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Journal Articles

RAC1 Inhibitor EHT1864 and Venetoclax Overcome Midostaurin Resistance in Acute Myeloid Leukemia

Blood (2019) 134 (Supplement_1): 1277.

https://doi.org/10.1182/blood-2019-129762

Published: 2019

Journal Articles

Clonal Competition Models to Understand Progression and Resistance in Myeloma

Santiago Barrio, PhD, Larissa Haertle, PhD, Umair Munawar, MSc, Lucia Martin, Isabel Cuenca, MSc, Cornelia Vogt, MSc, Andoni Garitano-Trojaola, PhD, Matteo Claudio Da Via', MD, Miguel Gallardo, PhD, Thorsten Stuehmer, PhD, Hermann Einsele, MD, Leo Rasche, MD, Joaquin Martinez-Lopez, MD PhD, Martin Kortüm, MD

Blood (2019) 134 (Supplement_1): 1807.

https://doi.org/10.1182/blood-2019-130812

Published: 2019

Journal Articles

Mechanisms of Proteasome Inhibitor Resistance Selected By Clonal Evolution in Multiple Myeloma

Larissa Haertle, PhD, Santiago Barrio, PhD, Michal Simicek, PhD, Umair Munawar, MSc, Ricardo Sanchez, PhD MD, Max Bittrich, MD, Matteo DaVia, MD, Cornelia Vogt, MSc, Nicola Giesen, MD, Andoni Garitano-Trojaola, PhD, Silvia Nerreter, Thorsten Stuehmer, PhD, Marc S. Raab, MD, Joaquin Martinez Lopez, MD PhD, Roman Hajek, MD, Hermann Einsele, MD, Leo Rasche, MD, Thomas Haaf, MD, Martin Kortüm, MD

Blood (2019) 134 (Supplement_1): 4349.

https://doi.org/10.1182/blood-2019-130847

Published: 2019

Journal Articles

CIC-Mutation As a Potential Molecular Mechanism of Acquired Resistance to Combined BRAF/MEK Inhibition in CNS Multiple Myeloma

Matteo Claudio Da Via', MD, Antonio Giovanni Solimando, MD, Andoni Garitano-Trojaola, PhD, Santiago Barrio, PhD, Nadine Rodhes, Susanne Strifler, MD, Eva Teufel, Constantin Lapa, MD, Hermann Einsele, MD, Andreas Beilhack, MD, K. Martin Kortüm, MD

Blood (2018) 132 (Supplement 1): 3181.

https://doi.org/10.1182/blood-2018-99-117203

Published: 2018

Journal Articles

Minimal Residual Disease (MRD) Analysis Using Multiparametric Flow Cytometry (MFC) and Identification of Differences in Subpopulations Using Next Generation Sequencing (NGS) in the Bone Marrow (BM) of Multiple Myeloma (MM) Patients (pts)

Sandra M. Dold, MSc, BSc, Veronika Riebl, Dagmar Wider, Marie Follo, PhD, Stefan J. Mueller, Ingrid Bartsch, Milena Pantic, PhD, Cornelius Miething, MD, Chrissoula Kiote-Schmidt, K. Martin Kortüm, MD, Mihaela Zlei, Abdel Kareem Azab, PhD, Mascha Binder, MD, Justyna Rawluk, Justus Duyster, Prof., Robert Zeiser, MD, Ralph Wäsch, MD, Monika Engelhardt, MD

Blood (2018) 132 (Supplement 1): 3222.

https://doi.org/10.1182/blood-2018-99-112489

Published: 2018

Journal Articles

Focusing PI and IMiD Resistance in Multiple Myeloma: Impact of DNA Methylation

Larissa Haertle, PhD, Max Bittrich, MD, Ramya Potabattula, PhD, Matteo Claudio Da Via', MD, Umair Munawar, MS, BS, Yanira Ruiz-Heredia, Cornelia Vogt, Torsten Steinbrunn, Andoni Garitano-Trojaola, PhD, Thorsten Stuehmer, Joaquin Martinez Lopez, MD PhD, Hermann Einsele, MD, Thomas Haaf, MD PhD, K. Martin Kortüm, MD, Santiago Barrio Garcia, PhD

Blood (2018) 132 (Supplement 1): 404.

https://doi.org/10.1182/blood-2018-99-118944

Published: 2018

Journal Articles

The HACE1-NRF2 Axis a Novel Target in Acute Myeloid Leukemia

Andoni Garitano-Trojaola, PhD, Eva Teufel, Nadine Rodhes, Jennifer Kreckel, Thorsten Stuehmer, Matteo Claudio Da Via', MD, Santiago Barrio Garcia, PhD, Torsten Haferlach, MD, Raoul Tibes, Harald Wajant, Andreas Rosenwald, Hermann Einsele, MD, K. Martin Kortüm, MD

Blood (2018) 132 (Supplement 1): 5132.

