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Journal Articles

CD371-positive pediatric B-cell acute lymphoblastic leukemia: propensity to lineage switch and slow early response to treatment

Blood (2024) 143 (17): 1738–1751.

https://doi.org/10.1182/blood.2023021952

Published: 2024

Includes: Supplemental data

Journal Articles

Protocol II vs protocol III given twice during reinduction therapy in children with medium-risk ALL

Blood (2017) 130 (19): 2146–2149.

https://doi.org/10.1182/blood-2017-05-782086

Published: 2017

Includes: Supplemental data

Journal Articles

T/NK-Cell Immunophenotype with Coexpression of CD56 Predicts Poor Outcome in Childhood T-ALL. Results of the ALL-BFM 2000 Trial

Stephan Fuhrmann, MD, Leonid Karawajew, Richard Schabath, Anja Moricke, MD, Martin Zimmermann, PhD, Wolf-Dieter Ludwig, Martin Schrappe, MD PhD, Richard Ratei

Blood (2016) 128 (22): 760.

https://doi.org/10.1182/blood.V128.22.760.760

Published: 2016

Journal Articles

Validation of MRD Quantification By Flow Cytometry for Pediatric BCP ALL Relapsed Patients Treated on the Intreall Protocol

Blood (2015) 126 (23): 1414.

https://doi.org/10.1182/blood.V126.23.1414.1414

Published: 2015

Journal Articles

Intermediate-Risk Acute Lymphoblastic Leukemia (ALL) Patients with and without Relapse Differentially Depend on Survival Signals From Microenvironment

Peter Rhein, PhD, Rita Mitlohner, Renate Kirschner-Schwabe, PhD, Christian Hagemeier, MD, PhD, Gunnar Cario, MD, Martin Stanulla, MD, MSc, Martin Schrappe, MD, Iduna Fichtner, PhD, Richard Ratei, MD, Wolf-Dieter Ludwig, Leonid Karawajew, PhD

Blood (2011) 118 (21): 752.

https://doi.org/10.1182/blood.V118.21.752.752

Published: 2011

Journal Articles

High CD45 (PTPRC) Expression Is Associated with An Overall Poor Outcome in Childhood Acute Lymphoblastic Leukemia Treated on the ALL-BFM 2000 Protocol and Exerts An Especially Pronounced Effect in Intermediate Risk Patients

Gunnar Cario, MD, Rita Mitlohner, Martin Zimmermann, PhD, Renja Romey, Peter Rhein, PhD, André Schrauder, MD, Anja Moericke, MD, Jean-Pierre Bourquin, MD, PhD, Wolf-Dieter Ludwig, MD, Richard Ratei, MD, Martin Schrappe, MD, Leonid Karawajew, PhD, Martin Stanulla, MD, MSc

Blood (2011) 118 (21): 742.

https://doi.org/10.1182/blood.V118.21.742.742

Published: 2011

Journal Articles

CD11b is a therapy resistance– and minimal residual disease–specific marker in precursor B-cell acute lymphoblastic leukemia

Peter Rhein, Rita Mitlohner, Giuseppe Basso, Giuseppe Gaipa, Michael N. Dworzak, Renate Kirschner-Schwabe, Christian Hagemeier, Martin Stanulla, Martin Schrappe, Wolf-Dieter Ludwig, Leonid Karawajew, Richard Ratei

Blood (2010) 115 (18): 3763–3771.

https://doi.org/10.1182/blood-2009-10-247585

Published: 2010

Journal Articles

Time Point-Dependent Concordance of Flow Cytometry and RQ-PCR in the MRD Detection in Childhood ALL: The Experience of the AIEOP-BFM- ALL MRD Study Group

Giuseppe Gaipa, MD, Giovanni Cazzaniga, Renate E Panzer-Grümayer, Marinella Veltroni, Leonid Karawajew, Daniela Silvestri, Barbara Buldini, Richard Ratei, Andre Schrauder, Martin Schrappe, Wolf-Dieter Ludwig, Maria Grazia Valsecchi, Andrea Biondi, Michael N Dworzak, Giuseppe Basso

Blood (2008) 112 (11): 700.

https://doi.org/10.1182/blood.V112.11.700.700

Published: 2008

Journal Articles

Integrin Alpha M Chain Expression at Diagnosis Is Inversely Correlated with Cytoreduction Rate and Is Consistently Up-Regulated during Therapy in Acute Lymphoblastic Leukemia (ALL)

