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Journal Articles

Identification of T-Cell Receptors Specific to Antigens Presented By HLA-B4002 and B5401 in Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Eiji Kobayashi, PhD, Yoshiki Akatsuka, MD PhD, Luis Espinoza, MD PhD, Noriharu Nakagawa, MD, Tanabe Mikoto, MD, Noriaki Tsuji, MD, Takeshi Yoroidaka, MD, Hiroki Mizumaki, MD, Thi Mai Anh Nguyen, MD, Takamasa Katagiri, PhD, Kiyomi Shitaoka, PhD, Hiroshi Hamana, PhD, Hiroyuki Kishi, PhD, Shinji Nakao, MD PhD

Blood (2019) 134 (Supplement_1): 3751.

https://doi.org/10.1182/blood-2019-125685

Published: 2019

Journal Articles

Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination

Yasushi Akahori, Linan Wang, Motohiro Yoneyama, Naohiro Seo, Satoshi Okumura, Yoshihiro Miyahara, Yasunori Amaishi, Sachiko Okamoto, Junichi Mineno, Hiroaki Ikeda, Takehiro Maki, Hiroshi Fujiwara, Yoshiki Akatsuka, Takuma Kato, Hiroshi Shiku

Blood (2018) 132 (11): 1134–1145.

https://doi.org/10.1182/blood-2017-08-802926

Published: 2018

Includes: Supplemental data

Journal Articles

Identification of T Cell Receptors Specific to Antigens Presented By HLA-B5401 on IPS Cell-Derived Hematopoietic Stem Cells in a Patient with Acquired Aplastic Anemia Carrying B5401-Lacking Leukocytes

Noriharu Nakagawa, MD, Mahmoud Ibrahim Elbadry, MD, Yoshiki Akatsuka, MD, Hiroshi Hamana, Kiyomi Shitaoka, Yoshinori Yoshida, MD PhD, Kazuhisa Chonabayashi, MD PhD, Tatsuya Imi, MD, Yoshitaka Zaimoku, MD, Katsuto Takenaka, Hiroshi Fujiwara, MD PhD, Hiroyuki Kishi, PhD, Shinji Nakao, MD PhD

Blood (2017) 130 (Supplement 1): 2458.

https://doi.org/10.1182/blood.V130.Suppl_1.2458.2458

Published: 2017

Journal Articles

Safety and persistence of WT1-specific T-cell receptor gene−transduced lymphocytes in patients with AML and MDS

Blood (2017) 130 (18): 1985–1994.

https://doi.org/10.1182/blood-2017-06-791202

Published: 2017

Includes: Supplemental data

Journal Articles

Phase 1 Clinical Trial of Adoptive Immunotherapy for Acute Myelogenous Leukemia and Myelodysplastic Syndrome, Using Gene-Modified Autologous Lymphocytes Expressing WT1-Specific T-Cell Receptor

Kazushi Tanimoto, MD PhD, Hiroshi Fujiwara, MD PhD, Isao Tawara, MD PhD, Masahiro Masuya, MD PhD, Shinichi Kageyama, MD PhD, Tetsuya Nishida, MD PhD, Makoto Murata, MD PhD, Seitaro Terakura, MD PhD, Yoshiki Akatsuka, MD PhD, Hiroaki Ikeda, MD PhD, Yoshihiro Miyahara, MD PhD, Ikuei Nukaya, PhD, Kazutoh Takesako, PhD, Nobuhiko Emi, MD PhD, Naoyuki Katayama, MD PhD, Hiroshi Shiku, MD PhD, Masaki Yasukawa, MD PhD

Blood (2016) 128 (22): 1653.

https://doi.org/10.1182/blood.V128.22.1653.1653

Published: 2016

Journal Articles

Genome-wide surveillance of mismatched alleles for graft-versus-host disease in stem cell transplantation

Aiko Sato-Otsubo, Yasuhito Nannya, Koichi Kashiwase, Makoto Onizuka, Fumihiro Azuma, Yoshiki Akatsuka, Yasuko Ogino, Masahiro Satake, Masashi Sanada, Shigeru Chiba, Hiroh Saji, Hidetoshi Inoko, Giulia C. Kennedy, Ken Yamamoto, Satoko Morishima, Yasuo Morishima, Yoshihisa Kodera, Takehiko Sasazuki, Seishi Ogawa

