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Timothy W McKeithan
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Journal Articles

Single-Cell Transcriptomics of Human TET2 Knockout CD4 T-Cells and Their Clonal Evolution

Yuping Li, PhD, Xiaoqian Liu, MD PhD, Xuxiang Liu, PhD, Xiwei Wu, PhD, Alyssa Bouska, PhD, Waseem G. Lone, PhD, Chan-Wang J. Lio, PhD, Tyler Herek, BS,MS, Logan Lee, BS, Gehong Dong, MD PhD, Jinhui Wang, PhD, Chih-Hong Lou, PhD, Wei Qi, MD, Kunal Shetty, BS, Timothy W. McKeithan, MD PhD, Javeed Iqbal, PhD, Wing (John) C. Chan, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-143113
Published: 2020
Journal Articles

Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma

Tayla B. Heavican, Alyssa Bouska, Jiayu Yu, Waseem Lone, Catalina Amador, Qiang Gong, Weiwei Zhang, Yuping Li, Bhavana J. Dave, Maarja-Liisa Nairismägi, Timothy C. Greiner, Julie Vose, Dennis D. Weisenburger, Cynthia Lachel, Chao Wang, Kai Fu, Jadd M. Stevens, Soon Thye Lim, Choon Kiat Ong, Randy D. Gascoyne, Edoardo Missiaglia, Francois Lemonnier, Corinne Haioun, Sylvia Hartmann, Martin Bjerregård Pedersen, Maria Antonella Laginestra, Ryan A. Wilcox, Bin Tean Teh, Noriaki Yoshida, Koichi Ohshima, Masao Seto, Andreas Rosenwald, German Ott, Elias Campo, Lisa M. Rimsza, Elaine S. Jaffe, Rita M. Braziel, Francesco d’Amore, Giorgio Inghirami, Francesco Bertoni, Laurence de Leval, Philippe Gaulard, Louis M. Staudt, Timothy W. McKeithan, Stefano Pileri, Wing C. Chan, Javeed Iqbal
Journal: Blood
Blood (2019) 133 (15): 1664–1676.
https://doi.org/10.1182/blood-2018-09-872549
Published: 2019
Includes: Supplemental data
Journal Articles

Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets

CME
Alyssa Bouska, Chengfeng Bi, Waseem Lone, Weiwei Zhang, Ambreen Kedwaii, Tayla Heavican, Cynthia M. Lachel, Jiayu Yu, Roberto Ferro, Nanees Eldorghamy, Timothy C. Greiner, Julie Vose, Dennis D. Weisenburger, Randy D. Gascoyne, Andreas Rosenwald, German Ott, Elias Campo, Lisa M. Rimsza, Elaine S. Jaffe, Rita M. Braziel, Reiner Siebert, Rodney R. Miles, Sandeep Dave, Anupama Reddy, Jan Delabie, Louis M. Staudt, Joo Y. Song, Timothy W. McKeithan, Kai Fu, Michael Green, Wing C. Chan, Javeed Iqbal
Journal: Blood
Blood (2017) 130 (16): 1819–1831.
https://doi.org/10.1182/blood-2017-02-767335
Published: 2017
Includes: Supplemental data
Journal Articles

Driver Mutations Affecting Natural Killer/T Cell Lymphoma

Gehong DONG, PhD, Qiang Gong, PhD, Jinhui Wang, Xiwei Wu, PhD, Yuping Li, PhD, Leticia Quintanilla-Martinez Fend, Prof. Dr., Jingwen Wang, MD, Hong-gang Liu, Timothy W. McKeithan, MD PhD, Wing Chung Chan, MD
Journal: Blood
Blood (2016) 128 (22): 4109.
https://doi.org/10.1182/blood.V128.22.4109.4109
Published: 2016
Journal Articles

Generation of Natural Killer Cell Lymphoma Models In Vitro by Gene Editing

Gehong Dong, PhD, Yuping Li, PhD, Bei Jiang, Jiing-Kuan Yee, Dean A. Lee, MD PhD, Timothy W. McKeithan, MD PhD, Wing Chung Chan, MD
Journal: Blood
Blood (2016) 128 (22): 2724.
https://doi.org/10.1182/blood.V128.22.2724.2724
Published: 2016
Journal Articles

