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Journal Articles

Safety and efficacy of an anti–human APC antibody for prophylaxis of congenital factor deficiencies in preclinical models

Miao Jiang, Fei Yang, Yizhi Jiang, Lu Cheng, Jingjing Han, Jiawei Yi, Bin Zuo, Lulu Huang, Zhenni Ma, Tianyi Li, Lijuan J. Cao, Zhisong Xia, Xia Bai, Chenjun Jia, Teddy Tat Chi Yang, Naomi L. Esmon, Changgeng Ruan, Lijun Xia, Charles T. Esmon, Yue Han, Depei Wu, Jun Xu
Journal: Blood
Blood (2023) 142 (12): 1071–1081.
https://doi.org/10.1182/blood.2023020005
Published: 2023
Includes: Supplemental data
Journal Articles

A Novel Monoclonal Antibody Against A2 Domain of Von Willebrand Factor Reduces Its Proteolysis By ADAMTS13

Lulu Zhang, Jian Su, Fei Shen, Zhenni MA, Yiming Zhao, Ziqiang Yu, Changgeng Ruan
Journal: Blood
Blood (2016) 128 (22): 2575.
https://doi.org/10.1182/blood.V128.22.2575.2575
Published: 2016
Journal Articles

Alterations of Plasma Complement C3b, C5b and VWF, ADAMTS13 in Patients with Graft-Versus-Host Disease and Thrombotic Microangiopathy after Hematopoietic Stem-Cell Transplantation

Yue Han, MD, Jie Wang, Jia Chen, Jiaqian Qi, Jian Su, Zhenni Ma, Yaqiong Tang, Wei Han, Aining Sun, PhD, Zhaoyue Wang, Changgeng Ruan, MD, PhD, Wu Depei, MD
Journal: Blood
Blood (2015) 126 (23): 3143.
https://doi.org/10.1182/blood.V126.23.3143.3143
Published: 2015
Journal Articles

Mutations in the D1 Domain Inhibit Propeptide-Dependent Multimerization, Trafficking and Regulated Secretion of Von Willebrand Factor in VWD

Jie Yin, Zhenni Ma, Jian Su, Xiaojuan Zhao, Zhaoyue Wang, Ziqiang Yu, Wanyan Ouyang, Xia Bai, Changgeng Ruan
Journal: Blood
Blood (2014) 124 (21): 1495.
https://doi.org/10.1182/blood.V124.21.1495.1495
Published: 2014
Journal Articles

Changes of ADAMTS13 Activity and VWF Level in the Plasma of Patients Undergoing Hematopoietic Stem-Cell Transplantation (HSCT)

Yue Han, Luping HU, Qian Zhu, Yang Xu, Xiaohui Hu, Jian Su, Zhenni Ma, Wei Zhang, Aining Sun, Huiying Qiu, Zhaoyue Wang, MD, Changgeng Ruan, MD, PhD, Wu Depei
Journal: Blood
Blood (2012) 120 (21): 3329.
https://doi.org/10.1182/blood.V120.21.3329.3329
Published: 2012
Journal Articles

Simvastatin Improve ADAMTS13 mRNA and Protein Expression in Podocytes.

Lei Shen, MS, Guoyuan Lu, MD, Ningzheng Dong, PhD, Zhenni Ma, MS, Changgeng Ruan, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2246.
https://doi.org/10.1182/blood.V120.21.2246.2246
Published: 2012
Journal Articles

The Co-Influence of VWD Type 2B and Type 2M Mutations and Platelet GPIbα On the Susceptibility of VWF to ADAMTS13 Under Shear Stress

Zhenni Ma, Jingyu Zhang, MD, PhD, Jian Su, Jing Ling, Changgeng Ruan, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1108.
https://doi.org/10.1182/blood.V120.21.1108.1108
Published: 2012
Journal Articles

The W–x–x–W Motif in the TSR1 of ADAMTS13 Is Important for Its Secretion

Jing Ling, Jian Su, Zhenni Ma, Changgeng Ruan, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 4389.
https://doi.org/10.1182/blood.V120.21.4389.4389
Published: 2012
Journal Articles

Von Willebrand Factor, ADAMTS13 Activity, TNF-Alpha, and Their Relationships in Patients with Chronic Kidney Disease

Lei Shen, MS, Guoyuan Lu, Ph.D, Ningzheng Dong, Ph.D, Liqiong Jiang, MS, Zhenni Ma, MS, Changgeng Ruan
Journal: Blood
Blood (2011) 118 (21): 5312.
https://doi.org/10.1182/blood.V118.21.5312.5312
Published: 2011
Journal Articles

All-Trans Retinoic Acid Modulates the Balance of ADAMTS13 and VWF In Human Microvascular Endothelial Cells

Anyou Wang, Ziqiang Yu, Ningzheng Dong, Zhenni Ma, Jingyu Zhang, Changgeng Ruan, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4424.
https://doi.org/10.1182/blood.V116.21.4424.4424
Published: 2010
Journal Articles

Thrombospondin-1 and ADAMTS13 Competitive Binding with VWF Mainly in Both A2 and A3 Domain.

Anyou Wang, Ningzheng Dong, Zhenni Ma, Jingyu Zhang, Jian Su, Changgeng Ruan, MD, PHD
Journal: Blood
Blood (2009) 114 (22): 4008.
https://doi.org/10.1182/blood.V114.22.4008.4008
Published: 2009
Journal Articles

Epitope Mapping of a Monoclonal Antibody against VWF Which Diminishes the Proteolytic Cleavage of VWF by ADAMTS13 Under Flow.

Jingyu Zhang, Zhenni Ma, Ningzheng Dong, PhD, Jian Su, Anyou Wang, Changgeng Ruan, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2133.
https://doi.org/10.1182/blood.V114.22.2133.2133
Published: 2009
Journal Articles

Evaluation and Clinical Application of a New Method for Detecting ADAMTS13 Activity.

Anyou Wang, Ningzheng Dong, Zhenni Ma, Jingyu Zhang, Jian Su, Changgeng Ruan, MD, PHD
Journal: Blood
Blood (2009) 114 (22): 2134.
https://doi.org/10.1182/blood.V114.22.2134.2134
Published: 2009
Journal Articles

The Expression of MT1-MMP in Human Hematopoietic Cell Lines and Its Influences on the Biological Behaviors of HL60.

Juxiang Jiang, MD,PhD, Zhenni Ma, Ningzheng Dong, MD,PhD, Xia Bai, Changgeng Ruan, MD,PhD
Journal: Blood
Blood (2007) 110 (11): 4123.
https://doi.org/10.1182/blood.V110.11.4123.4123
Published: 2007