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Journal Articles

GPIbα–filamin A interaction regulates megakaryocyte localization and budding during platelet biogenesis

Marc L. Ellis, Antoine Terreaux, Imala Alwis, Rhyll Smythe, Jose Perdomo, Anita Eckly, Susan L. Cranmer, Freda H. Passam, Jessica Maclean, Simone M. Schoenwaelder, Zaverio M. Ruggeri, Francois Lanza, Samir Taoudi, Yuping Yuan, Shaun P. Jackson

Blood (2024) 143 (4): 342–356.

https://doi.org/10.1182/blood.2023021292

Published: 2024

Includes: Supplemental data

Journal Articles

Pathogen Reduced Cryoprecipitated Fibrinogen Complex (IFC) and Cryoprecipitated AHF Contain Von Willebrand Factor with Comparable Binding to Collagen and Support Shear-Induced Platelet Thrombus Formation

Subramanian Yegneswaran, Alessandro Zarpellon, Jennifer N Orje, Michelle Gatmaitan, Nina Mufti, Laurence Corash, Zaverio M Ruggeri

Blood (2023) 142 (Supplement 1): 4039.

https://doi.org/10.1182/blood-2023-187124

Published: 2023

Journal Articles

Mechanisms of anti-GPIbα antibody–induced thrombocytopenia in mice

Yosuke Morodomi, Sachiko Kanaji, Eric Won, Zaverio M. Ruggeri, Taisuke Kanaji

Blood (2020) 135 (25): 2292–2301.

https://doi.org/10.1182/blood.2019003770

Published: 2020

Includes: Supplemental data

Journal Articles

Cardiac Myosin Acts Is a Potent Procoagulant in Vitro and In Vivo

Jevgenia Zilberman-Rudenko, Hiroshi Deguchi, MD PhD, Mohammed Hayat, Meenal Shukla, PhD, Jennifer Nagrampa Orje, Zihan Guo, Tine Wyseure, PhD, Laurent O Mosnier, Owen J T McCarty, PhD, Zaverio M. Ruggeri, MD, John H. Griffin, PhD

Blood (2019) 134 (Supplement_1): 3632.

https://doi.org/10.1182/blood-2019-129312

Published: 2019

Journal Articles

Defective Platelet Thromboxane A2 Signaling and Serotonin Release in the Pathogenesis of Bleeding during Viral Infection

Roberto Aiolfi, PhD, Giovanni Sitia, Matteo Iannacone, Luca Guidotti, Zaverio M. Ruggeri, MD

Blood (2019) 134 (Supplement_1): 1074.

https://doi.org/10.1182/blood-2019-128940

Published: 2019

Journal Articles

Sca-1 As a Marker of Stress-Induced Thrombopoiesis in Mice

Yosuke Morodomi, MD PhD, Roberto Aiolfi, PhD, Eric Won, MD, Sachiko Kanaji, MD PhD, Paul Schimmel, PhD, Zaverio M. Ruggeri, MD, Taisuke Kanaji, MD

Blood (2019) 134 (Supplement_1): 1068.

https://doi.org/10.1182/blood-2019-127446

Published: 2019

Journal Articles

A Novel Anti-Glycoprotein (GP) Iba-Targeting Chimeric Fibrinolytic Agent Demonstrates In Vivo Efficacy Against Human Platelet-Enriched Thrombi in Mice

Randolph Lyde, PhD, Hyunsook Ahn, Vincent Hayes, Sergei Zaistev, PhD, Shu-Wha Lin, PhD, Zaverio M. Ruggeri, MD, Renhao Li, PhD, Vladimir Muzykantov, Douglas B. Cines, MD, Mortimer Poncz, MD

Blood (2018) 132 (Supplement 1): 990.

