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Journal Articles

Challenges in  hemoglobinopathy control programs: Insights from Türkiye

Free
Yesim Aydinok, Alphan Kupesiz, Burcak Tatli Gunes, Ayse Gonca Kacar, Dilber Talia Ileri, Hamiyet Hekimci Ozdemir, Ayca Yozgat, Mehtap Ertekin, Huseyin Tokgoz, Melike Evim, Elif Kazanci, Ayse Simsek, Sule Unal, Selma Unal, Alper Ozcan, Suheyla Ocak, Mustafa Cemaloglu, Sultan Aydın, Nazan Sarper, Can Acipayam, Ozcan Bor, Hale Oren, Nihal Karadas, Funda Kupesiz, Yesim Yigit, Nihal Boz, Ahmet Koc, Sinan Akbayram, Mehmet Fatih Orhan, Murat Soker, Defne Ay Tuncel, Mediha Akcan, Nurettin Okur, Canan Albayrak, Ozlem Gul Kirkas, Fatih Azik, Tuba Nur Tahtakesen Gucer, Kamuran Karaman, Emine Turkkan, Sifa Sahin, Ali Fettah, Aylin Canbolat, Arzu Akyay, Huseyin Gulen, Meryem Albayrak, Yilmaz Ay, Zeynep Karakas
Journal: Blood
Blood (2025) 146 (Supplement 1): 4693.
https://doi.org/10.1182/blood-2025-4693
Published: 2025
Journal Articles

Disease monitoring and management among pediatric patients with pyruvate kinase deficiency: Real-world practices from pyruvate kinase deficiency registries prior to 2024 international expert guidelines

Free
Sule Unal, Stefan W. Eber, Andreas Glenthoej, Bertil Glader, Eduard Van Beers, Rachael Grace, Joan-Lluis Vives Corrons, Hitoshi Kanno, Kevin Kuo, Paola Bianchi, Bryan McGee, Yan (Flame) Yan, Audra Boscoe, Junlong Li, Janet Ford, Carl Lander
Journal: Blood
Blood (2025) 146 (Supplement 1): 4454.
https://doi.org/10.1182/blood-2025-4454
Published: 2025
Journal Articles

Congenital factor II deficiency presenting with recurrent thrombosis

Free
Gamze Gürsoy Özçelik, Emre Yaman, Rahşan Göçmen, Sinan Balcı, Halil Öge, Tekin Aksu, Sule Unal, Dilek Yalnızoğlu, Selin Aytaç Eyüpoğlu
Journal: Blood
Blood (2025) 146 (Supplement 1): 1307.
https://doi.org/10.1182/blood-2025-1307
Published: 2025
Journal Articles

Morbidities in β-thalassemia intermedia across the spectrum of disease severity: A nationwide study in Türkiye

Free
Yesim Aydinok, Zeynep Karakas, Ali Aycicek, Burcak Tatli Gunes, Mehmet Ertem, Yesim Oymak, Nur Akad Soyer, Selma Unal, Alper Ozcan, Sule Unal, Yeter Duzenli, Nilgun Sayinalp, Volkan Karakus, Emel Gurkan, Huseyin Tokgoz, Nihal Karadas, Burcu Akinci, Ayse Hilal Eroglu Kucukdiller, Ozcan Bor, Aysun Yikilmaz, Seda Aras, Bahar Sevgili, Fatma Aykas, Can Acipayam, Sultan Okur Acar, Nazan Sarper, Unal Atas, Basak Unver Koluman, Serkan Guven, İpek Yildiz, Seda Yilmaz, Naci Tiftik, Nevin Aslan, Utku Aygunes, Guchan Alanoglu, Idris Ince, Vahap Okan, Fatos Dilan Koseoglu, Bilal Aygun, O. Alphan Kupesiz
Journal: Blood
Blood (2025) 146 (Supplement 1): 1138.
https://doi.org/10.1182/blood-2025-1138
Published: 2025
Journal Articles

Drug-Induced Diabetes during Treatment of ALL in Children: Who Is at Risk and When?

Free
Fatma Gül Ersan, Hulya Yilmaz, Cagri Coskun, Gizem Cilsaat, Dogus Vuralli Karaoglan, Baris Kuskonmaz, Zeynep Alev Özön, Sule Unal, Selin Aytac, Elmas Nazli Gonc
Journal: Blood
Blood (2024) 144 (Supplement 1): 5853.
https://doi.org/10.1182/blood-2024-199258
Published: 2024
Journal Articles

Analysis of Durability of Response to Avatrombopag (AVA) from a Phase 3b Multicenter, Randomized, Double-Blind, Placebo (PBO)-Controlled, Parallel-Group Trial to Evaluate the Efficacy and Safety of AVA for the Treatment of Pediatric Patients with Immune Thrombocytopenia

