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Manohursingh Runglall
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Journal Articles

Molecular, clinical, and therapeutic determinants of outcome in NPM1 -mutated AML

Clinical Trials & Observations
Jad Othman, Nicola Potter, Adam Ivey, Yanis Tazi, Elli Papaemmanuil, Jelena Jovanovic, Sylvie D. Freeman, Amanda Gilkes, Rosemary Gale, Tanya Rapoz-D’Silva, Manohursingh Runglall, Michelle Kleeman, Pawan Dhami, Ian Thomas, Sean Johnson, Joanna Canham, Jamie Cavenagh, Panagiotis Kottaridis, Claire Arnold, Hans Beier Ommen, Ulrik Malthe Overgaard, Mike Dennis, Alan Burnett, Charlotte Wilhelm-Benartzi, Brian Huntly, Nigel H. Russell, Richard Dillon
Journal: Blood
Blood (2024) 144 (7): 714–728.
https://doi.org/10.1182/blood.2024024310
Published: 2024
Includes: Supplemental data
Journal Articles

Postinduction molecular MRD identifies patients with NPM1 AML who benefit from allogeneic transplant in first remission

Clinical Trials & Observations Brief Report
Jad Othman, Nicola Potter, Adam Ivey, Jelena Jovanovic, Manohursingh Runglall, Sylvie D. Freeman, Amanda Gilkes, Ian Thomas, Sean Johnson, Joanna Canham, Jamie Cavenagh, Panagiotis Kottaridis, Claire Arnold, Hans Beier Ommen, Ulrik Malthe Overgaard, Mike Dennis, Alan Burnett, Charlotte Wilhelm-Benartzi, Richard Dillon, Nigel H. Russell
Journal: Blood
Blood (2024) 143 (19): 1931–1936.
https://doi.org/10.1182/blood.2023023096
Published: 2024
Includes: Supplemental data
Journal Articles

Pretransplant FLT3 -ITD MRD assessed by high-sensitivity PCR-NGS determines posttransplant clinical outcome

Sun Loo, Richard Dillon, Adam Ivey, Natasha S. Anstee, Jad Othman, Ing Soo Tiong, Nicola Potter, Jelena Jovanovic, Manohursingh Runglall, Chyn Chua Chong, Ashish Bajel, David Ritchie, Kelli Gray, Zhi Han Yeoh, Michelle McBean, Amanda Gilkes, Ian Thomas, Sean Johnson, Nigel H. Russell, Andrew H. Wei
Journal: Blood
Blood (2022) 140 (22): 2407–2411.
https://doi.org/10.1182/blood.2022016567
Published: 2022
Includes: Supplemental data
Journal Articles

High Sensitivity Detection of FLT3 -ITD Measurable Residual Disease By Deep Sequencing Prior to Hematopoietic Cell Transplant Is Highly Prognostic for Outcome in Acute Myeloid Leukemia

Sun Loo, Richard Dillon, Natasha S Anstee, Ing S Tiong, Adam Ivey, Nicola Potter, Jad Othman, Manohursingh Runglall, Jelena Jovanovic, Amanda Gilkes, Ian Thomas, Sean Johnson, Nigel H. Russell, Andrew H. Wei
Journal: Blood
Blood (2021) 138 (Supplement 1): 2364.
https://doi.org/10.1182/blood-2021-149301
Published: 2021
Journal Articles

Molecular MRD status and outcome after transplantation in NPM1 -mutated AML

Clinical Trials & Observations
Richard Dillon, Robert Hills, Sylvie Freeman, Nicola Potter, Jelena Jovanovic, Adam Ivey, Anju Shankar Kanda, Manohursingh Runglall, Nicola Foot, Mikel Valganon, Asim Khwaja, Jamie Cavenagh, Matthew Smith, Hans Beier Ommen, Ulrik Malthe Overgaard, Mike Dennis, Steven Knapper, Harpreet Kaur, David Taussig, Priyanka Mehta, Kavita Raj, Igor Novitzky-Basso, Emmanouil Nikolousis, Robert Danby, Pramila Krishnamurthy, Kate Hill, Damian Finnegan, Samah Alimam, Erin Hurst, Peter Johnson, Anjum Khan, Rahuman Salim, Charles Craddock, Ruth Spearing, Amanda Gilkes, Rosemary Gale, Alan Burnett, Nigel H. Russell, David Grimwade
Journal: Blood
Blood (2020) 135 (9): 680–688.
https://doi.org/10.1182/blood.2019002959
Published: 2020
Includes: Supplemental data
Journal Articles

