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Mathias Hänel, MD
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Journal Articles

Azacitidine for Pre-Emptive Treatment of Measurable-Residual Disease in MDS/AML Patients at High Risk of Hematological Relapse: Results of the Second Cohort of the RELAZA2 Trial

Uwe Platzbecker, MD, Jan Moritz Middeke, MD, Katja Sockel, MD, Regina Herbst, MD, Lars R. Fransecky, MD, Dominik Wolf, MD, Schumacher Martin, MD, Alwin Krämer, MD, Richard Noppeney, MD, Juergen Novotny, MD, Gesine Bug, Katharina Götze, Karsten Spiekermann, MD, Matthias Stelljes, MD, Christoph Groth, MD, Marion Subklewe, MD, Antje Schubert, Anke Mütherig, MD, Tilmann Bochtler, MD, Marika Mende, MD, Anne Sophie Kubasch, MD, Mathias Hänel, MD, Ulrich Dührsen, Prof, MD PhD, Johannes Schetelig, MD MSc, Christoph Röllig, MD MSC, Claudia D Baldus, Gerhard Ehninger, MD, Carsten Müller-Tidow, MD, Hubert Serve, MD, Michael Kramer, M.Sc., Martin Bornhäuser, MD, Christian Thiede, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 644.
https://doi.org/10.1182/blood-2019-129926
Published: 2019
Journal Articles

Time from Diagnosis to Treatment Does Not Affect Outcome in Intensively Treated Patients with Newly Diagnosed Acute Myeloid Leukemia

Christoph Röllig, MD MSC, Michael Kramer, M.Sc., Christoph Schliemann, Jan-Henrik Mikesch, MD, Björn Steffen, MD, Alwin Krämer, MD, Tim Sauer, MD, Mathias Hänel, MD, Regina Herbst, MD, Kerstin Schäfer-Eckart, MD, Richard Noppeney, MD, Edgar Jost, MD, Tim H Brümmendorf, MD, Stefan W Krause, MD, Volker Kunzmann, MD PhD, Hermann Einsele, MD, Sebastian Scholl, Andreas Hochhaus, MD, Lars R. Fransecky, MD, Martin Kaufmann, MD, Andreas Neubauer, MD, Dirk Niemann, MD, Markus Schaich, MD, Norbert Frickhofen, MD, Alexander Kiani, Frank Heits, MD, Ulrich Krümpelmann, Ulrich Kaiser, MD, Johannes Kullmer, Maxi Wass, MD, Stefan Klein, MD, Malte Von Bonin, Jan Moritz Middeke, MD, Christian Thiede, MD, Friedrich Stoelzel, MD, Johannes Schetelig, MDMSc, Gerhard Ehninger, MD, Claudia D Baldus, Carsten Müller-Tidow, MD, Uwe Platzbecker, Hubert Serve, MD, Martin Bornhäuser, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 13.
https://doi.org/10.1182/blood-2019-123717
Published: 2019
Journal Articles

Conventional Immunochemotherapy (R-CHOEP) Vs High-Dose Immunochemotherapy (R-MegaCHOEP) in Younger Patients with High-Risk Aggressive B-Cell Lymphoma: 10-Year Long-Term Follow-up of a German Lymphoma Alliance (GLA) Study

Fabian Frontzek, MD, Marita Ziepert, PhD, Maike Nickelsen, Bettina Altmann, PhD, Bertram Glass, Mathias Hänel, MD, Lorenz Truemper, MD, Gerhard Held, MD, Martin Bentz, MD, Peter Borchmann, MD, Martin H. Dreyling, MD PhD, Andreas Viardot, MD PhD, Frank P. Kroschinsky, MDMBA, Bernd Metzner, MD PhD, Annette M. Staiger, PhD, Heike Horn, PhD, German Ott, MD, Andreas Rosenwald, MD, Markus Loeffler, MD, Georg Lenz, MD, Norbert Schmitz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1589.
https://doi.org/10.1182/blood-2019-123637
Published: 2019
Journal Articles

