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Journal Articles

Bitter Taste Receptors System Is Expressed and Functional in Both HSCs and Leukemic Cells

Valentina Salvestrini, PhD, Valentina Pensato, Marilena Ciciarello, PhD, Giorgia Simonetti, PhD, Dorian Forte, Simon Mendez-Ferrer, PhD, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti

Blood (2018) 132 (Supplement 1): 2560.

https://doi.org/10.1182/blood-2018-99-111806

Published: 2018

Journal Articles

Bitter Taste Receptors Are Expressed on Acute Myeloid Leukemia Cells and Their Activation Results in Quiescence Induction and Prevention of Migration

Valentina Salvestrini, PhD, Marilena Ciciarello, Giorgia Simonetti, PhD, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti, MD PhD

Blood (2017) 130 (Supplement 1): 3949.

https://doi.org/10.1182/blood.V130.Suppl_1.3949.3949

Published: 2017

Journal Articles

The Induction of Inhibitory Pathways in Dendritic Cells May Hamper the Efficient Activation of Anti-Leukemia T Cells within Chemotherapy-Induced Immunogenic Cell Death

Darina Ocadlikova, PhD, Mariangela Lecciso, M.S., Elisa Orioli, M.S., Elena De Marchi, M.S., Sabina Sangaletti, PhD, Sara Trabanelli, PhD, Camilla Jandus, PhD, Valentina Salvestrini, PhD, Pedro Romero, professor, Mario Paolo Colombo, M.S., Francesco Di Virgilio, Roberto M Lemoli, Professor, Michele Cavo, Elena Adinolfi, Antonio Curti, MD PhD

Blood (2015) 126 (23): 1019.

https://doi.org/10.1182/blood.V126.23.1019.1019

Published: 2015

Journal Articles

The Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) Regulates the Function and Migration of Leukemic Blasts through CD63/PI3K/AKT/P21 Axis

Dorian Forte, PhD Student, Valentina Salvestrini, PhD, Lucia Catani, PhD, Roberto M Lemoli, Professor, Michele Cavo, Antonio Curti, MD PhD

Blood (2015) 126 (23): 2394.

https://doi.org/10.1182/blood.V126.23.2394.2394

Published: 2015

Journal Articles

P2X7 Receptor Activation By ATP As Target of Novel Therapies in Acute Myeloid Leukemia

Valentina Salvestrini, Stefania Orecchioni, Francesca Reggiani, Giovanna Talarico, Elisa Orioli, Elena Adinolfi, Francesco Bertolini, Francesco Di Virgilio, Michele Cavo, Roberto Massimo Lemoli, MD, Antonio Curti, MD PhD

Blood (2015) 126 (23): 3684.

https://doi.org/10.1182/blood.V126.23.3684.3684

Published: 2015

Journal Articles

Proteomic Profile Of CD34+ Cells From Chronic Myeloid Leukemia Patients and From Normal Donors

Maria Rosaria Ricciardi, Valentina Salvestrini, Mattia Forcato, Roberto Licchetta, Simone Mirabilii, Lara Rossi, Matteo Allegretti, Martina Vincenzi, Simona Salati, Phd, Fausto Castagnetti, Gianantonio Rosti, Giuliana Alimena, Rossella Manfredini, PhD, Silvio Bicciato, PhD, Roberto Lemoli, Agostino Tafuri

Blood (2013) 122 (21): 2712.

https://doi.org/10.1182/blood.V122.21.2712.2712

Published: 2013

Journal Articles

Proteomic Signature of CD34+ Cells From Chronic Myeloid Leukemia Patients

Maria Rosaria Ricciardi, Valentina Salvestrini, Roberto Licchetta, Simone Mirabilii, Maria Teresa Petrucci, Lara Rossi, Matteo Allegretti, Simona Salati, Fausto Castagnetti, Gianantonio Rosti, prof, Giuliana Alimena, Rossella Manfredini, Roberto M. Lemoli, Agostino Tafuri

Blood (2012) 120 (21): 3733.

https://doi.org/10.1182/blood.V120.21.3733.3733

Published: 2012

Journal Articles

Human Blood Dendritic Cells Induce Tregs Through the PGE2-Independent Expression of an Active Form of IDO2 Enzyme

Sara Trabanelli, Darina Ocadlikova, Marilena Ciciarello, Valentina Salvestrini, Cecilia Evangelisti, Richard Metz, Lisa Laury-Kleintop, George Prendergast, Antonio Curti, MD, Roberto M. Lemoli

Blood (2012) 120 (21): 1047.

https://doi.org/10.1182/blood.V120.21.1047.1047

Published: 2012

Journal Articles

The sixth sense: hematopoietic stem cells detect danger through purinergic signaling

Lara Rossi, Valentina Salvestrini, Davide Ferrari, Francesco Di Virgilio, Roberto M. Lemoli

