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Journal Articles

Novel Mouse Model That Recapitulates the Hematologic Phenotype of Diamond Blackfan Anemia

Y. Lucy Liu, Nan Wang, Nicholas Neoman, Carolyn Wong, Bertil Glader, Raymond T. Doty, Mark C Wilkes, Janis L. Abkowitz, Kathleen M. Sakamoto

Blood (2023) 142 (Supplement 1): 944.

https://doi.org/10.1182/blood-2023-187734

Published: 2023

Journal Articles

Small Molecule Inhibitor Targeting Nemo-like Kinase Improves Erythropoiesis in Human and Mouse Models of Diamond Blackfan Anemia

Aya Shibuya, Lucy Liu, Mark C Wilkes, Nan Wang, Leonardo Daniels, Jayla Taylor, Bertil Glader, Kathleen M. Sakamoto

Blood (2023) 142 (Supplement 1): 2728.

https://doi.org/10.1182/blood-2023-182445

Published: 2023

Journal Articles

Novel Humanized Loss-of-Function NF1 Mouse Model of Juvenile Myelomonocytic Leukemia

Roshani Sinha, Rachana Patil, Rosa Romano, Esmond Lee, Zhenyu Yao, Y. Lucy Liu, Matthew H. Porteus, Alice Bertaina

Blood (2022) 140 (Supplement 1): 9765–9766.

https://doi.org/10.1182/blood-2022-167413

Published: 2022

Journal Articles

Combinatorial Cytokine Secretion Signature of Donor-Derived T Cells Infused with the Graft: A New Potential Biomarker of Acute Graft-Versus-Host Disease in Αβt-Cell/CD19 B-Cell Depleted Hematopoietic Stem Cell Transplant Recipients

Raul Montiel-Esparza, Giulia Barbarito, Samantha Peck, Magali Bazzano, Rachana Patil, David C. Shyr, Gopin Saini, Robertson Parkman, Y. Lucy Liu, Alice Bertaina

Blood (2021) 138 (Supplement 1): 1684.

https://doi.org/10.1182/blood-2021-149948

Published: 2021

Journal Articles

Aberrant Histone Landscape in Juvenile Myelomonocytic Leukemia

Roshani Sinha, Mai Dvorak, Charlotte M. Niemeyer, Kathleen M. Sakamoto, Rachana Patil, Paul J Utz, Y. Lucy Liu, Alex Kuo, Alice Bertaina

Blood (2021) 138 (Supplement 1): 4328.

https://doi.org/10.1182/blood-2021-152074

Published: 2021

Journal Articles

MLN0128, a Potential Target Therapy for Myeloid Proliferation Neoplasia (MPN) with a Benefit of Prolonging Survival

Rachana Patil, Nitza Vara, Peter D. Emanuel, Alice Bertaina, Y. Lucy Liu

Blood (2021) 138 (Supplement 1): 1464.

https://doi.org/10.1182/blood-2021-151976

Published: 2021

Journal Articles

Comparison of Fixed Vs ALC-Based Doses of Thymoglobulin ® (ATG) in Pediatric Patients with Acute Leukemia Given αβhaplo-HSCT: Impact on Immune Reconstitution at Day 90

Giulia Barbarito, David C Shyr, MD, Gopin Saini, MBBS, Linda Oppizzi, BS, Y. Lucy Liu, MDPhD, Rachana Patil, MS, Jaap-Jan Boelens, MD PhD, Alice Bertaina, MD PhD

Blood (2020) 136 (Supplement 1): 16.

https://doi.org/10.1182/blood-2020-140461

Published: 2020

Journal Articles

Exposure-Response Relationship of the Bruton Tyrosine Kinase Inhibitor, Zanubrutinib (BGB-3111) in Patients with Hematologic Malignancies

Ying Ou, PhD, Kun Wang, PhD, Lucy Liu, MBA, Ashutosh Jindal, BS, Yuying Gao, PhD, Sri Sahasranaman, PhD

Blood (2019) 134 (Supplement_1): 5063.

https://doi.org/10.1182/blood-2019-129580

Published: 2019

Journal Articles

CTX-8573, an Innate-Cell Engager Targeting BCMA, is a Highly Potent Multispecific Antibody for the Treatment of Multiple Myeloma

Blood (2019) 134 (Supplement_1): 3182.

https://doi.org/10.1182/blood-2019-128749

Published: 2019

Journal Articles

The Dosage of Pten Is Critical in Determining the Disease Severity - a Mouse Model Differentially Mimicking JMML and CMML