Impact of Somatic Mutations on Outcome in Patients > 60 Years Old with Newly Diagnosed AML Treated with Response-Adapted Sequential Azacitidine and Induction Chemotherapy within the DRKS00004519 Trial (RAS-AZIC) of the East German Study Group of Hematology and Oncology (OSHO)

Nadja Jaekel, Susann Schulze, MD, Udo Siebolts, MD, Anja Haak, PhD, Nikolaos Pazaitis, MD, Michael Cross, PhD, Dietger Niederwieser, MD, Mathias Hänel, MD, Georg Maschmeyer, MD, Maxi Wass, MD, Lukas Heukamp, MB PhD, Roopika Menon, Miriam Bertrand, Claudia Wickenhauser, MD, Oana Brosteanu, PhD, Haifa Kathrin Al-Ali, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1420.
https://doi.org/10.1182/blood-2019-127865
Published: 2019
Journal Articles

Nilotinib Vs Nilotinib Plus Pegylated Interferon α (Peg-IFN) Induction and Nilotinib or Peg-IFN Maintenance Therapy for Newly Diagnosed BCR-ABL1 Positive Chronic Myeloid Leukemia Patients in Chronic Phase (TIGER Study): The Addition of Peg-IFN Is Associated with Higher Rates of Deep Molecular Response

Andreas Hochhaus, MD, Andreas Burchert, MD, Susanne Saussele, MD, Gabriela M Baerlocher, MD, Tim H Brümmendorf, MD, Paul La Rosée, MD, Dominik Heim, MD, Stefan W Krause, MD, Philipp D le Coutre, MD, Dietger Niederwieser, MD, Thoralf Lange, MD, Alice Fabarius, PhD, Mathias Hänel, MD, Frank Stegelmann, MD, Jiri Mayer, MD, Arthur Gil, MPH, Danny Himsel, MSc, Joerg Hasford, MD, Rüdiger Hehlmann, MD, Thomas Ernst, MD, Christian Fabisch, Dr.rer.MDc., Markus Pfirrmann, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 495.
https://doi.org/10.1182/blood-2019-130043
Published: 2019
Journal Articles

Outcome at Two Years after a Response-Adapted Approach with Azacitidine and Intensive Chemotherapy in Patients > 60 Years with Newly Diagnosed AML Treated within the DRKS00004519 Trial of the East German Study Group (OSHO)

Nadia Jaekel, MD, Karolin Hubert, Mathias Hänel, MD, Georg Maschmeyer, MD, Regina Herbst, MD, Susann Schulze, MD, Song-Yau Wang, MD, Christoph Kahl, MD, Maxi Wass, MD, Herbert G. Sayer, MD PhD, Oana Brosteanu, PhD, Dietger Niederwieser, MD, Haifa Kathrin Al-Ali
Journal: Blood
Blood (2018) 132 (Supplement 1): 83.
https://doi.org/10.1182/blood-2018-99-115790
Published: 2018
Journal Articles

Chemotherapy-Free Combination of Obinutuzumab and Ibrutinib in First LINE Treatment of Follicular Lymphoma. the Alternative Study By the German Low Grade Lymphoma Study Group (GLSG)

Christian Schmidt, MD, Anna-Katharina Zoellner, Vindi Jurinovic, Martin Sökler, MD, Roswitha Forstpointner, Sascha Haubner, MD, Christian Buske, MD, Andreas Viardot, MD, Ulrich Keller, Christiane Pott, Ullrich Graeven, MD, Reinhard Marks, Mathias Hänel, MD, Ruediger Liersch, Jan Dürig, Eva Hoster, Michael Unterhalt, Wolfgang Hiddemann
Journal: Blood
Blood (2018) 132 (Supplement 1): 448.
https://doi.org/10.1182/blood-2018-99-111692
Published: 2018
Journal Articles

Induction with Bortezomib Melphalan and Prednisolon (VMP) Is Associated with Unexpectedly High Discontinuation Rate in Elderly Multiple Myeloma Patients: First Analysis of the German Maintenance (GERMAIN) Trial