Blood (2012) 120 (12): 2365–2375.

https://doi.org/10.1182/blood-2012-04-422378

Published: 2012

Journal Articles

Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice

Valentina Salvestrini, Roberta Zini, Lara Rossi, Sara Gulinelli, Rossella Manfredini, Elisa Bianchi, Wanda Piacibello, Luisa Caione, Giorgia Migliardi, Maria Rosaria Ricciardi, Agostino Tafuri, Marco Romano, Simona Salati, Francesco Di Virgilio, Sergio Ferrari, Michele Baccarani, Davide Ferrari, Roberto M. Lemoli

Blood (2012) 119 (1): 217–226.

https://doi.org/10.1182/blood-2011-07-370775

Published: 2012

Includes: Supplemental data

Journal Articles

PGE 2 -Independent Expression of Indoleamine 2,3-Dioxygenase-2 (IDO2) Supports the Tolerogenic Function of Monocyte-Derived Dendritic Cells,

Sara Trabanelli, Antonio Curti, MD, Darina Ocadlikova, Cecilia Evangelisti, Valentina Salvestrini, Marilena Ciciarello, Michela Aluigi, PhD, Lara Rossi, Richard Metz, Lisa Laury-Kleintop, George Prendergast, Roberto M. Lemoli, MD

Blood (2011) 118 (21): 3231.

https://doi.org/10.1182/blood.V118.21.3231.3231

Published: 2011

Journal Articles

Human Monocyte-Derived Dendritic Cells Are Tolerogenic through Both IDO1 and IDO2

Sara Trabanelli, PhD, Antonio Curti, PhD, Darina Očadlíková, PhD, Cecilia Evangelisti, PhD, Valentina Salvestrini, PhD, Richard Metz, PhD, Lisa Laury-Kleintop, PhD, George Prendergast, Roberto M. Lemoli, MD

Blood (2010) 116 (21): 4298.

https://doi.org/10.1182/blood.V116.21.4298.4298

Published: 2010

Journal Articles

Purinergic Stimulation of Human Bone Marrow-Derived Mesenchymal Stem Cells Modulate Their Function and Differentiation Potential.

Marilena Ciciarello, Valentina Salvestrini, Davide Ferrari, Sara Gulinelli, Roberta Zini, Rossella Manfredini, Luisa Caione, Wanda Piacibello, MD, Giovanna Lucchetti, Lara Rossi, Sergio Ferrari, Francesco Di Virgilio, Roberto M. Lemoli, MD

Blood (2010) 116 (21): 3848.

https://doi.org/10.1182/blood.V116.21.3848.3848

Published: 2010

Journal Articles

Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34 − cell population with intrinsic resistance to imatinib

Roberto M. Lemoli, Valentina Salvestrini, Elisa Bianchi, Francesco Bertolini, Miriam Fogli, Marilina Amabile, Agostino Tafuri, Simona Salati, Roberta Zini, Nicoletta Testoni, Cristina Rabascio, Lara Rossi, Ines Martin-Padura, Fausto Castagnetti, Paola Marighetti, Giovanni Martinelli, Michele Baccarani, Sergio Ferrari, Rossella Manfredini

Blood (2009) 114 (25): 5191–5200.

https://doi.org/10.1182/blood-2008-08-176016

Published: 2009

Includes: Supplemental data

Journal Articles

Purinergic Signaling Differentially Modulates Normal and Leukemic Hematopoiesis.

Valentina Salvestrini, BS, Sara Gulinelli, BS, Roberta Zini, BS, Luisa Caione, BS, Giorgia Migliardi, BS, Wanda Piacibello, MD, Davide Ferrari, PhD, Francesco Di Virgilio, MD, Sergio Ferrari, MD, Rossella Manfredini, PhD, Roberto M Lemoli, MD

Blood (2009) 114 (22): 1436.

https://doi.org/10.1182/blood.V114.22.1436.1436

Published: 2009

Journal Articles

Purinergic Signaling Modulates Human Bone Marrow-Derived Mesenchymal Stem Cells Function.

Valentina Salvestrini, BS, Davide Ferrari, PhD, Sara Gulinelli, BS, Luisa Caione, BS, Wanda Piacibello, MD, Roberta Zini, BS, Marilena Ciciarello, PhD, Rossella Manfredini, PhD, Giovanna Lucchetti, BS, Sergio Ferrari, MD, Francesco Di Virgilio, MD, Roberto M Lemoli, MD

Blood (2009) 114 (22): 1441.

https://doi.org/10.1182/blood.V114.22.1441.1441

Published: 2009

Journal Articles

The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology

Antonio Curti, Sara Trabanelli, Valentina Salvestrini, Michele Baccarani, Roberto M. Lemoli

Blood (2009) 113 (11): 2394–2401.