Comprehensive Genomic Analysis of Adult Burkitt Lymphoma Identifies the B-Cell Receptor Signaling Pathway As a Potential Therapeutic Target

Alyssa Bouska, PhD, Chengfeng Bi, MD PhD, Waseem Lone, PhD, Weiwei Zhang, PhD, Ambreen Kedwaii, MS, Tayla B Heavican, BS, Cynthia M Lachel, BS, Jiayu Yu, MD MS, Kai Fu, MD PhD, Roberto A. Ferro, MD, Nanees Eldorghamy, MD, Timothy C. Greiner, MD, Julie M Vose, MD, Dennis D Weisenburger, MD, Randy D Gascoyne, MD, Andreas Rosenwald, MD, German Ott, Elias Campo, MD PhD, Lisa M Rimsza, MD, Elaine S. Jaffe, MD, Rita M Braziel, MD, Reiner Siebert, Rodney R. Miles, MD PhD, Sandeep Dave, MD, Anupama Reddy, Timothy W. McKeithan, MD PhD, Louis M. Staudt, MD PhD, Michael R Green, PhD, Wing Chung Chan, MD, Javeed Iqbal, MS, PhD
Journal: Blood
Blood (2016) 128 (22): 4095.
https://doi.org/10.1182/blood.V128.22.4095.4095
Published: 2016
Journal Articles

Molecular Subgroups of Peripheral T-Cell Lymphoma Evolve By Distinct Genetic Pathways

Tayla B Heavican, BS, Jiayu Yu, MD MS, Alyssa Bouska, PhD, Timothy C Greiner, MS, MD, Cynthia M Lachel, BS, Chao Wang, MD, Bhavana J Dave, Catalina C Amador, MD, Kai Fu, MD PhD, Julie M Vose, MD, Dennis D Weisenburger, MD, Randy D Gascoyne, MD, Sylvia Hartmann, MD, Martin Bjerregård Pedersen, Ryan Wilcox, MD PhD, Bin Tean Teh, MD PhD, Soon Thye Lim, MD, Choon Kiat Ong, Masao Seto, MD PhD, Francoise Berger, Andreas Rosenwald, MD, German Ott, Elias Campo, Lisa M Rimsza, MD, Elaine S. Jaffe, MD, Rita M Braziel, MD, Francesco A d'Amore, MD, Giorgio Inghirami, MD, Francesco Bertoni, MD, Louis Staudt, MD PhD, Timothy W. McKeithan, MD PhD, Stefano A Pileri, Wing Chung Chan, MD, Javeed Iqbal, PhD
Journal: Blood
Blood (2016) 128 (22): 4096.
https://doi.org/10.1182/blood.V128.22.4096.4096
Published: 2016
Journal Articles

Microrna-17~92 Cluster Upregulates NF-KB Activity Via Suppressing Multiple NF-KB Negative Regulators Mediating Ubiquitination

Xianhuo Wang, MD, Huaqing Wang, Chengfeng Bi, Xiaoyan Zhang, Xin Huang, Xuan Zhang, Javeed Iqbal, George W Wright, Louis M Staudt, Wing C Chan, Timothy W McKeithan, Ping Wang, Huilai Zhang, Kai Fu, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3638.
https://doi.org/10.1182/blood.V126.23.3638.3638
Published: 2015
Journal Articles

IDH2 R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma

Chao Wang, Timothy W. McKeithan, Qiang Gong, Weiwei Zhang, Alyssa Bouska, Andreas Rosenwald, Randy D. Gascoyne, Xiwei Wu, Jinhui Wang, Zahid Muhammad, Bei Jiang, Joseph Rohr, Andrew Cannon, Christian Steidl, Kai Fu, Yuping Li, Stacy Hung, Dennis D. Weisenburger, Timothy C. Greiner, Lynette Smith, German Ott, Eleanor G. Rogan, Louis M. Staudt, Julie Vose, Javeed Iqbal, Wing C. Chan
Journal: Blood
Blood (2015) 126 (15): 1741–1752.
https://doi.org/10.1182/blood-2015-05-644591
Published: 2015
Includes: Supplemental data
Journal Articles

