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Journal Articles

Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma

Bruno M. Grande, Daniela S. Gerhard, Aixiang Jiang, Nicholas B. Griner, Jeremy S. Abramson, Thomas B. Alexander, Hilary Allen, Leona W. Ayers, Jeffrey M. Bethony, Kishor Bhatia, Jay Bowen, Corey Casper, John Kim Choi, Luka Culibrk, Tanja M. Davidsen, Maureen A. Dyer, Julie M. Gastier-Foster, Patee Gesuwan, Timothy C. Greiner, Thomas G. Gross, Benjamin Hanf, Nancy Lee Harris, Yiwen He, John D. Irvin, Elaine S. Jaffe, Steven J. M. Jones, Patrick Kerchan, Nicole Knoetze, Fabio E. Leal, Tara M. Lichtenberg, Yussanne Ma, Jean Paul Martin, Marie-Reine Martin, Sam M. Mbulaiteye, Charles G. Mullighan, Andrew J. Mungall, Constance Namirembe, Karen Novik, Ariela Noy, Martin D. Ogwang, Abraham Omoding, Jackson Orem, Steven J. Reynolds, Christopher K. Rushton, John T. Sandlund, Roland Schmitz, Cynthia Taylor, Wyndham H. Wilson, George W. Wright, Eric Y. Zhao, Marco A. Marra, Ryan D. Morin, Louis M. Staudt

Blood (2019) 133 (12): 1313–1324.

https://doi.org/10.1182/blood-2018-09-871418

Published: 2019

Includes: Supplemental data

Journal Articles

Burkitt Lymphoma Genome Sequencing Project (BLGSP): Integrative Genomic and Transcriptomic Characterization of Burkitt Lymphoma

Blood (2017) 130 (Supplement 1): 39.

https://doi.org/10.1182/blood.V130.Suppl_1.39.39

Published: 2017

Journal Articles

Discovery and Validation of Cell-Surface Protein Mesothelin (MSLN) As a Novel Therapeutic Target in AML: Results from the COG/NCI Target AML Initiative

Blood (2016) 128 (22): 2873.

https://doi.org/10.1182/blood.V128.22.2873.2873

Published: 2016

Journal Articles

Burkitt Lymphoma Genome Sequencing Project (BLGSP): Introduction

Daniela S Gerhard, PhD, Bruno Grande, B. Sc., Nicholas Griner, PhD, Corey Casper, MD, Sarah E. Gerdts, MPH, Abraham Omoding, MD, Jackson Orem, MD, Sam M Mbulaiteye, MD, Martin D. Ogwang, MD, Steven J. Reynolds, MD MPH, Kishor Bhatia, PhD, Leona Ayers, MD, John K Choi, MD, Charles G. Mullighan, MBBS, MSc, PhD, John T. Sandlund, MD, Thomas B. Alexander, MD MPH, Jeremy S. Abramson, MD, Thomas G. Gross, MD PhD, Ariela Noy, MD PhD, Jeffrey Bethony, PhD, Fabio Leal, MD, PhD, Timothy C Greiner, MS, MD, Elaine S. Jaffe, MD, Nancy Lee Harris, MD, Julie M. Gastier-Foster, PhD, Jay Bowen, MS, Benjamin Hanf, Roland Schmitz, PhD, Jean-Paul Martin, MD, Marie-Reine Martin, MD, John D. Irvin, MD PhD, Ellen Miller, MS, Patee Gesuwan, Leandro C. Hermida, Tanja M. Davidsen, PhD, Andrew J. Mungall, Yussanne Ma, PhD, Marco A. Marra, PhD, Ryan D. Morin, Louis M. Staudt, MD PhD

Blood (2016) 128 (22): 1760.

https://doi.org/10.1182/blood.V128.22.1760.1760

Published: 2016

Journal Articles

Marked Differences in the Genomic Landscape of Pediatric Compared to Adult Acute Myeloid Leukemia: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative

