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Journal Articles

Fetal context conveys heritable protection against MLL-rearranged AML that depends on MLL3

Open Access
Jonny Mendoza-Castrejon, Wei Yang, Elisabeth Denby, Helen C. Wang, Emily B. Casey, Rohini Muthukumar, Riddhi M. Patel, Jihye Yoon, Yanan Li, J. Michael White, Ran Chen, Luis F. Z. Batista, Jeffrey A. Magee
Journal: Blood
Blood (2026) 147 (1): 61–72.
https://doi.org/10.1182/blood.2025029686
Published: 2026
Includes: Supplemental data
Journal Articles

MLL3 and MLL4 maintain hematopoietic stem cell multipotency by actively opposing a B-cell default state

Free
Helen Wang, Ran Chen, Wei Yang, Tingting Hu, Riddhi Patel, Emily Casey, Elisabeth Denby, Run Zhang, Jeffrey Bednarski, Jeffrey Magee
Journal: Blood
Blood (2025) 146 (Supplement 1): 208.
https://doi.org/10.1182/blood-2025-208
Published: 2025
Journal Articles

Critical role for MLL3-phd domains in HSC self-renewal and AML suppression

Free
Rohini Muthukumar, Helen Wang, Ran Chen, Elisabeth Denby, Riddhi Patel, Emily Casey, Jeffrey Magee
Journal: Blood
Blood (2025) 146 (Supplement 1): 4928.
https://doi.org/10.1182/blood-2025-4928
Published: 2025
Journal Articles

Divergent Roles of MLL3 and MLL4 in Hematopoietic Stem Cell Fate Decision

Free
Helen C. Wang, Ran Chen, Wei Yang, Riddhi M. Patel, Emily B. Casey, Elisabeth Denby, Jeffrey Magee
Journal: Blood
Blood (2023) 142 (Supplement 1): 400.
https://doi.org/10.1182/blood-2023-178765
Published: 2023
Journal Articles

The BCMA-Targeted Fourth-Generation CAR-T Cells Secreting CST6 Against Multiple Myeloma and Suppresses Osteolytic Lesions

Free
Fumou Sun, Yan Cheng, Jin-Ran Chen, Visanu Wanchai, David E. Mery, Hongwei Xu, Dongzheng Gai, Samer Al Hadidi, Carolina Schinke, Sharmilan Thanendrarajan, Maurizio Zangari, Frits van Rhee, John D Shaughnessy, Jr, Guido Tricot, Fenghuang Zhan
Journal: Blood
Blood (2023) 142 (Supplement 1): 452.
https://doi.org/10.1182/blood-2023-181853
Published: 2023
Journal Articles

KMT2C/ MLL3 Attenuates Committed Myeloid Progenitor Self-Renewal Capacity and Balances Granulocyte and Monocyte/Dendritic Cell Output

Free
Helen C. Wang, Ran Chen, Wei Yang, Riddhi M Patel, Emily B Casey, Jeffrey A. Magee
Journal: Blood
Blood (2022) 140 (Supplement 1): 4485–4486.
https://doi.org/10.1182/blood-2022-165717
Published: 2022
Journal Articles

Haploid Kmt2c Deletions Enhance Hematopoietic Stem Cell Mobilization in Response to Granulocyte-Colony Stimulating Factor

Free
Ran Chen, Riddhi M Patel, Emily B Casey, Jeffrey A. Magee
Journal: Blood
Blood (2021) 138 (Supplement 1): 2762.
https://doi.org/10.1182/blood-2021-147914
Published: 2021
Journal Articles

CST6 Is a Small Autocrine Molecule That Targets Myeloma Growth and Bone Destruction

Free
Dongzheng Gai, MD, Stewart JP, Xuxing Shen, Jin-Ran Chen, PhD, Can Li, MD, Bailu Peng, PhD, Ya-Wei Qiang, MD PhD, Shmuel Yaccoby, PhD, Maurizio Zangari, MD FACP, Frits van Rhee, MD, Guido J. Tricot, MD PhD, Lijuan Chen, MDPhD, John Shaughnessy, Jr., PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 21.
https://doi.org/10.1182/blood-2020-140568
Published: 2020
Journal Articles

Kmt2c Limits the Self-Renewal Capacity of Multiply Divided HSCs By Promoting Sensitivity to Interleukin-1

Free
Ran Chen, PhD, Theresa O. Owuor, PhD, Riddhi M Patel, BS, Emily Casey, Jeffrey A. Magee, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3711.
https://doi.org/10.1182/blood-2019-126229
Published: 2019