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Journal Articles

Hyperactive Non-Canonical TGF-β Pathway Signaling in Fanconi Anemia Bone Marrow Stromal Cells Contributes to Growth Suppression

Kevin O'Connor, Sofia Vidal-Cardenas, PhD, Haojian Zhang, PhD, Alfredo Rodriguez, Lisa Moreau, Chunyu Yang, Michael W Epperly, PhD, Markus Grompe, MD, Akiko Shimamura, MD PhD, Joel S. Greenberger, MD, Kalindi Parmar, PhD, Alan D D'Andrea, MD

Blood (2016) 128 (22): 1039.

https://doi.org/10.1182/blood.V128.22.1039.1039

Published: 2016

Journal Articles

TGF-β Pathway Inhibition Rescues the Function of Hematopoietic Stem and Progenitor Cells Derived from Patients with Fanconi Anemia

Haojian Zhang, PhD, David Kozono, MD PhD, Kevin O'Connor, Alix Rousseau, Lisa Moreau, Emily Gaudiano, BS, Joel S Greenberger, MD, Grover C. Bagby, Jr., MD MACP, Jean Soulier, MD PhD, Markus Grompe, MD, Kalindi Parmar, PhD, Alan D D'Andrea, MD

Blood (2015) 126 (23): 297.

https://doi.org/10.1182/blood.V126.23.297.297

Published: 2015

Journal Articles

Bone Marrow Failure in Fanconi Anemia from Hyperactive TGF-β Signaling

Haojian Zhang, PhD, David Kozono, MD PhD, Kevin O'Connor, BA, Sofia Vidal-Cardenas, PhD, Abigail Hamilton, BA, Emily Gaudiano, BS, Joel S. Greenberger, MD, Markus Grompe, MD, Kalindi Parmar, PhD, Alan D. D'Andrea, MD

Blood (2014) 124 (21): 356.

https://doi.org/10.1182/blood.V124.21.356.356

Published: 2014

Journal Articles

Intraoral Mitochondrial-Targeted GS Nitroxide JP4-039 Ameliorates Radiation-Induced Mucositis in Orthotopic Tumor-Bearing Fanconi Anemia (FA) ( Fancd2-/- ) Mice.

Ashwin Shinde, Byung Han Rhieu, Hebist Berhane, Eva C. Guinan, MD, Kalindi Parmar, PhD, Hong Wang, PhD, Darcy Franicola, Xichen Zhang, Song Li, Tracy M. Dixon, Joel S. Greenberger, MD

Blood (2014) 124 (21): 5961.

https://doi.org/10.1182/blood.V124.21.5961.5961

Published: 2014

Journal Articles

Small Molecule Inhibitors of USP1 Target ID1 Degradation in Leukemic Cells and Cause Cytotoxicity

Helena Mistry, Ph.D., Grace Hsieh, M.D., Sara Buhrlage, Ph.D, Min Huang, Ph.D., Eunmi Park, Ph.D., Gregory Cuny, Ph.D., Ilene Galinsky, ANP, Richard M. Stone, MD, Nathanael S Gray, PhD, Kalindi Parmar, PhD, Alan D. D'Andrea, MD

Blood (2013) 122 (21): 2906.

https://doi.org/10.1182/blood.V122.21.2906.2906

Published: 2013

Journal Articles

Characterization Of Full-Length, Recombinant Amsh, USP9x, and USP1: Clinically-Relevant Deubiquitinases Involved In Hematological Malignancies

Nate Russell, Trevor Taylor, Kalindi Parmar, PhD, Alan D. D'Andrea, MD, Bradley B Brasher, Ph.D., Francesco D Melandri

Blood (2013) 122 (21): 4224.

https://doi.org/10.1182/blood.V122.21.4224.4224

Published: 2013

Journal Articles

Overcoming reprogramming resistance of Fanconi anemia cells

Lars U. W. Müller, Michael D. Milsom, Chad E. Harris, Rutesh Vyas, Kristina M. Brumme, Kalindi Parmar, Lisa A. Moreau, Axel Schambach, In-Hyun Park, Wendy B. London, Kelly Strait, Thorsten Schlaeger, Alexander L. DeVine, Elke Grassman, Alan D'Andrea, George Q. Daley, David A. Williams

Blood (2012) 119 (23): 5449–5457.

https://doi.org/10.1182/blood-2012-02-408674

Published: 2012

Includes: Supplemental data

Journal Articles

Gene-Correction Rescues Reprogramming of Fanconi Anemia Fibroblasts and Enables Hematopoietic Differentiation of FA Induced Pluripotent Stem Cells in Vitro and In Vivo

Lars Mueller, MD, Michael D. Milsom, PhD, Chad Harris, Rutesh Vyas, Kristina Brumme, Kalindi Parmar, PhD, Axel Schambach, MD PhD, Elke Grassman, Ph.D., In-Hyun Park, PhD, London Wendy, PhD, Kelly Strait, Thorsten Schlaeger, Ph.D, Alexander L. Devine, Alan D. D'Andrea, MD, George Q. Daley, MD, PhD, David A. Williams, MD

