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Journal Articles

Dynamic BH3 Profiling As Pharmacodynamic Biomarker for the Activity of BH3 Mimetics

Rongqing Pan, PhD, Youzhen Wang, Shumei Qiu, Jeremy Ryan, Ensar Halilovic

Blood (2020) 136 (Supplement 1): 6.

https://doi.org/10.1182/blood-2020-138916

Published: 2020

Journal Articles

Upregulation of MAPK/MCL-1 Maintaining Mitochondrial Oxidative Phosphorylation Confers Acquired Resistance to BCL-2 Inhibitor Venetoclax in AML

Qi Zhang, MD PhD, Lina Han, MD PhD, Ce Shi, MD PhD, Rongqing Pan, MS, Man Chun John MA, PhD, Jeremy Ryan, PhD, Stephen E Kurtz, PhD, Hong Mu, MD PhD, Vivian Ruvolo, MS, Helen Ma, MS, Michael Andreeff, MD PhD, Yingchang Mi, MD PhD, Jeffrey W. Tyner, PhD, Joel Leverson, Anthony Letai, MD PhD, Richard Eric Davis, MD, Marina Konopleva, MD PhD

Blood (2016) 128 (22): 101.

https://doi.org/10.1182/blood.V128.22.101.101

Published: 2016

Journal Articles

BCL-2 Inhibition By ABT-199 (Venetoclax/GDC-0199) and p53 Activation By RG7388 (Idasanutlin) Reciprocally Overcome Leukemia Apoptosis Resistance to Either Strategy Alone: Efficacy and Mechanisms

Rongqing Pan, MS, Vivian Ruvolo, MS, Hong Mu, MD PhD, Zhuanzhen Zheng, PhD, Joel Leverson, PhD, Kensuke Kojima, PhD, Marina Konopleva, MD PhD, Gwen Nichols, MD, Michael Andreeff, MD PhD

Blood (2015) 126 (23): 673.

https://doi.org/10.1182/blood.V126.23.673.673

Published: 2015

Journal Articles

Role of Mesenchymal Stem Cell Galectin 3 in the AML Tumor Microenvironment

Peter Ruvolo, PhD, Yihua Qiu, MD, Vivian Ruvolo, MS, Rui-Yu Wang, MD PhD, Zhihong Zeng, MD, Jared Burks, PhD, Rongqing Pan, MS, Numsen Hail, Jr., PhD, Teresa McQueen, Suk-Young Yoo, Steven M. Kornblau, MD, Michael Andreeff, MD PhD

Blood (2015) 126 (23): 1198.

https://doi.org/10.1182/blood.V126.23.1198.1198

Published: 2015

Journal Articles

Mechanisms of Acquired Resistance to Venetoclax in Preclinical AML Models

Qi Zhang, Rongqing Pan, MS, Lina Han, PhD, Ce Shi, PhD, Stephen E. Kurtz, PhD, Hong Mu, MD PhD, Helen Ma, Michael Andreeff, MD PhD, Joel Leverson, PhD, Jeffrey W. Tyner, PhD, Yingchang Mi, MD PhD, Marina Konopleva, MD PhD

Blood (2015) 126 (23): 328.

https://doi.org/10.1182/blood.V126.23.328.328

Published: 2015

Journal Articles

Inhibition of Mcl-1 with the pan–Bcl-2 family inhibitor (–)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia

Rongqing Pan, Vivian R. Ruvolo, Jun Wei, Marina Konopleva, John C. Reed, Maurizio Pellecchia, Michael Andreeff, Peter P. Ruvolo

Blood (2015) 126 (3): 363–372.

https://doi.org/10.1182/blood-2014-10-604975

Published: 2015

Includes: Supplemental data

Journal Articles

Activation of p53 By Novel MDM2 Antagonist RG7388 Overcomes AML Inherent and Acquired Resistance to Bcl-2 Inhibitor ABT-199 (GDC-0199)

Rongqing Pan, MS, Kensuke Kojima, MD PhD, Zhuanzhen Zheng, MD PhD, Vivian R Ruvolo, MA, Gwen Nichols, MD, Joel D. Leverson, PhD, Markus Dangl, PhD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD

Blood (2014) 124 (21): 2162.

https://doi.org/10.1182/blood.V124.21.2162.2162

Published: 2014

Journal Articles

Proteomic, Gene Expression, and Micro-RNA Analysis Of Bone Marrow Mesenchymal Stromal Cells In Acute Myeloid Leukemia Identifies Pro-Inflammatory, Pro-Survival Signatures In Vitro and In Vivo

Blood (2013) 122 (21): 3685.

https://doi.org/10.1182/blood.V122.21.3685.3685

Published: 2013

Journal Articles

BCL-2-Selective BH3 Mimetic ABT-199 Is a Potent Agent For Acute Myeloid Leukemia

Rongqing Pan, MS, LaKeisha Debose, MS, Juliana M Benito, PhD, Leonard S Golfman, PhD, Patrick A Zweidler-McKay, MD, PhD, Lina Han, PhD, Karine G. Harutyunyan, PhD, Hong Mu, MD, PhD, Vivian R Ruvolo, MA, Eugene Park, Markus Muschen, MD, PhD, Joel Leverson, PhD, Gautam Borthakur, MD, Hagop M Kantarjian, MD, Peter P. Ruvolo, PhD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD

Blood (2013) 122 (21): 1456.

https://doi.org/10.1182/blood.V122.21.1456.1456

Published: 2013

Journal Articles

Suppression of Mir-93 May Regulate Anti-Oxidant Metabolism in Mesenchymal Stromal Cells Derived From Acute Myeloid Leukemia Patients.

Peter P. Ruvolo, PhD, Rodrigo Jacamo, PhD, Teresa McQueen, BS, Rongqing Pan, BS, Ismael Samudio, PhD, Marina Konopleva, MD, PhD, Steven M. Kornblau, MD, Ramiro Garzon, MD, Carlo M. Croce, MD, Michael Andreeff, MD, PhD

Blood (2012) 120 (21): 2354.

https://doi.org/10.1182/blood.V120.21.2354.2354

Published: 2012

NARROW

Dynamic BH3 Profiling As Pharmacodynamic Biomarker for the Activity of BH3 Mimetics

Upregulation of MAPK/MCL-1 Maintaining Mitochondrial Oxidative Phosphorylation Confers Acquired Resistance to BCL-2 Inhibitor Venetoclax in AML

BCL-2 Inhibition By ABT-199 (Venetoclax/GDC-0199) and p53 Activation By RG7388 (Idasanutlin) Reciprocally Overcome Leukemia Apoptosis Resistance to Either Strategy Alone: Efficacy and Mechanisms

Role of Mesenchymal Stem Cell Galectin 3 in the AML Tumor Microenvironment

Mechanisms of Acquired Resistance to Venetoclax in Preclinical AML Models

Inhibition of Mcl-1 with the pan–Bcl-2 family inhibitor (–)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia

Activation of p53 By Novel MDM2 Antagonist RG7388 Overcomes AML Inherent and Acquired Resistance to Bcl-2 Inhibitor ABT-199 (GDC-0199)

Proteomic, Gene Expression, and Micro-RNA Analysis Of Bone Marrow Mesenchymal Stromal Cells In Acute Myeloid Leukemia Identifies Pro-Inflammatory, Pro-Survival Signatures In Vitro and In Vivo

BCL-2-Selective BH3 Mimetic ABT-199 Is a Potent Agent For Acute Myeloid Leukemia

Suppression of Mir-93 May Regulate Anti-Oxidant Metabolism in Mesenchymal Stromal Cells Derived From Acute Myeloid Leukemia Patients.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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