https://doi.org/10.1182/blood-2008-07-144485

Published: 2009

Journal Articles

Molecular and Functional Analysis of Stem Cell Compartment of Chronic Myelogenous Leukemia Reveals the Presence of a CD34 − cell Population with Intrinsic Resistance to IMATINIB Treatment

Valentina Salvestrini, Rossella Manfredini, MD, Miriam Fogli, Elisa Bianchi, Simona Salati, PhD, Marilina Amabile, Francesco Bertolini, Agostino Tafuri, Roberta Zini, Nicoletta Testoni, Cristina Rabascio, Lara Rossi, Giovanni Martinelli, Michele Baccarani, MD, Sergio Ferrari, Roberto M Lemoli

Blood (2008) 112 (11): 4221.

https://doi.org/10.1182/blood.V112.11.4221.4221

Published: 2008

Journal Articles

Quantitative Molecular Expression of the Immunoregulatory Enzyme Indoleamine 2,3-Dioxygenase in Acute Myeloid Leukemia Cells as a Possible Marker for Minimal Residual Disease Detection.

Michela Aluigi, PhD, Antonio Curti, MD, Emanuela Ottaviani, PhD, Giovanna Lucchetti, BS, Valentina Salvestrini, BS, Alessandra D’Addio, MD, Sara Trabanelli, BS, Francesca Fiore, MD, Massimo Massaia, MD, Giovanni Martinelli, MD, Michele Baccarani, MD, Roberto M. Lemoli, MD

Blood (2007) 110 (11): 4229.

https://doi.org/10.1182/blood.V110.11.4229.4229

Published: 2007

Journal Articles

Modulation of Tryptophan Catabolism by Acute Myeloid Leukemia Cells Acts as a General Mechanism of Immune Tolerance Via the Induction of T Regulatory Cells.

Antonio Curti, MD, Valentina Salvestrini, BS, Michela Aluigi, PhD, Sara Trabanelli, BS, Emanuela Ottaviani, BS, Ilaria Durelli, BS, Alberto L. Horenstein, MD, Francesca Fiore, MD, Massimo Massaia, MD, Milena Piccioli, BS, Stefano Pileri, MD, Giovanni Martinelli, MD, Michele Baccarani, MD, Roberto M. Lemoli, MD

Blood (2007) 110 (11): 1345.

https://doi.org/10.1182/blood.V110.11.1345.1345

Published: 2007

NARROW

Bitter Taste Receptors System Is Expressed and Functional in Both HSCs and Leukemic Cells

Bitter Taste Receptors Are Expressed on Acute Myeloid Leukemia Cells and Their Activation Results in Quiescence Induction and Prevention of Migration

The Induction of Inhibitory Pathways in Dendritic Cells May Hamper the Efficient Activation of Anti-Leukemia T Cells within Chemotherapy-Induced Immunogenic Cell Death

The Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) Regulates the Function and Migration of Leukemic Blasts through CD63/PI3K/AKT/P21 Axis

P2X7 Receptor Activation By ATP As Target of Novel Therapies in Acute Myeloid Leukemia

Proteomic Profile Of CD34+ Cells From Chronic Myeloid Leukemia Patients and From Normal Donors

Proteomic Signature of CD34+ Cells From Chronic Myeloid Leukemia Patients

Human Blood Dendritic Cells Induce Tregs Through the PGE2-Independent Expression of an Active Form of IDO2 Enzyme

The sixth sense: hematopoietic stem cells detect danger through purinergic signaling

Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice

PGE 2 -Independent Expression of Indoleamine 2,3-Dioxygenase-2 (IDO2) Supports the Tolerogenic Function of Monocyte-Derived Dendritic Cells,

Human Monocyte-Derived Dendritic Cells Are Tolerogenic through Both IDO1 and IDO2

Purinergic Stimulation of Human Bone Marrow-Derived Mesenchymal Stem Cells Modulate Their Function and Differentiation Potential.

Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34 − cell population with intrinsic resistance to imatinib

Purinergic Signaling Differentially Modulates Normal and Leukemic Hematopoiesis.

Purinergic Signaling Modulates Human Bone Marrow-Derived Mesenchymal Stem Cells Function.

The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology

Molecular and Functional Analysis of Stem Cell Compartment of Chronic Myelogenous Leukemia Reveals the Presence of a CD34 − cell Population with Intrinsic Resistance to IMATINIB Treatment

Quantitative Molecular Expression of the Immunoregulatory Enzyme Indoleamine 2,3-Dioxygenase in Acute Myeloid Leukemia Cells as a Possible Marker for Minimal Residual Disease Detection.

Modulation of Tryptophan Catabolism by Acute Myeloid Leukemia Cells Acts as a General Mechanism of Immune Tolerance Via the Induction of T Regulatory Cells.

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American Society of Hematology

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American Society of Hematology

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