Blood (2011) 118 (21): 672.

https://doi.org/10.1182/blood.V118.21.672.672

Published: 2011

Journal Articles

Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization

Shuxian Jiang, Meritxell Alberich-Jorda, Radoslaw Zagozdzon, Kalindi Parmar, Yigong Fu, Peter Mauch, Naheed Banu, Alexandros Makriyannis, Daniel G. Tenen, Shalom Avraham, Jerome E. Groopman, Hava Karsenty Avraham

Blood (2011) 117 (3): 827–838.

https://doi.org/10.1182/blood-2010-01-265082

Published: 2011

Includes: Supplemental data

Journal Articles

Cytokinesis Failure In Fanconi Anemia Pathway Deficient Hematopoietic Cells

Kalindi Parmar, Ph.D, Patrizia Vinciguerra, Ph.D., Susana Godinho, Ph.D., Abigail Hamilton, BA, David Pellman, MD, Alan D. D'Andrea, MD

Blood (2010) 116 (21): 878.

https://doi.org/10.1182/blood.V116.21.878.878

Published: 2010

Journal Articles

Mechanisms of Resistance to Reprogramming of Cells Defective In the Fanconi Anemia DNA Repair Pathway

Lars Mueller, MD, Michael D. Milsom, PhD, Kristina Brumme, Chad Harris, Kalindi Parmar, PhD, Kaya Zhu, London Wendy, PhD, Kelly Strait, Alan D. D'Andrea, MD, George Q. Daley, MD, PhD, David A. Williams, MD

Blood (2010) 116 (21): 196.

https://doi.org/10.1182/blood.V116.21.196.196

Published: 2010

Journal Articles

Cytokinesis Failure in Fanconi Anemia Pathway Deficient Murine Hematopoietic Stem Cells.

Patrizia Vinciguerra, PhD, Susana Godinho, PhD, Kalindi Parmar, PhD, David Pellman, MD, Alan D'Andrea, MD

Blood (2009) 114 (22): 495.

https://doi.org/10.1182/blood.V114.22.495.495

Published: 2009

Journal Articles

Hematopoietic Stem Cell Defects in Novel Fanconi Anemia Mouse Models

Kalindi Parmar, PhD, Jung Min Kim, PhD, Akiko Shimamura, MD, PhD, Anna Stuckert, Mary K DeLoach, Kaya Zhu, Peter M. Mauch, MD, Jeffery Kutok, MD, PhD, Jon Aster, MD, PhD, Koichi Akashi, MD, PhD, D. Gary Gilliland, MD, PhD, Alan D. D’Andrea, MD

Blood (2008) 112 (11): 440.

https://doi.org/10.1182/blood.V112.11.440.440

Published: 2008

Journal Articles

Defining the Bone Marrow Stem Cell Niche According to a Hoechst Dye Diffusion Gradient and Hypoxia.

Julian D. Down, Ph.D., Kalindi Parmar, Ph.D., James Clyne, B.S., Peter M. Mauch, M.D., Robert Sackstein, M.D., Ph.D.

Blood (2004) 104 (11): 666.

https://doi.org/10.1182/blood.V104.11.666.666

Published: 2004

NARROW

Hyperactive Non-Canonical TGF-β Pathway Signaling in Fanconi Anemia Bone Marrow Stromal Cells Contributes to Growth Suppression

TGF-β Pathway Inhibition Rescues the Function of Hematopoietic Stem and Progenitor Cells Derived from Patients with Fanconi Anemia

Bone Marrow Failure in Fanconi Anemia from Hyperactive TGF-β Signaling

Intraoral Mitochondrial-Targeted GS Nitroxide JP4-039 Ameliorates Radiation-Induced Mucositis in Orthotopic Tumor-Bearing Fanconi Anemia (FA) ( Fancd2-/- ) Mice.

Small Molecule Inhibitors of USP1 Target ID1 Degradation in Leukemic Cells and Cause Cytotoxicity

Characterization Of Full-Length, Recombinant Amsh, USP9x, and USP1: Clinically-Relevant Deubiquitinases Involved In Hematological Malignancies

Overcoming reprogramming resistance of Fanconi anemia cells

Gene-Correction Rescues Reprogramming of Fanconi Anemia Fibroblasts and Enables Hematopoietic Differentiation of FA Induced Pluripotent Stem Cells in Vitro and In Vivo

Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization

Cytokinesis Failure In Fanconi Anemia Pathway Deficient Hematopoietic Cells

Mechanisms of Resistance to Reprogramming of Cells Defective In the Fanconi Anemia DNA Repair Pathway

Cytokinesis Failure in Fanconi Anemia Pathway Deficient Murine Hematopoietic Stem Cells.

Hematopoietic Stem Cell Defects in Novel Fanconi Anemia Mouse Models

Defining the Bone Marrow Stem Cell Niche According to a Hoechst Dye Diffusion Gradient and Hypoxia.

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American Society of Hematology

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American Society of Hematology

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