Rapid Elimination of NPM1 Mutant Measurable Residual Disease (MRD) Using Low Intensity Venetoclax-Based Combinations in Acute Myeloid Leukemia (AML)

Ing S Tiong, MBChB,FRACP,FRCPA, Richard Dillon, MA, PhD MRCP, FRCPath, Adam Ivey, BSc, MSc, PhD, Tse-Chieh Teh, MBBS,PhDFRACP, FRCPA, Catherine Vassili, RN,MN, Vanessa Roma Donati, RN, David Taussig, PhD MRCP, FRCPath, Nicola Potter, PhD, Jelena Jovanovic, PhD, Anju Kanda, MSc, Manohursingh Runglall, MSc, Nicola Foot, MSc, Mikel Valganon, PhD, Nigel H. Russell, MD, Kavita Raj, MD PhD, Anthony P Schwarer, MD MBBS (Hons), FRACP, FRCPA, Chun Yew Fong, MBBS,PhDFRACP,FRCPA, Andrew Grigg, Steven Knapper, DM, Andrew H. Wei, PhD FRACP, FRCPA, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2648.
https://doi.org/10.1182/blood-2019-123899
Published: 2019
Journal Articles

Molecular MRD Monitoring Is Feasible in the Majority of Children with AML and Is Highly Predictive of Outcome: Results from the International MyeChild01 Study

Jelena Jovanovic, PhD, Nicola Potter, PhD, Anju Kanda, MSc, Claire Schwab, PhD, Aimee E Jackson, MSc, Richard Dillon, MA, PhD MRCP, FRCPath, Anna Lawson, BSc, Manohursingh Runglall, MSc, Paresh Vyas, MD PhD, Paul Virgo, Geoff Shenton, Nicholas Heaney, Beki James, MD, Katharine Patrick, MD, Persis J Amrolia, FRCP, FRCPath, PhD, Jean-Hugues Dalle, MD PhD, Gerard Michel, MD, Andrew S. Moore, MBBS,FRACP,PhD, Hélène Lapillonne, MD PhD, Claude Preudhomme, PharmD, PhD, Guy Leverger, MD, Owen P Smith, MD, Andre Baruchel, MD, Yves Bertrand, MD, Arnaud Petit, MD PhD, Keith Wheatley, DPhil, Pamela R. Kearns, PhDFRCPC, Christine J. Harrison, PhD FRCPath, Brenda Gibson, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1393.
https://doi.org/10.1182/blood-2019-125257
Published: 2019
Journal Articles

Pre-Transplant NPM1 Mutant Transcript Level Is Highly Predictive of Outcome after Allograft and Thresholds Are Dependent on FLT3 ITD Status

Richard Dillon, MA, PhD MRCP, FRCPath, Robert K. Hills, MA, DPhil, MSc, Sylvie D Freeman, MBChB, DPhil, Nicola Potter, PhD, Adam Ivey, BSc, MSc, PhD, Jelena Jovanovic, PhD, Anju Kanda, MSc, Manohursingh Runglall, MSc, Nicola Foot, MSc, Laura Upton, Asim Khwaja, MD PhD, Jamie Cavenagh, MD PhD, Ruth Spearing, MD, Alan K. Burnett, MD, Nigel H. Russell, David Grimwade, PhD MRCP, MRCPath
Journal: Blood
Blood (2018) 132 (Supplement 1): 2739.
https://doi.org/10.1182/blood-2018-99-113662
Published: 2018