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Journal Articles

Luspatercept for the Treatment of Anemia in Non-Transfusion-Dependent β-Thalassemia: Final Safety and Efficacy Data from the BEYOND Trial

Ali T Taher, Vip Viprakasit, Antonis Kattamis, Silverio Perrotta, Paolo Ricchi, John B. Porter, Thomas D Coates, Gian Luca Forni, Khaled M. Musallam, Oriana Esposito, Ana Carolina Giuseppi, Wen-Ling Kuo, Marta Reverte, Richard Wei, Luciana Moro Bueno, Maria Domenica Cappellini

Blood (2023) 142 (Supplement 1): 3847.

https://doi.org/10.1182/blood-2023-174097

Published: 2023

Journal Articles

The Areal Project: How Virtual Reality Application Could Enhance Patient's Quality Time during Transfusion Therapy in Adult Patients with Thalassemia and Sickle Cell Disease

Valentino Megale, Maddalena Casale, Raffaella Colombatti, Valeria Pinto, Ilaria Baido, Cristina Brentan, Gian Luca Forni, Miriam Forte, Barbara Gianesin, Francesca Grieco, Elizabeth Maran, Vania Munaretto, Silverio Perrotta, Maria Caterina Putti, Giacomo Robello

Blood (2022) 140 (Supplement 1): 13049–13050.

https://doi.org/10.1182/blood-2022-165189

Published: 2022

Journal Articles

Premature aging of the immune system affects the response to SARS-CoV-2 mRNA vaccine in β-thalassemia: role of an additional dose

Blood (2022) 140 (15): 1735–1738.

https://doi.org/10.1182/blood.2022017594

Published: 2022

Includes: Supplemental data

Journal Articles

Hemoglobinopathies and Cancer: Preliminary Results of an Italian Multicenter Experience

Raffaella Origa, Filomena Longo, Rosario Di Maggio, Elena Cassinerio, Valeria Maria Pinto, Antonella Quarta, Maddalena Casale, Barbara Gianesin, Susanna Barella, Andrea Piolatto, Aurelio Maggio, Giovanna Graziadei, Claudia Romano, Silverio Perrotta, Gian Luca Forni

Blood (2021) 138 (Supplement 1): 946.

https://doi.org/10.1182/blood-2021-147710

Published: 2021

Journal Articles

Longitudinal Effect of Luspatercept Treatment on Iron Overload and Iron Chelation Therapy (ICT) in Adult Patients (Pts) with β-Thalassemia in the Believe Trial

Olivier Hermine, Maria Domenica Cappellini, Ali T. Taher, Thomas D. Coates, MD, Vip Viprakasit, Ersi Voskaridou, Ashutosh Lal, MD, Hong Keng Liew, Silverio Perrotta, Abderrahim Khelif, Antonis Kattamis, Jeevan K. Shetty, George Zhang, Yu (Olivia) Tian, Dimana Miteva, Tatiana Zinger, Derek Tang, Jay T. Backstrom, John B. Porter, MA, MD, FRCP, FRCPath

Blood (2020) 136 (Supplement 1): 47–48.

https://doi.org/10.1182/blood-2020-136517

Published: 2020

Journal Articles

Influenza Vaccination in Asplenia: Improving Quality of Care in Time of Coronavirus

Nicoletta Di Maio, Giovanna Russo, Susanna Barella, MD, Gian Luca Forni, MD, Raffaella Colombatti, MDPhD, Lucia Notarangelo, Giovanna Graziadei, MD, Antonella Sau, MD, Luciana Rigoli, Piero Farruggia, Saveria Campisi, MD, Tommaso Casini, Manuela Balocco, MD, Gianluca Boscarol, Ilaria Capolsini, MD, Paolo Grotto, MD, Fiorina Giona, MD, Ilaria Lazzareschi, MD, Pellegrina Pugliese, MD, Francesca Fioredda, PhD, Silvia Fasoli, Maria Caterina Putti, MD, Maddalena Migliavacca, MD PhD, Corti Paola, MD, Serena Tripodi, MD, Paola Saracco, MD, Simone Ferrero, MD, Assunta Tornesello, MD, Marilena Serra, MD, Saverio Ladogana, MD, Giovanni Palazzi, MD, Federico Verzegnassi, MD, Carlo Baronci, MD, Giuseppe Palumbo, MD, Simone Cesaro, MD, Laura Sainati, MD, Flavia Rivellini, MD, Rosanna Di Concilio, MD, Vania Munaretto, MD, Elena Facchini, MD, Paola Giordano, MD, Maria Grazia Sanna, Silverio Perrotta, MD, Maddalena Casale, MD PhD

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-142335

Published: 2020

Journal Articles

An Educational Study Promoting the Delivery of TCD Screening in Paediatric Sickle Cell Disease: A European Multi-Centre Perspective

Baba PD Inusa, MD, Corrina Macmahon, MD, Laura Sainati, MD, Raffaella Colombatti, MD PhD, Maddalena Casale, MD PhD, Patrizia Rampazzo, MD, Silverio Perrotta, Soundrie Padayachee

Blood (2019) 134 (Supplement_1): 2172.