Jason E Farrar, MD, Hamid Bolouri, PhD, Rhonda E. Ries, MA, Timothy Junius Triche, Jr., PhD, Emilia L. Lim, PhD, Todd A. Alonzo, PhD, Yussanne Ma, PhD, Richard Moore, PhD, Andrew J. Mungall, Marco A. Marra, PhD, Jaime Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Soheil Meshinchi

Blood (2016) 128 (22): 595.

https://doi.org/10.1182/blood.V128.22.595.595

Published: 2016

Journal Articles

Divergent Epigenomes in Pediatric and Adult Acute Myeloid Leukemia Implicate Cell of Origin and Transcriptional Silencing of Immune Responses As Sources of Clinically Relevant Heterogeneity: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative

Blood (2016) 128 (22): 1046.

https://doi.org/10.1182/blood.V128.22.1046.1046

Published: 2016

Journal Articles

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia

Thomas B. Alexander, MD MPH, Zhaohui Gu, PhD, John K Choi, MD, Mignon L. Loh, MD, John Horan, MD MPH, Barbara Buldini, MD, Giuseppe Basso, Sarah Elitzur, MD, C. Michel Zwaan, MD PhD, Valerie de Haas, MD PhD, Allen Eng Juh Yeoh, MD, Dirk Reinhardt, MD PhD, Daisuke Tomizawa, MD, PhD, Tim Lammens, Barbara De Moerloose, MD, Li Zhou, PhD, Hiroki Hori, MD PhD, Anthony V. Moorman, PhD, Andrew S. Moore, MBBS FRACP PhD, Ondrej Hrusak, MD PhD, Soheil Meshinchi, MD PhD, Etan Orgel, MD MS, Meenakshi Devidas, PhD, Stephen P. Hunger, MD, Jamie M Guidry Auvil, Malcolm A. Smith, MD PhD, Tanja M. Davidsen, PhD, Leandro C. Hermida, Patee Gesuwan, Marco A. Marra, PhD, Yussanne Ma, PhD, Andrew J. Mungall, Richard Moore, PhD, Daniela S. Gerhard, PhD, Xueyuan Cao, Lei Shi, PhD, Stanley Pounds, PhD, Hiroto Inaba, MD PhD, Charles Mullighan, MBBS, MSc, MD

Blood (2016) 128 (22): 454.

https://doi.org/10.1182/blood.V128.22.454.454

Published: 2016

Journal Articles

CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML

Blood (2016) 127 (24): 3094–3098.

https://doi.org/10.1182/blood-2016-04-709899

Published: 2016

Includes: Supplemental data

Journal Articles

TET2 Mutations Are Highly Associated with RUNX1-RUNX1T1 Translocations and NPMc+ in Childhood AML: a Report from Children's Oncology Group AAML03P1, AAML0531 and NCI/COG Target AML Initiative

Blood (2015) 126 (23): 1368.

https://doi.org/10.1182/blood.V126.23.1368.1368

Published: 2015

Journal Articles

ASXL1 and ASXL2 Mutations in Childhood AML Are Strongly Associated with t(8;21) but Do Not Independently Impact on Prognosis: A Report from the Children's Oncology Group and NCI/COG Target Initiative

Jason E. Farrar, MD, Todd A. Alonzo, PhD, Rhonda E. Ries, MA, Robert B. Gerbing, MA, Jaime M. Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, Marco A Marra, PhD, Andrew J. Mungall, PhD, Karen Mungall, PhD, Yussanne Ma, PhD, William Long, PhD, Stuart Zong, E. Anders Kolb, MD, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD

Blood (2015) 126 (23): 2587.

https://doi.org/10.1182/blood.V126.23.2587.2587

Published: 2015

Journal Articles

Comprehensive Genomic and Transcript Profiling of CBL Gene in Childhood AML: A Report from Children's Oncology Group Studies AAML03P1, AAML0531 and COG/NCI Target AML Initiative