Annamaria Brioli, MD, Kirsi Manz, Mathias Hänel, MD, Markus Pfirrmann, PhD, Andreas Christoph Schwarzer, MD, Marie von Lilienfeld-Toal, MD, Gabriele Prange-Krex, Christian Fabisch, PhD, Stefan Knop, Thomas Illmer, MD, Beate Krammer-Steiner, Andreas Hochhaus, MD, Lars-Olof Mügge, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2016.
https://doi.org/10.1182/blood-2018-99-115964
Published: 2018
Journal Articles

Clinical Characteristics and Outcome in IDH1/2 Mutant AML Patients - Analysis of 3898 Newly Diagnosed Patients with Acute Myeloid Leukemia

Jan Moritz Middeke, MD, Christoph Rollig, MD MSC, Michael Kramer, M.Sc., Alwin Kramer, MD, Tilman Bochtler, MD, Sebastian Scholl, MD, Andreas Hochhaus, MD, Edgar Jost, MD, Tim H. Brümmendorf, MD, Ralph Naumann, MD, Björn Steffen, MD, Volker Kunzmann, MD PhD, Hermann Einsele, MD, Markus Schaich, MD, Andreas Burchert, MD, Andreas Neubauer, Kerstin Schäfer-Eckart, MD, Christoph Schliemann, MD, Stefan W Krause, MD, Regina Herbst, MD, Mathias Hänel, MD, Norbert Frickhofen, MD, Richard Noppeney, MD, Ulrich Kaiser, MD, Claudia D. Baldus, MD, Martin Kaufmann, MD, Zdenek Racil, MD, Sebastian Stasik, PhD, Katja Sockel, MD, Malte von Bonin, MD, Carsten Müller-Tidow, Uwe Platzbecker, Wolfgang E. Berdel, MD, Jiri Mayer, MD, Hubert Serve, MD, Gerhard Ehninger, MD, Johannes Schetelig, MD MSc, Christian Thiede, MD, Friedrich Stoelzel
Journal: Blood
Blood (2018) 132 (Supplement 1): 1461.
https://doi.org/10.1182/blood-2018-99-118128
Published: 2018
Journal Articles

EZH2 Mutations and Impact on Clinical Outcome Analyzed in 1604 Patients with Acute Myeloid Leukemia

Sebastian Stasik, PhD, Jan Moritz Middeke, MD, Michael Kramer, M.Sc., Christoph Rollig, MD MSC, Alwin Krämer, MD, Sebastian Scholl, MD, Andreas Hochhaus, MD, Martina Crysandt, Tim H. Brümmendorf, MD, Ralph Naumann, MD, Björn Steffen, MD, Volker Kunzmann, MD PhD, Hermann Einsele, MD, Markus Schaich, MD, Andreas Burchert, MD, Andreas Neubauer, Kerstin Schäfer-Eckart, MD, Christoph Schliemann, MD, Stefan W Krause, MD, Regina Herbst, MD, Mathias Hänel, MD, Norbert Frickhofen, MD, Richard Noppeney, MD, Ulrich Kaiser, MD, Claudia D. Baldus, MD, Martin Kaufmann, MD, Zdenek Racil, MD, Uwe Platzbecker, Wolfgang E. Berdel, MD, Jiri Mayer, MD, Hubert Serve, MD, Carsten Müller-Tidow, Gerhard Ehninger, MD, Martin Bornhäuser, Johannes Schetelig, MD, Christian Thiede, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1528.
https://doi.org/10.1182/blood-2018-99-114421
Published: 2018
Journal Articles

Circulating Tumor Cells As a Surrogate Marker for Bone Marrow Minimal Residual Disease and an Adverse Prognostic Factor for Patients with Multiple Myelom

Stefanie Huhn, PhD, Mathias Hänel, MD, Thomas Hielscher, PhD, Uta Bertsch, MD, Hans Jürgen Salwender, Norma Peter, MD, Hartmut Kirchner, Helga Bernhard, MD, Martin Vogel, Ralf Angermund, Martin Goerner, MD, Katja C. Weisel, Jan Duering, Igor W Blau, Niels Weinhold, PhD, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4359.
https://doi.org/10.1182/blood.V130.Suppl_1.4359.4359
Published: 2017
Journal Articles

