1-18 of 18
Kendall J. Schick
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Chimeric Antigen Receptor Engineering of Mesenchymal Stromal Cells (CAR-MSC) Enhance Immunosuppression and Outcomes in Graft Versus Host Disease (GvHD) Preclinical Models

Olivia Sirpilla, Reona Leo Sakemura, Mehrdad Hefazi, James H. Girsch, Truc Huynh, Michelle J. Cox, Kendall J. Schick, Claudia Manriquez-Roman, Ismail Can, Kun Yun, Carli M. Stewart, Ekene J. Ogbodo, Elizabeth L. Siegler, Saad S. Kenderian
Journal: Blood
Blood (2022) 140 (Supplement 1): 1579–1580.
https://doi.org/10.1182/blood-2022-158872
Published: 2022
Journal Articles

Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma

Reona Sakemura, Mehrdad Hefazi, Elizabeth L. Siegler, Michelle J. Cox, Daniel P. Larson, Michael J. Hansen, Claudia Manriquez Roman, Kendall J. Schick, Ismail Can, Erin E. Tapper, Paulina Horvei, Mohamad M. Adada, Evandro D. Bezerra, Lionel Aurelien Kankeu Fonkoua, Michael W. Ruff, Wendy K. Nevala, Denise K. Walters, Sameer A. Parikh, Yi Lin, Diane F. Jelinek, Neil E. Kay, P. Leif Bergsagel, Saad S. Kenderian
Journal: Blood
Blood (2022) 139 (26): 3708–3721.
https://doi.org/10.1182/blood.2021012811
Published: 2022
Includes: Supplemental data
Journal Articles

Favorable Modulation of Chimeric Antigen Receptor T Cells Safety and Efficacy By the Non-Covalent BTK Inhibitor Vecabrutinib

Mohamad M. Adada, Reona Sakemura, Michelle J. Cox, Caludia Manriquez-Roman, Elizabeth L. Siegler, Erin E. Tapper, Carli M. Stewart, Kendall J. Schick, Ismail Can, Ekene J. Ogbodo, Evandro D. Bezerra, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Pietro Taverna, Judith A. Fox, Gloria Olivier, Susan L. Slager, Wei Ding, Sameer A. Parikh, Neil E. Kay, Saad S. Kenderian
Journal: Blood
Blood (2021) 138 (Supplement 1): 906.
https://doi.org/10.1182/blood-2021-151073
Published: 2021
Journal Articles

TNFR2 As a Target to Improve CD19-Directed CART Cell Fitness and Antitumor Activity in Large B Cell Lymphoma

Claudia Manriquez Roman, Michelle J. Cox, Reona Sakemura, Kun Yun, Mohamad M. Adada, Elizabeth L. Siegler, Olivia Sirpilla, Erin E. Tapper, Carli M. Stewart, Ekene J. Ogbodo, Ismail Can, Kendall J. Schick, Evandro D. Bezerra, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Wei Ding, Sameer A. Parikh, Susan L. Slager, Neil E. Kay, Gloria Olivier, Nathalie Scholler, Adrian Bot, Mike Mattie, Jenny J. Kim, Simone Filosto, Saad S. Kenderian
Journal: Blood
Blood (2021) 138 (Supplement 1): 901.
https://doi.org/10.1182/blood-2021-148591
Published: 2021
Journal Articles

The Impact of Prior Treatment with a CD19 Targeting Monoclonal Antibody on Subsequent Treatment with CD19 Targeting CART Cell Therapy in Preclinical Models

Reona Sakemura, Paulina Horvei, Claudia Manriquez-Roman, Ekene J. Ogbodo, Erin E. Tapper, Elizabeth L. Siegler, Carli M. Stewart, Kendall J. Schick, Ismail Can, Mohamad M. Adada, Evandro D. Bezerra, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Christian Augsberger, Juergen Schanzer, Maria Patra-Kneuer, Christina Heitmüller, Stefan Steidl, Jan Endell, Wei Ding, Sameer A. Parikh, Susan L. Slager, Neil E. Kay, Grzegorz S. Nowakowski, Michelle J. Cox, Saad S. Kenderian
Journal: Blood
Blood (2021) 138 (Supplement 1): 2412.
https://doi.org/10.1182/blood-2021-145649
Published: 2021
Journal Articles

Optimized Inhibition of GM-CSF in Preclinical Models of Anti-CD19 Chimeric Antigen Receptor T Cell Therapy

Evandro D. Bezerra, Reona Sakemura, James Girsch, Carli M. Stewart, Gunjan A Awatramani, Claudia Manriquez-Roman, Kendall J. Schick, Ismail Can, Ekene J. Ogbodo, Erin E. Tapper, Elizabeth L. Siegler, Mohamad M. Adada, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Susan L. Slager, Sameer A. Parikh, Neil E. Kay, Cameron Durrant, Omar Ahmed, Dale Chappell, Michelle J. Cox, Saad S. Kenderian
Journal: Blood
Blood (2021) 138 (Supplement 1): 2777.
https://doi.org/10.1182/blood-2021-149859
Published: 2021
Journal Articles