https://doi.org/10.1182/blood-2018-99-115262

Published: 2018

Journal Articles

GPIbα is required for platelet-mediated hepatic thrombopoietin generation

Miao Xu, June Li, Miguel Antonio Dias Neves, Guangheng Zhu, Naadiya Carrim, Ruoying Yu, Sahil Gupta, John Marshall, Ori Rotstein, Jun Peng, Ming Hou, Shinji Kunishima, Jerry Ware, Donald R. Branch, Alan H. Lazarus, Zaverio M. Ruggeri, John Freedman, Heyu Ni

Blood (2018) 132 (6): 622–634.

https://doi.org/10.1182/blood-2017-12-820779

Published: 2018

Includes: Supplemental data

Journal Articles

14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling

Yunfeng Chen, Zaverio M. Ruggeri, Xiaoping Du

Blood (2018) 131 (22): 2436–2448.

https://doi.org/10.1182/blood-2017-09-742650

Published: 2018

Journal Articles

Expression of Functional Human Proteinase Activated Receptor (PAR)-1 on Mouse Platelets

Alessandro Zarpellon, PhD, Taisuke Kanaji, MD, Sachiko Kanaji, MD PhD, Yosuke Morodomi, MD PhD, Zaverio M. Ruggeri, MD

Blood (2017) 130 (Supplement 1): 451.

https://doi.org/10.1182/blood.V130.Suppl_1.451.451

Published: 2017

Journal Articles

Identification of a VWFA1 Mutation Attenuating Thrombus Growth but Not Platelet Adhesion

Yunfeng Chen, PhD, James R. Roberts, Jennifer Nagrampa Orje, Yosuke Morodomi, MD PhD, Taisuke Kanaji, MD, Sachiko Kanaji, MD PhD, Zaverio M. Ruggeri, MD

Blood (2017) 130 (Supplement 1): 547.

https://doi.org/10.1182/blood.V130.Suppl_1.547.547

Published: 2017

Journal Articles

Selective factor VIII activation by the tissue factor–factor VIIa–factor Xa complex

Yuichi Kamikubo, G. Loredana Mendolicchio, Antonella Zampolli, Patrizia Marchese, Andrea S. Rothmeier, Jennifer Nagrampa Orje, Andrew J. Gale, Sriram Krishnaswamy, András Gruber, Henrik Østergaard, Lars C. Petersen, Wolfram Ruf, Zaverio M. Ruggeri

Blood (2017) 130 (14): 1661–1670.

https://doi.org/10.1182/blood-2017-02-767079

Published: 2017

Includes: Supplemental data

Journal Articles

Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2

Blood (2017) 130 (4): 542–553.

https://doi.org/10.1182/blood-2016-11-754416

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

Extracellular Tyrosyl-tRNA Synthetase Is a Potent Stimulator of Thrombocytopoiesis

Sachiko Kanaji, MD PhD, Taisuke Kanaji, MD PhD, My-Nuong Vo, PhD, Alessandro Zarpellon, PhD, Ryan Shapiro, Rajesh Belani, MD, Minh-Ha Do, PhD, Xiang-Lei Yang, PhD, Zaverio M. Ruggeri, MD, Paul Schimmel, PhD

Blood (2016) 128 (22): 1476.

https://doi.org/10.1182/blood.V128.22.1476.1476

Published: 2016

Journal Articles

Humanized Von Willebrand Factor-Glycoprotein Ibα Interaction in Mouse Models of Hemostasis and Thrombosis

Sachiko Kanaji, MD PhD, Jennifer N Orje, Yuichi Kamikubo, PhD, Taisuke Kanaji, MD PhD, Jeremy Mattson, Alessandro Zarpellon, PhD, Scot A. Fahs, Rashmi Sood, PhD, Sandra L Haberichter, PhD, Zaverio M. Ruggeri, MD, Robert R Montgomery, MD

Blood (2016) 128 (22): 558.

https://doi.org/10.1182/blood.V128.22.558.558

Published: 2016

Journal Articles

Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va

Hiroshi Deguchi, Ranjeet K. Sinha, Patrizia Marchese, Zaverio M. Ruggeri, Jevgenia Zilberman-Rudenko, Owen J. T. McCarty, Mitchell J. Cohen, John H. Griffin