Free
Rachael F. Grace, Goksel Leblebisatan, Yesim Aydinok, Sule Unal, John D. Grainger, Jessica Zhang, Brian Jamieson, Scott Kolodny
Journal: Blood
Blood (2024) 144 (Supplement 1): 1191.
https://doi.org/10.1182/blood-2024-205431
Published: 2024
Journal Articles

Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis

Free
Samuel C. C. Chiang, Laura E. Covill, Bianca Tesi, Tessa M. Campbell, Heinrich Schlums, Jelve Nejati-Zendegani, Karina Mördrup, Stephanie Wood, Jakob Theorell, Takuya Sekine, Waleed Al-Herz, Himmet Haluk Akar, Fatma Burcu Belen, Mei Yoke Chan, Omer Devecioglu, Tekin Aksu, Marianne Ifversen, Iwona Malinowska, Magnus Sabel, Ekrem Unal, Sule Unal, Wendy J. Introne, Konrad Krzewski, Kimberly C. Gilmour, Stephan Ehl, Hans-Gustaf Ljunggren, Magnus Nordenskjöld, AnnaCarin Horne, Jan-Inge Henter, Marie Meeths, Yenan T. Bryceson
Journal: Blood
Blood (2024) 144 (8): 873–887.
https://doi.org/10.1182/blood.2024024499
Published: 2024
Includes: Supplemental data
Journal Articles

A Single-Center Large Cohort of Chronic Neutropenia Patients and a Model for Estimation of Congenital Neutropenias

Free
Ugur Erkin Zeytinoglu, Fatma Gumruk, Sule Unal Cangul
Journal: Blood
Blood (2023) 142 (Supplement 1): 2541.
https://doi.org/10.1182/blood-2023-189775
Published: 2023
Journal Articles

HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia

Open Access
Marie-Françoise O’Donohue, Lydie Da Costa, Marco Lezzerini, Sule Unal, Clément Joret, Marije Bartels, Eva Brilstra, Marijn Scheijde-Vermeulen, Ludivine Wacheul, Kim De Keersmaecker, Stijn Vereecke, Veerle Labarque, Manon Saby, Sophie D. Lefevre, Jessica Platon, Nathalie Montel-Lehry, Nathalie Laugero, Eric Lacazette, Koen van Gassen, Riekelt H. Houtkooper, Pelin Ozlem Simsek-Kiper, Thierry Leblanc, Nese Yarali, Arda Cetinkaya, Nurten A. Akarsu, Pierre-Emmanuel Gleizes, Denis L. J. Lafontaine, Alyson W. MacInnes
Journal: Blood
Blood (2022) 139 (21): 3111–3126.
https://doi.org/10.1182/blood.2021011846
Published: 2022
Includes: Supplemental data
Journal Articles

A randomized, placebo-controlled, double-blind trial of canakinumab in children and young adults with sickle cell anemia

Free
Clinical Trials & Observations
David C. Rees, Yurdanur Kilinc, Selma Unal, Carlton Dampier, Betty S. Pace, Banu Kaya, Sara Trompeter, Isaac Odame, Johnny Mahlangu, Sule Unal, Julie Brent, Regine Grosse, Beng R. Fuh, Baba P. D. Inusa, Ariel Koren, Goksel Leblebisatan, Carina Levin, Elizabeth McNamara, Karin Meiser, Douglas Hom, Stephen J. Oliver
Journal: Blood
Blood (2022) 139 (17): 2642–2652.
https://doi.org/10.1182/blood.2021013674
Published: 2022
Includes: Supplemental data
Journal Articles

Isolated CNS Hemophagocytic Lymphohistiocytosis in Children:What We Know, What We Don't Know ?

Free
Selin Aytac, Gunay Balta, Baris Kuskonmaz, Tekin Aksu, Fatma Visal Okur, Sule Unal, Duygu Uckan, Fatma Gumruk
Journal: Blood
Blood (2021) 138 (Supplement 1): 4190.
https://doi.org/10.1182/blood-2021-153509
Published: 2021
Journal Articles

The Outcome of Modified St. Jude Total XV Protocol in Turkish Children with Newly Diagnosed Acute Lymphoblastic Leukemia

Free
Hulya Yilmaz, MD, Selin Aytac, MD, Barış Kuşkonmaz, MD, Duygu Çetinkaya, MD, Sule Unal, MD, Fatma Gumruk, MD, Mualla Çetin, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2590.
https://doi.org/10.1182/blood-2019-130163
Published: 2019
Journal Articles

Pyruvate Kinase Deficiency Cases Mimicking Congenital Dyserythropoietic Anemia

Free
Sule Unal, MD, Tekin Aksu, MD, Cagrı Coskun, MD, Fatma Gumruk, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4794.
https://doi.org/10.1182/blood-2019-124272
Published: 2019
Journal Articles