https://doi.org/10.1182/blood-2019-130390

Published: 2019

Journal Articles

Evaluating Luspatercept Responders in the Phase 3, Randomized, Double-Blind, Placebo-Controlled BELIEVE Trial of Luspatercept in Adult Beta-Thalassemia Patients (Pts) Who Require Regular Red Blood Cell (RBC) Transfusions

Blood (2019) 134 (Supplement_1): 3545.

https://doi.org/10.1182/blood-2019-122685

Published: 2019

Journal Articles

An Analysis of Racial and Ethnic Backgrounds within the Casire International Cohort of Sickle Cell Disease Patients: Implications for Disease Phenotype and Clinical Research

Blood (2019) 134 (Supplement_1): 2305.

https://doi.org/10.1182/blood-2019-127613

Published: 2019

Journal Articles

Effects of Luspatercept on Iron Overload and Impact on Responders to Luspatercept: Results from the BELIEVE Trial

John Porter, Maria Domenica Cappellini, MD, Thomas Coates, MD, Olivier Hermine, Vip Viprakasit, MD DPhil, Ersi Voskaridou, Hong Keng Liew, Silverio Perrotta, Abderrahim Khelif, Antonis Kattamis, Abderrahmane Laadem, Jeevan K. Shetty, Wen-Ling Kuo, Dimana Miteva, Tatiana Zinger, Peter G. Linde, Daniel Sinsimer, Ali Taher

Blood (2019) 134 (Supplement_1): 2245.

https://doi.org/10.1182/blood-2019-122561

Published: 2019

Journal Articles

Retrospective and Prospective Study of Childhood Autoimmune Hemolytic Anemia. a Preliminary Report from the Red Cell Working Group of the Paediatric Hemato-Oncology Italian Associations (AIEOP)

Blood (2019) 134 (Supplement_1): 947.

https://doi.org/10.1182/blood-2019-124735

Published: 2019

Journal Articles

Luspatercept improves hemoglobin levels and blood transfusion requirements in a study of patients with β-thalassemia

Antonio Piga, Silverio Perrotta, Maria Rita Gamberini, Ersi Voskaridou, Angela Melpignano, Aldo Filosa, Vincenzo Caruso, Antonello Pietrangelo, Filomena Longo, Immacolata Tartaglione, Caterina Borgna-Pignatti, Xiaosha Zhang, Abderrahmane Laadem, Matthew L. Sherman, Kenneth M. Attie

Blood (2019) 133 (12): 1279–1289.

https://doi.org/10.1182/blood-2018-10-879247

Published: 2019

Includes: Supplemental data

Journal Articles

The Believe Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept in Adult Beta-Thalassemia Patients Who Require Regular Red Blood Cell (RBC) Transfusions

Blood (2018) 132 (Supplement 1): 163.

https://doi.org/10.1182/blood-2018-163

Published: 2018

Journal Articles

Cognitive, Brain and Intracranial Artery Involvement in Beta Thalassemia

Blood (2017) 130 (Supplement 1): 3506.

https://doi.org/10.1182/blood.V130.Suppl_1.3506.3506

Published: 2017

Journal Articles

Gene Therapy for Beta Thalassemia: Preliminary Results from the PHASE I/II Tiget-Bthal Trial of Autologous Hematopoietic Stem Cells Genetically Modified with GLOBE Lentiviral Vector

Blood (2017) 130 (Supplement 1): 355.

https://doi.org/10.1182/blood.V130.Suppl_1.355.355

Published: 2017

Journal Articles

Use of Next Generation Sequencing Panel to Clarify Undiagnosed Cases of Hereditary Hemolytic Anemias

Elisa Fermo, PhD, Cristina Vercellati, PhD, Anna Paola Marcello, PhD, Ebru Yilmaz Keskin, MD, Aurora Feliu Torres, MD, Silverio Perrotta, Tekin Aksu, MD, Anna Zaninoni, BS, Valentina Brancaleoni, MSc, Richard van Wijk, PhD, Sultan Aydin Koker, MD, Alberto Zanella, MD, Agostino Cortelezzi, Prof, Wilma Barcellini, MD, Paola Bianchi, BSc, PhD

Blood (2017) 130 (Supplement 1): 3480.

https://doi.org/10.1182/blood.V130.Suppl_1.3480.3480

Published: 2017

Journal Articles

New Film-Coated Tablet Formulation of Deferasirox Is Well Tolerated in Patients with Thalassemia or MDS: Results of the Randomized, Phase II E.C.L.I.P.S.E. Study

Ali T. Taher, MD PhD, Raffaella Origa, Silverio Perrotta, Alexandra Kouraklis, Giovan Battista Ruffo, Antonis Kattamis, MD, Ai-Sim Goh, Annelore Cortoos, Vicky Huang, Marine Weill, Raquel Merino Herranz, John B. Porter, BA MB BChir MRCP(Path) FRCP(Path) MD

Blood (2016) 128 (22): 1285.

https://doi.org/10.1182/blood.V128.22.1285.1285

Published: 2016

Journal Articles

History of Asthma is Associated with Albuminuria within an International Pediatric Cohort of Sickle Cell Disease Patients: A Casire Group Analysis