Axl-RTK Inhibition Modulates Monocyte Immune Response to Enhance the Anti-Tumor Effects of CD19 Redirected Chimeric Antigen Receptor T Cells in Preclinical Models

Reona Sakemura, MDPhD, Michelle J. Cox, Elizabeth L. Siegler, PhD, Erin E. Tapper, Wendy K. Nevala, Mehrdad Hefazi, MD, Claudia Manriquez Roman, Kendall J. Schick, Ismail Can, Evandro D. Bezerra, MD, Lionel Kankeu Fonkoua, MD, Paulina Horvei, MD, Michael W. Ruff, MD, Lars Mouritsen, Jason M. Foulks, PhD, Steven L. Warner, PhD, Wei Ding, MD PhD, Susan L. Slager, PhD, Sameer A. Parikh, MD, Neil E. Kay, MD, Saad S. Kenderian, MB, ChB
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-142159
Published: 2020
Journal Articles

Vesicular Stomatitis Virus (VSV) Engineered to Express CD19 Stimulates Anti-CD19 Chimeric Antigen Receptor Modified T Cells and Promotes Their Anti-Tumor Effects

Reona Sakemura, MDPhD, Elizabeth C. Eckert, PhD, Sydney B. Crotts, Linh Pham, Elizabeth L. Siegler, PhD, Michelle J. Cox, Erin E. Tapper, Mehrdad Hefazi, MD, Claudia Manriquez Roman, Kendall J. Schick, Ismail Can, Evandro D. Bezerra, MD, Lionel Kankeu Fonkoua, MD, Paulina Horvei, MD, Michael W. Ruff, MD, Susan L. Slager, PhD, Sameer A. Parikh, MD, Neil E. Kay, MD, Kah-Whye Peng, PhD, Stephen J. Russell, MD PhD, Saad S. Kenderian, MB, ChB
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-139647
Published: 2020
Journal Articles

Efficient Gene Editing of CART Cells with CRISPR-Cas12a for Enhanced Antitumor Efficacy

Elizabeth L. Siegler, PhD, Brandon W Simone, Reona Sakemura, MDPhD, Erin E. Tapper, Paulina Horvei, MD, Michelle J. Cox, Mehrdad Hefazi, MD, Claudia Manriquez Roman, Ismail Can, Kendall J. Schick, Michael W. Ruff, MD, Stephen C Ekker, PhD, Saad S. Kenderian, MB, ChB
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
https://doi.org/10.1182/blood-2020-141115
Published: 2020
Journal Articles

Targeting of CD19 By Tafasitamab Does Not Impair CD19 Directed Chimeric Antigen Receptor T Cell Activity in Vitro

Paulina Horvei, MD, Reona Sakemura, MD PhD, Michelle J. Cox, Michael W. Ruff, MD, Mehrdad Hefazi, MD, Erin E. Tapper, Kendall J. Schick, Claudia Manriquez Roman, Charles J. Kuhlmann, Juergen Schanzer, Jan Endell, Grzegorz Nowakowski, MD, Neil E. Kay, MD, Saad S. Kenderian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2859.
https://doi.org/10.1182/blood-2019-130506
Published: 2019
Journal Articles

Circulating Extracellular Vesicles Induce Chimeric Antigen Receptor T Cell Dysfunction in Chronic Lymphocytic Leukemia (CLL)

Michelle J. Cox, Fabrice Lucien-Matteoni, PhD, Reona Sakemura, MD PhD, Justin C. Boysen, Yohan Kim, MS, Michael J. Hansen, Claudia Manriquez Roman, Erin E. Tapper, Sydney B. Crotts, Kendall J. Schick, Mehrdad Hefazi, MD, Paulina Roman Moreno, MD, Michael W. Ruff, MD, Sameer A. Parikh, MD, Neil E. Kay, MD, Saad S. Kenderian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 679.
https://doi.org/10.1182/blood-2019-125272
Published: 2019
Journal Articles

Targeting Cancer Associated Fibroblasts in the Bone Marrow Prevents Resistance to Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma

Reona Sakemura, MD PhD, Michelle J. Cox, Michael J. Hansen, Mehrdad Hefazi, MD, Claudia Manriquez Roman, Kendall J. Schick, Erin E. Tapper, Paulina Roman Moreno, MD, Michael W. Ruff, MD, Denise K Walters, PhD BSc, Sameer A. Parikh, MD, Neil E. Kay, MD, Saad S. Kenderian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 865.
https://doi.org/10.1182/blood-2019-123277
Published: 2019
Journal Articles

Development of a Sensitive and Efficient Reporter Platform for the Detection of Chimeric Antigen Receptor T Cell Expansion, Trafficking, and Toxicity

