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Journal Articles

Deep sequencing of the T-cell receptor repertoire in CD8 + T-large granular lymphocyte leukemia identifies signature landscapes

Michael J. Clemente, Bartlomiej Przychodzen, Andres Jerez, Brittney E. Dienes, Manuel G. Afable, Holleh Husseinzadeh, Hanna L. M. Rajala, Marcin W. Wlodarski, Satu Mustjoki, Jaroslaw P. Maciejewski

Blood (2013) 122 (25): 4077–4085.

https://doi.org/10.1182/blood-2013-05-506386

Published: 2013

Includes: Supplemental data

Journal Articles

Inhibition Of The JAK/STAT Signaling Pathway As a Novel Therapy In CD8+ T-Large Granular Lymphocyte Leukemia

Michael J. Clemente, Bilori Bilori, Swapna Thota, MD, Manuel G. Afable, II, Holleh D. Husseinzadeh, Alan E. Lichtin, Jaroslaw P. Maciejewski, MD, PhD

Blood (2013) 122 (21): 3902.

https://doi.org/10.1182/blood.V122.21.3902.3902

Published: 2013

Journal Articles

Association Of Large Granular Lymphocytic Leukemia (LGL) With B-Cell Lymphoproliferative Disorders

Alan P. Z. Skarbnik, MD, Craig A. Portell, MD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Ramon V. Tiu, MD, Brad Pohlman, MD, Manuel G. Afable, II, Anjali S. Advani, MD, Robert M Dean, MD, Brian T. Hill, MD, PhD, Leonard J. Horwitz, MD, Deepa Jagadeesh, MD, MPH, Alan E. Lichtin, Christy Samaras, DO, Mikkael A. Sekeres, MD, MS, Michael Millenson, MD, Mitchell R Smith, MD, PhD

Blood (2013) 122 (21): 1387.

https://doi.org/10.1182/blood.V122.21.1387.1387

Published: 2013

Journal Articles

LFA-3/CD2 Pathway, Potential Target For Immunosuppressive Therapy In Aplastic Anemia: A Phase I/II Trial Of Alefacept In Patients With Relapsed/Refractory Aplastic Anemia

Ramon V. Tiu, MD, Valeria Visconte, PhD, Paul Elson, Michael J. Clemente, Ali Tabarroki, MD, Edy Hasrouni, Amy Porter, Lindsey Mooney, Manuel G. Afable, II, Ricki Englehaupt, Joy Juersivich, RN, MSc, Kathleen Cooper, RN, MSc, Mikkael A. Sekeres, MD, MS, Yogen Saunthararajah, M.D., Jaroslaw P. Maciejewski, MD, PhD

Blood (2013) 122 (21): 3711.

https://doi.org/10.1182/blood.V122.21.3711.3711

Published: 2013

Journal Articles

Novel Pathogenic Defects Of Dead/H-Box Helicases In Myeloid Neoplasms

Blood (2013) 122 (21): 655.

https://doi.org/10.1182/blood.V122.21.655.655

Published: 2013

Journal Articles

Karyotypic and Genetic Abnormalities Associated with Clonal Evolution in Paroxysmal Nocturnal Hemoglobinuria.

Hideki Makishima, MD, PhD, Kenichi Yoshida, MD, Michael J. Clemente, Masashi Sanada, MD, Yasunobu Nagata, MD, Manuel G. Afable, II, MD, Andres Jerez, MD, Kenichi Chiba, BA, Yuichi Shiraishi, PhD, Satoru Miyano, PhD, Seishi Ogawa, MD, PhD, Jaroslaw P. Maciejewski, MD, PhD

Blood (2012) 120 (21): 2371.

https://doi.org/10.1182/blood.V120.21.2371.2371

Published: 2012

Journal Articles

Molecular Diversity Detected by Whole Exome Sequencing in Chronic Myelomonocytic Leukemia