Immacolata Tartaglione, MD, Baba PD Inusa, MBBS, FMCPaed, FRCPCH, MRCP, DCP, Raffaella Colombatti, MD PhD, Deepa Manwani, MD, Silverio Perrotta, Eugenia Vicky Naa Kwarley Asare, MBChB, BSc, Connie M. Piccone, MD, Fredericka Sey, MB ChB, Charles Antwi-Boasiako, PhD, Laura Sainati, MD, Adetola A. Kassim, MD MS, Donna Boruchov, MD, Angela Rivers, MD PhD, William Zempsky, MD, Crawford John Strunk, MD, Biree Andemariam, MD, Andrew D. Campbell, MD

Blood (2016) 128 (22): 3668.

https://doi.org/10.1182/blood.V128.22.3668.3668

Published: 2016

Journal Articles

Improved Patient-Reported Outcomes with a Film-Coated Versus Dispersible Tablet Formulation of Deferasirox: Results from the Randomized, Phase II E.C.L.I.P.S.E. Study

Blood (2016) 128 (22): 850.

https://doi.org/10.1182/blood.V128.22.850.850

Published: 2016

Journal Articles

Luspatercept (ACE-536) Reduces Disease Burden, Including Anemia, Iron Overload, and Leg Ulcers, in Adults with Beta-Thalassemia: Results from a Phase 2 Study

Antonio Piga, MD, Silverio Perrotta, MD, M.Rita Gamberini, MD, Ersi Voskaridou, MD, Angela Melpignano, Aldo Filosa, MD, Antonello Pietrangelo, MD, Vincenzo Caruso, MD, Gian Luca Forni, MD, Xiaosha Zhang, Ashley Bellevue, Dawn Wilson, Abderrahmane Laadem, MD, Matthew L. Sherman, MD, Kenneth M. Attie, MD

Blood (2015) 126 (23): 752.

https://doi.org/10.1182/blood.V126.23.752.752

Published: 2015

NARROW

Luspatercept for the Treatment of Anemia in Non-Transfusion-Dependent β-Thalassemia: Final Safety and Efficacy Data from the BEYOND Trial

The Areal Project: How Virtual Reality Application Could Enhance Patient's Quality Time during Transfusion Therapy in Adult Patients with Thalassemia and Sickle Cell Disease

Premature aging of the immune system affects the response to SARS-CoV-2 mRNA vaccine in β-thalassemia: role of an additional dose

Hemoglobinopathies and Cancer: Preliminary Results of an Italian Multicenter Experience

Longitudinal Effect of Luspatercept Treatment on Iron Overload and Iron Chelation Therapy (ICT) in Adult Patients (Pts) with β-Thalassemia in the Believe Trial

Influenza Vaccination in Asplenia: Improving Quality of Care in Time of Coronavirus

An Educational Study Promoting the Delivery of TCD Screening in Paediatric Sickle Cell Disease: A European Multi-Centre Perspective

Evaluating Luspatercept Responders in the Phase 3, Randomized, Double-Blind, Placebo-Controlled BELIEVE Trial of Luspatercept in Adult Beta-Thalassemia Patients (Pts) Who Require Regular Red Blood Cell (RBC) Transfusions

An Analysis of Racial and Ethnic Backgrounds within the Casire International Cohort of Sickle Cell Disease Patients: Implications for Disease Phenotype and Clinical Research

Effects of Luspatercept on Iron Overload and Impact on Responders to Luspatercept: Results from the BELIEVE Trial

Retrospective and Prospective Study of Childhood Autoimmune Hemolytic Anemia. a Preliminary Report from the Red Cell Working Group of the Paediatric Hemato-Oncology Italian Associations (AIEOP)

Luspatercept improves hemoglobin levels and blood transfusion requirements in a study of patients with β-thalassemia

The Believe Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept in Adult Beta-Thalassemia Patients Who Require Regular Red Blood Cell (RBC) Transfusions

Cognitive, Brain and Intracranial Artery Involvement in Beta Thalassemia

Gene Therapy for Beta Thalassemia: Preliminary Results from the PHASE I/II Tiget-Bthal Trial of Autologous Hematopoietic Stem Cells Genetically Modified with GLOBE Lentiviral Vector

Use of Next Generation Sequencing Panel to Clarify Undiagnosed Cases of Hereditary Hemolytic Anemias

New Film-Coated Tablet Formulation of Deferasirox Is Well Tolerated in Patients with Thalassemia or MDS: Results of the Randomized, Phase II E.C.L.I.P.S.E. Study

History of Asthma is Associated with Albuminuria within an International Pediatric Cohort of Sickle Cell Disease Patients: A Casire Group Analysis

Improved Patient-Reported Outcomes with a Film-Coated Versus Dispersible Tablet Formulation of Deferasirox: Results from the Randomized, Phase II E.C.L.I.P.S.E. Study

Luspatercept (ACE-536) Reduces Disease Burden, Including Anemia, Iron Overload, and Leg Ulcers, in Adults with Beta-Thalassemia: Results from a Phase 2 Study

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American Society of Hematology

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