Reona Sakemura, MD PhD, Lukkana Suksanpaisan, PhD, Roman H Khadka, Alysha N Newsom, Michael J. Hansen, Michelle J. Cox, Mehrdad Hefazi, MD, Claudia Manriquez Roman, Kendall J. Schick, Erin E. Tapper, Paulina Roman Moreno, MD, Michael W. Ruff, MD, Sameer A. Parikh, MD, Neil E. Kay, MD, Kah-Whye Peng, PhD, Stephen J Russell, MD PhD, Saad S. Kenderian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 53.
https://doi.org/10.1182/blood-2019-123476
Published: 2019
Journal Articles

Improved Anti-Tumor Response of Chimeric Antigen Receptor T Cell (CART) Therapy after GM-CSF Inhibition Is Mechanistically Supported By a Novel Direct Interaction of GM-CSF with Activated Carts

Michelle J. Cox, Charles J. Kuhlmann, Rosalie M. Sterner, Reona Sakemura, MD PhD, Sutapa Sinha, PhD, Raphael Mwangi, MS, Nancy Scott, MS, Mehrdad Hefazi, MD, Omar Ahmed, Dale Chappell, Cameron Durrant, Claudia Manriquez Roman, Kendall J. Schick, Erin E. Tapper, Paulina Horvei, MD, Michael W. Ruff, MD, Sameer A. Parikh, MD, Neil E. Kay, MD, Saad S. Kenderian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3868.
https://doi.org/10.1182/blood-2019-129349
Published: 2019
Journal Articles

GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts

Rosalie M. Sterner, Reona Sakemura, Michelle J. Cox, Nan Yang, Roman H. Khadka, Cynthia L. Forsman, Michael J. Hansen, Fang Jin, Katayoun Ayasoufi, Mehrdad Hefazi, Kendall J. Schick, Denise K. Walters, Omar Ahmed, Dale Chappell, Tarek Sahmoud, Cameron Durrant, Wendy K. Nevala, Mrinal M. Patnaik, Larry R. Pease, Karen E. Hedin, Neil E. Kay, Aaron J. Johnson, Saad S. Kenderian
Journal: Blood
Blood (2019) 133 (7): 697–709.
https://doi.org/10.1182/blood-2018-10-881722
Published: 2019
Includes: Supplemental data
Journal Articles

GM-CSF Blockade during Chimeric Antigen Receptor T Cell Therapy Reduces Cytokine Release Syndrome and Neurotoxicity and May Enhance Their Effector Functions

Rosalie M. Sterner, Reona Sakemura, MD PhD, Nan Yang, MD, Michelle J. Cox, Roman H. Khadka, Cynthia L. Forsman, PhD, Michael J. Hansen, Fang Jin, Katayoun Ayasoufi, Mehrdad Hefazi, MD, Baustin M. Welch, Kendall J. Schick, Denise K Walters, PhD, German Martinez, Omar Ahmed, Tarek Sahmoud, Cameron Durrant, Wendy K. Nevala, Mrinal M. Patnaik, MDMBBS, Stephen J. Russell, MD PhD, Larry Pease, Neil E. Kay, MD, Karen E. Hedin, Aaron J. Johnson, Saad S. Kenderian, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 961.
https://doi.org/10.1182/blood-2018-99-111766
Published: 2018
Journal Articles

Axl-RTK Inhibition Modulates T Cell Functions and Synergizes with Chimeric Antigen Receptor T Cell Therapy in B Cell Malignancies

Reona Sakemura, MD PhD, Nan Yang, MD, Michelle J. Cox, Sutapa Sinha, PhD, Mehrdad Hefazi, MD, Michael J. Hansen, Kendall J. Schick, Cynthia L. Forsman, PhD, Justin C. Boysen, Renee C Tschumper, Elizabeth Juarez Diaz, BS, Lars Mouritsen, Jason M Foulks, PhD, Steven L. Warner, PhD, Sameer A. Parikh, MD, Wei Ding, MD PhD, Neil E. Kay, MD, Saad S. Kenderian, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 728.
https://doi.org/10.1182/blood-2018-99-112209
Published: 2018
Journal Articles

Size Matters: Identification of Larger Size CD19 Positive Extracellular Vesicles in Chronic Lymphocytic Leukemia That Inhibit Chimeric Antigen Receptor T Cell Functions

Cynthia L. Forsman, PhD, Reona Sakemura, MD PhD, Fabrice Lucien-Matteoni, PhD, Elizabeth Juarez-Diaz, B.S., Nan Yang, MD, Michelle J. Cox, Sutapa Sinha, PhD, Mehrdad Hefazi, MD, Kendall J. Schick, Justin C. Boysen, Sameer A. Parikh, MD, Hon Sing Leong, PhD, Neil E. Kay, MD, Saad S. Kenderian, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1865.
https://doi.org/10.1182/blood-2018-99-119484
Published: 2018