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Journal Articles

Molecular mechanisms of leukocyte β2 integrin activation

Lai Wen, Markus Moser, Klaus Ley

Blood (2022) 139 (24): 3480–3492.

https://doi.org/10.1182/blood.2021013500

Published: 2022

Journal Articles

The integrin-linked kinase is required for chemokine-triggered high-affinity conformation of the neutrophil β 2 -integrin LFA-1

Andreas Margraf, Giulia Germena, Hannes C. A. Drexler, Jan Rossaint, Nadine Ludwig, Barbara Prystaj, Sina Mersmann, Katharina Thomas, Helena Block, Wiebke Gottschlich, Chang Liu, Peter W. Krenn, Hermann Haller, Barbara Heitplatz, Marika Meyer zu Brickwedde, Markus Moser, Dietmar Vestweber, Alexander Zarbock

Blood (2020) 136 (19): 2200–2205.

https://doi.org/10.1182/blood.2020004948

Published: 2020

Includes: Supplemental data

Journal Articles

Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps

Blood (2019) 134 (21): 1859–1872.

https://doi.org/10.1182/blood.2019000518

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Direct Rap1/Talin1 interaction regulates platelet and neutrophil integrin activity in mice

Thomas Bromberger, Sarah Klapproth, Ina Rohwedder, Liang Zhu, Laura Mittmann, Christoph A. Reichel, Markus Sperandio, Jun Qin, Markus Moser

Blood (2018) 132 (26): 2754–2762.

https://doi.org/10.1182/blood-2018-04-846766

Published: 2018

Includes: Supplemental data

Journal Articles

Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired β2 integrin function in mice

Sarah Klapproth, Markus Sperandio, Elaine M. Pinheiro, Monika Prünster, Oliver Soehnlein, Frank B. Gertler, Reinhard Fässler, Markus Moser

Blood (2015) 126 (25): 2704–2712.

https://doi.org/10.1182/blood-2015-05-647453

Published: 2015

Includes: Supplemental data

Journal Articles

Minimal amounts of kindlin-3 suffice for basal platelet and leukocyte functions in mice

Sarah Klapproth, Federico A. Moretti, Marlis Zeiler, Raphael Ruppert, Ute Breithaupt, Susanna Mueller, Rainer Haas, Matthias Mann, Markus Sperandio, Reinhard Fässler, Markus Moser

Blood (2015) 126 (24): 2592–2600.

https://doi.org/10.1182/blood-2015-04-639310

Published: 2015

Includes: Supplemental data

Journal Articles

The integrin coactivator Kindlin-3 is not required for lymphocyte diapedesis

Shmuel J. Cohen, Irina Gurevich, Sara W. Feigelson, Ekaterina Petrovich, Markus Moser, Guy Shakhar, Reinhard Fassler, Ronen Alon

Blood (2013) 122 (15): 2609–2617.

https://doi.org/10.1182/blood-2013-04-495036

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

β1 integrin−mediated signals are required for platelet granule secretion and hemostasis in mouse

Tobias Petzold, Raphael Ruppert, Dharmendra Pandey, Verena Barocke, Hannelore Meyer, Michael Lorenz, Lin Zhang, Wolfgang Siess, Steffen Massberg, Markus Moser

Blood (2013) 122 (15): 2723–2731.

https://doi.org/10.1182/blood-2013-06-508721

Published: 2013

Includes: Supplemental data

Journal Articles

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

Craig T. Lefort, Jan Rossaint, Markus Moser, Brian G. Petrich, Alexander Zarbock, Susan J. Monkley, David R. Critchley, Mark H. Ginsberg, Reinhard Fässler, Klaus Ley

Blood (2012) 119 (18): 4275–4282.

https://doi.org/10.1182/blood-2011-08-373118

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules

Stefanie Kliche, Tim Worbs, Xiaoqian Wang, Janine Degen, Irene Patzak, Bernhard Meineke, Mauro Togni, Markus Moser, Annegret Reinhold, Friedemann Kiefer, Christian Freund, Reinhold Förster, Burkhart Schraven

