Journal Articles

TET1 Modulates DNA Replication in Leukemia Cells Via a Catalytic-Independent Mechanism through Cooperating with KAT8

Hengyou Weng, PhD, Huilin Huang, PhD, He Huang, Zhaojin Yu, Paulina Siejka-Zielinska, Zhenhua Chen, PhD, Emily Prince, Chao Shen, PhD, Zejuan Li, MD, Chunxiao Song, Yingming Zhao, Jianjun Chen, PhD

Blood (2019) 134 (Supplement_1): 1249.

https://doi.org/10.1182/blood-2019-127321

Published: 2019

Journal Articles

Identification of ZNF217 As an Essential Oncogenic Gene in B-Cell Acute Lymphoblastic Leukemia By CRISPR/Cas9-Based Library Screening

Xi Qin, Rui Su, PhD, Lu Yang, PhD, Anthony K. N. Chan, PhD, Xiaolan Deng, Ying Qing, Lars Klemm, MS, Markus Müschen, MD PhD, Chun-Wei David Chen, PhD, Jianjun Chen, PhD

Blood (2019) 134 (Supplement_1): 1465.

https://doi.org/10.1182/blood-2019-129849

Published: 2019

Journal Articles

N 6 -Methyladenosine Modification Regulates Cell Metabolism in Acute Myeloid Leukemia

Hengyou Weng, PhD, Huilin Huang, PhD, Huizhe Wu, Mingli Sun, Savanna Stanford, Sean Robinson, zhen-Hua Chen, Xi Qin, Xiaolan Deng, Xi Jiang, PhD, Ying Qing, Chao Shen, PhD, Rui Su, PhD, Minjie Wei, Jianjun Chen, PhD

Blood (2018) 132 (Supplement 1): 880.

https://doi.org/10.1182/blood-2018-99-117455

Published: 2018

Journal Articles

Inhibition of PRMT1 Mediated FLT3 Arginine Methylation As a Potent Therapeutic Strategy for MLL-r ALL

Yinghui Zhu, PhD, Xin He, PhD, Haojie Dong, PhD, Jie Sun, PhD, Hanying Wang, PhD, Lei Zhang, PhD, Yunan Miao, PhD, Jian Jin, PhD, Yudao Shen, PhD, Jianjun Chen, PhD, Markus Muschen, MD, Chun-Wei Chen, PhD, Marina Y. Konopleva, MD PhD, Weili Sun, MD PhD, Bin Zhang, PhD, Ya-Huei Kuo, PhD, Nadia Carlesso, MD PhD, Guido Marcucci, Ling Li, PhD

Blood (2018) 132 (Supplement 1): 892.

https://doi.org/10.1182/blood-2018-99-115139

Published: 2018

Journal Articles

PRMT1 Mediated FLT3 Methylation As a Therapeutic Vulnerability in FLT3-ITD + AML

Blood (2018) 132 (Supplement 1): 760.

https://doi.org/10.1182/blood-2018-99-112766

Published: 2018

Journal Articles

ALKBH5 Functions As an Oncogene in Acute Myeloid Leukemia

Chao Shen, PhD, Yue Sheng, PhD, Rui Su, PhD, Xiaolan Deng, Sean Robinson, Zhe Yin, MD, Lei Dong, PhD, Huilin Huang, PhD, Hengyou Weng, PhD, Chenying Li, MD, Zhijian Qian, Xi Jiang, PhD, Jianjun Chen, PhD

Blood (2018) 132 (Supplement 1): 3910.

https://doi.org/10.1182/blood-2018-99-118988

Published: 2018

Journal Articles

The Oncogenic Role of N 6 -Methyladenosine Reader Protein IGF2BP3 in Acute Myeloid Leukemia

Huilin Huang, PhD, Hengyou Weng, PhD, Mingli Sun, Huizhe Wu, Zhenhua Chen, PhD, Savanna Stanford, Xiaolan Deng, Rui Su, PhD, Minjie Wei, Jianjun Chen, PhD

Blood (2018) 132 (Supplement 1): 1334.

https://doi.org/10.1182/blood-2018-99-117535

Published: 2018

Journal Articles

Downregulation of Mir-142 Promotes Leukemia Growth in Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL): A Possible Novel Therapeutic Target?

Blood (2018) 132 (Supplement 1): 1338.

https://doi.org/10.1182/blood-2018-99-119599

Published: 2018

Journal Articles

Targeted Inhibition of STAT/TET1 Axis As a Potent Therapeutic Strategy for Acute Myeloid Leukemia

Blood (2017) 130 (Supplement 1): 857.

https://doi.org/10.1182/blood.V130.Suppl_1.857.857

Published: 2017

Journal Articles

Fto Plays an Oncogenic Role in Acute Myeloid Leukemia As a N 6 -Methyladenosine RNA Demethylase

Blood (2016) 128 (22): 2706.

https://doi.org/10.1182/blood.V128.22.2706.2706

Published: 2016

Journal Articles

TET1 Regulates DNA Replication through Targeting of Minichromosome Maintenance Genes

Blood (2016) 128 (22): 2687.