Double-Blind, Randomized Study of Canakinumab Treatment in Pediatric and Young Adult Patients with Sickle Cell Anemia

Free
David C Rees, Yurdanur Kilinc, MD, Selma Unal, Carlton Dampier, MD, Betty S. Pace, MD, Banu Kaya, MD, Sara Trompeter, MBChB BSc MRCPCH FRCPath MSc, Isaac Odame, Johnny N Mahlangu, MBBCH, MMed, FCPath, Sule Unal, MD, Julie Brent, MD, Regine Grosse, MD, Beng R. Fuh, MD, Baba PD Inusa, MD, Ariel Koren, MD, Carina Levin, MD PhD, Steven Mortier, Elizabeth McNamara, Yue Li, Stephen John Oliver, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 615.
https://doi.org/10.1182/blood-2019-123355
Published: 2019
Journal Articles

Influence of Paroxysmal Nocturnal Hemoglobinuria Clone Positivity on Outcome of Childhood Acquried Aplastic Anemia: A Multicenter Center Study

Free
Sule Unal Cangul, Deniz Yilmaz Karapinar, Arzu Yazal Erdem, Husniye Nese Yarali, Hamiyet Hekimci Ozdemir, Fatma Gumruk, MD, Hasan Fatih Cakmakli, MD, Elif Unal Ince, Gul Nihal Nihal Ozdemir, MD, Muge Gokce, MD, Tiraje Celkan, MD, Aysenur Bahadir, Turan Bayhan, MD, Hale Oren, Huseyin Gulen, Funda Tayfun Kupesiz, Mualla Cetin, Namik Ozbek
Journal: Blood
Blood (2018) 132 (Supplement 1): 5101.
https://doi.org/10.1182/blood-2018-99-118858
Published: 2018
Journal Articles

Children with Juvenile Myelomonocytic Leukemia (JMML); A Single Center Experience

Free
Özlem Satirer, MD, Selin Aytac, Baris Kuskonmaz, MD, Sule Unal, Fatma Gumruk, MD, Charlotte Niemeyer, MD, Mualla Cetin
Journal: Blood
Blood (2018) 132 (Supplement 1): 5527.
https://doi.org/10.1182/blood-2018-99-119585
Published: 2018
Journal Articles

Diamond-Blackfan Anemia Phenotype Caused By Deficiency of Adenosine Deaminase 2

Free
Enikoe Amina Szvetnik, Christian Klemann, Ina Hainmann, Marie-Francoise O'-Donohue, Tamás Farkas, Marena Niewisch, Regine Grosse, MD, Gabriele Escherich, MD, Sule Unal, Naz Guleray, Muge Gokce, Lydie Da Costa, Thierry LeBlanc, MD, Hélène Dollfus, Eusebia Lara-Villacanas, Thomas Wiesel, Victor Pastor Loyola, MSc, Sushree Sangita Sahoo, M.Sc., Doris Steinemann, PhD, Myriam Lorenz, Klaus Schwarz, Stephan Ehl, Michael Hershfield, Pierre-Emmanuel Gleizes, Charlotte M. Niemeyer, MD, Alyson W. MacInnes, Marcin W. Wlodarski, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 874.
https://doi.org/10.1182/blood.V130.Suppl_1.874.874
Published: 2017
Journal Articles

Endocrinological Abnormalities Among Adult Thallasemic Patients

Free
Sule Unal Cangul, Mufide Okay, Ugur Unluturk, Seda B. Oguz, Mualla Cetin, Fatma Gumruk, MD, Nilgun Sayinalp, MD, Inci Bajin
Journal: Blood
Blood (2017) 130 (Supplement 1): 2218.
https://doi.org/10.1182/blood.V130.Suppl_1.2218.2218
Published: 2017
Journal Articles

Long-Term Outcome of Deferasirox Chelation in Patients with Thalassemia Major

Free
Sule Unal, Neslihan Kalkan, Mualla Cetin, Prof. Dr., Fatma Gumruk
Journal: Blood
Blood (2016) 128 (22): 3620.
https://doi.org/10.1182/blood.V128.22.3620.3620
Published: 2016
Journal Articles

Infant Lymphoblastic Leukemia: A Single Center Experience

Free
Selin Aytac, Inci Yaman Bajin, Barış Kuşkonmaz, Duygu Uckan-Cetinkaya, Ilhan Altan, Sule Unal, Betül Tavil, Fatma Gumruk, A. Murat Tuncer, MD, Mualla Cetin, Prof. Dr.
Journal: Blood
Blood (2016) 128 (22): 5161.
https://doi.org/10.1182/blood.V128.22.5161.5161
Published: 2016