Blood (2012) 119 (3): 777–785.

https://doi.org/10.1182/blood-2011-06-362269

Published: 2012

Includes: Supplemental data

Journal Articles

RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo

David Frommhold, Anna Kamphues, Ingrid Hepper, Monika Pruenster, Ivan K. Lukić, Ines Socher, Victoria Zablotskaya, Kirsten Buschmann, Baerbel Lange-Sperandio, Jürgen Schymeinsky, Eduard Ryschich, Johannes Poeschl, Christian Kupatt, Peter P. Nawroth, Markus Moser, Barbara Walzog, Angelika Bierhaus, Markus Sperandio

Blood (2010) 116 (5): 841–849.

https://doi.org/10.1182/blood-2009-09-244293

Published: 2010

Includes: Multimedia, Supplemental data

Journal Articles

Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation

Pavel Uhrin, Jan Zaujec, Johannes M. Breuss, Damla Olcaydu, Peter Chrenek, Hannes Stockinger, Elke Fuertbauer, Markus Moser, Paula Haiko, Reinhard Fässler, Kari Alitalo, Bernd R. Binder, Dontscho Kerjaschki

Blood (2010) 115 (19): 3997–4005.

https://doi.org/10.1182/blood-2009-04-216069

Published: 2010

Includes: Supplemental data

Journal Articles

Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions

Eugenia Manevich-Mendelson, Sara W. Feigelson, Ronit Pasvolsky, Memet Aker, Valentin Grabovsky, Ziv Shulman, Sara Sebnem Kilic, Maria Alessandra Rosenthal-Allieri, Shifra Ben-Dor, Adi Mory, Alain Bernard, Markus Moser, Amos Etzioni, Ronen Alon

Blood (2009) 114 (11): 2344–2353.

https://doi.org/10.1182/blood-2009-04-218636

Published: 2009

Includes: Supplemental data

Journal Articles

LAD-1/variant syndrome is caused by mutations in FERMT3

Taco W. Kuijpers, Edith van de Vijver, Marian A. J. Weterman, Martin de Boer, Anton T. J. Tool, Timo K. van den Berg, Markus Moser, Marja E. Jakobs, Karl Seeger, Özden Sanal, Sule Ünal, Mualla Çetin, Dirk Roos, Arthur J. Verhoeven, Frank Baas

Blood (2009) 113 (19): 4740–4746.

https://doi.org/10.1182/blood-2008-10-182154

Published: 2009

Journal Articles

Molecular cloning and characterization of a human metalloprotease disintegrin— a novel marker for dendritic cell differentiation

Jana Fritsche, Markus Moser, Stefan Faust, Alice Peuker, Reinhard Büttner, Reinhard Andreesen, Marina Kreutz

Blood (2000) 96 (2): 732–739.

https://doi.org/10.1182/blood.V96.2.732

Published: 2000

NARROW

Molecular mechanisms of leukocyte β2 integrin activation

The integrin-linked kinase is required for chemokine-triggered high-affinity conformation of the neutrophil β 2 -integrin LFA-1

Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps

Direct Rap1/Talin1 interaction regulates platelet and neutrophil integrin activity in mice

Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired β2 integrin function in mice

Minimal amounts of kindlin-3 suffice for basal platelet and leukocyte functions in mice

The integrin coactivator Kindlin-3 is not required for lymphocyte diapedesis

β1 integrin−mediated signals are required for platelet granule secretion and hemostasis in mouse

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules

RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo

Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation

Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions

LAD-1/variant syndrome is caused by mutations in FERMT3

Molecular cloning and characterization of a human metalloprotease disintegrin— a novel marker for dendritic cell differentiation

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American Society of Hematology

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American Society of Hematology

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