Blood (2015) 126 (23): 170.

https://doi.org/10.1182/blood.V126.23.170.170

Published: 2015

Journal Articles

Rearrangements in Nucleoporin Family of Genes in Childhood Acute Myeloid Leukemia: A Report from Children Oncology Group and NCI/COG Target AML Initiative

Blood (2015) 126 (23): 169.

https://doi.org/10.1182/blood.V126.23.169.169

Published: 2015

Journal Articles

CSF3R Mutations Represent a Novel Therapeutic Target in Pediatric AML with a High Degree of Overlap with CEBPA Mutations: a Report from COG AAML0531 and COG/NCI Target AML Initiative

Blood (2015) 126 (23): 174.

https://doi.org/10.1182/blood.V126.23.174.174

Published: 2015

Journal Articles

Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative

Blood (2015) 126 (23): 87.

https://doi.org/10.1182/blood.V126.23.87.87

Published: 2015

Journal Articles

PIM3-SCO2 Fusion Is a Novel Transcription-Induced Chimera That Is Highly Prevalent In Childhood AML

Julia Kuhn, BA, Daoud Meerzaman, MD, Rhonda E. Ries, MA, Filippo Milano, MD, PhD, Alan S. Gamis, MD, MPH, Todd A. Alonzo, PhD, Jaime Guidry-Auvil, Ph.D., Tanja M. Davidsen, PhD, Malcolm A. Smith, MD, PhD, Yan Chunhua, Chih Hao Hsu, Cu Nguyen, Daniela S. Gerhard, Ph.D., Daniel Wai, Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD

Blood (2013) 122 (21): 2549.

https://doi.org/10.1182/blood.V122.21.2549.2549

Published: 2013

Journal Articles

Genome-Wide DNA Methylation Analysis Reveals Biological and Clinical Insights In Relapsed Childhood Acute Lymphoblastic Leukemia: A Report From The COG ALL Target Project

Huimin Geng, PhD, Mignon L. Loh, MD, Richard C. Harvey, PhD, I-Ming Chen, DVM, Meenakshi Devidas, PhD, Tanja M. Davidsen, PhD, Jaime M. Guidry Auvil, PhD, Daniela S. Gerhard, Ph.D., Malcolm A. Smith, MD PhD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Julie M. Gastier-Foster, PhD, Cheryl L. Willman, MD, Charles G. Mullighan, MBBS MSc MD, Stephen P. Hunger, MD, Ari Melnick, MD

Blood (2013) 122 (21): 3736.

https://doi.org/10.1182/blood.V122.21.3736.3736

Published: 2013

Journal Articles

Clinically Significant Mutations, Deletions and Translocations Involving ETV6 Identified by Whole Genome and Whole Exome Sequencing; Report From NCI/COG Target AML Initiative

Heather L. Helton, MD, Rhonda E. Ries, MA, Todd A. Alonzo, PhD, Robert B. Gerbing, M.A., Lisa R. Trevino, PhD, Jason Farrar, M.D., Jaime M. Guidry Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Donna M. Muzny, Alan S. Gamis, MD, MPH, Janet Franklin, MD, MPH, David A. Wheeler, PhD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD

Blood (2012) 120 (21): 125.

https://doi.org/10.1182/blood.V120.21.125.125

Published: 2012

Journal Articles

Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study

Soheil Meshinchi, MD, PhD, Rhonda E. Ries, MA, Lisa R. Trevino, PhD, Oliver A. Hampton, PhD, Todd Alonzo, PhD, Jason E. Farrar, MD, Jaime M. Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, PhD, Donna M. Muzny, Alan S. Gamis, MD, MPH, Heather L. Helton, MD, David A. Wheeler, PhD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD

Blood (2012) 120 (21): 123.