Blood (2015) 126 (25): 2752–2763.

https://doi.org/10.1182/blood-2015-03-630707

Published: 2015

Includes: Supplemental data

Journal Articles

Adoptive Transfer of WT1-Specific TCR Gene-Transduced Lymphocytes in Patients with Myelodysplastic Syndrome and Acute Myeloid Leukemia

Isao Tawara, MD PhD, Masahiro Masuya, MD PhD, Shinichi Kageyama, MD PhD, Tetsuya Nishida, MD PhD, Seitaro Terakura, MD PhD, Makoto Murata, MD PhD, Hiroshi Fujiwara, MD PhD, Yoshiki Akatsuka, MD PhD, Hiroaki Ikeda, MD PhD, Yoshihiro Miyahara, MD PhD, Daisuke Tomura, PhD, Ikuei Nukaya, PhD, Kazutoh Takesako, PhD, Nobuhiko Emi, MDPhD, Masaki Yasukawa, MD PhD, Naoyuki Katayama, MD PhD, Hiroshi Shiku, MD PhD

Blood (2015) 126 (23): 97.

https://doi.org/10.1182/blood.V126.23.97.97

Published: 2015

Journal Articles

A Varicella Outbreak in Diffuse Large B-Cell Lymphoma Patients Receiving Rituximab-Containing Chemotherapy

Akinao Okamoto, MD, Akihiro Abe, MD PhD, Masataka Okamoto, Yoko Inaguma, MD, Tokuda Masutaka, MDPhD, Satoko Morishima, MD, PhD, Masamitsu Yanada, Tadaharu Kanie, MDPhD, Yukiya Yamamoto, MD PhD, Shuichi Mizuta, MD PhD, Yoshiki Akatsuka, MD PhD, Tetsushi Yoshikawa, MDPhD, Nobuhiko Emi, MDPhD

Blood (2014) 124 (21): 5439.

https://doi.org/10.1182/blood.V124.21.5439.5439

Published: 2014

Journal Articles

Construction and Molecular Characterization Of a T-Cell Receptor-Like Antibody and CAR-T Cells Specific For Minor Histocompatibility Antigen HA-1H

Yoko Inaguma, MD, Yasushi Akahori, PhD, Yoshiki Akatsuka, MD, PhD, Yuko Murayama, Keiko Shiraishi, Sachiko Tsuzuki-Iba, Akemi Endoh, Juri Tsujikawa, Ayako Demachi-Okamura, PhD, Kaho Hiramatsu, Hiroh Saji, PhD, Yukiya Yamamoto, MD, PhD, Naoki Yamamoto, PhD, Nishimura Yasuharu, MD, PhD, Toshitada Takahashi, MD, PhD, Kiyotaka Kuzushima, MD, PhD, Nobuhiko Emi, MD, PhD

Blood (2013) 122 (21): 4490.

https://doi.org/10.1182/blood.V122.21.4490.4490

Published: 2013

Journal Articles

Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen

Sebastian Ochsenreither, Ravindra Majeti, Thomas Schmitt, Derek Stirewalt, Ulrich Keilholz, Keith R. Loeb, Brent Wood, Yongiae E. Choi, Marie Bleakley, Edus H. Warren, Michael Hudecek, Yoshiki Akatsuka, Irving L. Weissman, Philip D. Greenberg

Blood (2012) 119 (23): 5492–5501.

https://doi.org/10.1182/blood-2011-07-365890

Published: 2012

Includes: Supplemental data

Journal Articles

Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens

Edus H. Warren, Nobuharu Fujii, Yoshiki Akatsuka, Colette N. Chaney, Jeffrey K. Mito, Keith R. Loeb, Ted A. Gooley, Michele L. Brown, Kevin K. W. Koo, Kellie V. Rosinski, Seishi Ogawa, Aiko Matsubara, Frederick R. Appelbaum, Stanley R. Riddell

