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Journal Articles

Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense

Joni M. Prasad, Oleg V. Gorkun, Harini Raghu, Sherry Thornton, Eric S. Mullins, Joseph S. Palumbo, Ya-Ping Ko, Magnus Höök, Tovo David, Shaun R. Coughlin, Jay L. Degen, Matthew J. Flick

Blood (2015) 126 (17): 2047–2058.

https://doi.org/10.1182/blood-2015-04-639849

Published: 2015

Includes: Supplemental data

Journal Articles

Identification of a Racially Dimorphic Variant in the Human Platelet PAR4 Thrombin Receptor Altering Platelet Function and Pharmacologic Inhibition

Leonard C. Edelstein, PhD, Lukas M Simon, Cory R Lindsay, PhD, Xiango Kong, MD, Raul Teruel Montoya, PhD, Benjamin E Tourdot, PhD, Edward Chen, PhD, Lin Ma, Shaun R Coughlin, PhD, Marvin T. Nieman, PhD, Michael Holinstat, PhD, Chad Shaw, PhD, Paul F Bray, MD

Blood (2014) 124 (21): 1434.

https://doi.org/10.1182/blood.V124.21.1434.1434

Published: 2014

Journal Articles

TMEM16F Ion Channel Regulates Calcium-Dependent PS Exposure, Hemostasis, and Thrombosis

Andrew Y. Kim, PhD, Huanghe Yang, PhD, Tovo David, PhD, Jason Tien, Shaun R Coughlin, PhD, Yuh Nung Jan, Ph.D., Lily Jan, PhD

Blood (2012) 120 (21): 1111.

https://doi.org/10.1182/blood.V120.21.1111.1111

Published: 2012

Journal Articles

Carcinoma mucins trigger reciprocal activation of platelets and neutrophils in a murine model of Trousseau syndrome

Bojing Shao, Mark G. Wahrenbrock, Longbiao Yao, Tovo David, Shaun R. Coughlin, Lijun Xia, Ajit Varki, Rodger P. McEver

Blood (2011) 118 (15): 4015–4023.

https://doi.org/10.1182/blood-2011-07-368514

Published: 2011

Journal Articles

Gi-Coupled GPCR Signaling Is Required at Multiple Levels and In Different Lineages In Hematopoiesis.

Marie Terpager, Hiroshi Kataoka, Ivo Cornelissen, Shaun R. Coughlin

Blood (2010) 116 (21): 2635.

https://doi.org/10.1182/blood.V116.21.2635.2635

Published: 2010

Journal Articles

Endothelial and Hematopoietic Tissue Factor Are Unnecessary in Two Mouse Models of Hemostasis and Thrombosis

Tovo H David, David Sulciner, Ivo Cornelissen, Shaun R Coughlin

Blood (2008) 112 (11): 3085.

https://doi.org/10.1182/blood.V112.11.3085.3085

Published: 2008

Journal Articles

GP-VI Disruption Confers Additional Protection against Arterial Thrombosis in PAR-4 Deficient Mice

Ivo Cornelissen, Erica De Candia, Shaun R Coughlin

Blood (2008) 112 (11): 3932.

https://doi.org/10.1182/blood.V112.11.3932.3932

Published: 2008

Journal Articles

Inhibition of the ADP/P2Y12 Pathway Confers Additional Protection against Arterial Thrombosis in PAR-4 Deficient Mice

Ivo Cornelissen, Erica De Candia, Daniel Palmer, Shaun R Coughlin, MD, PhD

Blood (2008) 112 (11): 3933.

https://doi.org/10.1182/blood.V112.11.3933.3933

Published: 2008

Journal Articles

The Role of Gi Signaling in Hematopoiesis.

Marie Terpager, Hiroshi Kataoka, Ivo Cornelissen, Justin Hamilton, Shaun R Coughlin

Blood (2008) 112 (11): 1402.

https://doi.org/10.1182/blood.V112.11.1402.1402

Published: 2008

Journal Articles

Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin

Rashmi Sood, Lynette Sholl, Berend Isermann, Mark Zogg, Shaun R. Coughlin, Hartmut Weiler

Blood (2008) 112 (3): 585–591.

https://doi.org/10.1182/blood-2007-09-111302

Published: 2008

Includes: Supplemental data

Journal Articles

Protein Disulfide Isomerase Is Required for Fibrin Generation and Platelet Thrombus Formation In Vivo.

Jaehyung Cho, PhD, Barbara C. Furie, Ph.D., Shaun R. Coughlin, M.D./Ph.D., Bruce Furie, M.D.

Blood (2007) 110 (11): 292.

https://doi.org/10.1182/blood.V110.11.292.292

Published: 2007

Journal Articles

Mechanisms for Mortality Reduction by Activated Protein C in Severe Sepsis.

