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Journal Articles

Specific Pharmacologic Targeting of Rho GTPases Rac1, Cdc42 and RhoA Reveals Their Differential and Critical Roles In Regulation of Platelet Activation

Huzoor Akbar, PhD, Xun Shang, PhD, Rehana Perveen, PhD, Kevin Funk, MS, Mark Berryman, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2010) 116 (21): 2019.
https://doi.org/10.1182/blood.V116.21.2019.2019
Published: 2010
Journal Articles

Genetic and Pharmacologic Evidence Shows That Cdc42 GTPase Plays a Central Role in the Regulation of Both GPVI- and Non-GPVI-Dependent Activation of Platelets.

Huzoor Akbar, PhD, Kevin Funk, MS, Mark Berryman, PhD, Joshua Raines, BS, Rehana Perveen, PhD, Xun Shang, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2009) 114 (22): 2997.
https://doi.org/10.1182/blood.V114.22.2997.2997
Published: 2009
Journal Articles

Mobilization of Hematopoitic Stem/Progenitor Cells by a Cdc42 Activity-Specific Inhibitor

Wei Liu, MD, MS, Lei Wang, PhD, Xun Shang, PhD, Fukun Guo, PhD, Marnie A. Ryan, PhD, Hartmut Geiger, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2008) 112 (11): 68.
https://doi.org/10.1182/blood.V112.11.68.68
Published: 2008
Journal Articles

A Cell-Autonomous Defect of Bone Marrow Hematopoietic Stem/Progenitor Cells and Impaired Stromal Function in FA-a Patients

Xiaoling Zhang, Xun Shang, Fukun Guo, Kim Murphy, Michelle Kirby, Patrick Kelly, Lilith Reeves, Franklin O Smith, David A. Williams, Yi Zheng, Qishen Pang
Journal: Blood
Blood (2008) 112 (11): 1364.
https://doi.org/10.1182/blood.V112.11.1364.1364
Published: 2008
Journal Articles

Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A

Brief Report
Xiaoling Zhang, Xun Shang, Fukun Guo, Kim Murphy, Michelle Kirby, Patrick Kelly, Lilith Reeves, Franklin O. Smith, David A. Williams, Yi Zheng, Qishen Pang
Journal: Blood
Blood (2008) 112 (5): 1683–1686.
https://doi.org/10.1182/blood-2008-03-147090
Published: 2008
Includes: Supplemental data
Journal Articles

Cdc42 critically regulates the balance between myelopoiesis and erythropoiesis

Linda Yang, Lei Wang, Theodosia A. Kalfa, Jose A. Cancelas, Xun Shang, Suvarnamala Pushkaran, Jun Mo, David A. Williams, Yi Zheng
Journal: Blood
Blood (2007) 110 (12): 3853–3861.
https://doi.org/10.1182/blood-2007-03-079582
Published: 2007
Journal Articles

R-Ras Regulates Hematopoietic Stem/Progenitor Cell Adhesion, Migration, and Mobilization through Rac GTPase-Mediated Signals.

Xun Shang, PhD, Lina Li, MD, Jose Concelas, MD PhD, Fukun Guo, PhD, Deidre Daria, MS, Hartmut Geiger, MD, Nancy Ratner, MD, Yi Zheng, PhD
Journal: Blood
Blood (2007) 110 (11): 221.
https://doi.org/10.1182/blood.V110.11.221.221
Published: 2007
Journal Articles

Defective Adhesion, Migration and Homing Are Associated with Altered Rho GTPase Activity in Cells from Fanconi Anemia Patients.

Xiaoling Zhang, MD, Xun Shang, PhD, Lei Wang, PhD, Fukun Guo, PhD, Yi Zheng, PhD, Qishen Pang, PhD
Journal: Blood
Blood (2006) 108 (11): 350.
https://doi.org/10.1182/blood.V108.11.350.350
Published: 2006