https://doi.org/10.1182/blood-2018-99-118270

Published: 2018

Journal Articles

The Role of NRAS G12D Mutations in the Response to Conventional Chemotherapy and 5-Azacitidine in Secondary AML

Andoni Garitano-Trojaola, PhD, Eva Teufel, Matteo Claudio Da Via', MD, Ana Sancho, Nadine Rodhes, Thorsten Stuehmer, Santiago Barrio Garcia, PhD, Jürgen Groll, Torsten Haferlach, MD, Raoul Tibes, Andreas Rosenwald, Hermann Einsele, MD, Martin Kortüm, MD

Blood (2018) 132 (Supplement 1): 5148.

https://doi.org/10.1182/blood-2018-99-118484

Published: 2018

Journal Articles

Central Function for JAM-a in Multiple Myeloma Patients with Extramedullary Disease

Blood (2018) 132 (Supplement 1): 4455.

https://doi.org/10.1182/blood-2018-99-117021

Published: 2018

Journal Articles

Molecular Resistance Mechanisms in Multiple Myeloma

Santiago Barrio Garcia, PhD, Umair Munawar, MS, BS, Thorsten Stuehmer, Hermann Einsele, MD, K. Martin Kortüm, MD

Blood (2018) 132 (Supplement 1): 471.

https://doi.org/10.1182/blood-2018-99-118700

Published: 2018

Journal Articles

Implications of TP53 alterations for Therapy Response in Multiple Myeloma

Umair Munawar, MS, BS, Santiago Barrio, PhD, Markus Roth, Hermann Einsele, MD, Ralf C Bargou, Thorsten Stuehmer, Martin Kortum, MD

Blood (2018) 132 (Supplement 1): 3189.

https://doi.org/10.1182/blood-2018-99-118658

Published: 2018

Journal Articles

MET-PET and NGS Targeted Sequencing Guides Precision Medicine in a CNS Relapsed MM Patient

Matteo Da Via', MD, Susanne Strifler, MD, Santiago Barrio Garcia, PhD, Andoni Garitano Trojaola, PhD, Eva Teufel, Silvia Nerreter, A. Keith Stewart, MBChB, MBA, Andreas Rosenwald, Anke Heidemeier, MD, Constantin Lapa, MD, Hermann Einsele, K. Martin Kortüm, MD

Blood (2017) 130 (Supplement 1): 5361.

https://doi.org/10.1182/blood.V130.Suppl_1.5361.5361

Published: 2017

Journal Articles

A Whole Blood Gene Expression Signature Accurately Diagnoses Multiple Myeloma and Differentiates Patients in Remission from Those with Active and Progressive Disease

Martin Schreder, MD, Santiago Barrio Garcia, PhD, Ignat Drozdov, Ken Herrmann, MDPhD, Hermann Einsele, Mark Kidd, PhDDABCC, Irvin M Modlin, MDPhDDSc, K. Martin Kortüm, MD

Blood (2017) 130 (Supplement 1): 4344.

https://doi.org/10.1182/blood.V130.Suppl_1.4344.4344

Published: 2017

Journal Articles

Role of MAX As a Tumor Suppressor Driver Gene in Multiple Myeloma

Santiago Barrio Garcia, PhD, Yanira Ruiz-Heredia, Matteo Da Via', MD, Miguel Gallardo, PhD, Andoni Garitano-Trojaola, PhD, Josip Zovko, MD, Marc S Raab, MD PhD, Pieter Sonneveld, MDPhD, Esteban Braggio, PhD, A. Keith Stewart, MBChB, MBA, Hermann Einsele, Joaquín Martínez, K. Martin Kortüm, MD

Blood (2017) 130 (Supplement 1): 4347.

https://doi.org/10.1182/blood.V130.Suppl_1.4347.4347

Published: 2017

Journal Articles

IKZF1/3 and CRL4 CRBN E3 Ubiquitin Ligase Mutations Associate with IMiD Resistance in Relapsed Multiple Myeloma

Santiago Barrio Garcia, PhD, Matteo Da Via', MD, Andoni Garitano-Trojaola, PhD, Yanira Ruiz-Heredia, Max Bittrich, MD, ChangXin Shi, PhD, Yuan Zhu, Nicola Lehners, MD, Elias K Mai, MD, Marc S Raab, MD PhD, Pieter Sonneveld, MDPhD, Joaquín Martínez, Andreas Rosenwald, Esteban Braggio, PhD, Hermann Einsele, A. Keith Stewart, MBChB, MBA, K. Martin Kortüm, MD

Blood (2017) 130 (Supplement 1): 270.

https://doi.org/10.1182/blood.V130.Suppl_1.270.270

Published: 2017

Journal Articles

Parallel Evolution of Multiple PSMB5 mutations in a Myeloma Patient Treated with Bortezomib

