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Journal Articles

p53 −/− synergizes with enhanced Nras G12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia

Blood (2017) 129 (3): 358–370.

https://doi.org/10.1182/blood-2016-06-719237

Published: 2017

Includes: Supplemental data

Journal Articles

Downregulating Notch Counteracts Kras G12D -Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative Neoplasm

Guangyao Kong, PhD, Yuan-I Chang, PhD, Jingfang Zhang, PhD, Erik A. Ranheim, MD, Xinmin Zhang, Yun Zhou, Yangang Liu, Lan Zhou, MD PhD, Warren S. Pear, MD PhD, Jing Zhang, PhD

Blood (2016) 128 (22): 1565.

https://doi.org/10.1182/blood.V128.22.1565.1565

Published: 2016

Journal Articles

Downregulating Notch Signaling in Kras G12D/+ Mice Inhibits Both T-Cell Leukemia and Myeloproliferative Neoplasm in a Cell-Autonomous Manner

Guangyao Kong, PhD, Yuan-I Chang, PhD, Erik A. Ranheim, MD, Yun Zhou, Yangang Liu, Paul Lambert, PhD, Lan Zhou, MD PhD, Pamela Stanley, PhD, Warren S. Pear, MD PhD, Jing Zhang, PhD

Blood (2014) 124 (21): 261.

https://doi.org/10.1182/blood.V124.21.261.261

Published: 2014

Journal Articles

Kras Plays An Important Role In Generating Differentiated Blood Cells

Alisa Damnernsawad, Guangyao Kong, PhD, Yangang Liu, Yuan-I Chang, PhD, Jingfang Zhang, Qiang Chang, Jing Zhang, PhD

Blood (2013) 122 (21): 2451.

https://doi.org/10.1182/blood.V122.21.2451.2451

Published: 2013

Journal Articles

Loss Of p53 Promotes Transformation Of Oncogenic Nras-Induced Chronic Myelomonocytic Leukemia To An Acute Phase

Jingfang Zhang, Yangang Liu, Guangyao Kong, PhD, Yuan-I Chang, PhD, Erik A. Ranheim, MD, Jinyong Wang, PhD, Juan Du, PhD, Alisa Damnernsawad, Jing Zhang, PhD

Blood (2013) 122 (21): 3790.

https://doi.org/10.1182/blood.V122.21.3790.3790

Published: 2013

Journal Articles

Nras G12D/+ promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions

Jinyong Wang, Guangyao Kong, Yangang Liu, Juan Du, Yuan-I Chang, Sin Ruow Tey, Xinmin Zhang, Erik A. Ranheim, Marc K. Saba-El-Leil, Sylvain Meloche, Alisa Damnernsawad, Jingfang Zhang, Jing Zhang

Blood (2013) 121 (26): 5203–5207.

https://doi.org/10.1182/blood-2012-12-475863

Published: 2013

Includes: Supplemental data

Journal Articles

Genetic Determinants of the Definitive Hematopoietic Stem/Progenitor Cell Compartment

Kirby D Johnson, PhD, Xin Gao, Rajendran Sanalkumar, PhD, Amy P Hsu, BA, Myung-Jeom Ryu, PhD, Jinyong Wang, PhD, Meghan E Boyer, Yangang Liu, Katherine R Calvo, MD, PhD, Sunduz Keles, PhD, Jing Zhang, PhD, Steven M. Holland, MD, Emery H Bresnick, PhD

Blood (2012) 120 (21): 1226.

https://doi.org/10.1182/blood.V120.21.1226.1226

Published: 2012

Journal Articles

Endogenous Nras G12D/+ and G12D/G12D Distinctly Regulate Self-Renewal and Differentiation of Haematopoietic Stem Cells

Guangyao Kong, Jinyong Wang, PhD, Yangang Liu, Juan Du, Alisa Damnernsawad, Erik A. Ranheim, MD, Myung-Jeom Ryu, PhD, Jing Zhang, PhD

Blood (2012) 120 (21): 4086.

https://doi.org/10.1182/blood.V120.21.4086.4086

Published: 2012

Journal Articles

Endogenous Oncogenic Nras Signaling Promotes Proliferative Exhaustion of Hematopoietic Stem Cells Through a Dose-Dependent Hyperactivation of ERK,

Jinyong Wang, PhD, Yangang Liu, Juan Du, Myung-Jeom Ryu, Erik A. Ranheim, MD, PhD, Jing Zhang

Blood (2011) 118 (21): 3997.

https://doi.org/10.1182/blood.V118.21.3997.3997

Published: 2011

Journal Articles

Role of CD44 in Endogenous Kras G12D -mediated Myeloproliferative Neoplasm

Juan Du, Yangang Liu, Lixuan Tan, Juinn Cherng Lo, Jinyong Wang, PhD, Myung-Joem Ryu, Jingfang Zhang, Jing Zhang

Blood (2011) 118 (21): 1398.

