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Journal Articles

Somatic TP53 mutations are preleukemic events in acute lymphoblastic leukemia

Guranda Chitadze, Anna Stengel, Cathrin John-Klaua, Julien Bruckmüller, Heiko Trautmann, Michaela Kotrova, Franziska Darzentas, Miriam Kelm, Karol Pal, Nikos Darzentas, Lorenz Bastian, Britta Kehden, Wiebke Wessels, Aeint-Steffen Ströh, Hans-Heinrich Oberg, Philipp M. Altrock, Constance Baer, Manja Meggendorfer, Nicola Gökbuget, Claudia D. Baldus, Claudia Haferlach, Monika Brüggemann
Journal: Blood
Blood (2023) 141 (13): 1640–1644.
https://doi.org/10.1182/blood.2022017249
Published: 2023
Includes: Supplemental data
Journal Articles

Genotyping and Minimal Residual Disease (MRD) Assessment in cfDNA By the Euroclonality-NGS DNA Capture (EC-NDC) Panel in Mantle Cell Lymphoma (MCL)

Mouhamad Khouja, Elisa Genuardi, Simone Ferrero, Beatrice Alessandria, Onno Verhagen, Christa Homburg, Vincent H.J. van der Velden, Paula Gameiro, Ramón García-Sanz, Alejandro Medina, Eva Fronkova, Monika Brüggemann, Martin Dreyling, Eva Hoster, Anton Langerak, Nikos Darzentas, Karol Pal, Peter James Stewart, David Gonzalez, Christiane Pott
Journal: Blood
Blood (2022) 140 (Supplement 1): 3518–3520.
https://doi.org/10.1182/blood-2022-166043
Published: 2022
Journal Articles

Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options

Clinical Trials & Observations
Jitka Malcikova, Sarka Pavlova, Barbara Kunt Vonkova, Lenka Radova, Karla Plevova, Jana Kotaskova, Karol Pal, Barbara Dvorackova, Marcela Zenatova, Jakub Hynst, Eva Ondrouskova, Anna Panovska, Yvona Brychtova, Kristyna Zavacka, Boris Tichy, Nikola Tom, Jiri Mayer, Michael Doubek, Sarka Pospisilova
Journal: Blood
Blood (2021) 138 (25): 2670–2685.
https://doi.org/10.1182/blood.2020009530
Published: 2021
Includes: Supplemental data
Journal Articles

Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1

Sarah Reinke, Paul J. Bröckelmann, Ingram Iaccarino, Maria Garcia-Marquez, Sven Borchmann, Franziska Jochims, Michaela Kotrova, Karol Pal, Monika Brüggemann, Elena Hartmann, Stephanie Sasse, Carsten Kobe, Stephan Mathas, Martin Soekler, Ulrich Keller, Matthias Bormann, Andreas Zimmermann, Julia Richter, Michael Fuchs, Bastian von Tresckow, Peter Borchmann, Hans Schlößer, Michael von Bergwelt-Baildon, Andreas Rosenwald, Andreas Engert, Wolfram Klapper
Journal: Blood
Blood (2020) 136 (25): 2851–2863.
https://doi.org/10.1182/blood.2020008553
Published: 2020
Includes: Supplemental data
Journal Articles

Targeted Next Generation Sequencing Improves Diagnosis in Unclassifiable Leukemic Indolent B-Cell Non-Hodgkin Lymphoma and Identifies a Subset with Recurrent MYD88 Mutations in a Prospective Multicentre Study

Matthew J Cross, MBBS, BSc, Grzegorz Pietka, PhD, Sarah Dunne, Leonora Conneely, Michael Hubank, PhD, Corinne De Lord, MD FRCPath, Michelle Furtado, MD FRCPath, PhD, Pawel Kaczmarek, MD PhD, Dima El-Sharkawi, Claire E. Dearden, MD FRCP, FRCPath, Kabir Mohammed, Alan Stewart Dunlop, MSc, BS, Ricardo Morilla, Karol Pal, PhD, Nikos Darzentas, PhD, David Gonzalez, PhD, Dorte Wren, PhDFRCPath, Sunil Iyengar, MD FRCPath, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-141542
Published: 2020
Journal Articles

Euroclonality-NGS DNA Capture Panel for Integrated Analysis of IG/TR Rearrangements, Translocations, Copy Number and Sequence Variation in Lymphoproliferative Disorders

Peter Stewart, PhD, Jana Gazdova, MSc, Nikos Darzentas, PhD, Dorte Wren, PhDFRCPath, Paula Proszek, Grazia Fazio, Simona Songia, Miguel Alcoceba, Maria Eugenia Sarasquete, PhD, Patrick Villarese, PhD, Michèle Y van der Klift, Kim Heezen, Neil McCafferty, MSc, Karol Pal, MSc, Mark Catherwood, PhD, Chang Sik Kim, PhD, Shambhavi Srivastava, PhD, Elizabeth Hodges, PhD, Kostas Stamatopoulos, Wolfram Klapper, Simone Ferrero, MD, Michiel van den Brand, MD, Giovanni Cazzaniga, PhD, Frederic Davi, MD PhD, Ramon Garcia-Sanz, MD PhD, Patricia Groenen, Elizabeth Macintyre, PhDMD, Monika Brüggemann, Christiane Pott, MD PhD, Elisa Genuardi, Anton W Langerak, PhD, David Gonzalez, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 888.
https://doi.org/10.1182/blood-2019-127822
Published: 2019
Journal Articles

Prognostic Impact of NOTCH1 Hotspot Mutation in TP53 -Mutated Patients with Chronic Lymphocytic Leukemia

Barbara Kantorova, M.S., Jitka Malcikova, PhD, Veronika Navrkalova, M.S., PhD, Jana Smardova, Prof., MD PhD, Kamila Brazdilova, M.S., Karla Plevova, M.S., PhD, Eva Diviskova, M.S., Marek Borsky, M.S., Sarka Pavlova, M.S., PhD, Nikola Tom, M.S., Karol Pal, M.S., Martin Trbusek, Dr., PhD, Alexandra Oltova, Dr., Yvona Brychtova, MD PhD, Michael Doubek, Prof., MD PhD, Jiri Mayer, Prof., MD PhD, Sarka Pospisilova, Prof., Dr., PhD
Journal: Blood
Blood (2014) 124 (21): 3283.
https://doi.org/10.1182/blood.V124.21.3283.3283
Published: 2014
Journal Articles

Mutational Analysis of TP53 Gene in Chronic Lymphocytic Leukemia: Comparison of Different Methodological Approaches

Barbara Kantorova, MSc., Jitka Malcikova, Dr., PhD., Jana Kminkova, PharmD., Veronika Navrkalova, MSc., Barbora Dvorakova, MSc., Boris Tichy, Dr., PhD., Jana Smardova, Prof., Martin Trbusek, Dr., PhD., Sim Truong, PhD., Katerina Stano-Kozubik, PhD., Nikola Tom, MSc., Karol Pal, MSc., Ludmila Sebejova, Dr., Nancy Patten, PhD., Lin Wu, PhD., Michael Doubek, M.D., PhD., Prof., Jiri Mayer, M.D., PhD., Prof., Sarka Pospisilova, Dr., PhD., Prof.
Journal: Blood
Blood (2012) 120 (21): 3911.
https://doi.org/10.1182/blood.V120.21.3911.3911
Published: 2012