The Addition of Sorafenib to Standard AML Treatment Results in a Substantial Reduction in Relapse Risk and Improved Survival. Updated Results from Long-Term Follow-up of the Randomized-Controlled Soraml Trial

Christoph Rollig, MD MSC, Hubert Serve, Andreas Hüttmann, MD, Richard Noppeney, MD, Carsten Müller-Tidow, Utz Krug, Claudia D. Baldus, MD, Christian H. Brandts, MD, Volker Kunzmann, MD PhD, Hermann Einsele, Alwin Krämer, MD, Kerstin Schäfer-Eckart, MD, Andreas Neubauer, MD, Andreas Burchert, MD, Aristoteles Giagounidis, MD, Stefan W. Krause, Andreas Mackensen, MD, Walter E. Aulitzky, MD, Regina Herbst, MD, Mathias Hänel, MD, Alexander Kiani, Norbert Frickhofen, MD, Johannes Kullmer, Ulrich Kaiser, MD, Hartmut Link, MD PhD, Thomas Geer, MD, Albrecht Reichle, MD, Christian Junghanss, MD, Roland Repp, MD, Frank Heits, MD, Heinz Albert Durk, Thomas Illmer, Martin Bornhäuser, MD, Markus Schaich, MD, Stefani Barbara Parmentier, MD, Martin Goerner, MD, Christian Thiede, MD, Malte von Bonin, MD, Johannes Schetelig, MD, Michael Kramer, M.Sc., Wolfgang E. Berdel, Gerhard Ehninger
Journal: Blood
Blood (2017) 130 (Supplement 1): 721.
https://doi.org/10.1182/blood.V130.Suppl_1.721.721
Published: 2017
Journal Articles

Final Evaluation of Randomized CML-Study IV: 10-Year Survival and Evolution of Terminal Phase

Rüdiger Hehlmann, MD, Michael Lauseker, PhD, Susanne Saussele, MD, Markus Pfirrmann, Stefan W. Krause, MD, Hans-Jochem Kolb, MD, Andreas Neubauer, MD, Dieter K. Hossfeld, Christoph Nerl, MD, Alois Gratwohl, MD, Gabriela M. Baerlocher, Dominik Heim, MD, Tim Henrik Bruemmendorf, Alice Fabarius, PhD, Claudia Haferlach, MD, Brigitte Schlegelberger, MD PhD, Martin C. Müller, MD, Sabine Jeromin, PhD, Ulrike Proetel, PhD, Katharina Kohlbrenner, PhD, Astghik Voskanyan, PhD, Sébastien Rinaldetti, Wolfgang Seifarth, PhD, Birgit Spiess, Leopold Balleisen, MD, Maria E Goebeler, MD, Mathias Hänel, MD, Anthony D. Ho, MD, J Dengler, C Falge, Lothar Kanz, MD, Claus-Henning Köhne, MD, PhD, Andreas Burchert, MD, Michael Kneba, MD PhD, Frank Stegelmann, MD, C Köhne, Hans-Walter Lindemann, C Waller, Michael Pfreundschuh, MD, Karsten Spiekermann, Wolfgang E Berdel, MD, L Müller, Matthias Edinger, MD, Jiri Mayer, Prof, MD SCs, Dietrich W Beelen, MD PhD, Martin Bentz, MD, Hartmut Link, MDPhD, Bernd Hertenstein, MD, R Fuchs, Martin Wernli, MD, F Schlegel, Rudolph Schlag, M de Wit, Lorenz Trümper, MD, H Hebarth, M Hahn, Jörg Thomalla, MD, Christof Scheid, MD, Philippe Schafhausen, MD, Walter Verbeek, MD, Michael J. Eckart, MD, Winfried Gassmann, MD PhD, Antonio Pezzutto, MD, Michael Schenk, Peter Brossart, MD, Thomas Geer, MD, Stephan Bildat, E Schäfer, Andreas Hochhaus, MD, Joerg Hasford
Journal: Blood
Blood (2017) 130 (Supplement 1): 897.
https://doi.org/10.1182/blood.V130.Suppl_1.897.897
Published: 2017
Journal Articles

