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John D Roback
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Journal Articles

Antibody-mediated antigen loss switches augmented immunity to antibody-mediated immunosuppression

Ryan P. Jajosky, Kashyap R. Patel, Jerry William L. Allen, Patricia E. Zerra, Satheesh Chonat, Diyoly Ayona, Cheryl L. Maier, Dominique Morais, Shang-Chuen Wu, C. John Luckey, Stephanie C. Eisenbarth, John D. Roback, Ross M. Fasano, Cassandra D. Josephson, John P. Manis, Li Chai, Jeanne E. Hendrickson, Krystalyn E. Hudson, Connie M. Arthur, Sean R. Stowell
Journal: Blood
Blood (2023) 142 (12): 1082–1098.
https://doi.org/10.1182/blood.2022018591
Published: 2023
Includes: Supplemental data
Journal Articles

Blood group A enhances SARS-CoV-2 infection

Brief Report
Shang-Chuen Wu, Connie M. Arthur, Hau-Ming Jan, Wilfredo F. Garcia-Beltran, Kashyap R. Patel, Matthew F. Rathgeber, Hans P. Verkerke, Narayanaiah Cheedarla, Ryan Philip Jajosky, Anu Paul, Andrew S. Neish, John D. Roback, Cassandra D. Josephson, Duane R. Wesemann, Daniel Kalman, Seth Rakoff-Nahoum, Richard D. Cummings, Sean R. Stowell
Journal: Blood
Blood (2023) 142 (8): 742–747.
https://doi.org/10.1182/blood.2022018903
Published: 2023
Includes: Supplemental data
Journal Articles

PI3Kδ/γ Inhibitor Duvelisib Modulates Inflammatory Profile in Severe COVID-19 Patients: Results from a Randomized Placebo-Controlled Phase 2 Study

Hanwen Zhang, Shuhua Wang, Manali Rupji, Chenxi Wu, Sanjay Chandrasekaran, Christopher R. Funk, Patrick J. King, Saketh Kollipara, Ishani Rao, Esohe Ayanru, Julia Duffy, Roberta Kaplow, Aseala Abousaud, Aneesh Mehta, John D. Roback, Daniel Kalman, G. Marshall Lyon, III, Mark Caridi-Scheible, Gregory Bisson, Yuan Liu, Silvia Coma, Jonathan A. Pachter, Cynthia R. Giver, Edmund K. Waller
Journal: Blood
Blood (2022) 140 (Supplement 1): 11187–11189.
https://doi.org/10.1182/blood-2022-165567
Published: 2022
Journal Articles

Molecular Determinants of Human Red Blood Cell Survival in Murine Circulation

Jiusheng Deng, Moira M. Lancelot, Ryan Jajosky, Marianne M Yee, Natia Saakadze, Sean R Stowell, John D. Roback
Journal: Blood
Blood (2022) 140 (Supplement 1): 5708.
https://doi.org/10.1182/blood-2022-155929
Published: 2022
Journal Articles

Blood Group A Enhances SARS-CoV-2 Infection

Shang-Chuen Wu, Connie M. Arthur, Hau-Ming Jan, Wilfredo F Garcia-Beltran, Kashyap R. Patel, Matthew F. Rathgeber, Hans Verkerke, Narayanaiah Cheedarla, Ryan Philip Jajosky, Anu Paul, Andrew S. Neish, John D. Roback, Cassandra D. Josephson, Duane R. Wesemann, Daniel Kalman, Seth Rakoff-Nahoum, Richard D. Cummings, Sean R. Stowell
Journal: Blood
Blood (2022) 140 (Supplement 1): 79–80.
https://doi.org/10.1182/blood-2022-170083
Published: 2022
Journal Articles

Antibody-Mediated Antigen Loss Can Switch an Augmented Immune Response to Antibody-Mediated Immunosuppression

Ryan Philip Jajosky, Jerry W. Allen, Patricia E Zerra, Cheryl L Maier, Satheesh Chonat, Chance John Luckey, John D. Roback, Ross M. Fasano, Cassandra D. Josephson, John P Manis, Li Chai, Jeanne E. Hendrickson, Krystalyn E Hudson, Connie M. Arthur, Sean R. Stowell
Journal: Blood
Blood (2022) 140 (Supplement 1): 73–74.
https://doi.org/10.1182/blood-2022-170081
Published: 2022
Journal Articles

Donor plasmacytoid dendritic cells limit graft-versus-host disease through vasoactive intestinal polypeptide expression

Jingru Zhu, Yitong Wang, Jingxia Li, Pankoj Kumar Das, Hanwen Zhang, Tenzin Passang, Jian Ming Li, Tamas Nagy, Khanjan Gandhi, Sruthi Ravindranathan, Cynthia R. Giver, Mojibade Hassan, Yiwen Li, Alina Ulezko Antonova, Shuhua Wang, John D. Roback, Edmund K. Waller
Journal: Blood
Blood (2022) 140 (12): 1431–1447.
https://doi.org/10.1182/blood.2021012561
Published: 2022
Includes: Supplemental data
Journal Articles

Donor Plasmacytoid Dendritic Cells Regulate GvHD in a VIP Dependent Manner in Allogeneic BMT Recipients

Jingru Zhu, Pankoj Kumar Das, Yitong Wang, Jingxia Li, Tamas Nagy, Khajan Ghandhi, Sruthi Ravindranathan, Cynthia R. Giver, Jian-Ming Li, Yiwen Li, Alina Ulezko Antonova, John D Roback, Shuhua Wang, Edmund K. Waller
Journal: Blood
Blood (2021) 138 (Supplement 1): 1687.
https://doi.org/10.1182/blood-2021-152945
Published: 2021
Journal Articles

