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Journal Articles

Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation

Blood (2022) 139 (7): 1066–1079.

https://doi.org/10.1182/blood.2021012519

Published: 2022

Includes: Supplemental data

Journal Articles

Nras Q61R/+ and Kras −/− cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors

Zhi Wen, Grant Yun, Alexander Hebert, Guangyao Kong, Erik A. Ranheim, Remington Finn, Adhithi Rajagoplan, Shuyi Li, Yun Zhou, Mei Yu, Alisa Damnernsawad, Jeroen P. Roose, Joshua J. Coon, Renren Wen, Demin Wang, Jing Zhang

Blood (2021) 137 (23): 3259–3271.

https://doi.org/10.1182/blood.2020009082

Published: 2021

Includes: Supplemental data

Journal Articles

Expression of Nras Q61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice

Blood (2021) 137 (1): 61–74.

https://doi.org/10.1182/blood.2020007156

Published: 2021

Includes: Supplemental data

Journal Articles

GATA2 -Dependent Developmental and Regenerative Networks

Alexandra Soukup, PhD, Kirby D Johnson, PhD, Daniel J Conn, PhD, Evgenia Shishkova, PhD, Koichi Ricardo Katsumura, MD PhD, Peng Liu, PhD, Erik A. Ranheim, MD PhD, Katherine R. Calvo, MD PhD, Amy P. Hsu, Steven M. Holland, MD, Joshua J Coon, PhD, Sunduz Keles, PhD, Emery H Bresnick, PhD

Blood (2019) 134 (Supplement_1): 1182.

https://doi.org/10.1182/blood-2019-126875

Published: 2019

Journal Articles

Loss-of-Function and Gain-of-Function Consequences of GATA2 Disease Mutations

Koichi Ricardo Katsumura, MD PhD, Peng Liu, PhD, Charu Mehta, MS, Kyle J Hewitt, PhD, Alexandra Soukup, PhD, Isabela J Fraga de Andrade, Bachelors in Biological Science, Erik A. Ranheim, MD PhD, Kirby D Johnson, PhD, Emery H Bresnick, PhD

Blood (2019) 134 (Supplement_1): 2519.

https://doi.org/10.1182/blood-2019-129447

Published: 2019

Journal Articles

Elucidating an Erythroblast Survival Mechanism: Differential Contributions of Exosome Complex Catalytic Subunits

Charu Mehta, MS, Isabela J Fraga de Andrade, Bachelors in Biological Science, Nobuyuki Tanimura, PhD, Gary M Wilson, Erik A. Ranheim, MD PhD, Joshua J Coon, PhD, Emery H Bresnick, PhD

Blood (2019) 134 (Supplement_1): 155.

https://doi.org/10.1182/blood-2019-126917

Published: 2019

Journal Articles

Loss of Asxl1 Cooperates with Oncogenic Nras to Drive CMML Progression

Xiaona You, PhD, Zhi Wen, PhD, Guangyao Kong, Adhithi Rajagopalan, BS, Erik A. Ranheim, MD PhD, Yun Zhou, MS, Mrinal M Patnaik, MDMBBS, Jing Zhang, PhD

Blood (2019) 134 (Supplement_1): 3790.

https://doi.org/10.1182/blood-2019-131347

Published: 2019

Journal Articles

Unique dependence on Sos1 in Kras G12D -induced leukemogenesis

Xiaona You, Guangyao Kong, Erik A. Ranheim, David Yang, Yun Zhou, Jing Zhang

Blood (2018) 132 (24): 2575–2579.

https://doi.org/10.1182/blood-2018-09-874107

Published: 2018

Includes: Supplemental data

Journal Articles

A Longitudinal Toxicity over Time (ToxT) Analysis of Bortezomib When Added to Bendamustine-Rituximab (BR) in Previously Untreated High Risk (HR) Follicular Lymphoma (FL) from in E2408

Fangxin Hong, PhD, Andrew M. Evens, DO, MSc, Paul J Novotny, M.S., Thomas M. Habermann, MD, Ranjana H Advani, MD, Randy D. Gascoyne, MD, Thomas E. Witzig, MD, Andrew Quon, MD, Erik A. Ranheim, MD PhD, Amylou C. Dueck, PhD, Brad S Kahl, MD, Gita Thanarajasingam, MD