Real Life Experience with ATRA-Arsenic Trioxide Based Regimen in Acute Promyelocytic Leukemia - Updated Results of the Prospective German Intergroup Napoleon Registry

Uwe Platzbecker, MD, Eva Lengfelder, MD, Kerstin Schäfer-Eckart, MD, Katharina S Götze, MD, Michael Heuser, MD, Felicitas Thol, MD, Helmut R. Salih, MD, Mathias Hänel, MD, Karsten Spiekermann, Sonja Martin, MD, Sigrid Machherndl-Spandl, MD, Volker Kunzmann, MD, Andreas Jakob, MD, Hans-Joachim Tischler, MD, Dirk Niemann, MD, Joerg Mezger, MD, Tilmann Bochtler, MD, Stefan Krause, MD, Maike de Wit, MD, Claudia D. Baldus, MD, Richard Greil, MD, Jochen Greiner, Mark Ringhoffer, MD, Markus Radsak, MD, Mohammed Amen Wattad, MD, Wolff Schmiegel, MD, Elisabeth Koller, MD, Frank Heits, MD, Albrecht Reichle, MD, Stephan Kremers, MD, Andreas Hochhaus, MD, Nadezda Basara, MD, Dominik Wolf, MD, Martin Goerner, MD, Markus Schaich, MD, Harald Biersack, MD, Heinz Kirchen, MD, Thomas Kubin, MD, Gregor Aschauer, MD, Tanja Hesse, MD, Hartmut Link, MD PhD, Heinz Duerk, MDPhD, Dorit Kuerschner, MD, Walter Fiedler, MD, Bernd Hertenstein, MD, Martin Puttrich, Michael Kramer, M.Sc., Michaela Sauer, Wolfgang Hiddemann, Ulrich Duehrsen, MD, Hubert Serve, Christian Thiede, MD, Arnold Ganser, MD, Tim H. Brummendorf, MD, Konstanze Dohner, MD, Martin Bornhäuser, MD, Richard F. Schlenk, MD, Christoph Rollig, MD MSC, Hartmut Döhner, MD, Gerhard Ehninger, Peter Paschka, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2618.
https://doi.org/10.1182/blood.V130.Suppl_1.2618.2618
Published: 2017
Journal Articles

Response-Adapted Lenalidomide Maintenance in Newly Diagnosed, Transplant-Eligible Multiple Myeloma: Results from the Multicenter Phase III GMMG-MM5 Trial

Hartmut Goldschmidt, MD, Elias K Mai, MD, Jan Dürig, MD, Christof Scheid, MD, Katja C. Weisel, Christina Kunz, Uta Bertsch, MD, Thomas Hielscher, PhD, Markus Munder, MD, Hans-Walter Lindemann, Barbara Huegle-Doerr, Dirk Hose, MD, Anja Seckinger, Stefanie Huhn, PhD, Anna Jauch, Bernhard Rabold, Ahmet Elmaagacli, MD, Christian Gerecke, MD, Peter Brossart, MD, Martin Goerner, MD, Helga Bernhard, MD, Martin Hoffmann, MD, Jens Hillengass, MD, Marc-Steffen S Raab, Igor Wolfgang Blau, MD, Mathias Hänel, MD, Hans Jürgen Salwender
Journal: Blood
Blood (2017) 130 (Supplement 1): 400.
https://doi.org/10.1182/blood.V130.Suppl_1.400.400
Published: 2017
Journal Articles

The Prognostic and Predictive Value of IKZF1 and IKZF3 Expression in T-Cells in Patients with Multiple Myeloma

Mohamed H.S. Awwad, Katharina Kriegsmann, MD MBA, Julian Plaumann, Michael Benn, Jens Hillengass, MD, Marc-Steffen S Raab, Uta Bertsch, MD, Markus Munder, MD, Katja C. Weisel, Hans Jürgen Salwender, Mathias Hänel, MD, Roland Fenk, MD, Jan Dürig, MD, Carsten Müller-Tidow, Hartmut Goldschmidt, MD, Michael Hundemer
Journal: Blood
Blood (2017) 130 (Supplement 1): 1846.
https://doi.org/10.1182/blood.V130.Suppl_1.1846.1846
Published: 2017
Journal Articles

