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Kirby D Johnson
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Journal Articles

Interconnections between DDX41-Dependent Post-Transcriptional and GATA Factor-Instigated Transcriptional Mechanisms That Govern Hematopoiesis

Christina Jurotich, Jeong-Ah Kim, Kirby D. Johnson, Siqi Shen, Ruiqi Liao, Jane E Churpek, Sunduz Keles, Emery H. Bresnick
Journal: Blood
Blood (2023) 142 (Supplement 1): 1073.
https://doi.org/10.1182/blood-2023-182319
Published: 2023
Journal Articles

Genomic Determinants of Hematopoietic Progenitor Sensitivity to Innate Immune Signaling

Vu L. Tran, Peng Liu, Alexandra A. Soukup, Audrey Kopp, Bjorn M. Schoff, Ashley E. Mattina, Mabel M. Jung, Marjorie Brand, Kirby D. Johnson, Emery H. Bresnick
Journal: Blood
Blood (2023) 142 (Supplement 1): 5577.
https://doi.org/10.1182/blood-2023-186320
Published: 2023
Journal Articles

Spacing Constraints of Neighboring Zinc Finger Modules within GATA2

Mabel M. Jung, Koichi R. Katsumura, Peng Liu, Kirby D. Johnson, Joel P. Mackay, Lucy A. Godley, Emery H. Bresnick
Journal: Blood
Blood (2021) 138 (Supplement 1): 3306.
https://doi.org/10.1182/blood-2021-153023
Published: 2021
Journal Articles

Linking GATA2 Deficiency to Dysregulated Innate Immune Signaling

Vu L. Tran, Kirby D. Johnson, Koichi R. Katsumura, Emery H. Bresnick
Journal: Blood
Blood (2021) 138 (Supplement 1): 1081.
https://doi.org/10.1182/blood-2021-153340
Published: 2021
Journal Articles

Conditionally Pathogenic Genetic Variants of a Hematopoietic Disease-Suppressing Enhancer

Alexandra Soukup, Kirby D. Johnson, Peng Liu, Daniel R Matson, Emery H. Bresnick
Journal: Blood
Blood (2021) 138 (Supplement 1): 1078.
https://doi.org/10.1182/blood-2021-151008
Published: 2021
Journal Articles

GATA2 Enhancer Modules Governing Hematopoietic Regeneration

Alexandra A Soukup, PhD, Daniel R Matson, MD PhD, Kirby D Johnson, PhD, Emery H Bresnick, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-142867
Published: 2020
Journal Articles

GATA2 -Dependent Developmental and Regenerative Networks

Alexandra Soukup, PhD, Kirby D Johnson, PhD, Daniel J Conn, PhD, Evgenia Shishkova, PhD, Koichi Ricardo Katsumura, MD PhD, Peng Liu, PhD, Erik A. Ranheim, MD PhD, Katherine R. Calvo, MD PhD, Amy P. Hsu, Steven M. Holland, MD, Joshua J Coon, PhD, Sunduz Keles, PhD, Emery H Bresnick, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1182.
https://doi.org/10.1182/blood-2019-126875
Published: 2019
Journal Articles

Loss-of-Function and Gain-of-Function Consequences of GATA2 Disease Mutations

Koichi Ricardo Katsumura, MD PhD, Peng Liu, PhD, Charu Mehta, MS, Kyle J Hewitt, PhD, Alexandra Soukup, PhD, Isabela J Fraga de Andrade, Bachelors in Biological Science, Erik A. Ranheim, MD PhD, Kirby D Johnson, PhD, Emery H Bresnick, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2519.
https://doi.org/10.1182/blood-2019-129447
Published: 2019
Journal Articles

Single-Nucleotide Human Disease Mutation Inactivates a Blood-Regenerative Enhancer

Alexandra Soukup, BS, PhD, Charu Mehta, MS, Peng Liu, PhD, Miao Cao, Inga Hofmann, MD, Yun Zhou, MS, Jing Zhang, PhD, Kyunghee Choi, PhD, Kirby D Johnson, PhD, Emery H Bresnick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2564.
https://doi.org/10.1182/blood-2018-99-113008
Published: 2018
Journal Articles

Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program

Charu Mehta, MS, Kirby D Johnson, Xin Gao, Irene Ong, Koichi Ricardo Katsumura, MD PhD, Skye Courtney McIver, PhD, Erik A. Ranheim, MD PhD, Emery H Bresnick, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 7.
https://doi.org/10.1182/blood.V130.Suppl_1.7.7
Published: 2017
Journal Articles

p53 −/− synergizes with enhanced Nras G12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia

