Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 152

Sort by

Sort Order Select

Journal Articles

Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers

Blood (2020) 136 (11): 1303–1316.

https://doi.org/10.1182/blood.2019001808

Published: 2020

Includes: Supplemental data

Journal Articles

Pharmacologic Activation of Aldehyde Metabolism to Protect Hematopoietic Stem Cells (HSC) in Murine Models of Fanconi Anemia (FA)

Jennifer Tsai, MD, Kelsey R. Logas, MS, Lauren D. Van Wassenhove, PhD, Beruh Dejene, BS, Che-Hong Chen, PhD, Daria Mochly-Rosen, PhD, Kenneth I. Weinberg, MD

Blood (2019) 134 (Supplement_1): 105.

https://doi.org/10.1182/blood-2019-124439

Published: 2019

Journal Articles

Repurposing Clofazimine As a Novel Drug for the Treatment of PI-Resistant Stem Cell-like Subclones in Myeloma

Harish Kumar, PhD, Ujjal Kumar Mukherjee, PhD, Suman Mazumder, PhD, Sabyasachi Sanyal, PhD, Brian G. Van Ness, PhD, Amit Kumar Mitra, PhD MSc, BSc

Blood (2019) 134 (Supplement_1): 4418.

https://doi.org/10.1182/blood-2019-131596

Published: 2019

Journal Articles

Lineage Tracing in Chronic Lymphocytic Leukemia Reveals Clones with Stable Gene Expression States That Differentially Respond to Therapy

Catherine Gutierrez, Aziz Al'Khafaji, B.S., Eric Brenner, B.S., Russell Durrett, B.S., M.S., Kaitlyn Johnson, B.S., M.S., Wandi Zhang, MD, Shuqiang Li, PhD, Kenneth J. Livak, PhD, Donna S Neuberg, ScD, Amy Brock, PhD, Catherine J. Wu, MD

Blood (2019) 134 (Supplement_1): 1229.

https://doi.org/10.1182/blood-2019-129303

Published: 2019

Journal Articles

Dual Targeting of ALDH1 and ALDH3: A Promising Therapeutic Approach in Acute Myeloid Leukemia

Mileidys Perez-Alea, Sr., PhD, Julien Colle, Jr., MD, Muhube Yazir, Jr., MSc, Céline Baier, Jr., PhD, Yasmine Labiad, PhD, Isabelle Arnoux, Sr., Hematologist, Geoffroy Venton, Jr., PhD MD, Guillaume Guillaume, MSc, Ismail Ceylan, MSc, Regis T. Costello, Sr., MD PhD

Blood (2019) 134 (Supplement_1): 3364.

https://doi.org/10.1182/blood-2019-126484

Published: 2019

Journal Articles

The Novel Small Molecule Inhibitor KS99 Targets AML and Inhibits Stemness Markers STAT3 and ALDH

Charyguly Annageldiyev, Krishne Gowda, Dhimant Desai, Viola Devine, Daniel Brosius, Chandrika Gowda, MBBS, Sinisa Dovat, MD PhD, Shantu Amin, David F. Claxton, MD, Arati Sharma, PhD

Blood (2018) 132 (Supplement 1): 1440.

https://doi.org/10.1182/blood-2018-99-117376

Published: 2018

Journal Articles

Sequential Treatment with Rigosertib Followed By Azacitidine Maximizes the Effects on the Interferon Signaling Pathway in Hematopoietic Cells in Myelodysplastic Syndrome (MDS)

Richa Rai, PhD, Stella Melana, PhD, Shyamala C. Navada, MD, Rosalie Odchimar-Reissig, RN, Erin P. Demakos, RN, E. Premkumar Reddy, PhD, Lewis R. Silverman, MD

Blood (2018) 132 (Supplement 1): 5500.

https://doi.org/10.1182/blood-2018-99-119266

Published: 2018

Journal Articles

Aldehyde Dehydrogenase 2 ( ALDH2 ) Expression Predicts a Poor Prognosis in Acute Myeloid Leukemia

Linus Angenendt, Eike Bormann, Jan-Henrik Mikesch, Tobias Herold, Klaus H. Metzeler, MD, Stefan K. Bohlander, MD, Dennis Görlich, Maria Francisca Arteaga, Bernhard J. Wörmann, Georg Lenz, Wolfgang Hiddemann, Karsten Spiekermann, Utz Krug, Christina Sauerland, Wolfgang E. Berdel, Christoph Schliemann

Blood (2017) 130 (Supplement 1): 1386.

https://doi.org/10.1182/blood.V130.Suppl_1.1386.1386

Published: 2017

Journal Articles

Bortezomib-Activated Macrophages Contribute to Multiple Myeloma Progression Via Cancer Stem Cell Enrichment

Ofrat Beyar Katz, MD, Ksenia Magidey Klein, M.Sc, Michael Timaner, PhD, Ziv Raviv, PhD, Noam Benyamini, MD, Benjamin Brenner, MD, Yuval Shaked, PhD

