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Journal Articles

Characterization of the bone marrow niche in patients with chronic myeloid leukemia identifies CXCL14 as a new therapeutic option

Blood (2023) 142 (1): 73–89.

https://doi.org/10.1182/blood.2022016896

Published: 2023

Includes: Supplemental data

Journal Articles

EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene

Rajesh Somasundaram, Christina T. Jensen, Johanna Tingvall-Gustafsson, Josefine Åhsberg, Kazuki Okuyama, Mahadesh Prasad, James R. Hagman, Xun Wang, Shamit Soneji, Tobias Strid, Jonas Ungerbäck, Mikael Sigvardsson

Blood (2021) 137 (22): 3037–3049.

https://doi.org/10.1182/blood.2020009564

Published: 2021

Includes: Supplemental data

Journal Articles

13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking

Minjun Yang, Setareh Safavi, Eleanor L. Woodward, Nicolas Duployez, Linda Olsson-Arvidsson, Jonas Ungerbäck, Mikael Sigvardsson, Marketa Zaliova, Jan Zuna, Thoas Fioretos, Bertil Johansson, Karolin H. Nord, Kajsa Paulsson

Blood (2020) 136 (8): 946–956.

https://doi.org/10.1182/blood.2019004684

Published: 2020

Includes: Supplemental data

Journal Articles

Wipping p53 into subservience in B-cell development

Mikael Sigvardsson

Blood (2015) 126 (5): 566–567.

https://doi.org/10.1182/blood-2015-06-649475

Published: 2015

Journal Articles

Transcription factor networks in B-cell differentiation link development to acute lymphoid leukemia

Rajesh Somasundaram, Mahadesh A. J. Prasad, Jonas Ungerbäck, Mikael Sigvardsson

Blood (2015) 126 (2): 144–152.

https://doi.org/10.1182/blood-2014-12-575688

Published: 2015

Journal Articles

Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency

Mahadesh A. J. Prasad, Jonas Ungerbäck, Josefine Åhsberg, Rajesh Somasundaram, Tobias Strid, Malin Larsson, Robert Månsson, Ayla De Paepe, Henrik Lilljebjörn, Thoas Fioretos, James Hagman, Mikael Sigvardsson

Blood (2015) 125 (26): 4052–4059.

https://doi.org/10.1182/blood-2014-12-617282

Published: 2015

Includes: Supplemental data

Journal Articles

Identification Of Bipotential Lin - CD34 + CD38 - Integrin α2 - Erythrocyte-Megakaryocyte Progenitors In Human Bone Marrow

Wan Man Wong, Mikael Sigvardsson, Hong Qian, Marja Ekblom, MD, PhD

Blood (2013) 122 (21): 2423.

https://doi.org/10.1182/blood.V122.21.2423.2423

Published: 2013

Journal Articles

An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state

Martin Wahlestedt, Gudmundur L. Norddahl, Gerd Sten, Amol Ugale, Mary-Ann Micha Frisk, Ragnar Mattsson, Tomas Deierborg, Mikael Sigvardsson, David Bryder

Blood (2013) 121 (21): 4257–4264.

https://doi.org/10.1182/blood-2012-11-469080

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment

Wei Xu, Tiffany Carr, Kevin Ramirez, Stephanie McGregor, Mikael Sigvardsson, Barbara L. Kee

Blood (2013) 121 (9): 1534–1542.

https://doi.org/10.1182/blood-2012-08-449447

Published: 2013

Includes: Supplemental data

Journal Articles

Transcription factor dose links development to disease

Mikael Sigvardsson

Blood (2012) 120 (18): 3630–3631.

https://doi.org/10.1182/blood-2012-09-455113

Published: 2012

Journal Articles

Enhanced Cytokine Responsiveness Counteracts Age-Induced Decline in Hematopoietic Stem Cell Function

Gudmundur L Norddahl, Martin Wahlestedt, Santiago Gisler, Mikael Sigvardsson, David Bryder

Blood (2011) 118 (21): 2342.

https://doi.org/10.1182/blood.V118.21.2342.2342

Published: 2011

Journal Articles

IL-7 mediates Ebf-1–dependent lineage restriction in early lymphoid progenitors

Panagiotis Tsapogas, Sasan Zandi, Josefine Åhsberg, Jenny Zetterblad, Eva Welinder, Jan Ingvar Jönsson, Robert Månsson, Hong Qian, Mikael Sigvardsson

Blood (2011) 118 (5): 1283–1290.

https://doi.org/10.1182/blood-2011-01-332189

Published: 2011

Includes: Supplemental data

Journal Articles

Temporal and Sequential Expression of EBF1 and PAX5 Restricts the Non-B Cell Fate In Early Lymphopoiesis

Sasan Zandi, MD, Jenny Zetterblad, PhDstudent, Panagiotis Tsapogas, PhD, Robert Månsson, PhD, Mikael Sigvardsson, Prof.

