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Robert Carlson
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Journal Articles

Selective inhibition of nuclear export with selinexor in patients with non-Hodgkin lymphoma

Clinical Trials & Observations
John Kuruvilla, Michael Savona, Rachid Baz, Paul Morten Mau-Sorensen, Nashat Gabrail, Ramiro Garzon, Richard Stone, Michael Wang, Lynn Savoie, Peter Martin, Ian Flinn, Meagan Jacoby, Thaddeus J. Unger, Jean-Richard Saint-Martin, Tami Rashal, Sharon Friedlander, Robert Carlson, Michael Kauffman, Sharon Shacham, Martin Gutierrez
Journal: Blood
Blood (2017) 129 (24): 3175–3183.
https://doi.org/10.1182/blood-2016-11-750174
Published: 2017
Includes: Supplemental data
Journal Articles

A phase 1 clinical trial of single-agent selinexor in acute myeloid leukemia

Clinical Trials & Observations
Ramiro Garzon, Michael Savona, Rachid Baz, Michael Andreeff, Nashat Gabrail, Martin Gutierrez, Lynn Savoie, Paul Morten Mau-Sorensen, Nina Wagner-Johnston, Karen Yee, Thaddeus J. Unger, Jean-Richard Saint-Martin, Robert Carlson, Tami Rashal, Trinayan Kashyap, Boris Klebanov, Sharon Shacham, Michael Kauffman, Richard Stone
Journal: Blood
Blood (2017) 129 (24): 3165–3174.
https://doi.org/10.1182/blood-2016-11-750158
Published: 2017
Includes: Supplemental data
Journal Articles

Safety, Efficacy, and Determination of the Recommended Phase 2 Dose for the Oral Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330)

Christine Chen, MD, Ramiro Garzon, MD, Martin Gutierrez, Meagan A. Jacoby, MD PhD, Peter Brown, Ian Flinn, Richard M. Stone, MD, Mary Lynn Savoie, MD, Rachid Baz, Nashat Y. Gabrail, MD, Michael Wang, MD, Peter Martin, MD, David Siegel, MD PhD, Morten Mau-Sørensen, Michael Andreef, Tracey Marshall, Jean-Richard Saint-Martin, Robert Carlson, Sharon Shacham, Michael Kauffman, John Kuruvilla, MD
Journal: Blood
Blood (2015) 126 (23): 258.
https://doi.org/10.1182/blood.V126.23.258.258
Published: 2015
Journal Articles

Selinexor-Induced Thrombocytopenia Results from the Inhibition of Megakaryocyte Progenitor Cells in the Early Stage of Megakaryopoiesis

Kellie R Machlus, PhD, Stephen Wu, Robert Carlson, PhD, Sharon Friedlander, PhD, Trinayan Kashyap, MSc, Ori Kalid, PhD, Eran Shacham, PhD, Tami Rashal, MD, Sharon Shacham, PhD MBA, Joseph E Italiano, PhD, Yosef Landesman, PhD
Journal: Blood
Blood (2014) 124 (21): 1458.
https://doi.org/10.1182/blood.V124.21.1458.1458
Published: 2014
Journal Articles

Selinexor Demonstrates Marked Synergy with Dexamethasone (Sel-Dex) in Preclinical Models and in Patients with Heavily Pretreated Refractory Multiple Myeloma (MM)

Christine I. Chen, MD MD FRCPC, Martin Gutierrez, MD, David S. Siegel, MD PhD, Joshua R. Richter, MD, Nina Wagner-Johnston, Craig C Hofmeister, MD MPH, Jesus G. Berdeja, MD, Nashat Gabrail, MD, Rachid Baz, MD, Morten Mau-Sorensen, MD, Suzanne Trudel, MD MSC, FRCPC, Rodger E. Tiedemann, MD PhD, Vishal Kukreti, MD, Nuchanan Areethamsirikul, MD, Asfar Azmi, PhD, Trinayan Kashyap, MSc, Yosef Landesman, PhD, Tracey Marshall, John McCartney, PhD, Jean-Richard Saint-Martin, Sasha Norori, MSc, Michael R Savona, MD, Tami Rashal, MD, Robert Carlson, PhD, Mansoor R Mirza, MD, Sharon Shacham, PhDMBA, Michael Kauffman, MD PhD, Donna E Reece, MD FRCPC
Journal: Blood
Blood (2014) 124 (21): 4773.
https://doi.org/10.1182/blood.V124.21.4773.4773
Published: 2014
Journal Articles

In Vitro and in Vivo Quantification of Exportin-1 (XPO1) Occupancy By the Oral Selective Inhibitor of Nuclear Export (SINE) Selinexor in Multiple Myeloma, Acute Myeloid Leukemia, and Healthy PBMCs

Marsha Crochiere, PhD, Boris Klebanov, M.A., MsC, Erkan Baloglu, PhD, Ori Kalid, PhD, Trinayan Kashyap, MSc, William Senapedis, PhD, Diego del Alamo, BS, Tami Rashal, MD, Sharon Tamir, PhD, Dilara McCauley, PhD, Robert Carlson, PhD, Michael Savona, MD, Michael Kauffman, MD PhD, Sharon Shacham, PhDMBA, Yosef Landesman, PhD
Journal: Blood
Blood (2014) 124 (21): 5196.
https://doi.org/10.1182/blood.V124.21.5196.5196
Published: 2014
Journal Articles

The Oral Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) Demonstrates Broad and Durable Clinical Activity in Relapsed / Refractory Non Hodgkin’s Lymphoma (NHL)

John Kuruvilla, MD, John C. Byrd, MD, Joseph M Flynn, Ramiro Garzon, MD, Pierluigi Porcu, MD, Nina Wagner-Johnston, Mary Lynn Savoie, MD FRCPC, Richard M. Stone, MD, Eric D. Jacobsen, MD, Morten Mau-Sorensen, MD, Peter de Nully Brown, Rachid Baz, MD, Bijal Shal, MD, Ian Flinn, Nashat Gabrail, MD, Vishal Kukreti, MD, Rodger E. Tiedemann, MD PhD, Yosef Landesman, PhD, Boris Klebanov, M.A., MsC, Eran Shacham, PhD, Jean-Richard Saint-Martin, Tracey Marshall, John McCartney, PhD, Dilara McCauley, PhD, Robert Carlson, PhD, Sasha Norori, MSc, Michael R Savona, MD, Tami Rashal, MD, Mansoor R Mirza, MD, Michael Kauffman, MD PhD, Sharon Shacham, PhD MBA
Journal: Blood
Blood (2014) 124 (21): 396.
https://doi.org/10.1182/blood.V124.21.396.396
Published: 2014