Yan Yan, MD, Natalia C Colorado, MD, Shelly Lensing, MS, Delli R Robinson, Nicholas J Baltz, Daohong Zhou, MD, Peter Dean Emanuel, MD, Y. Lucy Liu, MD PhD

Blood (2016) 128 (22): 1550.

https://doi.org/10.1182/blood.V128.22.1550.1550

Published: 2016

Journal Articles

JQ1, a Potential Therapeutic Molecule for Myeloid Leukemia with PTEN Deficiency

Nicholas J Baltz, Natalia C Colorado, MD, Yan Yan, MD, Shelly Lensing, MS, Delli Robinson, BA, Michele H. Cottler-Fox, MD, Jason E Farrar, MD, Peter Dean Emanuel, MD, Y. Lucy Liu, MD PhD

Blood (2016) 128 (22): 5899.

https://doi.org/10.1182/blood.V128.22.5899.5899

Published: 2016

Journal Articles

Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy

Y. Lucy Liu, Yan Yan, Cody Webster, Lijian Shao, Shelly Y. Lensing, Hongyu Ni, Wei Feng, Natalia Colorado, Rupak Pathak, Zhifu Xiang, Martin Hauer-Jensen, Shaoguang Li, Daohong Zhou, Peter D. Emanuel

Blood (2016) 127 (15): 1912–1922.

https://doi.org/10.1182/blood-2015-05-646216

Published: 2016

Includes: Supplemental data

Journal Articles

Recombinant FIX/X-Bp from the Japanese Habu Snake Is a Universal Ligand for Purification of Highly Carboxylated Factor IX Variants and Factor X

Oblaise Mercury, BS, Lucy Liu, PhD, Ayman Ismail, PhD, Ming Zhang, PhD, Qi Lu, PhD, Tom O Cameron, PhD, Allison Goodman, BS, Liz Culyba, PhD, Rahul Ravindran Nair, BS, MS, Amy M Holthaus, BS, MS, John Kulman, PhD, Robert Peters, PhD

Blood (2015) 126 (23): 1081.

https://doi.org/10.1182/blood.V126.23.1081.1081

Published: 2015

Journal Articles

Identification of Active Coagulation Factor IX Variants with Insertion or Fusion of Unstructured Polypeptide Xten

Zhiqian Lucy Liu, PhD, Arjan van der Flier, PhD, Sara Bardan, Sheng Ding, Volker Schellenberger, PhD, John Kulman, PhD, Robert Peters, PhD

Blood (2015) 126 (23): 2280.

https://doi.org/10.1182/blood.V126.23.2280.2280

Published: 2015

Journal Articles

Prolonged Half-Life and Improved Recovery of Recombinant Factor IX-XTEN Fusion Proteins in Hemophilia B Mouse Model

Arjan van der Flier, PhD, Zhiqian Lucy Liu, PhD, Zhan Liu, MSc, Oblaise Mercury, BS, Ayman Ismail, PhD, Ekta Seth-Chhabra, PhD, John Kulman, PhD, Volker Schellenberger, PhD, David R. Light, PhD, Robert Peters, PhD

Blood (2015) 126 (23): 2271.

https://doi.org/10.1182/blood.V126.23.2271.2271

Published: 2015

Journal Articles

Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia

Elliot Stieglitz, Camille B. Troup, Laura C. Gelston, John Haliburton, Eric D. Chow, Kristie B. Yu, Jon Akutagawa, Amaro N. Taylor-Weiner, Y. Lucy Liu, Yong-Dong Wang, Kyle Beckman, Peter D. Emanuel, Benjamin S. Braun, Adam Abate, Robert B. Gerbing, Todd A. Alonzo, Mignon L. Loh

Blood (2015) 125 (3): 516–524.

https://doi.org/10.1182/blood-2014-09-601690

Published: 2015

Includes: Supplemental data

Journal Articles

Opposite Effects of M1 and M2 Macrophages on Hematopoietic Stem Cell Self-Renewal and Ex Vivo Expansion

Yi Luo, MD PhD, Lijian Shao, MD PhD, Jianhui Chang, MS, Wei Feng, MD, Chengcheng Li, PhDcandidate, Y. Lucy Liu, MD PhD, Michele Cottler-Fox, MD, Peter D Emanuel, MD, Peter Murray, PhD, Daohong Zhou, MD

Blood (2014) 124 (21): 2909.

https://doi.org/10.1182/blood.V124.21.2909.2909

Published: 2014

Journal Articles

Timing of the Loss of Pten Is Critical in Determining the Disease Phenotype in Mice- a Mouse Model for Pediatric Mixed MDS/MPN