Edward J. Kerschen, PhD, Brian C. Cooley, PhD, Francis J. Castellino, PhD, Shaun R. Coughlin, MD, PhD, Jose A. Fernandez, MD, PhD, John H. Griffin, PhD, Hartmut Weiler, PhD

Blood (2006) 108 (11): 1.

https://doi.org/10.1182/blood.V108.11.1.1

Published: 2006

Journal Articles

Roles of protease-activated receptors in a mouse model of endotoxemia

Eric Camerer, Ivo Cornelissen, Hiroshi Kataoka, Daniel N. Duong, Yao-Wu Zheng, Shaun R. Coughlin

Blood (2006) 107 (10): 3912–3921.

https://doi.org/10.1182/blood-2005-08-3130

Published: 2006

Journal Articles

APC signaling: tickling PAR1 for barrier protection?

Eric Camerer, Shaun R. Coughlin

Blood (2005) 105 (8): 3004–3005.

https://doi.org/10.1182/blood-2005-01-0334

Published: 2005

Journal Articles

Protease-Activator Receptor 4 Is Required for Maximal Thrombus Growth, but Not for Fibrin Generation in Thrombi after Laser Injury.

Erik R. Vandendries, MD-PhD, Justin R. Hamilton, PhD, Shaun R. Coughlin, MD-PhD, Barbara C. Furie, PhD, Bruce Furie, MD

Blood (2004) 104 (11): 624.

https://doi.org/10.1182/blood.V104.11.624.624

Published: 2004

Journal Articles

Platelets, protease-activated receptors, and fibrinogen in hematogenous metastasis

Eric Camerer, Aisha A. Qazi, Daniel N. Duong, Ivo Cornelissen, Rommel Advincula, Shaun R. Coughlin

Blood (2004) 104 (2): 397–401.

https://doi.org/10.1182/blood-2004-02-0434

Published: 2004

Journal Articles

Combined deficiency of protease-activated receptor-4 and fibrinogen recapitulates the hemostatic defect but not the embryonic lethality of prothrombin deficiency

Eric Camerer, Daniel N. Duong, Justin R. Hamilton, Shaun R. Coughlin

Blood (2004) 103 (1): 152–154.

https://doi.org/10.1182/blood-2003-08-2707

Published: 2004

Journal Articles

Protease-activated receptors 1 and 4 mediate thrombin signaling in endothelial cells

Hiroshi Kataoka, Justin R. Hamilton, David D. McKemy, Eric Camerer, Yao-Wu Zheng, Abby Cheng, Courtney Griffin, Shaun R. Coughlin

Blood (2003) 102 (9): 3224–3231.

https://doi.org/10.1182/blood-2003-04-1130

Published: 2003

Journal Articles

Protection against thrombosis in mice lacking PAR3

Ethan J. Weiss, Justin R. Hamilton, Katy E. Lease, Shaun R. Coughlin

Blood (2002) 100 (9): 3240–3244.

https://doi.org/10.1182/blood-2002-05-1470

Published: 2002

Journal Articles

Glycoprotein V-Deficient Platelets Have Undiminished Thrombin Responsiveness and Do Not Exhibit a Bernard-Soulier Phenotype

Mark L. Kahn, Thomas G. Diacovo, Dorothy F. Bainton, Francois Lanza, JoAnn Trejo, Shaun R. Coughlin

Blood (1999) 94 (12): 4112–4121.

https://doi.org/10.1182/blood.V94.12.4112

Published: 1999

NARROW

Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense

Identification of a Racially Dimorphic Variant in the Human Platelet PAR4 Thrombin Receptor Altering Platelet Function and Pharmacologic Inhibition

TMEM16F Ion Channel Regulates Calcium-Dependent PS Exposure, Hemostasis, and Thrombosis

Carcinoma mucins trigger reciprocal activation of platelets and neutrophils in a murine model of Trousseau syndrome

Gi-Coupled GPCR Signaling Is Required at Multiple Levels and In Different Lineages In Hematopoiesis.

Endothelial and Hematopoietic Tissue Factor Are Unnecessary in Two Mouse Models of Hemostasis and Thrombosis

GP-VI Disruption Confers Additional Protection against Arterial Thrombosis in PAR-4 Deficient Mice

Inhibition of the ADP/P2Y12 Pathway Confers Additional Protection against Arterial Thrombosis in PAR-4 Deficient Mice

The Role of Gi Signaling in Hematopoiesis.

Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin

Protein Disulfide Isomerase Is Required for Fibrin Generation and Platelet Thrombus Formation In Vivo.

Mechanisms for Mortality Reduction by Activated Protein C in Severe Sepsis.

Roles of protease-activated receptors in a mouse model of endotoxemia

APC signaling: tickling PAR1 for barrier protection?

Protease-Activator Receptor 4 Is Required for Maximal Thrombus Growth, but Not for Fibrin Generation in Thrombi after Laser Injury.

Platelets, protease-activated receptors, and fibrinogen in hematogenous metastasis

Combined deficiency of protease-activated receptor-4 and fibrinogen recapitulates the hemostatic defect but not the embryonic lethality of prothrombin deficiency

Protease-activated receptors 1 and 4 mediate thrombin signaling in endothelial cells

Protection against thrombosis in mice lacking PAR3

Glycoprotein V-Deficient Platelets Have Undiminished Thrombin Responsiveness and Do Not Exhibit a Bernard-Soulier Phenotype

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American Society of Hematology

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ASH Publications

American Society of Hematology

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