Blood (2017) 130 (Supplement 1): 2269.

https://doi.org/10.1182/blood.V130.Suppl_1.2269.2269

Published: 2017

Journal Articles

Bone Marrow Stromal Cells Induce ALDH+ Stem Cell Phenotype and Chemotherapy Resistance in AML Cells through TGF-β1 Mediated Signaling: Reversal By TGFβ Inhibitor Galunisertib

Ximin Zhou, Bin Yuan, Yuanqing Yan, Khoa Nguyen, Vivian Ruvolo, PhD, Hong Mu, MD PhD, Teresa McQueen, MS, Elizabeth J Shpall, MD, Kim-Ann Do, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD, Venkata Lokesh Battula, PhD

Blood (2017) 130 (Supplement 1): 1163.

https://doi.org/10.1182/blood.V130.Suppl_1.1163.1163

Published: 2017

Journal Articles

The Exhaustion of Adult Hematopoietic Stem Cells in Ex Vivo Cultures Can Be Overcome by a Histone Deacetylase Inhibitor

Eran Zimran, MD, Luena Papa, PhD, Mansour Djedaini, BS, Ronald Hoffman, MD

Blood (2017) 130 (Supplement 1): 655.

https://doi.org/10.1182/blood.V130.Suppl_1.655.655

Published: 2017

Journal Articles

Effects of Rigosertib (RIGO) Alone or in Combination with Azacitidine or Vorinostat on Epigenetic Reprogramming of CD34+ Cells in the Myelodysplastic Syndrome

Lewis R Silverman, MD, Pratima Chaurasia, PhD, Stella Melana, PhD, Rosalie Odchimar-Reissig, RN, Erin P. Demakos, BA, BSN, MSN, RN, Shyamala C. Navada, MD, E. Premkumar Reddy, PhD BSc, MSc

Blood (2017) 130 (Supplement 1): 4235.

https://doi.org/10.1182/blood.V130.Suppl_1.4235.4235

Published: 2017

Journal Articles

Imetelstat, a Telomerase Inhibitor, Is Capable of Depleting Myelofibrosis Hematopoietic Stem Cells and Progenitor Cells

Cing Siang Hu, Jiajing Qiu, Fei Huang, PhD, Ronald Hoffman, MD, Xiaoli Wang, PhD

Blood (2017) 130 (Supplement 1): 1654.

https://doi.org/10.1182/blood.V130.Suppl_1.1654.1654

Published: 2017

Journal Articles

A Novel Approach to Identify a Putative Leukemia Stem Cell Population in Acute Lymphocytic Leukemia (ALL) and Distinguish Philadelphia Chromosome-Positive ALL from Lymphoid Blast Crisis Chronic Myeloid Leukemia

Jonathan M. Gerber, MD, Lawrence J. Druhan, PhD, David Foureau, PhD, Elizabeth Jandrisevits, Amanda Lance, BS, Andrea E. Price, BS, Virginia Thurston, PhD, Jing Ai, MD PhD, Michael R. Grunwald, MD, Edward H. Lipford, MD, Belinda R. Avalos, MD

Blood (2016) 128 (22): 2912.

https://doi.org/10.1182/blood.V128.22.2912.2912

Published: 2016

Journal Articles

Multiple Myeloma Cancer Stem Cells: Immunophenotypic and Functional Characterization, Gene Expression Profiling and Therapeutic Targets

Mariana Bleker de Oliveira, BSc, Paola Marino Dantonio, BSc, Veruska Lia Fook Alves, PhD, Rodrigo Carlini Fernando, BSc, Daniela Teixeira, MSc, Alexandre Basso, PhD, Mihoko Yamamoto, MD PhD, Gisele W. B. Colleoni, MD PhD

Blood (2016) 128 (22): 4434.

https://doi.org/10.1182/blood.V128.22.4434.4434

Published: 2016

Journal Articles

Molecular Signature of Dormancy in CD34+CD38- Acute Myeloid Leukaemia Cells

Mazin Gh Al-Asadi, MD, Marcos Castellanos, PhD, Sean T May, Professor, Nigel H Russell, MD, Claire H Seedhouse, PhD, Monica Pallis, PhD

Blood (2016) 128 (22): 1660.

https://doi.org/10.1182/blood.V128.22.1660.1660

Published: 2016

Journal Articles

Expression of DDIT4 Is Correlated with NOTCH1 and High Molecular Risk in Acute Myeloid Leukemias

Joseph A Pinto, Leny Bravo, Luis A. Chirinos, Carlos E Vigil

Blood (2016) 128 (22): 5254.

https://doi.org/10.1182/blood.V128.22.5254.5254

Published: 2016

Journal Articles

Natural Killer Cell Reconstitution after Haploidentical Hematopoietic Stem Cell Transplantation with Post-Transplant Cyclophosphamide: Elimination of Donor-Derived Mature Alloreactive NK Cells, but Favorable Conditions for Adoptive Immunotherapy

