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Rathan Kumar
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Journal Articles

Bromodomain and extra-terminal domain (BET) as a therapeutic target in a mouse model of secondary hemophagocytic lymphohistiocytosis (HLH)

Free
Paola Marra, Rathan Kumar, Charlene Mao, Sydney Leon, Ian Hout, Robert Baiocchi, Parvarthi Ranganathan, Polina Shindiapina
Journal: Blood
Blood (2025) 146 (Supplement 1): 2987.
https://doi.org/10.1182/blood-2025-2987
Published: 2025
Journal Articles

The bromodomain and extra-terminal domain protein BRD4 promotes both self renewal and inflammation in TET2 mutated clonal hematopoiesis

Free
Alexander Marr, Madeline Halpin, Dominique Corbin, Britten Gordon, Somi Benrashid, Ethan Whipp, Mehdi Gharghabi, Jean Truxall, Olivia Cahn, Rathan Kumar, Parvarthi Ranganathan, Bethany Mundy-Bosse, Jennifer Woyach, Julia Cooper, Marina Beltrami Moreira, Jayanshu Jain, James Blachly, Uma Borate, Rosa Lapalombella, Nicole Grieselhuber
Journal: Blood
Blood (2025) 146 (Supplement 1): 1398.
https://doi.org/10.1182/blood-2025-1398
Published: 2025
Journal Articles

BET inhibition targets pathogenic interstitial macrophages to limit antibody mediated fibrosis in bronchiolitis obliterans chronic gvhd

Free
Rathan Kumar, Lotus Neidemire-Colley, Elizabeth Garfinkle, Camryn Steere, Simran Surana, Annie Murray, Giorgia Giordano, Olivia Martin, Emerson Woodbury, Kara Corps, Malith Karunasiri, Mathew Gorr, Loren Wold, Kenneth Oestreich, Nicole Grieselhuber, Bruce Blazar, Ivan Maillard, Katherine Miller, Hannah Choe, Parvarthi Ranganathan
Journal: Blood
Blood (2025) 146 (Supplement 1): 5859.
https://doi.org/10.1182/blood-2025-5859
Published: 2025
Journal Articles

Bromodomain/Extra-Terminal Inhibition (BETi) and Ruxolitinib: Immune Profiling Insights from Human Samples in Acute Gvhd

Free
Manan Shah, Rathan Kumar, Lotus Neidemire-Colley, Mandi Zhu, Nicholas Yuhasz, Malith Karunasiri, Parvathi Ranganathan, Hannah Choe
Journal: Blood
Blood (2024) 144 (Supplement 1): 4906.
https://doi.org/10.1182/blood-2024-199900
Published: 2024
Journal Articles

Comparing Immune Reconstitution in Post-Transplant Cy Myeloablative Vs Reduced Intensity Transplants: Notable Trends in Monocyte Population

Free
Manan Shah, Mandi Zhu, Rathan Kumar, Malith Karunasiri, Lotus Neidemire-Colley, Nicholas Yuhasz, Elizabeth Miller, Marcos de Lima, Parvathi Ranganathan, Hannah Choe
Journal: Blood
Blood (2024) 144 (Supplement 1): 7336.
https://doi.org/10.1182/blood-2024-201863
Published: 2024
Journal Articles

Inhibition of Bromodomain and Extraterminal Domain (BET) Proteins Alleviates Chronic Graft- Versus -Host-Disease Via Modulating the CXCR5/CXCL13 Axis

Free
Rathan Kumar, Lotus Neidermire-Colley, Charlie Spencer, David Aslaner, Yandi Gao, Simran Surana, Matthew W Gorr, Katiri Snyder, Malith Karunasiri, Loren E Wold, Gideon Bollag, Ben Powell, Hannah Choe, Parvathi Ranganathan
Journal: Blood
Blood (2023) 142 (Supplement 1): 2047.
https://doi.org/10.1182/blood-2023-182354
Published: 2023