Blood (2010) 116 (21): 3867.

https://doi.org/10.1182/blood.V116.21.3867.3867

Published: 2010

Journal Articles

Mesenchymal Stem and Progenitor Cells In the Mouse Bone Marrow Lack Expression of CD44.

Hong Qian, Mikael Sigvardsson

Blood (2010) 116 (21): 2581.

https://doi.org/10.1182/blood.V116.21.2581.2581

Published: 2010

Journal Articles

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity

Robert Mansson, Sasan Zandi, Eva Welinder, Panagiotis Tsapogas, Nobuo Sakaguchi, David Bryder, Mikael Sigvardsson

Blood (2010) 115 (13): 2601–2609.

https://doi.org/10.1182/blood-2009-08-236398

Published: 2010

Includes: Supplemental data

Journal Articles

Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells

Holger Weishaupt, Mikael Sigvardsson, Joanne L. Attema

Blood (2010) 115 (2): 247–256.

https://doi.org/10.1182/blood-2009-07-235176

Published: 2010

Includes: Supplemental data

Journal Articles

Early B-Cell Factor 2 Represents A Novel Marker of Highly Purified Messenchymal Stem-Like Cells in Mouse Bone Marrow.

Hong Qian, Mikael Sigvardsson

Blood (2009) 114 (22): 252.

https://doi.org/10.1182/blood.V114.22.252.252

Published: 2009

Journal Articles

IL7 Counteraction with Notch Signaling Followed by EBF1 Expression Marks the B-Cell Commitment in CLP Stage

Sasan Zandi, MD, Panagiotis Tsapogas, PhD, Robert Månsson, PhD, Mikael Sigvardsson

Blood (2008) 112 (11): 2452.

https://doi.org/10.1182/blood.V112.11.2452.2452

Published: 2008

Journal Articles

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells

Robert Mansson, Sasan Zandi, Kristina Anderson, Inga-Lill Martensson, Sten Eirik W. Jacobsen, David Bryder, Mikael Sigvardsson

Blood (2008) 112 (4): 1048–1055.

https://doi.org/10.1182/blood-2007-11-125385

Published: 2008

Includes: Supplemental data

Journal Articles

Permissive roles of hematopoietin and cytokine tyrosine kinase receptors in early T-cell development

Christina T. Jensen, Charlotta Böiers, Shabnam Kharazi, Anna Lübking, Tobias Rydén, Mikael Sigvardsson, Ewa Sitnicka, Sten Eirik W. Jacobsen

Blood (2008) 111 (4): 2083–2090.

https://doi.org/10.1182/blood-2007-08-108563

Published: 2008

Includes: Supplemental data

NARROW

Characterization of the bone marrow niche in patients with chronic myeloid leukemia identifies CXCL14 as a new therapeutic option

EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene

13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking

Wipping p53 into subservience in B-cell development

Transcription factor networks in B-cell differentiation link development to acute lymphoid leukemia

Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency

Identification Of Bipotential Lin - CD34 + CD38 - Integrin α2 - Erythrocyte-Megakaryocyte Progenitors In Human Bone Marrow

An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state

E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment

Transcription factor dose links development to disease

Enhanced Cytokine Responsiveness Counteracts Age-Induced Decline in Hematopoietic Stem Cell Function

IL-7 mediates Ebf-1–dependent lineage restriction in early lymphoid progenitors

Temporal and Sequential Expression of EBF1 and PAX5 Restricts the Non-B Cell Fate In Early Lymphopoiesis

Mesenchymal Stem and Progenitor Cells In the Mouse Bone Marrow Lack Expression of CD44.

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity

Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells

Early B-Cell Factor 2 Represents A Novel Marker of Highly Purified Messenchymal Stem-Like Cells in Mouse Bone Marrow.

IL7 Counteraction with Notch Signaling Followed by EBF1 Expression Marks the B-Cell Commitment in CLP Stage

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells

Permissive roles of hematopoietin and cytokine tyrosine kinase receptors in early T-cell development

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American Society of Hematology

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American Society of Hematology

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