Peter Rhein, Richard Ratei, MD, Rita Mitlohner, Giuseppe Basso, MD, Giuseppe Gaipa, MD, Michael N Dworzak, MD, PhD, Martin Stanulla, MD, Martin Schrappe, MD, Wolf-Dieter Ludwig, MD, Leonid Karawajew, PhD

Blood (2008) 112 (11): 2526.

https://doi.org/10.1182/blood.V112.11.2526.2526

Published: 2008

Journal Articles

Intact apoptosis signaling in myeloid leukemia cells determines treatment outcome in childhood AML

Lüder H. Meyer, Manon Queudeville, Sarah M. Eckhoff, Ursula Creutzig, Dirk Reinhardt, Leonid Karawajew, Wolf-Dieter Ludwig, Karsten Stahnke, Klaus-Michael Debatin

Blood (2008) 111 (5): 2899–2903.

https://doi.org/10.1182/blood-2007-08-109058

Published: 2008

Includes: Supplemental data

Journal Articles

CD11b Is a Therapy-Induced Marker for Monitoring Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia.

Peter Rhein, Richard Ratei, M.D., Rita Mitlohner, Martin Schrappe, M.D., Wolf-Dieter Ludwig, M.D., Leonid Karawajew, Ph.D.

Blood (2007) 110 (11): 1424.

https://doi.org/10.1182/blood.V110.11.1424.1424

Published: 2007

Journal Articles

Significance of Copy Number Alterations for Molecular Treatment Response in Childhood Acute Lymphoblastic Leukemia.

Doris Steinemann, Dr.rer.nat., Gunnar Cario, Dr.med., Martin Stanulla, Dr.med., Leonid Karawajew, Dr.med., Marcel Tauscher, Anja Weigmann, Dr.rer.nat., Gudrun Göhring, Dr.med., Wolf-Dieter Ludwig, Dr.med., Jochen Harbott, Dr.med., Bernhard Radlwimmer, Dr.rer.nat., Claus-Rainer Bartram, Dr.med., Peter Lichter, Dr.rer.nat., Martin Schrappe, Dr.med., Brigitte Schlegelberger, Dr.med.

Blood (2007) 110 (11): 1434.

https://doi.org/10.1182/blood.V110.11.1434.1434

Published: 2007

Journal Articles

Favourable Treatment Outcome in Childhood AML Is Determined by Intact Apoptosis Signalling in Myeloid Leukaemia Cells.

Lüder H. Meyer, MD, Manon Dammé, Sarah M. Eckhoff, MD, Ursula Creutzig, MD, Dirk Reinhardt, MD, Leonid Karawajew, PhD, Wolf D. Ludwig, MD, Karsten Stahnke, MD, Klaus M. Debatin, MD

Blood (2007) 110 (11): 2842.

https://doi.org/10.1182/blood.V110.11.2842.2842

Published: 2007

Journal Articles

Glucocorticoid Therapy Targets Proliferation, Differentiation and Bcl-2 Dependent Survival Signaling in ALL Blasts.

Peter Rhein, Stefanie Scheid, Richard Ratei, MD, Christian Hagemeier, PhD, MD, Karl Seeger, PhD, MD, Renate Kirschner-Schwabe, PhD, Martin Schrappe, MD, Rainer Spang, PhD, Wolf-Dieter Ludwig, MD, Leonid Karawajew, PhD

Blood (2006) 108 (11): 1841.

https://doi.org/10.1182/blood.V108.11.1841.1841

Published: 2006

Journal Articles

Cytochrome c–related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL

Lüder Hinrich Meyer, Leonid Karawajew, Martin Schrappe, Wolf-Dieter Ludwig, Klaus-Michael Debatin, Karsten Stahnke

Blood (2006) 107 (11): 4524–4531.

https://doi.org/10.1182/blood-2005-08-3305

Published: 2006

Includes: Supplemental data

Journal Articles

Gene Expression in Leukemic Blasts Persisting at Day 8 of Induction Therapy in Childhood ALL Displays a Common Shift towards Terminally Differentiated B Cells and a Cytoreduction-Associated Impairment of the Translational Machinery.

Blood (2005) 106 (11): 537.

https://doi.org/10.1182/blood.V106.11.537.537

Published: 2005

Journal Articles

Stress-induced activation of the p53 tumor suppressor in leukemia cells and normal lymphocytes requires mitochondrial activity and reactive oxygen species

Leonid Karawajew, Peter Rhein, Grit Czerwony, Wolf-Dieter Ludwig

Blood (2005) 105 (12): 4767–4775.

https://doi.org/10.1182/blood-2004-09-3428

Published: 2005

Journal Articles

Differential Gene Expression in Leukemic Cells from Bone Marrow (BM) and Peripheral Blood (PB) of Pediatric Patients with Acute Lymphoblastic Leukemia (ALL).