Global microRNA expression profiling uncovers molecular markers for classification and prognosis in aggressive B-cell lymphoma

Javeed Iqbal, Yulei Shen, Xin Huang, Yanyan Liu, Laura Wake, Cuiling Liu, Karen Deffenbacher, Cynthia M. Lachel, Chao Wang, Joseph Rohr, Shuangping Guo, Lynette M. Smith, George Wright, Sharathkumar Bhagavathi, Karen Dybkaer, Kai Fu, Timothy C. Greiner, Julie M. Vose, Elaine Jaffe, Lisa Rimsza, Andreas Rosenwald, German Ott, Jan Delabie, Elias Campo, Rita M. Braziel, James R. Cook, Raymond R. Tubbs, James O. Armitage, Dennis D. Weisenburger, Louis M. Staudt, Randy D. Gascoyne, Timothy W. McKeithan, Wing C. Chan
Journal: Blood
Blood (2015) 125 (7): 1137–1145.
https://doi.org/10.1182/blood-2014-04-566778
Published: 2015
Includes: Supplemental data
Journal Articles

Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma

Alyssa Bouska, Timothy W. McKeithan, Karen E. Deffenbacher, Cynthia Lachel, George W. Wright, Javeed Iqbal, Lynette M. Smith, Weiwei Zhang, Can Kucuk, Andrea Rinaldi, Francesco Bertoni, Jude Fitzgibbon, Kai Fu, Dennis D. Weisenburger, Timothy C. Greiner, Bhavana J. Dave, Randy D. Gascoyne, Andreas Rosenwald, German Ott, Elias Campo, Lisa M. Rimsza, Jan Delabie, Elaine S. Jaffe, Rita M. Braziel, Joseph M. Connors, Louis M. Staudt, Wing-Chung Chan
Journal: Blood
Blood (2014) 123 (11): 1681–1690.
https://doi.org/10.1182/blood-2013-05-500595
Published: 2014
Includes: Supplemental data
Journal Articles

microRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma

Cuiling Liu, Javeed Iqbal, Julie Teruya-Feldstein, Yulei Shen, Magdalena Julia Dabrowska, Karen Dybkaer, Megan S. Lim, Roberto Piva, Antonella Barreca, Elisa Pellegrino, Elisa Spaccarotella, Cynthia M. Lachel, Can Kucuk, Chun-Sun Jiang, Xiaozhou Hu, Sharathkumar Bhagavathi, Timothy C. Greiner, Dennis D. Weisenburger, Patricia Aoun, Sherrie L. Perkins, Timothy W. McKeithan, Giorgio Inghirami, Wing C. Chan
Journal: Blood
Blood (2013) 122 (12): 2083–2092.
https://doi.org/10.1182/blood-2012-08-447375
Published: 2013
Includes: Supplemental data
Journal Articles

Genome-wide miRNA profiling of mantle cell lymphoma reveals a distinct subgroup with poor prognosis

Javeed Iqbal, Yulei Shen, Yanyan Liu, Kai Fu, Elaine S. Jaffe, Cuiling Liu, Zhongfeng Liu, Cynthia M. Lachel, Karen Deffenbacher, Timothy C. Greiner, Julie M. Vose, Sharathkumar Bhagavathi, Louis M. Staudt, Lisa Rimsza, Andreas Rosenwald, German Ott, Jan Delabie, Elias Campo, Rita M. Braziel, James R. Cook, Raymond R. Tubbs, Randy D. Gascoyne, James O. Armitage, Dennis D. Weisenburger, Timothy W. McKeithan, Wing C. Chan
Journal: Blood
Blood (2012) 119 (21): 4939–4948.
https://doi.org/10.1182/blood-2011-07-370122
Published: 2012
Includes: Supplemental data