Marginal zone B cells mediate a CD4 T-cell–dependent extrafollicular antibody response following RBC transfusion in mice

Patricia E. Zerra, Seema R. Patel, Ryan Philip Jajosky, Connie M. Arthur, James W. McCoy, Jerry William Lynn Allen, Satheesh Chonat, Ross M. Fasano, John D. Roback, Cassandra D. Josephson, Jeanne E. Hendrickson, Sean R. Stowell
Journal: Blood
Blood (2021) 138 (8): 706–721.
https://doi.org/10.1182/blood.2020009376
Published: 2021
Includes: Supplemental data
Journal Articles

Efficient Enucleation and In Vivo Circulation of Differentiated Human Erythroblasts Derived from Peripheral Blood Mononuclear Cells after Extensive Expansion

Senquan Liu, PhD, Mengyao Wu, PhD, Yongxing Gao, MS, Jiusheng Deng, PhD, John D Roback, MD PhD, Tong Chen, MD PhD, Linzhao Cheng, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 23–24.
https://doi.org/10.1182/blood-2020-142226
Published: 2020
Journal Articles

Characteristics of in Vitro Differentiated Erythrocytes Derived from Human Bmi-1 Extensively Expanded Erythroblasts (E3)

Moira M. Lancelot, MD, Natia Saakadze, MSc, Jiusheng Deng, PhD, Sean R. Stowell, MD PhD, Ryan Jajosky, MD, Linzhao Cheng, PhD, Senquan Liu, John D Roback, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30.
https://doi.org/10.1182/blood-2020-142726
Published: 2020
Journal Articles

Effective Erythropoiesis from Human iPSC-Derived RBC in Immunodeficient Mice

Jiusheng Deng, PhD, Moira M. Lancelot, MD, Ryan Jajosky, MD, Kristin Deeb, PhD, Natia Saakadze, MSc, Yongixng Gao, MD, Senquan Liu, PhD, Sean R. Stowell, MD PhD, Linzhao Cheng, PhD, John D Roback, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42.
https://doi.org/10.1182/blood-2020-138606
Published: 2020
Journal Articles

Integrated Microfluidic Automated Particle Tracking Enables High-Throughput Cell Deformability Cytometry for Red Cell Disorders

Christina Caruso, MD, Puneeth Guruprasad, Robert G Mannino, PhD, Hanqing Zhang, PhD, Cassandra D Josephson, MD, John D Roback, MD PhD, Wilbur A Lam, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1033.
https://doi.org/10.1182/blood-2018-99-118830
Published: 2018
Journal Articles

Daratumumab (anti-CD38) induces loss of CD38 on red blood cells

Harold C. Sullivan, Christian Gerner-Smidt, Ajay K. Nooka, Connie M. Arthur, Louisa Thompson, Amanda Mener, Seema R. Patel, Marianne Yee, Ross M. Fasano, Cassandra D. Josephson, Richard M. Kaufman, John D. Roback, Sagar Lonial, Sean R. Stowell
Journal: Blood
Blood (2017) 129 (22): 3033–3037.
https://doi.org/10.1182/blood-2016-11-749432
Published: 2017
Includes: Supplemental data
Journal Articles

IFN-γ and indoleamine 2,3-dioxygenase signaling between donor dendritic cells and T cells regulates graft versus host and graft versus leukemia activity

Ying Lu, Cynthia R. Giver, Akshay Sharma, Jian Ming Li, Katarzyna A. Darlak, Lauren M. Owens, John D. Roback, Jacques Galipeau, Edmund K. Waller
Journal: Blood
Blood (2012) 119 (4): 1075–1085.
https://doi.org/10.1182/blood-2010-12-322891
Published: 2012
Journal Articles

Prophylactic Use of Flagellin: A Novel Method to Boost Immune Reconstitution in Allogeneic HSCT Recipients with Limited GvHD.

Mohammad S Hossain, PhD, Andrew T Gewirtz, Ph.D., John D Roback, MD., Ph.D., Edmund K. Waller, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3561.
https://doi.org/10.1182/blood.V114.22.3561.3561
Published: 2009
Journal Articles

Flagellin, a TLR5 Agonist, Down-Regulate CD62L on Donor T Cells and Limit GvHD in Allogeneic Hematopoietic Stem Cell Transplantation

Mohammad Hossain, PhD, Andrew T Gewirtz, Ph.D., John D Roback, MD., Ph.D., Edmund K. Waller, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3521.
https://doi.org/10.1182/blood.V112.11.3521.3521
Published: 2008
Journal Articles

An Intact Spleen Is Required for Alloimmunization to Transfused Red Blood Cells Due to Intrasplenic Activation of CD4+ T Cells.

Jeanne E. Hendrickson, MD, John D. Roback, MD, PhD, Christopher D. Hillyer, MD, James C. Zimring, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 453.
https://doi.org/10.1182/blood.V110.11.453.453
Published: 2007
Journal Articles

Inactivation of Infectious CMV in Platelet Products: Comparison of INTERCEPT Blood System™ and Leukofiltration.

John D. Roback, MD, PhD, Herve Isola, Lily Lin, PhD, Jean-Pierre Cazenave, MD
Journal: Blood
Blood (2007) 110 (11): 2886.
https://doi.org/10.1182/blood.V110.11.2886.2886
Published: 2007
Journal Articles

Inflammation enhances consumption and presentation of transfused RBC antigens by dendritic cells

Jeanne E. Hendrickson, Traci E. Chadwick, John D. Roback, Christopher D. Hillyer, James C. Zimring
Journal: Blood
Blood (2007) 110 (7): 2736–2743.
https://doi.org/10.1182/blood-2007-03-083105
Published: 2007