Jingfang Zhang, Guangyao Kong, Adhithi Rajagopalan, Li Lu, Jingming Song, Mohamed Hussaini, Xinmin Zhang, Erik A. Ranheim, Yangang Liu, Jinyong Wang, Xin Gao, Yuan-I Chang, Kirby D. Johnson, Yun Zhou, David Yang, Bhavana Bhatnagar, David M. Lucas, Emery H. Bresnick, Xuehua Zhong, Eric Padron, Jing Zhang
Journal: Blood
Blood (2017) 129 (3): 358–370.
https://doi.org/10.1182/blood-2016-06-719237
Published: 2017
Includes: Supplemental data
Journal Articles

A GATA-2-GPR65 Regulatory Module Controls Hematopoietic Stem Cell Generation

Xin Gao, Tongyu Wu, Jamie Lahvic, Kirby D. Johnson, Erik A. Ranheim, MD, Leonard I. Zon, MD, Emery H Bresnick, PhD
Journal: Blood
Blood (2015) 126 (23): 1176.
https://doi.org/10.1182/blood.V126.23.1176.1176
Published: 2015
Journal Articles

Mouse Modeling of GATA2 Related MDS/AML

Lisa J. McReynolds, MD PhD, Peter D. Aplan, MD, Donald Small, MD PhD, Li Ding, MD, Kirby D. Johnson, Emery H Bresnick, PhD, Steven M. Holland, MD
Journal: Blood
Blood (2015) 126 (23): 2855.
https://doi.org/10.1182/blood.V126.23.2855.2855
Published: 2015
Journal Articles

Cistrome Control of Hematopoieitic Stem/Progenitor Cell Function

Kyle Hewitt, PhD, Kirby D. Johnson, Duk-Hyoung Kim, Prithvia Devadas, Rajalekshmi Prathibha, Chandler Zuo, Colin Dewey, Rajendran Sanalkumar, Jin-Soo Kim, Sunduz Keles, Emery H Bresnick, PhD
Journal: Blood
Blood (2015) 126 (23): 43.
https://doi.org/10.1182/blood.V126.23.43.43
Published: 2015
Journal Articles

Genetic Basis For Hematopoietic Stem Cell Generation In The Mammalian Embryo

Xin Gao, Kirby D Johnson, PhD, Yuan-I Chang, PhD, Meghan E Boyer, Colin N Dewey, PhD, Jing Zhang, PhD, Emery Bresnick, PhD
Journal: Blood
Blood (2013) 122 (21): 3667.
https://doi.org/10.1182/blood.V122.21.3667.3667
Published: 2013
Journal Articles

Mechanistic Deficits Of a Leukemogenic GATA-2 Mutant

Koichi Ricardo Katsumura, MD/PhD, Chenxi Yang, Jing Zhang, PhD, Lingjun Li, PhD, Kirby D Johnson, PhD, Emery H Bresnick, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 3668.
https://doi.org/10.1182/blood.V122.21.3668.3668
Published: 2013
Journal Articles

GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome

Amy P. Hsu, Kirby D. Johnson, E. Liana Falcone, Rajendran Sanalkumar, Lauren Sanchez, Dennis D. Hickstein, Jennifer Cuellar-Rodriguez, Jacob E. Lemieux, Christa S. Zerbe, Emery H. Bresnick, Steven M. Holland
Journal: Blood
Blood (2013) 121 (19): 3830–3837.
https://doi.org/10.1182/blood-2012-08-452763
Published: 2013
Includes: Supplemental data
Journal Articles

Genetic Determinants of the Definitive Hematopoietic Stem/Progenitor Cell Compartment

Kirby D Johnson, PhD, Xin Gao, Rajendran Sanalkumar, PhD, Amy P Hsu, BA, Myung-Jeom Ryu, PhD, Jinyong Wang, PhD, Meghan E Boyer, Yangang Liu, Katherine R Calvo, MD, PhD, Sunduz Keles, PhD, Jing Zhang, PhD, Steven M. Holland, MD, Emery H Bresnick, PhD
Journal: Blood
Blood (2012) 120 (21): 1226.
https://doi.org/10.1182/blood.V120.21.1226.1226
Published: 2012
Journal Articles

A “Master Regulatory Cis -element” Governs the Hematopoietic Stem/Progenitor Cell Compartment, Vascular Integrity, and Cardiovascular Development

Kirby D Johnson, Myung-Jeom Ryu, Meghan E Boyer, Sunduz Kelez, Jing Zhang, Youngsook Lee, Emery H Bresnick, PhD
Journal: Blood
Blood (2011) 118 (21): 1304.
https://doi.org/10.1182/blood.V118.21.1304.1304
Published: 2011
Journal Articles

Context-dependent function of “GATA switch” sites in vivo

Brief Report
Jonathan W. Snow, Jennifer J. Trowbridge, Kirby D. Johnson, Tohru Fujiwara, Nikla E. Emambokus, Jeffrey A. Grass, Stuart H. Orkin, Emery H. Bresnick
Journal: Blood
Blood (2011) 117 (18): 4769–4772.
https://doi.org/10.1182/blood-2010-10-313031
Published: 2011
Includes: Supplemental data