Addition of Cyclophosphamide to Pomalidomide and Dexamethasone in Case of Suboptimal Response to Pomalidomide and Dexamethasone Alone in Relapsed and/or Refractory Multiple Myeloma: Results of the GMMG-Perspective Trial

Katja C. Weisel, Hans Jürgen Salwender, Christof Scheid, MD, Manola Zago, Britta Besemer, Mathias Hänel, MD, Jan Dürig, MD, Markus Munder, MD, Hans-Walter Lindemann, Anja Seckinger, Christina Kunz, Axel Benner, Dirk Hose, MD, Anna Jauch, Lothar Kanz, Hartmut Goldschmidt, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1849.
https://doi.org/10.1182/blood.V130.Suppl_1.1849.1849
Published: 2017
Journal Articles

Minimal-Residual Disease Guided Treatment with Azacitidine in MDS/AML Patients at Imminent Risk of Relapse: Results of the Prospective RELAZA2 Trial

Uwe Platzbecker, MD, Jan Moritz Middeke, MD, Katja Sockel, MD, Anke Mütherig, MD, Regina Herbst, MD, Mathias Hänel, MD, Dominik Wolf, MD, Claudia D. Baldus, MD, Lars Fransecky, MD, Richard Noppeney, MD, Gesine Bug, MD, Katharina S Götze, MD, Alwin Krämer, MD, Tilman Bochtler, MD, Karsten Spiekermann, Marion Subklewe, MD, Matthias Stelljes, MD, Christoph Groth, MD, Antje Schubert, Hubert Serve, Ulrich Duehrsen, MD, Johannes Schetelig, MD, Christoph Rollig, MD MSC, Michael Kramer, M.Sc., Gerhard Ehninger, Martin Bornhäuser, MD, Christian Thiede, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 565.
https://doi.org/10.1182/blood.V130.Suppl_1.565.565
Published: 2017
Journal Articles

Allogeneic Stem Cell Transplantation Improves Survival in Patients with FLT 3-ITD-Negative and NPM 1-Wild Type Intermediate Risk (ELN) Acute Myeloid Leukemia

Katharina Heidrich, MD, Christian Thiede, MD, Kerstin Schäfer-Eckart, MD, Norbert Schmitz, MD, Walter E Aulitzky, MD, Alwin Krämer, MD, Wolf Rösler, MD, Mathias Hänel, MD, Hermann Einsele, MD, Claudia D. Baldus, MD, Ralf U Trappe, MD, Friedrich Stölzel, MD, Jan Moritz Middeke, MD, Christoph Röllig, MD, Michael Kramer, MSc, Hubert Serve, MD, Wolfgang E Berdel, MD, Gerhard Ehninger, MD, Martin Bornhäuser, MD, Johannes Schetelig, MD MSc
Journal: Blood
Blood (2016) 128 (22): 3493.
https://doi.org/10.1182/blood.V128.22.3493.3493
Published: 2016
Journal Articles

Long Term Follow up and Impact of Comorbidity Prior to Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Relapsed or Refractory AML - Lessons Learned from the Prospective Bridge Trial -

Jan Moritz Middeke, MD, Regina Herbst, MD, Stefani Barbara Parmentier, MD, Gesine Bug, MD, Mathias Hänel, MD, Gernot Stuhler, Kerstin Schäfer-Eckart, MD, Wolf Rösler, MD, Stefan A. Klein, MD, Wolfgang Bethge, MD, Nael Alakel, MD, Markus Schaich, MD, Anke Morgner, MD, Michael Kramer, MSc, Katja Sockel, MD, Malte von Bonin, MD, Friedrich Stölzel, MD, Uwe Platzbecker, MD, Christoph Röllig, MD, Christian Thiede, MD, Gerhard Ehninger, MD, Martin Bornhäuser, MD, Johannes Schetelig, MD MSc
Journal: Blood
Blood (2016) 128 (22): 4692.
https://doi.org/10.1182/blood.V128.22.4692.4692
Published: 2016