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Samantha M. Sarno
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Journal Articles

The Aurora-Kinase Inhibitor R763/AS703569 Exerts Major Growth-Inhibitory and Apoptosis-Inducing Effects on Neoplastic Mast Cells

Barbara Peter, MVM, Harald Herrmann, MD, Karoline V. Gleixner, MD, Emir Hadzijusufovic, MVM, Sylvia Laffer, PhD, Karina Schuch, Winfried Pickl, MD, Samantha M. Sarno, PhD, Michael Willmann, DVM, Peter Valent, MD
Journal: Blood
Blood (2010) 116 (21): 3972.
https://doi.org/10.1182/blood.V116.21.3972.3972
Published: 2010
Journal Articles

The Transcriptional Signature of Kinases Inhibited by the Multi-Targeted Kinase Inhibitor AS703569 Is Associated with Clinical Outcome in Multiple Myeloma (MM): Anti-MM Activity of AS703569 in Preclinical Studies.

Jake Delmore, David N. Cervi, Douglas McMillin, Efstathios Kastritis, Jana Jakubikova, Melissa G. Ooi, Steffen Klippel, Joseph M. Negri, Leutz Buon, Jacob Laubach, Luca Rastelli, Ann Clark, Samantha M. Sarno, Paul G. Richardson, Kenneth C. Anderson, Constantine S. Mitsiades, M.D., Ph.D
Journal: Blood
Blood (2009) 114 (22): 730.
https://doi.org/10.1182/blood.V114.22.730.730
Published: 2009
Journal Articles

Activity of Serono-AS703569, a Dual Inhibitor of Bcr-Abl and Aurora Kinases in Bcr-Abl Transformed Cells, Is Dependent On Aurora B Inhibition, and Is Not Affected by the Presence of the Highly Imatinib Resistant Bcr-Abl Mutation T315I.

Anna Katharina Seitz, Nikolas von Bubnoff, MD, Samantha M. Sarno, Christian Peschel, MD, Justus Duyster, MD
Journal: Blood
Blood (2009) 114 (22): 3247.
https://doi.org/10.1182/blood.V114.22.3247.3247
Published: 2009