Antonio Russo, Giacomo Oliveira, PhD, Sofia Berglund, MD PhD, Raffaella Greco, MD, Valentina Gambacorta, MSc, Nicoletta Cieri, MD PhD, Cristina Toffalori, PhD, Laura Zito, MSc, Simona Piemontese, MD, Mara Morelli, MD, Fabio Giglio, MD, Andrea Angelo Assanelli, MD, Maria Teresa Lupo Stanghellini, MD, Chiara Bonini, MD, Jacopo Peccatori, MD, Leo Luznik, MD, Fabio Ciceri, MD, Luca Vago, MD PhD

Blood (2016) 128 (22): 4567.

https://doi.org/10.1182/blood.V128.22.4567.4567

Published: 2016

Journal Articles

Aldehyde Dehydrogenase Activity in the Leukemic Stem Cell Compartment Uncovers Opposing Methylation Patterns of Leukemia Stem Cells in AML

Lauren Suarez, Tingting Qin, PhD, Kristen Meldi, PhD, Manjusha Thakar, Sarah Sakoian, Gabriel Ghiaur, MD PhD, Jonathan M. Gerber, MD, Hetty E. Carraway, MD MBA, Maria E Figueroa, MD, Steven D. Gore, MD

Blood (2016) 128 (22): 3925.

https://doi.org/10.1182/blood.V128.22.3925.3925

Published: 2016

Journal Articles

Development and validation of a rapid, aldehyde dehydrogenase bright–based cord blood potency assay

Kevin Shoulars, Pamela Noldner, Jesse D. Troy, Lynn Cheatham, Amanda Parrish, Kristin Page, Tracy Gentry, Andrew E. Balber, Joanne Kurtzberg

Blood (2016) 127 (19): 2346–2354.

https://doi.org/10.1182/blood-2015-08-666990

Published: 2016

NARROW

Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers

Pharmacologic Activation of Aldehyde Metabolism to Protect Hematopoietic Stem Cells (HSC) in Murine Models of Fanconi Anemia (FA)

Repurposing Clofazimine As a Novel Drug for the Treatment of PI-Resistant Stem Cell-like Subclones in Myeloma

Lineage Tracing in Chronic Lymphocytic Leukemia Reveals Clones with Stable Gene Expression States That Differentially Respond to Therapy

Dual Targeting of ALDH1 and ALDH3: A Promising Therapeutic Approach in Acute Myeloid Leukemia

The Novel Small Molecule Inhibitor KS99 Targets AML and Inhibits Stemness Markers STAT3 and ALDH

Sequential Treatment with Rigosertib Followed By Azacitidine Maximizes the Effects on the Interferon Signaling Pathway in Hematopoietic Cells in Myelodysplastic Syndrome (MDS)

Aldehyde Dehydrogenase 2 ( ALDH2 ) Expression Predicts a Poor Prognosis in Acute Myeloid Leukemia

Bortezomib-Activated Macrophages Contribute to Multiple Myeloma Progression Via Cancer Stem Cell Enrichment

Bone Marrow Stromal Cells Induce ALDH+ Stem Cell Phenotype and Chemotherapy Resistance in AML Cells through TGF-β1 Mediated Signaling: Reversal By TGFβ Inhibitor Galunisertib

The Exhaustion of Adult Hematopoietic Stem Cells in Ex Vivo Cultures Can Be Overcome by a Histone Deacetylase Inhibitor

Effects of Rigosertib (RIGO) Alone or in Combination with Azacitidine or Vorinostat on Epigenetic Reprogramming of CD34+ Cells in the Myelodysplastic Syndrome

Imetelstat, a Telomerase Inhibitor, Is Capable of Depleting Myelofibrosis Hematopoietic Stem Cells and Progenitor Cells

A Novel Approach to Identify a Putative Leukemia Stem Cell Population in Acute Lymphocytic Leukemia (ALL) and Distinguish Philadelphia Chromosome-Positive ALL from Lymphoid Blast Crisis Chronic Myeloid Leukemia

Multiple Myeloma Cancer Stem Cells: Immunophenotypic and Functional Characterization, Gene Expression Profiling and Therapeutic Targets

Molecular Signature of Dormancy in CD34+CD38- Acute Myeloid Leukaemia Cells

Expression of DDIT4 Is Correlated with NOTCH1 and High Molecular Risk in Acute Myeloid Leukemias

Natural Killer Cell Reconstitution after Haploidentical Hematopoietic Stem Cell Transplantation with Post-Transplant Cyclophosphamide: Elimination of Donor-Derived Mature Alloreactive NK Cells, but Favorable Conditions for Adoptive Immunotherapy

Aldehyde Dehydrogenase Activity in the Leukemic Stem Cell Compartment Uncovers Opposing Methylation Patterns of Leukemia Stem Cells in AML

Development and validation of a rapid, aldehyde dehydrogenase bright–based cord blood potency assay

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only