Santiago Barrio, PhD, Thorsten Stühmer, PhD, Eva Teufel, Clara Barrio-Garcia, Manik Chatterjee, MD, Martin Schreder, MD, Mithun Das Gupta, MD, Andreas Rosenwald, MD, Raoul Tibes, MD PhD, Esteban Braggio, PhD, A. Keith Stewart, MD, Ralf C Bargou, MD, Hermann Einsele, MD, K Martin Kortüm, MD

Blood (2016) 128 (22): 3282.

https://doi.org/10.1182/blood.V128.22.3282.3282

Published: 2016

Journal Articles

Complementary Activation of Ccnd, MYC, RAS and NFkB By Mutations in Multiple Myeloma

Kristine Misund, PhD, Niamh Keane, MD, Yan W Asmann, PhD, Scott Van Wier, Daniel Riggs, PhD, Gregory Ahmann, Marta Chesi, PhD, K. Martin Körtum, MD, Rafael Fonseca, MD, A. Keith Stewart, MD, Esteban Braggio, PhD, P. Leif Bergsagel, MD

Blood (2016) 128 (22): 355.

https://doi.org/10.1182/blood.V128.22.355.355

Published: 2016

Journal Articles

M3P Sequencing Panel Identifies TP53 Mutational Status As a Prognostic Factor in Chemotherapy-Naive Multiple Myeloma

Davine Hofste op Bruinink, MD MSc, K. Martin Kortüm, MD, Mark van Duin, PhD, Mathijs A. Sanders, PhD, Remco Hoogenboezem, MSc, Michael Vermeulen, BSc, Laura Bruins, Jonathan Ahmann, Annemiek Broijl, MD PhD, Sonja Zweegman, MD PhD, Esteban Braggio, PhD, Bronno van der Holt, PhD, A. Keith Stewart, MD PhD, Pieter Sonneveld, MD PhD

Blood (2015) 126 (23): 2984.

https://doi.org/10.1182/blood.V126.23.2984.2984

Published: 2015

Journal Articles

Bone Marrow Interaction and Multiple Myeloma - Approximating Reality in Novel High-Throughput Multiple Myeloma Coculture Systems

Johannes Waldschmidt, MD, Dagmar Wider, Anna Simon, Andreas R. Thomsen, MD, Christine Aldrian, Marie Follo, PhD, Julia Schüler, Martin Kortum, MD, Ralph Wäsch, MD, Monika Engelhardt, MD

Blood (2014) 124 (21): 2243.

https://doi.org/10.1182/blood.V124.21.2243.2243

Published: 2014

NARROW

RAC1 Inhibitor EHT1864 and Venetoclax Overcome Midostaurin Resistance in Acute Myeloid Leukemia

Clonal Competition Models to Understand Progression and Resistance in Myeloma

Mechanisms of Proteasome Inhibitor Resistance Selected By Clonal Evolution in Multiple Myeloma

CIC-Mutation As a Potential Molecular Mechanism of Acquired Resistance to Combined BRAF/MEK Inhibition in CNS Multiple Myeloma

Minimal Residual Disease (MRD) Analysis Using Multiparametric Flow Cytometry (MFC) and Identification of Differences in Subpopulations Using Next Generation Sequencing (NGS) in the Bone Marrow (BM) of Multiple Myeloma (MM) Patients (pts)

Focusing PI and IMiD Resistance in Multiple Myeloma: Impact of DNA Methylation

The HACE1-NRF2 Axis a Novel Target in Acute Myeloid Leukemia

The Role of NRAS G12D Mutations in the Response to Conventional Chemotherapy and 5-Azacitidine in Secondary AML

Central Function for JAM-a in Multiple Myeloma Patients with Extramedullary Disease

Molecular Resistance Mechanisms in Multiple Myeloma

Implications of TP53 alterations for Therapy Response in Multiple Myeloma

MET-PET and NGS Targeted Sequencing Guides Precision Medicine in a CNS Relapsed MM Patient

A Whole Blood Gene Expression Signature Accurately Diagnoses Multiple Myeloma and Differentiates Patients in Remission from Those with Active and Progressive Disease

Role of MAX As a Tumor Suppressor Driver Gene in Multiple Myeloma

IKZF1/3 and CRL4 CRBN E3 Ubiquitin Ligase Mutations Associate with IMiD Resistance in Relapsed Multiple Myeloma

Parallel Evolution of Multiple PSMB5 mutations in a Myeloma Patient Treated with Bortezomib

Complementary Activation of Ccnd, MYC, RAS and NFkB By Mutations in Multiple Myeloma

M3P Sequencing Panel Identifies TP53 Mutational Status As a Prognostic Factor in Chemotherapy-Naive Multiple Myeloma

Bone Marrow Interaction and Multiple Myeloma - Approximating Reality in Novel High-Throughput Multiple Myeloma Coculture Systems

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American Society of Hematology

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American Society of Hematology

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