https://doi.org/10.1182/blood.V120.21.123.123

Published: 2012

Journal Articles

Genome Wide Promoter Methylation Patterns Predict AML Subtype Outcomes and Identify Novel Pathways Characterizing Diagnostic and Relapsed Disease in Children

Michael Ochs, Ph.D., Jason Farrar, M.D., Michael Considine, M.S., Rhonda E. Ries, MA, Lisa R. Trevino, PhD, Todd A. Alonzo, PhD, Jaime Guidry-Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Donna M. Muzny, Alan S. Gamis, MD, MPH, David A. Wheeler, PhD, Heather L. Helton, MD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Soheil Meshinchi, MD, PhD, Robert J. Arceci, MD, PhD

Blood (2012) 120 (21): 1287.

https://doi.org/10.1182/blood.V120.21.1287.1287

Published: 2012

Journal Articles

Integrative Network Analysis of Pediatric AML Whole Genomes, cDNA Expression and Clinical Data Elements Reveals Shared As Well As t(8;21), Inv16 and MLL Specific Pathways; A Report From COG/NCI Target AML Initiative

Hamid Bolouri, PhD, Rhonda E. Ries, MA, Ranjani Ramamurthy, MS, Todd A. Alonzo, PhD, Jaime M. Guidry Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Alan S. Gamis, MD, MPH, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD

Blood (2012) 120 (21): 3519.

https://doi.org/10.1182/blood.V120.21.3519.3519

Published: 2012

NARROW

Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma

Burkitt Lymphoma Genome Sequencing Project (BLGSP): Integrative Genomic and Transcriptomic Characterization of Burkitt Lymphoma

Discovery and Validation of Cell-Surface Protein Mesothelin (MSLN) As a Novel Therapeutic Target in AML: Results from the COG/NCI Target AML Initiative

Burkitt Lymphoma Genome Sequencing Project (BLGSP): Introduction

Marked Differences in the Genomic Landscape of Pediatric Compared to Adult Acute Myeloid Leukemia: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia

CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML

TET2 Mutations Are Highly Associated with RUNX1-RUNX1T1 Translocations and NPMc+ in Childhood AML: a Report from Children's Oncology Group AAML03P1, AAML0531 and NCI/COG Target AML Initiative

ASXL1 and ASXL2 Mutations in Childhood AML Are Strongly Associated with t(8;21) but Do Not Independently Impact on Prognosis: A Report from the Children's Oncology Group and NCI/COG Target Initiative

Comprehensive Genomic and Transcript Profiling of CBL Gene in Childhood AML: A Report from Children's Oncology Group Studies AAML03P1, AAML0531 and COG/NCI Target AML Initiative

Rearrangements in Nucleoporin Family of Genes in Childhood Acute Myeloid Leukemia: A Report from Children Oncology Group and NCI/COG Target AML Initiative

CSF3R Mutations Represent a Novel Therapeutic Target in Pediatric AML with a High Degree of Overlap with CEBPA Mutations: a Report from COG AAML0531 and COG/NCI Target AML Initiative

Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative

PIM3-SCO2 Fusion Is a Novel Transcription-Induced Chimera That Is Highly Prevalent In Childhood AML

Genome-Wide DNA Methylation Analysis Reveals Biological and Clinical Insights In Relapsed Childhood Acute Lymphoblastic Leukemia: A Report From The COG ALL Target Project

Clinically Significant Mutations, Deletions and Translocations Involving ETV6 Identified by Whole Genome and Whole Exome Sequencing; Report From NCI/COG Target AML Initiative

Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study

Genome Wide Promoter Methylation Patterns Predict AML Subtype Outcomes and Identify Novel Pathways Characterizing Diagnostic and Relapsed Disease in Children

Integrative Network Analysis of Pediatric AML Whole Genomes, cDNA Expression and Clinical Data Elements Reveals Shared As Well As t(8;21), Inv16 and MLL Specific Pathways; A Report From COG/NCI Target AML Initiative

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American Society of Hematology

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American Society of Hematology

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