Y. Lucy Liu, MD PhD, Yan Yan, MD, Cody Webster, BS, Lijian Shao, MD PhD, Shelly Y. Lensing, MS, Hongyu Ni, MD PhD, Wei Feng, MD, Daohong Zhou, MD, Zhifu Xiang, MD, Natalia Colorado, MD, Delli Robinson, Shaoguang Li, MD PhD, Peter D Emanuel, MD

Blood (2014) 124 (21): 3585.

https://doi.org/10.1182/blood.V124.21.3585.3585

Published: 2014

Journal Articles

Assessing Structure-Activity Relationships in FVIII By Integration of Structural, Biophysical, and Biochemical Data Obtained with Anti-FVIII Antibodies

Zhiqian Lucy Liu, PhD, George Bou-Assaf, PhD, Ming Zhang, PhD, Allison Goodman, Po-lin Chiu, PhD, Melissa Chambers, Thomas Walz, PhD, Robert Peters, PhD, John Kulman, PhD

Blood (2014) 124 (21): 4223.

https://doi.org/10.1182/blood.V124.21.4223.4223

Published: 2014

Journal Articles

Subclonal Mutations in SETBP1 Predict Relapse in Juvenile Myelomonocytic Leukemia

Elliot Stieglitz, MD, Camille B Troup, PhD, Laura C Gelston, ScM, Eric D Chow, PhD, Kristie B Yu, Jon Akutagawa, BS, Amaro N Taylor-Weiner, BS, Y. Lucy Liu, MD PhD, Peter D Emanuel, MD, Benjamin S Braun, MD PhD, Robert B. Gerbing, MA, Todd A. Alonzo, PhD, Mignon L. Loh, MD

Blood (2014) 124 (21): 410.

https://doi.org/10.1182/blood.V124.21.410.410

Published: 2014

NARROW

Novel Mouse Model That Recapitulates the Hematologic Phenotype of Diamond Blackfan Anemia

Small Molecule Inhibitor Targeting Nemo-like Kinase Improves Erythropoiesis in Human and Mouse Models of Diamond Blackfan Anemia

Novel Humanized Loss-of-Function NF1 Mouse Model of Juvenile Myelomonocytic Leukemia

Combinatorial Cytokine Secretion Signature of Donor-Derived T Cells Infused with the Graft: A New Potential Biomarker of Acute Graft-Versus-Host Disease in Αβt-Cell/CD19 B-Cell Depleted Hematopoietic Stem Cell Transplant Recipients

Aberrant Histone Landscape in Juvenile Myelomonocytic Leukemia

MLN0128, a Potential Target Therapy for Myeloid Proliferation Neoplasia (MPN) with a Benefit of Prolonging Survival

Comparison of Fixed Vs ALC-Based Doses of Thymoglobulin ® (ATG) in Pediatric Patients with Acute Leukemia Given αβhaplo-HSCT: Impact on Immune Reconstitution at Day 90

Exposure-Response Relationship of the Bruton Tyrosine Kinase Inhibitor, Zanubrutinib (BGB-3111) in Patients with Hematologic Malignancies

CTX-8573, an Innate-Cell Engager Targeting BCMA, is a Highly Potent Multispecific Antibody for the Treatment of Multiple Myeloma

The Dosage of Pten Is Critical in Determining the Disease Severity - a Mouse Model Differentially Mimicking JMML and CMML

JQ1, a Potential Therapeutic Molecule for Myeloid Leukemia with PTEN Deficiency

Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy

Recombinant FIX/X-Bp from the Japanese Habu Snake Is a Universal Ligand for Purification of Highly Carboxylated Factor IX Variants and Factor X

Identification of Active Coagulation Factor IX Variants with Insertion or Fusion of Unstructured Polypeptide Xten

Prolonged Half-Life and Improved Recovery of Recombinant Factor IX-XTEN Fusion Proteins in Hemophilia B Mouse Model

Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia

Opposite Effects of M1 and M2 Macrophages on Hematopoietic Stem Cell Self-Renewal and Ex Vivo Expansion

Timing of the Loss of Pten Is Critical in Determining the Disease Phenotype in Mice- a Mouse Model for Pediatric Mixed MDS/MPN

Assessing Structure-Activity Relationships in FVIII By Integration of Structural, Biophysical, and Biochemical Data Obtained with Anti-FVIII Antibodies

Subclonal Mutations in SETBP1 Predict Relapse in Juvenile Myelomonocytic Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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