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Journal Articles

CD19/CD22 targeting with cotransduced CAR T cells to prevent antigen-negative relapse after CAR T-cell therapy for B-cell ALL

Clinical Trials & Observations Brief Report
Sara Ghorashian, Giovanna Lucchini, Rachel Richardson, Kyvi Nguyen, Craig Terris, Aleks Guvenel, Macarena Oporto-Espuelas, Jenny Yeung, Danielle Pinner, Jan Chu, Lindsey Williams, Ka-Yuk Ko, Chloe Walding, Kelly Watts, Sarah Inglott, Rebecca Thomas, Christopher Connor, Stuart Adams, Emma Gravett, Kimberly Gilmour, Alka Lal, Sangeetha Kunaseelan, Bilyana Popova, Andre Lopes, Yenting Ngai, Allan Hackshaw, Evangelia Kokalaki, Milena Balasch Carulla, Khushnuma Mullanfiroze, Arina Lazareva, Vesna Pavasovic, Anupama Rao, Jack Bartram, Ajay Vora, Robert Chiesa, Juliana Silva, Kanchan Rao, Denise Bonney, Robert Wynn, Martin Pule, Rachael Hough, Persis J. Amrolia
Journal: Blood
Blood (2024) 143 (2): 118–123.
https://doi.org/10.1182/blood.2023020621
Published: 2024
Includes: Supplemental data
Journal Articles

A Single Centre Cohort Study of Monitoring B Cell Populations in the Bone Marrow and Peripheral Blood Post Tisagenlecleucel Therapy of Relapsed/Refractory Acute Lymphoblastic Leukaemia

Sneha Fernandes, Archana Rauthan, Macarena Oporto Epuelas, Katherine Berry, Saskia Burridge, Charlotte Twigdon-Williams, Christopher Connor, Mark Davis, Kimberly Gilmour, Rebecca Thomas, Phil Ancliff, Jack Bartram, Robert Chiesa, Giovanna Lucchini, Vesna Pavasovic, Anupama Rao, Kanchan Rao, Sujith Samarasinghe, Juliana Silva, Ajay Vora, Persis Amrolia, Sara Ghorashian
Journal: Blood
Blood (2023) 142 (Supplement 1): 3508.
https://doi.org/10.1182/blood-2023-182730
Published: 2023
Journal Articles

Routine Whole Genome Sequencing for All Children with Hematological Malignancies Defines a New Standard of Care - Data of the First 152 Cases from the NHS England Genomic Medicine Service

Angus Hodder, Sarah Leiter, Aditi Vedi, Phillipa May, Dilys Addy, Phil Ancliff, Julian Cano-Flanagan, Jane Chalker, Danny Cheng, Yasmin Clinch, Caryl Dryden, Sara Ghorashian, David O'Connor, Vesna Pavasovic, Anupama Rao, Sujith Samarasinghe, Iryna Stasevich, Ajay Vora, Michael Hubank, Dame Lyn Chitty, Sam Behjati, Jack Bartram
Journal: Blood
Blood (2023) 142 (Supplement 1): 3656.
https://doi.org/10.1182/blood-2023-186025
Published: 2023
Journal Articles

Dual Antigen Targeting with Co-Transduced CD19/22 CAR T Cells May Prevent Antigen-Negative Relapse after CAR T Cell Therapy for Relapsed/Refractory ALL

Sara Ghorashian, Giovanna Lucchini, Rachel Richardson, Kyvi Nguyen, Craig Terris, Macarena Oporto-Espuelas, Jenny Yeung, Danielle Pinner, Jan Chu, Lindsey Williams, Ka-yuk Ko, Chloe Walding, Kelly Watts, Sarah Inglott, Stuart Adams, Emma Gravett, Kimberly Gilmour, Alka Lal, Sangeetha Kunaseelan, Bilyana Popova, Andre Lopes, Yenting Ngai, Evangelia K Kokalaki, Milena Balasch Carulla, Khushnuma Mullanfiroze, Arina Lazareva, Vesna Pavasovic, Anupama Rao, Jack Bartram, Ajay Vora, Robert Chiesa, Juliana Silva, Kanchan Rao, Katherine Clesham, Denise Bonney, Robert F Wynn, Martin Pule, Rachael E Hough, Persis J Amrolia
Journal: Blood
Blood (2022) 140 (Supplement 1): 10352–10354.
https://doi.org/10.1182/blood-2022-164879
Published: 2022
Journal Articles

Outcomes of Children and Young Adults with Acute Lymphoblastic Leukaemia Administered Inotuzumab Pre CAR-T Therapy

Khushnuma Mullanfiroze, Giorgio Ottaviano, Avijeet K Mishra, Maria Gabelli, Arina Lazareva, Saskia Burridge, Susan Farish, Jan Chu, Kirsty Sharplin, David I. Marks, Maeve A O'Reilly, Emma Nicholson, Kelly Watts, Denise Bonney, Danny Cheng, Jack Bartram, Sujith Samarasinghe, Vesna Pavasovic, Anupama Rao, Philip Ancliffe, Ajay Vora, Giovanna Lucchini, Robert Chiesa, Paul Veys, Kanchan Rao, Persis J Amrolia, Sara Ghorashian
Journal: Blood
Blood (2021) 138 (Supplement 1): 1743.
https://doi.org/10.1182/blood-2021-148820
Published: 2021
Journal Articles

ALL Maintenance Treatment for Early Loss of B-Cell Aplasia after Tisagenlecleucel Therapy

Maria Gabelli, Macarena Oporto Espuelas, Denise Bonney, Saskia Burridge, Susan Farish, Khushnuma Mullanfiroze, Arina Lazareva, Sujith Samarasinghe, Philip Ancliffe, Ajay Vora, Jack Bartram, Emma Hedges, Kirsty Ware, Lindsey Young, Chiara Cugno, Lenka Chenchara, Juliana Silva, Oana Mirci-Danicar, Lynne Riley, Vesna Pavasovic, Anupama Rao, Paul Veys, Giovanna Lucchini, Robert Chiesa, Kanchan Rao, Persis J Amrolia, Sara Ghorashian
Journal: Blood
Blood (2021) 138 (Supplement 1): 3859.
https://doi.org/10.1182/blood-2021-152344
Published: 2021
Journal Articles

Blinatumomab for infant acute lymphoblastic leukemia

Clinical Trials & Observations
Katherine Clesham, Vasudha Rao, Jack Bartram, Philip Ancliff, Sara Ghorashian, David O’Connor, Vesna Pavasovic, Anupama Rao, Sujith Samarasinghe, Michelle Cummins, Andrea Malone, Katharine Patrick, Denise Bonney, Beki James, Brenda Gibson, Ajay Vora
Journal: Blood
Blood (2020) 135 (17): 1501–1504.
https://doi.org/10.1182/blood.2019004008
Published: 2020
Journal Articles

Excellent Response to Blinatumomab in Children and Young Adults with Refractory B Lineage Acute Lymphoblastic Leukaemia for Persistent MRD or after Debulking Chemotherapy for Higher Disease Burden

Vasudha Rao, MD, Katherine Clesham, Jack Luke Bartram, MD, Phil Ancliff, Sara Ghorashian, FRCPath, PhD, David O'Connor, Vesna Pavasovic, Anupama Rao, MD, Sujith Samarasinghe, Carole Cairns, David Marks, David Taussig, PhD MRCP, FRCPath, Ajay Vora, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5201.
https://doi.org/10.1182/blood-2018-99-117051
Published: 2018