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Naomi L. Esmon
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Journal Articles

Safety and efficacy of an anti–human APC antibody for prophylaxis of congenital factor deficiencies in preclinical models

Miao Jiang, Fei Yang, Yizhi Jiang, Lu Cheng, Jingjing Han, Jiawei Yi, Bin Zuo, Lulu Huang, Zhenni Ma, Tianyi Li, Lijuan J. Cao, Zhisong Xia, Xia Bai, Chenjun Jia, Teddy Tat Chi Yang, Naomi L. Esmon, Changgeng Ruan, Lijun Xia, Charles T. Esmon, Yue Han, Depei Wu, Jun Xu
Journal: Blood
Blood (2023) 142 (12): 1071–1081.
https://doi.org/10.1182/blood.2023020005
Published: 2023
Includes: Supplemental data
Journal Articles

Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice

Maureen A. Shaw, Keith W. Kombrinck, Kathryn E. McElhinney, David R. Sweet, Matthew J. Flick, Joseph S. Palumbo, Mei Cheng, Naomi L. Esmon, Charles T. Esmon, Alexander Brill, Denisa D. Wagner, Jay L. Degen, Eric S. Mullins
Journal: Blood
Blood (2016) 128 (5): 721–731.
https://doi.org/10.1182/blood-2015-11-680280
Published: 2016
Includes: Multimedia, Supplemental data
Journal Articles

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

Fabrizio Semeraro, Concetta T. Ammollo, James H. Morrissey, George L. Dale, Paul Friese, Naomi L. Esmon, Charles T. Esmon
Journal: Blood
Blood (2011) 118 (7): 1952–1961.
https://doi.org/10.1182/blood-2011-03-343061
Published: 2011
Journal Articles

The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A

Matthew J. Flick, Anil K. Chauhan, Malinda Frederick, Kathryn E. Talmage, Keith W. Kombrinck, Whitney Miller, Eric S. Mullins, Joseph S. Palumbo, Xunzhen Zheng, Naomi L. Esmon, Charles T. Esmon, Sherry Thornton, Ann Becker, Leslie A. Pelc, Enrico Di Cera, Denisa D. Wagner, Jay L. Degen
Journal: Blood
Blood (2011) 117 (23): 6326–6337.
https://doi.org/10.1182/blood-2010-08-304915
Published: 2011
Journal Articles

Function of Beta2-GPI in Inhibiting the Oxidized Phospholipids Dependent APC Activity by Antiphospholipid IgG from APS Patients.

Yanqing Hu, PhD, Charles T. Esmon, PhD, Naomi L. Esmon, PhD
Journal: Blood
Blood (2006) 108 (11): 1612.
https://doi.org/10.1182/blood.V108.11.1612.1612
Published: 2006
Journal Articles

Effects of membrane and soluble EPCR on the hemostatic balance and endotoxemia in mice

Xunzhen Zheng, Weihong Li, Jian-Ming Gu, Dongfeng Qu, Gary L. Ferrell, Naomi L. Esmon, Charles T. Esmon
Journal: Blood
Blood (2006) 109 (3): 1003–1009.
https://doi.org/10.1182/blood-2006-06-032086
Published: 2006
Journal Articles

Extraembryonic expression of EPCR is essential for embryonic viability

Weihong Li, Xunzhen Zheng, Jian-Ming Gu, Gary L. Ferrell, Mingming Brady, Naomi L. Esmon, Charles T. Esmon
Journal: Blood
Blood (2005) 106 (8): 2716–2722.
https://doi.org/10.1182/blood-2005-01-0406
Published: 2005
Journal Articles

Inhibition of APC anticoagulant activity on oxidized phospholipid by anti–β 2 -glycoprotein I monoclonal antibodies

Omid Safa, Charles T. Esmon, Naomi L. Esmon
Journal: Blood
Blood (2005) 106 (5): 1629–1635.
https://doi.org/10.1182/blood-2005-01-0404
Published: 2005
Journal Articles

Inhibition of Activated Protein C Anticoagulant Activity by Prothrombin

Mikhail D. Smirnov, Omid Safa, Naomi L. Esmon, Charles T. Esmon
Journal: Blood
Blood (1999) 94 (11): 3839–3846.
https://doi.org/10.1182/blood.V94.11.3839
Published: 1999