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Manuel L. Penichet
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Journal Articles

The Overexpression of Inactive Phosphorylated Raf-1 Kinase Inhibitory Protein (RKIP) in Multiple Myeloma (MM) Regulates the Resistance to Bortezomib-Induced Cytotoxicity: Reversal of Resistance by the PKC Inhibitor Bisindolylmalemide

Free
Sara Huerta-Yepez, PhD, Stavroula Baritaki, PhD, Hong Liu, Karla MC Mendez-Maldonado, B.S., Manuel L Penichet, M.D., Ph.D., Mario I Vega, PhD, Otoniel Martinez-Maza, PhD, Haiming Chen, James R. Berenson, MD, Devasis Chatterjee, PhD, Benjamin Bonavida, Ph.D
Journal: Blood
Blood (2011) 118 (21): 2892.
https://doi.org/10.1182/blood.V118.21.2892.2892
Published: 2011
Journal Articles

Targeting the Over-Expressed Transcription Factor Yin-Yang 1 (YY1) Sensitizes Resistant Multiple Myeloma (MM) Cell Lines to Apoptosis by Bortezomib or Melphalan,

Free
Hong Liu, Sara Huerta-Yepez, Ph.D, Clara M. Rivera-Pazos, MD, Ma de Lourdes Cabera-Muñoz, MD, Stavroula Baritaki, Ph.D, Suzie Vardanyan, Manuel L Penichet, M.D., Ph.D., Haiming Chen, James R. Berenson, MD, Benjamin Bonavida, Ph.D
Journal: Blood
Blood (2011) 118 (21): 3991.
https://doi.org/10.1182/blood.V118.21.3991.3991
Published: 2011
Journal Articles

Unique Pattern of Raf-1 Kinase Inhibitory Protein (RKIP) Expression in Multiple Myeloma (MM): RKIP Overexpression and RKIP Phosphorylation Is Common in MM Tumor Cells

Free
Stavroula Baritaki, Ph.D., Sara Huerta-Yepez, Ph.D., Ma de Lourdes Cabera-Muñoz, MD, Clara Rivera-Pazos, MD, Kam Yeung, Ph.D., Manuel L Penichet, M.D., Ph.D., Haiming Chen, MD, PhD, James R. Berenson, MD, Benjamin Bonavida, PhD
Journal: Blood
Blood (2008) 112 (11): 2729.
https://doi.org/10.1182/blood.V112.11.2729.2729
Published: 2008
Journal Articles

Inhibition of the Akt Pathway in MM Cell Lines by the Anti-TfR-IgG3-Avidin Fusion Protein (Anti-TfR-IgG3-Av): Role in Chemosensitization to CDDP-Induced Apoptosis

Free
Eriko Suzuki, Ph.D., Kazuo Umezawa, Ph.D., Gustavo Helguera, PhD, Tracy R Daniels, Ph.D., Gary Schiller, James R. Berenson, MD, Manuel L Penichet, M.D., Ph.D., Benjamin Bonavida, PhD
Journal: Blood
Blood (2008) 112 (11): 4473.
https://doi.org/10.1182/blood.V112.11.4473.4473
Published: 2008
Journal Articles

Cellular and Molecular Mechanisms of Sensitivity and Resistance of Hematopoietic Malignant Cells to Treatment with ch128.1Av, An Antibody-Avidin Fusion Protein Specific for Human Transferrin Receptor 1 (CD71).

Free
Jose A Rodriguez, Gustavo Helguera, PhD, Tracy R Daniels, Ph.D., David Casero Diaz-Cano, Ph.D., Elizabeth Ortiz-Sanchez, PhD, Giovanni Coppola, Ph.D., Matteo Pellegrini, Ph.D., Otoniel Martinez-Maza, Ph.D., Manuel L Penichet, M.D., Ph.D.
Journal: Blood
Blood (2008) 112 (11): 1608.
https://doi.org/10.1182/blood.V112.11.1608.1608
Published: 2008
Journal Articles

Identification of Differentially Expressed Genes in the Rituximab- Resistant Clone (Ramos RR1) Compared to Wildtype Sensitive Ramos: Therapeutic Implications in Rituximab-Resistance

Free
Stavroula Baritaki, PhD, Jose Rodriguez, Gustavo Helguera, PhD, Melisa Martinez-Paniagua, Mario Vega, PhD, Sara Huerta-Yepez, PhD., Ali Jazirehi, PhD, Demetrios Spandidos, PhD, Manuel L Penichet, M.D., Ph.D., Benjamin Bonavida, PhD
Journal: Blood
Blood (2008) 112 (11): 3770.
https://doi.org/10.1182/blood.V112.11.3770.3770
Published: 2008
Journal Articles

The Role of Iron in the Cytotoxicity Induced in Hematopoietic Malignant Cell Lines by an Anti-Transferrin Receptor IgG3-Avidin Fusion Protein and Gambogic Acid.

Free
Elizabeth Ortiz-Sanchez, PhD, Tracy R. Daniels, Ph.D., Gustavo Helguera, Ph.D., Otoniel Martinez-Maza, Ph.D., Benjamin Bonavida, Ph.D., Manuel L. Penichet, M.D., Ph.D.
Journal: Blood
Blood (2007) 110 (11): 4204.
https://doi.org/10.1182/blood.V110.11.4204.4204
Published: 2007
Journal Articles

Insights into the Genetic Signature Associated with Cell Death Induced by an Antibody-Avidin Fusion Protein Specific for Transferrin Receptor.

Free
Gustavo Helguera, PhD, Jose A. Rodriguez, Tracy R. Daniels, PhD, David Casero Diaz-Cano, PhD, Matteo Pellegrini, PhD, Manuel L. Penichet, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 3476.
https://doi.org/10.1182/blood.V110.11.3476.3476
Published: 2007
Journal Articles

Targeting aurora kinases as therapy in multiple myeloma

Free
Yijiang Shi, Tony Reiman, Weiqun Li, Christopher A. Maxwell, Subrata Sen, Linda Pilarski, Tracy R. Daniels, Manuel L. Penichet, Rick Feldman, Alan Lichtenstein
Journal: Blood
Blood (2007) 109 (9): 3915–3921.
https://doi.org/10.1182/blood-2006-07-037671
Published: 2007
Journal Articles

Molecular events contributing to cell death in malignant human hematopoietic cells elicited by an IgG3-avidin fusion protein targeting the transferrin receptor

Free
Patrick P. Ng, Gustavo Helguera, Tracy R. Daniels, Simon Z. Lomas, Jose A. Rodriguez, Gary Schiller, Benjamin Bonavida, Sherie L. Morrison, Manuel L. Penichet
Journal: Blood
Blood (2006) 108 (8): 2745–2754.
https://doi.org/10.1182/blood-2006-04-020263
Published: 2006
Includes: Supplemental data