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Kylie Lepic
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Journal Articles

LSD1 inhibition enhances venetoclax efficacy in Acute Myeloid Leukemia via metabolic rewiring

Free
Kanwaldeep Singh, Emily Hartung, Anna Dvorkin-Gheva, Christina Muhs, Islam Alshamleh, Sara Pishyar, Pradhariny Prabagaran, Suhrid Banskota, Dina Khalaf, Ronan Foley, Alejandro Garcia-Horton, Brian Leber, Irwin Walker, Kylie Lepic, Frank Schnuetgen, Nina Kurrle, Harald Schwalbe, Hubert Serve, Maria Kleppe, Hugh Rienhoff, Gregory Steinberg, Tobias Berg
Journal: Blood
Blood (2025) 146 (Supplement 1): 3293.
https://doi.org/10.1182/blood-2025-3293
Published: 2025
Journal Articles

Clinically meaningful improvement of the modified lee symptom score in patients treated with belumosudil for steroid-refractory chronic GVHD: Evidence from Canadian real-world outcomes

Free
Sergio Rodriguez-Rodriguez, Nihar Desai, Brittany Salter, Amani Ahmed, Mohamed Elemary, Jonas Mattsson, Kylie Lepic, Jennifer White, Dennis Kim
Journal: Blood
Blood (2025) 146 (Supplement 1): 2470.
https://doi.org/10.1182/blood-2025-2470
Published: 2025
Journal Articles

Multicenter real-world experience of belumosudil treatment in heavily pretreated patients with steroid-refractory chronic graft-versus-host disease: Clinical outcomes and risk factor analysis for failure-free survival.

Free
Sergio Rodriguez-Rodriguez, Rebeca Bailen, Keven Vachon, Brittany Salter, Christopher Lemieux, Kareem Jamani, Mohamed Elemary, Sylvie Lachance, Jonas Mattsson, Kylie Lepic, Amani Ahmed, Jennifer White, Felipe Peña-Muñoz, Juan Alberto Martín González, Jose Antonio Perez Simon, Matthias Fante, Daniel Wolff, Mi Kwon, Dennis Kim
Journal: Blood
Blood (2025) 146 (Supplement 1): 4239.
https://doi.org/10.1182/blood-2025-4239
Published: 2025
Journal Articles

Propensity score matching analysis comparing the efficacy and treatment outcomes of belumosudil treatment with ruxolitinib therapy as second-line or beyond in chronic GVHD patients after steroid failure

Free
Sergio Rodriguez-Rodriguez, Rebeca Bailen, Keven Vachon, Brittany Salter, Christopher Lemieux, Kareem Jamani, Mohamed Elemary, Sylvie Lachance, Jonas Mattsson, Kylie Lepic, Amani Ahmed, Jennifer White, Felipe Peña-Muñoz, Juan Alberto Martín González, Jose Antonio Perez Simon, Matthias Fante, Daniel Wolff, Mi Kwon, Dennis Kim
Journal: Blood
Blood (2025) 146 (Supplement 1): 6031.
https://doi.org/10.1182/blood-2025-6031
Published: 2025
Journal Articles

Propensity score matching analysis comparing the efficacy and long-term outcomes of belumosudil to the best available treatment as a historical control, used as second-line therapy or beyond for chronic GVHD after steroid failure.

Free
Sergio Rodriguez-Rodriguez, Rebeca Bailen, Keven Vachon, Brittany Salter, Christopher Lemieux, Kareem Jamani, Mohamed Elemary, Sylvie Lachance, Jonas Mattsson, Kylie Lepic, Amani Ahmed, Jennifer White, Felipe Peña-Muñoz, Juan Alberto Martín González, Jose Antonio Perez Simon, Matthias Fante, Daniel Wolff, Mi Kwon, Dennis Kim
Journal: Blood
Blood (2025) 146 (Supplement 1): 6025.
https://doi.org/10.1182/blood-2025-6025
Published: 2025
Journal Articles

Multicenter Survey on the Practice Patterns of Post-Transplant Maintenance Treatment in FLT3-ITD Acute Myeloid Leukemia and Philadelphia Positive Acute Lymphoblastic Leukemia: What Is the Common Institutional Policy for Duration of Therapy?

Free
Alejandro Garcia-Horton, Imran Ahmad, Kylie Lepic, Christopher Lemieux, David Sanford, Mohamed Elemary, Kareem Jamani, Mohsen Al Zahrani, Muhned Alhumaid, Ahmad S. Alotaibi, Ayman Saad, Ahmad Alhuraiji, Murtadha Al-Khabori, Ali Bazarbachi, Robert Zeiser, Varun Mehra, Jae-Sook Ahn, Hyeoung-Joon Kim, Joon Ho Moon, Sang Kyun Sohn, Yu Cai, Xianmin Song, Xiao Jun Huang, Yishan Ye, He Huang, Hee-je Kim, Dennis Dong Hwan Kim
Journal: Blood
Blood (2024) 144 (Supplement 1): 7418.
https://doi.org/10.1182/blood-2024-206153
Published: 2024
Journal Articles

Development of an Electronic Learning Module for CAR-T Education in Canadian Hematology Residents

Free
Grace Zhang, Gwynivere A Davies, Kylie Lepic, Amaris K Balitsky
Journal: Blood
Blood (2024) 144 (Supplement 1): 3822.
https://doi.org/10.1182/blood-2024-200444
Published: 2024
Journal Articles

LSD1 Inhibition Synergizes with Venetoclax in Acute Myeloid Leukemia By Targeting Cellular Metabolism

Free
Kanwaldeep Singh, Emily Hartung, Christina Muhs, Islam Alshamleh, Monisha Divakaran, Anna Dvorkin-Gheva, Sara Pishyar, Pradhariny Prabagaran, Dina Khalaf, Alejandro Garcia-Horton, Stephen Ronan Foley, Brian Leber, Irwin Walker, Kylie Lepic, Harald Schwalbe, Hubert Serve, Maria Kleppe, Hugh Young Rienhoff, Jr., Tobias Berg
Journal: Blood
Blood (2023) 142 (Supplement 1): 4156.
https://doi.org/10.1182/blood-2023-189515
Published: 2023
Journal Articles

Comparison of Comorbidity Scores and the Impact of Comorbidities on Length of Stay and Survival in Patients with Non−Hodgkin's Lymphoma Treated with Autologous Stem Cell Transplant

Free
Kylie Lepic, MD, FRCPC, Ann Benger, MD, FRCP(C), Ronan Foley, MD, FRCPC, Graeme Fraser, Deborah Marcellus, MD, Michelle Saunders-Roy, RN, Michael Trus, MD, PhD, FRCPC, Anita Adams, RN(EC), MN, NP, CPMHN(C), Kari Kolm, RN(EC), MN, NP, Jennifer Wiernikowski, MN, NP, CON(C), C. Tom Kouroukis, MD, MSc, FRCPC
Journal: Blood
Blood (2011) 118 (21): 2091.
https://doi.org/10.1182/blood.V118.21.2091.2091
Published: 2011
Journal Articles

The Inappropriate Use of the SimpliRed D-Dimer Assay in the Diagnosis of Venous Thromboembolism,

Free
Kylie Lepic, MD, FRCPC, Anthony E. Naassan, MD, FRCPC, Mark A. Crowther, MD, FRCPC
Journal: Blood
Blood (2011) 118 (21): 4207.
https://doi.org/10.1182/blood.V118.21.4207.4207
Published: 2011