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Sajesan Aryal
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Journal Articles

Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia

Xinyue Zhou, Lixia Zhang, Sajesan Aryal, Virginia Veasey, Amanda Tajik, Cecilia Restelli, Steven Moreira, Pengcheng Zhang, Yanfeng Zhang, Kristin J. Hope, Yang Zhou, Changde Cheng, Ravi Bhatia, Rui Lu
Journal: Blood
Blood (2024) 144 (19): 2018–2032.
https://doi.org/10.1182/blood.2023023644
Published: 2024
Includes: Supplemental data
Journal Articles

A Mouse Model of Zhu-Tokita-Takenouchi-Kim Syndrome Reveals Indispensable Son Functions in Myeloid-Lymphoid Lineage Balance and Terminal Differentiation

Leah Gehrs, Lana Vukadin, Mostafa Mohamed, Bohye Park, Huashi Li, Amr Elkholy, Hyung-Gyoon Kim, Xinyue Zhou, Sajesan Aryal, Steve Lim, Rui Lu, Erin Ahn
Journal: Blood
Blood (2023) 142 (Supplement 1): 1301.
https://doi.org/10.1182/blood-2023-190317
Published: 2023
Journal Articles

Decoding the Epigenetic Drivers of Menin-MLL Inhibitor Resistance in KMT2A-Rearranged Acute Myeloid Leukemia

Xinyue Zhou, Lixia Zhang, Sajesan Aryal, Steven Moreira, Virginia Veasey, Kristin J. Hope, Rui Lu
Journal: Blood
Blood (2023) 142 (Supplement 1): 587.
https://doi.org/10.1182/blood-2023-185353
Published: 2023
Journal Articles

Multi-Omics Analysis Reveals That TET2 Loss Epigenetically Primes Monocytes for Inflammatory Responses Via AP-1 Signaling

Matthew Jenkins, Yunli Chu, Sajesan Aryal, Xinyue Zhou, Kirsten Dickerson, Rebecca Dubin, Chad R Potts, Valeriya Kuznetsova, Alana Franceski, Paran Goel, Stanley C Lee, Rui Lu, Robert Welner, P. Brent Ferrell, Jr.
Journal: Blood
Blood (2023) 142 (Supplement 1): 4061.
https://doi.org/10.1182/blood-2023-182278
Published: 2023
Journal Articles

Metabolic adaptation to tyrosine kinase inhibition in leukemia stem cells

Shaowei Qiu, Vipul Sheth, Chengcheng Yan, Juan Liu, Balu K. Chacko, Hui Li, David K. Crossman, Seth D. Fortmann, Sajesan Aryal, Ashley Rennhack, Maria B. Grant, Robert S. Welner, Andrew J. Paterson, Adam R. Wende, Victor M. Darley-Usmar, Rui Lu, Jason W. Locasale, Ravi Bhatia
Journal: Blood
Blood (2023) 142 (6): 574–588.
https://doi.org/10.1182/blood.2022018196
Published: 2023
Includes: Supplemental data
Journal Articles

Metabolic Adaptation to Tyrosine Kinase Inhibition in Chronic Myelogenous Leukemia Stem Cells

Shaowei Qiu, Vipul Sheth, Chengcheng Yan, Juan Liu, Balu K. Chacko, Hui Li, David Crossman, Seth D. Fortmann, Sajesan Aryal, Maria B. Grant, Robert S. Welner, Andrew J. Paterson, Adam R. Wende, Victor M Darley-Usmar, Rui Lu, Jason W. Locasale, Ravi Bhatia
Journal: Blood
Blood (2022) 140 (Supplement 1): 3874–3875.
https://doi.org/10.1182/blood-2022-156631
Published: 2022