Blood (2018) 132 (Supplement 1): 4157.

https://doi.org/10.1182/blood-2018-99-117249

Published: 2018

Journal Articles

Mice Expressing MYC and Nras Q61R in Germinal Center B Cells Develop Highly Aggressive Multiple Myeloma

Adhithi Rajagopalan, BS, Zhi Wen, PhD, Quinlan Furumo, Erik A. Ranheim, MD PhD, Remington Finn, Evan Flietner, BS, Grant Yun, Yun Zhou, MS, Mei Yu, PhD, Natalie Scott Callander, MD, Marta Chesi, PhD, P. Leif Bergsagel, MD, Robert Burns, PhD, Demin Wang, PhD, Fotios Asimakopoulos, PhDMBBChir,, Jing Zhang, PhD

Blood (2018) 132 (Supplement 1): 1006.

https://doi.org/10.1182/blood-2018-99-116757

Published: 2018

Journal Articles

The Prognostic Impact of Baseline Positron Emission Tomography (PET) Imaging in Untreated High Risk (HR) Follicular Lymphoma (FL): Analysis from E2408, the Bortezomib Induction or Novel Imid® Continuation (BIONIC) Study

Lucia Baratto, MD, Opeyemi Jegede, PhD, Fangxin Hong, PhD, Thomas M. Habermann, MD, Ranjana Advani, MD, Randy D. Gascoyne, MD, Lale Kostakoglu, MD, Thomas E. Witzig, MD, Erik A. Ranheim, MD PhD, Brad S Kahl, MD, Andrew Quon, MD, Andrew M. Evens, DO, MSc

Blood (2018) 132 (Supplement 1): 1615.

https://doi.org/10.1182/blood-2018-99-113247

Published: 2018

Journal Articles

Canonical Notch Signaling Is Required for Kras G12D -Induced Myeloproliferative Neoplasm

Xiaona You, PhD, Guangyao Kong, Zhi Wen, Yuan-I Chang, Erik A. Ranheim, MD PhD, Eric Padron, MD, Jing Zhang, PhD

Blood (2017) 130 (Supplement 1): 1220.

https://doi.org/10.1182/blood.V130.Suppl_1.1220.1220

Published: 2017

Journal Articles

Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program

Charu Mehta, MS, Kirby D Johnson, Xin Gao, Irene Ong, Koichi Ricardo Katsumura, MD PhD, Skye Courtney McIver, PhD, Erik A. Ranheim, MD PhD, Emery H Bresnick, PhD

Blood (2017) 130 (Supplement 1): 7.

https://doi.org/10.1182/blood.V130.Suppl_1.7.7

Published: 2017

Journal Articles

A 3-Arm Randomized Phase II Trial with Bendamustine/Rituximab Therapy in Untreated High Risk (HR) Follicular Lymphoma (FL): Bortezomib Induction or Novel IMiD ® Continuation (BIONIC) Study from the ECOG-ACRIN Cancer Research Group

Andrew M Evens, DO,MSc, Fangxin Hong, PhD, Thomas M Habermann, MD, Ranjana H. Advani, MD, Randy D. Gascoyne, MD, Thomas E Witzig, MD, Andrew Quon, MD, Erik A. Ranheim, MD PhD, Puneet Cheema, MD, Philip Dy, MD, Timothy E. O'Brien, MD, Jane N. Winter, MD, Terrence Paul Cescon, Julie Chang, MD, Brad S Kahl, MD

Blood (2017) 130 (Supplement 1): 482.

https://doi.org/10.1182/blood.V130.Suppl_1.482.482

Published: 2017

Journal Articles

p53 −/− synergizes with enhanced Nras G12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia

Blood (2017) 129 (3): 358–370.

https://doi.org/10.1182/blood-2016-06-719237

Published: 2017

Includes: Supplemental data

Journal Articles

Dnmt3a Haploisufficiency Cooperates with Oncogenic Kras to Promote an Early-Onset T-Cell Leukemia

Yuan-I Chang, PhD, Guangyao Kong, PhD, Jing Zhang, PhD, Erik A. Ranheim, MD

Blood (2016) 128 (22): 2729.

https://doi.org/10.1182/blood.V128.22.2729.2729

Published: 2016

Journal Articles

Loss of Sos1 Inhibits Oncogenic Kras-Induced Hyperactivation of Wild-Type Ras during Leukemogenesis