Blood (2010) 115 (19): 3869–3878.

https://doi.org/10.1182/blood-2009-10-248997

Published: 2010

Includes: Supplemental data

Journal Articles

Relapse of leukemia with loss of mismatched HLA resulting from uniparental disomy after haploidentical hematopoietic stem cell transplantation

Itzel Bustos Villalobos, Yoshiyuki Takahashi, Yoshiki Akatsuka, Hideki Muramatsu, Nobuhiro Nishio, Asahito Hama, Hiroshi Yagasaki, Hiroh Saji, Motohiro Kato, Seishi Ogawa, Seiji Kojima

Blood (2010) 115 (15): 3158–3161.

https://doi.org/10.1182/blood-2009-11-254284

Published: 2010

Includes: Supplemental data

Journal Articles

Relapse of Leukemia with Loss of Mismatched HLA Due to Uniparentaldisomy Follwing Haploidentical Hematopoietic Transplantation.

Yoshiyuki Takahashi, Itzel Bustos, Yoshiki Akatsuka, Hideki Muramatsu, Nobuhiro Nishio, Asahito Hama, Hiroshi Yagasaki, Hiroh Saji, Motohiro Kato, Seishi Ogawa, Seiji Kojima

Blood (2009) 114 (22): 2457.

https://doi.org/10.1182/blood.V114.22.2457.2457

Published: 2009

Journal Articles

Aberrations of Genes Regulating NF Kappa B Pathway in B-Cell Malignant Lymphoma.

Blood (2009) 114 (22): 971.

https://doi.org/10.1182/blood.V114.22.971.971

Published: 2009

Journal Articles

HapMap scanning of novel human minor histocompatibility antigens

Blood (2009) 113 (21): 5041–5048.

https://doi.org/10.1182/blood-2008-07-171678

Published: 2009

Includes: Supplemental data

Journal Articles

Genome-Wide Association Studies of Genetic Incompatibility That Is Relevant to the Development of GvHD in Unrelated Bone Marrow Transplantation

Seishi Ogawa, MD, PhD, Aiko Matsubara, PhD, Koichi Kashiwase, PhD, Makoto Onizuka, MD, PhD, Masashi Sanada, MD, Motohiro Kato, MD, Yasuhito Nannya, MD, PhD, Yoshiki Akatsuka, MD, PhD, Takakazu Kawase, MD, PhD, Masahiro Satake, MD, PhD, Junko Takita, MD, Yasuo Morishima, MD, PhD, Shigeru Chiba, MD, PhD, Hiroo Saji, MD, PhD, Hidetoshi Inoko, MD, PhD, Yoshihisa Kodera, MD, Takehiko Sasazuki, MD, PhD

Blood (2008) 112 (11): 715.

https://doi.org/10.1182/blood.V112.11.715.715

Published: 2008

Journal Articles

HapMap Scanning of Novel Human Minor Histocompatibility Antigens

Yasuhito Nannya, MD, PhD, Michi Kamei, MD, PhD, Hiroki Torikai, MD, PhD, Takakazu Kawase, MD, PhD, Kenjiro Taura, PhD, Yoshihiro Inamoto, MD, PhD, Taro Takahashi, MD, PhD, Makoto Yazaki, MD, PhD, Satoko Morishima, MD, PhD, Koichi Miyamura, MD, PhD, Tetsuya Ito, MD, PhD, Yoshihisa Kodera, MD, Yasuo Morishima, MD, Toshitada Takahashi, MD, Kiyotaka Kuzushima, MD, Seishi Ogawa, MD, PhD, Yoshiki Akatsuka, MD, PhD

Blood (2008) 112 (11): 3908.

https://doi.org/10.1182/blood.V112.11.3908.3908

Published: 2008

Journal Articles

DDX3Y encodes a class I MHC–restricted H-Y antigen that is expressed in leukemic stem cells

Kellie V. Rosinski, Nobuharu Fujii, Jeffrey K. Mito, Kevin K. W. Koo, Suzanne M. Xuereb, Olga Sala-Torra, James S. Gibbs, Jerald P. Radich, Yoshiki Akatsuka, Benoît J. Van den Eynde, Stanley R. Riddell, Edus H. Warren

