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    Luke Utley
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    Journal Articles

    Evaluation of Pharmacokinetic-Pharmacodynamic (PKPD) Relationship of an Oral, Selective, First-in-Class, Potent IDH2 Inhibitor, AG-221, from a Phase 1 Trial in Patients with Advanced IDH2 Mutant Positive Hematologic Malignancies

    Bin Fan, Yue Chen, Fang Wang, Katharine Yen, Luke Utley, Caroline Almon, Scott Biller, Sam Agresta, Hua Yang
    Journal: Blood
    Blood (2014) 124 (21): 3737.
    https://doi.org/10.1182/blood.V124.21.3737.3737
    Published: 2014
    Journal Articles

    Phase I Single (SAD) and Multiple Ascending Dose (MAD) Studies of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of AG-348, a First-in-Class Allosteric Activator of Pyruvate Kinase-R, in Healthy Subjects

    Hua Yang, Elizabeth Merica, Yue Chen, Marvin Cohen, Ronald Goldwater, Collin Hill, Hyeryun Kim, Penelope Kosinski, Charles Kung, Bruce Silver, Luke Utley, Sam Agresta
    Journal: Blood
    Blood (2014) 124 (21): 4007.
    https://doi.org/10.1182/blood.V124.21.4007.4007
    Published: 2014

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