Xiaona You, PhD, Guangyao Kong, PhD, Erik A. Ranheim, MD, Yun Zhou, Jing Zhang

Blood (2016) 128 (22): 1543.

https://doi.org/10.1182/blood.V128.22.1543.1543

Published: 2016

Journal Articles

Downregulating Notch Counteracts Kras G12D -Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative Neoplasm

Guangyao Kong, PhD, Yuan-I Chang, PhD, Jingfang Zhang, PhD, Erik A. Ranheim, MD, Xinmin Zhang, Yun Zhou, Yangang Liu, Lan Zhou, MD PhD, Warren S. Pear, MD PhD, Jing Zhang, PhD

Blood (2016) 128 (22): 1565.

https://doi.org/10.1182/blood.V128.22.1565.1565

Published: 2016

Journal Articles

A GATA-2-GPR65 Regulatory Module Controls Hematopoietic Stem Cell Generation

Xin Gao, Tongyu Wu, Jamie Lahvic, Kirby D. Johnson, Erik A. Ranheim, MD, Leonard I. Zon, MD, Emery H Bresnick, PhD

Blood (2015) 126 (23): 1176.

https://doi.org/10.1182/blood.V126.23.1176.1176

Published: 2015

Journal Articles

Downregulating Notch Signaling in Kras G12D/+ Mice Inhibits Both T-Cell Leukemia and Myeloproliferative Neoplasm in a Cell-Autonomous Manner

Guangyao Kong, PhD, Yuan-I Chang, PhD, Erik A. Ranheim, MD, Yun Zhou, Yangang Liu, Paul Lambert, PhD, Lan Zhou, MD PhD, Pamela Stanley, PhD, Warren S. Pear, MD PhD, Jing Zhang, PhD

Blood (2014) 124 (21): 261.

https://doi.org/10.1182/blood.V124.21.261.261

Published: 2014

NARROW

Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation

Nras Q61R/+ and Kras −/− cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors

Expression of Nras Q61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice

GATA2 -Dependent Developmental and Regenerative Networks

Loss-of-Function and Gain-of-Function Consequences of GATA2 Disease Mutations

Elucidating an Erythroblast Survival Mechanism: Differential Contributions of Exosome Complex Catalytic Subunits

Loss of Asxl1 Cooperates with Oncogenic Nras to Drive CMML Progression

Unique dependence on Sos1 in Kras G12D -induced leukemogenesis

A Longitudinal Toxicity over Time (ToxT) Analysis of Bortezomib When Added to Bendamustine-Rituximab (BR) in Previously Untreated High Risk (HR) Follicular Lymphoma (FL) from in E2408

Mice Expressing MYC and Nras Q61R in Germinal Center B Cells Develop Highly Aggressive Multiple Myeloma

The Prognostic Impact of Baseline Positron Emission Tomography (PET) Imaging in Untreated High Risk (HR) Follicular Lymphoma (FL): Analysis from E2408, the Bortezomib Induction or Novel Imid® Continuation (BIONIC) Study

Canonical Notch Signaling Is Required for Kras G12D -Induced Myeloproliferative Neoplasm

Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program

A 3-Arm Randomized Phase II Trial with Bendamustine/Rituximab Therapy in Untreated High Risk (HR) Follicular Lymphoma (FL): Bortezomib Induction or Novel IMiD ® Continuation (BIONIC) Study from the ECOG-ACRIN Cancer Research Group

p53 −/− synergizes with enhanced Nras G12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia

Dnmt3a Haploisufficiency Cooperates with Oncogenic Kras to Promote an Early-Onset T-Cell Leukemia

Loss of Sos1 Inhibits Oncogenic Kras-Induced Hyperactivation of Wild-Type Ras during Leukemogenesis

Downregulating Notch Counteracts Kras G12D -Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative Neoplasm

A GATA-2-GPR65 Regulatory Module Controls Hematopoietic Stem Cell Generation

Downregulating Notch Signaling in Kras G12D/+ Mice Inhibits Both T-Cell Leukemia and Myeloproliferative Neoplasm in a Cell-Autonomous Manner

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American Society of Hematology

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ASH Publications

American Society of Hematology

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