Basel Rouphail, MD, Kenichi Yoshida, MD, Holleh D Husseinzadeh, MD;, Edward P Evans, Satoru Miyano, PhD, Yasunobu Nagata, MD, Yuichi Shiraishi, PhD, Kenichi Chiba, BA, Masashi Sanada, MD, Bartlomiej P Przychodzen, Ines Gomez-Segui, MD, Kathryn M Guinta, Manuel G. Afable, II, MD, Yogen Saunthararajah, MD, Mikkael A. Sekeres, MD, MS, Jaroslaw P. Maciejewski, MD, PhD, Seishi Ogawa, MD, PhD, Hideki Makishima, MD, PhD

Blood (2012) 120 (21): 310.

https://doi.org/10.1182/blood.V120.21.310.310

Published: 2012

Journal Articles

Whole Exome Sequencing to Predict Response to Hypomethylating Agents in MDS

Blood (2012) 120 (21): 1698.

https://doi.org/10.1182/blood.V120.21.1698.1698

Published: 2012

Journal Articles

Identification and Monitoring of Pathogenic T Cell Clones Using Deep TCR Sequencing in T-Large Granular Lymphocyte Leukemia and Aplastic Anemia

Michael J. Clemente, Bartlomiej Przychodzen, BS, Hideki Makishima, Manuel G. Afable, II, MD, Marcin W Wlodarski, Alan E. Lichtin, MD, Jaroslaw P. Maciejewski, MD, PhD

Blood (2012) 120 (21): 3477.

https://doi.org/10.1182/blood.V120.21.3477.3477

Published: 2012

Journal Articles

Identifying Immunogenetic Features That Distinguish Immune Mediated, Immunosuppression-Sensitive Disease in Aplastic Anemia (AA)

Manuel G. Afable, II, MD, Theresa Guo, MD, Bartlomiej P Przychodzen, Lisa Rybicki, MS, Michael J. Clemente, Andres Jerez, MD, PhD, Holleh D Husseinzadeh, MD;, Edward P Evans, Alan E. Lichtin, MD, Aleksandra Wodnar-Filipowicz, PhD, Mikkael A. Sekeres, MD, MS, Jaroslaw P. Maciejewski, MD, PhD

Blood (2012) 120 (21): 3481.

https://doi.org/10.1182/blood.V120.21.3481.3481

Published: 2012

Journal Articles

STAT3-Mutations Indicate the Presence of Subclinical Self-Reactive Cytotoxic T Cell Clones in Aplastic Anemia and Myelodysplastic Syndromes

Blood (2012) 120 (21): 646.

https://doi.org/10.1182/blood.V120.21.646.646

Published: 2012

Journal Articles

Anemia Associated with Increased IL-6 and IL-8 Levels Predicts for Worse Progression-Free Survival in T-Cell and NK-Cell Large Granular Lymphocyte (LGL) Leukemia but Is Improved by Treatment with Cyclophosphamide

Craig A. Portell, MD, Valeria Visconte, PhD, Michael J. Clemente, Manuel G. Afable, II, MD, Ali Tabarroki, MD, Fabiola Traina, MD, PhD, Yang Liu, Betty K. Hamilton, MD, Andres Jarez, Manoj Bupathi, MD, Leonard J. Horwitz, MD, Alan E. Lichtin, MD, Anjali Advani, MD, Mikkael A. Sekeres, MD, MS, Jaroslaw P. Maciejewski, MD, PhD, Ramon V. Tiu, MD

Blood (2012) 120 (21): 1261.

https://doi.org/10.1182/blood.V120.21.1261.1261

Published: 2012

Journal Articles

Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis

Hideki Makishima, Valeria Visconte, Hirotoshi Sakaguchi, Anna M. Jankowska, Sarah Abu Kar, Andres Jerez, Bartlomiej Przychodzen, Manoj Bupathi, Kathryn Guinta, Manuel G. Afable, Mikkael A. Sekeres, Richard A. Padgett, Ramon V. Tiu, Jaroslaw P. Maciejewski

Blood (2012) 119 (14): 3203–3210.