https://doi.org/10.1182/blood.V128.22.2687.2687

Published: 2016

Journal Articles

Alox5 Functions As Both Tumor Suppressor and Drug Sensitizer in AML

Xi Jiang, PhD, Yungui Wang, PhD, Chao Hu, PhD, Jennifer Strong, Lei Dong, PhD, Rui Su, PhD, Hengyou Weng, PhD, Huilin Huang, PhD, Chenying Li, Jie Jin, MD PhD, Jianjun Chen, PhD

Blood (2016) 128 (22): 2851.

https://doi.org/10.1182/blood.V128.22.2851.2851

Published: 2016

Journal Articles

The N 6 -Adenine Methyltransferase METTL14 Plays an Oncogenic Role in Acute Myeloid Leukemia

Huilin Huang, PhD, Hengyou Weng, PhD, Xi Qin, Boxuan Simen Zhao, PhD, Lou Dore, Jennifer Strong, Rui Su, PhD, Kyle Ferchen, Chenying Li, Lei Dong, Xi Jiang, PhD, Chuan He, PhD, Jianjun Chen, PhD

Blood (2016) 128 (22): 1536.

https://doi.org/10.1182/blood.V128.22.1536.1536

Published: 2016

Journal Articles

Mircrorna-550 Functions As a Critical Tumor Suppressor in Acute Myeloid Leukemia

Chao Hu, Xi Jiang, PhD, Bryan Ulrich, Yungui Wang, PhD, Rui Su, PhD, Hengyou Weng, PhD, Huilin Huang, PhD, Jennifer Strong, Ping Chen, Shenglai Li, Jianjun Chen, PhD, Jie Jin, MD PhD

Blood (2015) 126 (23): 1240.

https://doi.org/10.1182/blood.V126.23.1240.1240

Published: 2015

Journal Articles

Overexpression and Knockout of Mir-126 Both Promote Leukemogenesis through Targeting Distinct Gene Signaling

Blood (2015) 126 (23): 3667.

https://doi.org/10.1182/blood.V126.23.3667.3667

Published: 2015

Journal Articles

Uncover TET1 Targets in MLL -Rearranged Leukemia

Hengyou Weng, PhD, Huilin Huang, PhD, He Huang, PhD, Okwang Kwon, Ping Chen, Xi Jiang, PhD, Chao Hu, Hao Huang, PhD, Yungui Wang, PhD, Xi Qin, Stephen Arnovitz, Shenglai Li, Jennifer Strong, Rui Su, PhD, Mary Beth Neilly, Zejuan Li, MD PhD, Yingming Zhao, Jianjun Chen, PhD

Blood (2015) 126 (23): 3632.

https://doi.org/10.1182/blood.V126.23.3632.3632

Published: 2015

Journal Articles

Targeted Treatment of FLT3 -Overexpressing Acute Myeloid Leukemia with MiR-150 Nanoparticles Guided By Conjugated FLT3 Ligand Peptides

Blood (2015) 126 (23): 3784.

https://doi.org/10.1182/blood.V126.23.3784.3784

Published: 2015

NARROW

Integrative Transcriptome and Quantitative Proteome Analyses Identify METTL3 As a Key Regulator for Aberrant RNA Processing in Chronic Lymphocytic Leukemia

Effective Novel Fto Inhibitors Show Potent Anti-Cancer Efficacy and Suppress Drug Resistance

Ifitm3 Is Essential for PI(3,4,5)P3-Dependent B-Cell Activation and Leukemogenesis

TET1 Modulates DNA Replication in Leukemia Cells Via a Catalytic-Independent Mechanism through Cooperating with KAT8

Identification of ZNF217 As an Essential Oncogenic Gene in B-Cell Acute Lymphoblastic Leukemia By CRISPR/Cas9-Based Library Screening

N 6 -Methyladenosine Modification Regulates Cell Metabolism in Acute Myeloid Leukemia

Inhibition of PRMT1 Mediated FLT3 Arginine Methylation As a Potent Therapeutic Strategy for MLL-r ALL

PRMT1 Mediated FLT3 Methylation As a Therapeutic Vulnerability in FLT3-ITD + AML

ALKBH5 Functions As an Oncogene in Acute Myeloid Leukemia

The Oncogenic Role of N 6 -Methyladenosine Reader Protein IGF2BP3 in Acute Myeloid Leukemia

Downregulation of Mir-142 Promotes Leukemia Growth in Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL): A Possible Novel Therapeutic Target?

Targeted Inhibition of STAT/TET1 Axis As a Potent Therapeutic Strategy for Acute Myeloid Leukemia

Fto Plays an Oncogenic Role in Acute Myeloid Leukemia As a N 6 -Methyladenosine RNA Demethylase

TET1 Regulates DNA Replication through Targeting of Minichromosome Maintenance Genes

Alox5 Functions As Both Tumor Suppressor and Drug Sensitizer in AML

The N 6 -Adenine Methyltransferase METTL14 Plays an Oncogenic Role in Acute Myeloid Leukemia

Mircrorna-550 Functions As a Critical Tumor Suppressor in Acute Myeloid Leukemia

Overexpression and Knockout of Mir-126 Both Promote Leukemogenesis through Targeting Distinct Gene Signaling

Uncover TET1 Targets in MLL -Rearranged Leukemia

Targeted Treatment of FLT3 -Overexpressing Acute Myeloid Leukemia with MiR-150 Nanoparticles Guided By Conjugated FLT3 Ligand Peptides

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American Society of Hematology

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American Society of Hematology

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