Peter Rhein, Stefanie Scheid, Christian Hagemeier, Karl Seeger, Renate Kirschner, Martin Schrappe, Rainer Spang, Wolf-Dieter Ludwig, Leonid Karawajew

Blood (2004) 104 (11): 1889.

https://doi.org/10.1182/blood.V104.11.1889.1889

Published: 2004

Journal Articles

Gene Expression Analysis of Leukemic Blasts Persisting at Day 8 of Induction Therapy in Childhood ALL.

Peter Rhein, Richard Ratei, Stefanie Scheid, Christian Hagemeier, Karl Seeger, Renate Kirschner, Martin Schrappe, Rainer Spang, Wolf-Dieter Ludwig, Leonid Karawajew

Blood (2004) 104 (11): 522.

https://doi.org/10.1182/blood.V104.11.522.522

Published: 2004

Journal Articles

High Expression Levels of Iaps Predict Poor Overall Survival in Childhood De Novo Acute Myeloid Leukemia.

Ingo Tamm, M.D., Stephan Richter, Doreen Oltersdorf, Ursula Creutzig, M.D., Jochen Harbott, M.D., Frank Scholz, Ph.D., Leonid Karawajew, Ph.D., Wolf-Dieter Ludwig, M.D., Wuchter Christian, M.D.

Blood (2004) 104 (11): 4396.

https://doi.org/10.1182/blood.V104.11.4396.4396

Published: 2004

NARROW

CD371-positive pediatric B-cell acute lymphoblastic leukemia: propensity to lineage switch and slow early response to treatment

Protocol II vs protocol III given twice during reinduction therapy in children with medium-risk ALL

T/NK-Cell Immunophenotype with Coexpression of CD56 Predicts Poor Outcome in Childhood T-ALL. Results of the ALL-BFM 2000 Trial

Validation of MRD Quantification By Flow Cytometry for Pediatric BCP ALL Relapsed Patients Treated on the Intreall Protocol

Intermediate-Risk Acute Lymphoblastic Leukemia (ALL) Patients with and without Relapse Differentially Depend on Survival Signals From Microenvironment

High CD45 (PTPRC) Expression Is Associated with An Overall Poor Outcome in Childhood Acute Lymphoblastic Leukemia Treated on the ALL-BFM 2000 Protocol and Exerts An Especially Pronounced Effect in Intermediate Risk Patients

CD11b is a therapy resistance– and minimal residual disease–specific marker in precursor B-cell acute lymphoblastic leukemia

Time Point-Dependent Concordance of Flow Cytometry and RQ-PCR in the MRD Detection in Childhood ALL: The Experience of the AIEOP-BFM- ALL MRD Study Group

Integrin Alpha M Chain Expression at Diagnosis Is Inversely Correlated with Cytoreduction Rate and Is Consistently Up-Regulated during Therapy in Acute Lymphoblastic Leukemia (ALL)

Intact apoptosis signaling in myeloid leukemia cells determines treatment outcome in childhood AML

CD11b Is a Therapy-Induced Marker for Monitoring Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia.

Significance of Copy Number Alterations for Molecular Treatment Response in Childhood Acute Lymphoblastic Leukemia.

Favourable Treatment Outcome in Childhood AML Is Determined by Intact Apoptosis Signalling in Myeloid Leukaemia Cells.

Glucocorticoid Therapy Targets Proliferation, Differentiation and Bcl-2 Dependent Survival Signaling in ALL Blasts.

Cytochrome c–related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL

Gene Expression in Leukemic Blasts Persisting at Day 8 of Induction Therapy in Childhood ALL Displays a Common Shift towards Terminally Differentiated B Cells and a Cytoreduction-Associated Impairment of the Translational Machinery.

Stress-induced activation of the p53 tumor suppressor in leukemia cells and normal lymphocytes requires mitochondrial activity and reactive oxygen species

Differential Gene Expression in Leukemic Cells from Bone Marrow (BM) and Peripheral Blood (PB) of Pediatric Patients with Acute Lymphoblastic Leukemia (ALL).

Gene Expression Analysis of Leukemic Blasts Persisting at Day 8 of Induction Therapy in Childhood ALL.

High Expression Levels of Iaps Predict Poor Overall Survival in Childhood De Novo Acute Myeloid Leukemia.

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American Society of Hematology

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American Society of Hematology

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