https://doi.org/10.1182/blood-2011-12-399774

Published: 2012

Includes: Supplemental data

Journal Articles

Distinction of Early and Late Molecular Events In Patients with Myelodysplastic Syndromes (MDS) Who Progressed to Acute Myeloid Leukemia (AML),

Manuel G Afable, II, MD, Hideki Makishima, MD, PhD, Hirotoshi Sakaguchi, MD, Andres Jerez, MD, Anna Malgorzata Jankowska, PhD, Kathryn M Guinta, Sara Abu Kar, MD, Fabiola Traina, MD, PhD, Yuka Sugimoto, MD, Christine O'Keefe, PhD, Ramon V. Tiu, MD, Mikkael A. Sekeres, MD, MS, Jaroslaw P Maciejewski, MD, PhD, FACP

Blood (2011) 118 (21): 3566.

https://doi.org/10.1182/blood.V118.21.3566.3566

Published: 2011

Journal Articles

T Cell Receptor Repertoire Landscape Mapping: A Novel Paradigm for T Cell Mediated Autoimmune Disorders Based on Deep Vβ Chain Sequencing

Michael J Clemente, Bartlomiej Przychodzen, Hideki Makishima, MD, PhD, Manuel G Afable, II, MD, Alan E. Lichtin, MD, Jaroslaw P. Maciejewski, MD, PhD

Blood (2011) 118 (21): 1341.

https://doi.org/10.1182/blood.V118.21.1341.1341

Published: 2011

Journal Articles

SNP array–based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes

Manuel G. Afable, II, Marcin Wlodarski, Hideki Makishima, Mohammed Shaik, Mikkael A. Sekeres, Ramon V. Tiu, Matt Kalaycio, Christine L. O'Keefe, Jaroslaw P. Maciejewski

Blood (2011) 117 (25): 6876–6884.

https://doi.org/10.1182/blood-2010-11-314393

Published: 2011

Includes: Supplemental data

NARROW

Deep sequencing of the T-cell receptor repertoire in CD8 + T-large granular lymphocyte leukemia identifies signature landscapes

Inhibition Of The JAK/STAT Signaling Pathway As a Novel Therapy In CD8+ T-Large Granular Lymphocyte Leukemia

Association Of Large Granular Lymphocytic Leukemia (LGL) With B-Cell Lymphoproliferative Disorders

LFA-3/CD2 Pathway, Potential Target For Immunosuppressive Therapy In Aplastic Anemia: A Phase I/II Trial Of Alefacept In Patients With Relapsed/Refractory Aplastic Anemia

Novel Pathogenic Defects Of Dead/H-Box Helicases In Myeloid Neoplasms

Karyotypic and Genetic Abnormalities Associated with Clonal Evolution in Paroxysmal Nocturnal Hemoglobinuria.

Molecular Diversity Detected by Whole Exome Sequencing in Chronic Myelomonocytic Leukemia

Whole Exome Sequencing to Predict Response to Hypomethylating Agents in MDS

Identification and Monitoring of Pathogenic T Cell Clones Using Deep TCR Sequencing in T-Large Granular Lymphocyte Leukemia and Aplastic Anemia

Identifying Immunogenetic Features That Distinguish Immune Mediated, Immunosuppression-Sensitive Disease in Aplastic Anemia (AA)

STAT3-Mutations Indicate the Presence of Subclinical Self-Reactive Cytotoxic T Cell Clones in Aplastic Anemia and Myelodysplastic Syndromes

Anemia Associated with Increased IL-6 and IL-8 Levels Predicts for Worse Progression-Free Survival in T-Cell and NK-Cell Large Granular Lymphocyte (LGL) Leukemia but Is Improved by Treatment with Cyclophosphamide

Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis

Distinction of Early and Late Molecular Events In Patients with Myelodysplastic Syndromes (MDS) Who Progressed to Acute Myeloid Leukemia (AML),

T Cell Receptor Repertoire Landscape Mapping: A Novel Paradigm for T Cell Mediated Autoimmune Disorders Based on Deep Vβ Chain Sequencing

SNP array–based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes

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