https://doi.org/10.1182/blood.V118.21.1398.1398

Published: 2011

Journal Articles

Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner

Jinyong Wang, Yangang Liu, Zeyang Li, Zhongde Wang, Li Xuan Tan, Myung-Jeom Ryu, Benjamin Meline, Juan Du, Ken H. Young, Erik Ranheim, Qiang Chang, Jing Zhang

Blood (2011) 118 (2): 368–379.

https://doi.org/10.1182/blood-2010-12-326058

Published: 2011

Includes: Supplemental data

Journal Articles

Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia

Jinyong Wang, Yangang Liu, Zeyang Li, Juan Du, Myung-Jeom Ryu, Philip R. Taylor, Mark D. Fleming, Ken H. Young, Henry Pitot, Jing Zhang

Blood (2010) 116 (26): 5991–6002.

https://doi.org/10.1182/blood-2010-04-281527

Published: 2010

Includes: Supplemental data

Journal Articles

Endogenous Oncogenic Nras Mutation Leads to Aberrant GM-CSF Signaling In Granulocytic/Monocytic Precursors In a Murine Model of Chronic Myelomonocytic Leukemia

Jinyong Wang, PhD, Yangang Liu, PhD, Zeyang Li, PhD, Juan Du, PhD, Myung-Jeom Ryu, PhD, Philip Taylor, Mark D. Fleming, MD, DPhil, Ken H Young, PhD, Henry Pitot, PhD, Jing Zhang, PhD

Blood (2010) 116 (21): 4180.

https://doi.org/10.1182/blood.V116.21.4180.4180

Published: 2010

Journal Articles

Endogenous Oncogenic Nras Mutation Initiates T-Cell Leukemia/Lymphoma In a Dose-Dependent Manner

Jinyong Wang, PhD, Zeyang Li, PhD, Zhongde Wang, PhD, Yangang Liu, PhD, Myung-Jeom Ryu, PhD, Benjamin Meline, PhD, Juan Du, PhD, Ken H Young, PhD, Qiang Chang, Jing Zhang, PhD

Blood (2010) 116 (21): 4183.

https://doi.org/10.1182/blood.V116.21.4183.4183

Published: 2010

Journal Articles

Oncogenic Kras -induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation

Jing Zhang, Jing Wang, Yangang Liu, Harwin Sidik, Ken H. Young, Harvey F. Lodish, Mark D. Fleming

Blood (2009) 113 (6): 1304–1314.

https://doi.org/10.1182/blood-2008-01-134262

Published: 2009

Includes: Supplemental data

Journal Articles

Expression of oncogenic K-ras from its endogenous promoter leads to a partial block of erythroid differentiation and hyperactivation of cytokine-dependent signaling pathways

Jing Zhang, Yangang Liu, Caroline Beard, David A. Tuveson, Rudolf Jaenisch, Tyler E. Jacks, Harvey F. Lodish

Blood (2007) 109 (12): 5238–5241.

https://doi.org/10.1182/blood-2006-09-047050

Published: 2007

Journal Articles

The Role of K-ras Signaling in Erythropoiesis In Vivo.

Jing Zhang, PhD, Yangang Liu, MS, Caroline Beard, Rudolf Jaenisch, MD, Tyler Jacks, Ph.D, Harvey F. Lodish, Ph.D

Blood (2005) 106 (11): 3136.

https://doi.org/10.1182/blood.V106.11.3136.3136

Published: 2005

NARROW

p53 −/− synergizes with enhanced Nras G12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia

Downregulating Notch Counteracts Kras G12D -Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative Neoplasm

Downregulating Notch Signaling in Kras G12D/+ Mice Inhibits Both T-Cell Leukemia and Myeloproliferative Neoplasm in a Cell-Autonomous Manner

Kras Plays An Important Role In Generating Differentiated Blood Cells

Loss Of p53 Promotes Transformation Of Oncogenic Nras-Induced Chronic Myelomonocytic Leukemia To An Acute Phase

Nras G12D/+ promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions

Genetic Determinants of the Definitive Hematopoietic Stem/Progenitor Cell Compartment

Endogenous Nras G12D/+ and G12D/G12D Distinctly Regulate Self-Renewal and Differentiation of Haematopoietic Stem Cells

Endogenous Oncogenic Nras Signaling Promotes Proliferative Exhaustion of Hematopoietic Stem Cells Through a Dose-Dependent Hyperactivation of ERK,

Role of CD44 in Endogenous Kras G12D -mediated Myeloproliferative Neoplasm

Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner

Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia

Endogenous Oncogenic Nras Mutation Leads to Aberrant GM-CSF Signaling In Granulocytic/Monocytic Precursors In a Murine Model of Chronic Myelomonocytic Leukemia

Endogenous Oncogenic Nras Mutation Initiates T-Cell Leukemia/Lymphoma In a Dose-Dependent Manner

Oncogenic Kras -induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation

Expression of oncogenic K-ras from its endogenous promoter leads to a partial block of erythroid differentiation and hyperactivation of cytokine-dependent signaling pathways

The Role of K-ras Signaling in Erythropoiesis In Vivo.

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American Society of Hematology

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American Society of Hematology

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