Blood (2008) 111 (9): 4817–4826.

https://doi.org/10.1182/blood-2007-06-096313

Published: 2008

Journal Articles

Identification of human minor histocompatibility antigens based on genetic association with highly parallel genotyping of pooled DNA

Takakazu Kawase, Yasuhito Nannya, Hiroki Torikai, Go Yamamoto, Makoto Onizuka, Satoko Morishima, Kunio Tsujimura, Koichi Miyamura, Yoshihisa Kodera, Yasuo Morishima, Toshitada Takahashi, Kiyotaka Kuzushima, Seishi Ogawa, Yoshiki Akatsuka

Blood (2008) 111 (6): 3286–3294.

https://doi.org/10.1182/blood-2007-10-118950

Published: 2008

Includes: Supplemental data

Journal Articles

Escape of Minor Histocompatibility Antigen-Restricted Anti-Leukemia Immunity Associated with Loss of Specific HLA-I Locus Expression in a Leukemia Patient after an Intensive Immunotherapy.

Lung-Ji Chang, PhD, Chun-Rong Tong, MD, Jih-Luh Tang, MD PhD, Yoshiki Akatsuka, MD PhD, Shuhong Han, PhD, Yin Liang, MSc, Chi-Cheng Li, MD, Lujia Dong, MD, Tong Wu, MD, Dao-Pei Lu, MD

Blood (2007) 110 (11): 4895.

https://doi.org/10.1182/blood.V110.11.4895.4895

Published: 2007

NARROW

Identification of T-Cell Receptors Specific to Antigens Presented By HLA-B4002 and B5401 in Acquired Aplastic Anemia

Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination

Identification of T Cell Receptors Specific to Antigens Presented By HLA-B5401 on IPS Cell-Derived Hematopoietic Stem Cells in a Patient with Acquired Aplastic Anemia Carrying B5401-Lacking Leukocytes

Safety and persistence of WT1-specific T-cell receptor gene−transduced lymphocytes in patients with AML and MDS

Phase 1 Clinical Trial of Adoptive Immunotherapy for Acute Myelogenous Leukemia and Myelodysplastic Syndrome, Using Gene-Modified Autologous Lymphocytes Expressing WT1-Specific T-Cell Receptor

Genome-wide surveillance of mismatched alleles for graft-versus-host disease in stem cell transplantation

Adoptive Transfer of WT1-Specific TCR Gene-Transduced Lymphocytes in Patients with Myelodysplastic Syndrome and Acute Myeloid Leukemia

A Varicella Outbreak in Diffuse Large B-Cell Lymphoma Patients Receiving Rituximab-Containing Chemotherapy

Construction and Molecular Characterization Of a T-Cell Receptor-Like Antibody and CAR-T Cells Specific For Minor Histocompatibility Antigen HA-1H

Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen

Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens

Relapse of leukemia with loss of mismatched HLA resulting from uniparental disomy after haploidentical hematopoietic stem cell transplantation

Relapse of Leukemia with Loss of Mismatched HLA Due to Uniparentaldisomy Follwing Haploidentical Hematopoietic Transplantation.

Aberrations of Genes Regulating NF Kappa B Pathway in B-Cell Malignant Lymphoma.

HapMap scanning of novel human minor histocompatibility antigens

Genome-Wide Association Studies of Genetic Incompatibility That Is Relevant to the Development of GvHD in Unrelated Bone Marrow Transplantation

HapMap Scanning of Novel Human Minor Histocompatibility Antigens

DDX3Y encodes a class I MHC–restricted H-Y antigen that is expressed in leukemic stem cells

Identification of human minor histocompatibility antigens based on genetic association with highly parallel genotyping of pooled DNA

Escape of Minor Histocompatibility Antigen-Restricted Anti-Leukemia Immunity Associated with Loss of Specific HLA-I Locus Expression in a Leukemia Patient after an Intensive Immunotherapy.

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American Society of Hematology

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American Society of Hematology

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