Blood (2016) 128 (14): 1870–1878.

https://doi.org/10.1182/blood-2016-03-707679

Published: 2016

Includes: Supplemental data

Journal Articles

Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activation

Brian Estevez, Kyungho Kim, M. Keegan Delaney, Aleksandra Stojanovic-Terpo, Bo Shen, Changgeng Ruan, Jaehyung Cho, Zaverio M. Ruggeri, Xiaoping Du

Blood (2016) 127 (5): 626–636.

https://doi.org/10.1182/blood-2015-04-638387

Published: 2016

Includes: Multimedia, Supplemental data

Journal Articles

Platelet-Localized FXI Promotes a Glycoprotein Ib Alpha Dependent Feedback Loop in Arterial Hypertension and Vascular Inflammation

Blood (2015) 126 (23): 2192.

https://doi.org/10.1182/blood.V126.23.2192.2192

Published: 2015

Journal Articles

Platelet GPIb: sensing force and responding

Zaverio M. Ruggeri

Blood (2015) 125 (3): 423–424.

https://doi.org/10.1182/blood-2014-12-610642

Published: 2015

Journal Articles

Distinct Mechanism of Anti-Hemophilic FVIII Activation By Nascent FXa in the Tissue Factor-FVIIa Coagulation Initiation Complex Resistant to FXa-Directed Inhibition

Yuichi Kamikubo, PhD, Grazia Loredana Mendolicchio, MD PhD, Antonella Zampolli, PhD, Patrizia Marchese, PhD, Andrew J. Gale, PhD, Sriram Krishnaswamy, PhD, Andras Gruber, MD, Lars Christian Petersen, Wolfram Ruf, MD, Zaverio M Ruggeri, MD

Blood (2014) 124 (21): 2803.

https://doi.org/10.1182/blood.V124.21.2803.2803

Published: 2014

NARROW

GPIbα–filamin A interaction regulates megakaryocyte localization and budding during platelet biogenesis

Pathogen Reduced Cryoprecipitated Fibrinogen Complex (IFC) and Cryoprecipitated AHF Contain Von Willebrand Factor with Comparable Binding to Collagen and Support Shear-Induced Platelet Thrombus Formation

Mechanisms of anti-GPIbα antibody–induced thrombocytopenia in mice

Cardiac Myosin Acts Is a Potent Procoagulant in Vitro and In Vivo

Defective Platelet Thromboxane A2 Signaling and Serotonin Release in the Pathogenesis of Bleeding during Viral Infection

Sca-1 As a Marker of Stress-Induced Thrombopoiesis in Mice

A Novel Anti-Glycoprotein (GP) Iba-Targeting Chimeric Fibrinolytic Agent Demonstrates In Vivo Efficacy Against Human Platelet-Enriched Thrombi in Mice

GPIbα is required for platelet-mediated hepatic thrombopoietin generation

14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling

Expression of Functional Human Proteinase Activated Receptor (PAR)-1 on Mouse Platelets

Identification of a VWFA1 Mutation Attenuating Thrombus Growth but Not Platelet Adhesion

Selective factor VIII activation by the tissue factor–factor VIIa–factor Xa complex

Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2

Extracellular Tyrosyl-tRNA Synthetase Is a Potent Stimulator of Thrombocytopoiesis

Humanized Von Willebrand Factor-Glycoprotein Ibα Interaction in Mouse Models of Hemostasis and Thrombosis

Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va

Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activation

Platelet-Localized FXI Promotes a Glycoprotein Ib Alpha Dependent Feedback Loop in Arterial Hypertension and Vascular Inflammation

Platelet GPIb: sensing force and responding

Distinct Mechanism of Anti-Hemophilic FVIII Activation By Nascent FXa in the Tissue Factor-FVIIa Coagulation Initiation Complex Resistant to FXa-Directed Inhibition

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American Society of Hematology

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ASH Publications

American Society of Hematology

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