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Journal Articles

RNA Splicing Factor Mutations Drive Aberrant Canonical and Cryptic Circular RNA Biogenesis in Leukemia

Mike Fernandez, Meiling Jin, Qiong Jia, Yiming Wu, Kevyn Hart, Emilee Bargoma, Joseph Pangallo, Robert K. Bradley, Omar Abdel-Wahab, Zhenyu Jia, Ren-Jang Lin, Lili Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1395.
https://doi.org/10.1182/blood-2023-174135
Published: 2023
Journal Articles

Disrupting MGA-MYC Driven Metabolic Reprogramming in Richter's Syndrome Pre-Clinical Models Via Novel Therapeutic Approaches

Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Hart, Joo Y. Song, Wing C Chan, Tanya Siddiqi, Alexey V Danilov, Steve T Rosen, Lili Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9842–9843.
https://doi.org/10.1182/blood-2022-162664
Published: 2022
Journal Articles

MGA deletion Leads to Richter's Transformation Via NME1

Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Hart, Joo Y. Song, John Chan, Raju Pillai, Tanya Siddiqi, Alexey V. Danilov, Steven T. Rosen, Lili Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 252.
https://doi.org/10.1182/blood-2021-148953
Published: 2021
Journal Articles

METTL3 Dysregulates RNA Splicing by Translational Control of Splicing Factors via m 6 A Modification in CLL

Yiming Wu, Meiling Jin, Mike Fernandez, Kevyn Hart, Aijun Liao, Stacey M. Fernandes, Tinisha McDonald, Lucy Ghoda, Daniel Roeth, Markus Kalkum, Raju Pillai, Jianjun Chen, Jennifer R Brown, Alexey V. Danilov, Steven T. Rosen, Tanya Siddiqi, Lili Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 499.
https://doi.org/10.1182/blood-2021-149691
Published: 2021
Journal Articles

R-Loop Associated Mitotic Stress Confers Vulnerabilities in Splicing Factor Mutant Leukemia

Martina Cusan, Meiling Jin, Bo Zhang, Mike Fernandez, Aijun Liao, Lu Yang, Yiming Wu, Prajish Iyer, Kevyn Hart, Catherine Gutierrez, Jeremy Stark, Teresa V. Bowman, Catherine J. Wu, Ren-Jang Lin, Lili Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3713.
https://doi.org/10.1182/blood-2021-151298
Published: 2021
Journal Articles

Genomic and Transcriptomic Profiling Reveals Distinct Subsets Associated with Outcomes in Mantle Cell Lymphoma

Yuting Yan, Shuhua Yi, MD, Meiling Jin, PhD, Yi Wang, Ying Yu, Wang Jun, Dehui Zou, MD, Tingyu Wang, Zhen Yu, MD, Lanting Liu, Rui Cui, MD, Wei Liu, Ryu Lv, Weiwei Sui, MD, Wenyang Huang, Xiong Wenjie, Huijun Wang, Qi Sun, Mu Hao, Jianxiang Wang, MD, Cheng Tao, Lugui Qiu, MD, Lili Wang, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-139955
Published: 2020
Journal Articles

Integrative Transcriptome and Quantitative Proteome Analyses Identify METTL3 As a Key Regulator for Aberrant RNA Processing in Chronic Lymphocytic Leukemia

Yiming Wu, PhD, Meiling Jin, PhD, Kevyn Hart, BS, Aijun Liao, MD PhD, Stacey M. Fernandes, BS, Tinisha McDonald, BS, Lucy Brown, PhD, Daniel Roeth, PhD, Markus Kalkum, PhD, Raju Pillai, MD, Jianjun Chen, PhD, Jennifer R Brown, MD PhD, Steven T. Rosen, MD, Tanya Siddiqi, MD, Lili Wang, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12.
https://doi.org/10.1182/blood-2020-139841
Published: 2020
Journal Articles

Expression of Sf3b1-K700E accelerates the Development of Chronic Lymphocytic Leukemia in a Del (13q) Murine Model

Bo Zhang, MDPhD, Prajish Iyer, PhD, Meiling Jin, PhD, Elisa Ten Hacken, PhD, Zachary Cartun, BS, Kevyn Hart, BS, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, Donna S. Neuberg, ScD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD, Lili Wang, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4–5.
https://doi.org/10.1182/blood-2020-139096
Published: 2020
Journal Articles

Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion

Yan Xiu, Qianze Dong, Lin Fu, Aaron Bossler, Xiaobing Tang, Brendan Boyce, Nicholas Borcherding, Mariah Leidinger, José Luis Sardina, Hai-hui Xue, Qingchang Li, Andrew Feldman, Iannis Aifantis, Francesco Boccalatte, Lili Wang, Meiling Jin, Joseph Khoury, Wei Wang, Shimin Hu, Youzhong Yuan, Endi Wang, Ji Yuan, Siegfried Janz, John Colgan, Hasem Habelhah, Thomas Waldschmidt, Markus Müschen, Adam Bagg, Benjamin Darbro, Chen Zhao
Journal: Blood
Blood (2020) 135 (2): 108–120.
https://doi.org/10.1182/blood.2019001438
Published: 2020
Includes: Supplemental data
Journal Articles

High Frequency Mutations of MYD88 and KMT2D in Chinese Chronic Lymphocytic Leukemia

Shuhua Yi, MD, Yuting Yan, Meiling Jin, Dr., Wenjie Xiong, Zengjun Li, Ying Yu, Rui Cui, MD, Zhen Yu, MD, Yani Lin, Wang Jun, Tingyu Wang, Wei Liu, Kun Ru, MD, Lili Wang, MD PhD, Lugui Qiu, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2761.
https://doi.org/10.1182/blood-2019-123194
Published: 2019