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Journal Articles

AMP-activated protein kinase links acetyl-CoA homeostasis to BRD4 recruitment in acute myeloid leukemia

Yajian Jiang, Tianyuan Hu, Tao Wang, Xiangguo Shi, Ayumi Kitano, Kenneth Eagle, Kevin A. Hoegenauer, Marina Y. Konopleva, Charles Y. Lin, Nicolas L. Young, Daisuke Nakada

Blood (2019) 134 (24): 2183–2194.

https://doi.org/10.1182/blood.2019001076

Published: 2019

Includes: Supplemental data

Journal Articles

Identify AMPK-Mediated Autophagy and Oxphos As a Novel Metabolic Vulnerability for Targeted Therapy in Mantle Cell Lymphoma

Yixin Yao, PhD, Yang Liu, MD, Hui Zhang, Angela Leeming, Joseph Mitchell McIntosh, Preetesh Jain, MBBS,MDDM,PhD, Liang Zhang, MD PhD, Krystle Nomie, PhD, Michael L. Wang, MD

Blood (2019) 134 (Supplement_1): 1506.

https://doi.org/10.1182/blood-2019-126738

Published: 2019

Journal Articles

Ibrutinib in Combination with Venetoclax Decreases Mitochondrial Bioenergetics through the Impaired BTK, AKT and AMPK/SIRT/PGC-1α Signaling Pathway in CLL

Subir Roy Chowdhury, MD PhD, Amandeep Singh, MSc, Edwin Nguyen, Aaron Marshall, PhD, James B. Johnston, MD, Spencer Bruce Gibson, PhD, Versha Banerji, MD

Blood (2019) 134 (Supplement_1): 1282.

https://doi.org/10.1182/blood-2019-127562

Published: 2019

Journal Articles

MCL-1 and PKA/AMPK Axis Fuel Venetoclax Resistance in Lymphoid Cancers

Blood (2019) 134 (Supplement_1): 1284.

https://doi.org/10.1182/blood-2019-131336

Published: 2019

Journal Articles

Maternal Erythrocyte ENT1-Mediated AMPK Activation and Oxygen Delivery: A Missing Component Counteracting Placental Hypoxia, Dysfunction, and Fetal Growth Restriction

Seisuke Sayama, MD PhD, Anren Song, PhD, Yang Xia, MD PhD

Blood (2019) 134 (Supplement_1): 341.

https://doi.org/10.1182/blood-2019-123053

Published: 2019

Journal Articles

Glia Maturation Factor-γ Regulates Autophagy in Murine Macrophages

Wulin Aerbajinai, MD PhD, Jianqiong Zhu, MD, Chutima Kumkhaek, PhD, Kyung Chin, Griffin Rodgers, MD

Blood (2019) 134 (Supplement_1): 2318.

https://doi.org/10.1182/blood-2019-130318

Published: 2019

Journal Articles

The Role of Adenosine Monophosphate Activated Protein Kinase Alpha 1 (AMPK) in Gamma-Globin Regulation

Alicia Chang, MD, Yankai Zhang, PhD, Nelda Itzep, MD, Vivien A Sheehan, MD PhD

Blood (2018) 132 (Supplement 1): 413.

https://doi.org/10.1182/blood-2018-99-117092

Published: 2018

Journal Articles

Bone Marrow Hematopoietic Connexin 43 Is Required for Mitotransfer and AMPK Dependent Mesenchymal Microenvironment Regeneration after Irradiation

Abhishek K Singh, PhD, Karin Golan, PhD, Mark J Althoff, BS, Ekaterina Petrovich-Kopitman, Ashley M Wellendorf, B.S., Fatima Mohmoud, B.S., Mayla Bertagna, MSc, Daniel Gonzalez-Nieto, PhD, Luis C Barrio, MD PhD, Tsvee Lapidot, PhD, Jose A Cancelas, MD PhD

Blood (2018) 132 (Supplement 1): 872.

https://doi.org/10.1182/blood-2018-99-118292

Published: 2018

Journal Articles

AMPK Regulates the Expression of the Fe-S Cluster Assembly Enzyme (ISCU) and ALAS2, Modulating Cellular Iron Metabolism and Increasing Hemoglobin Synthesis

Ping La, Silvia Pires Lourenco, MSc, Laura Breda, PhD, Stefano Rivella

Blood (2018) 132 (Supplement 1): 851.

https://doi.org/10.1182/blood-2018-99-112175

Published: 2018

Journal Articles

The Role of AMPK in Chemotherapy Response in AML

Lais P Ghiraldeli, MS, Rebecca G. Anderson, B.S., Kristin M. Pladna, M.S., Timothy Pardee, MD PhD

Blood (2018) 132 (Supplement 1): 2633.

https://doi.org/10.1182/blood-2018-99-119288

Published: 2018

Journal Articles

Metformin Restores AMPK Alpha-Mediated Autophagy and Prevents Carfilzomib-Induced Cardiotoxicity In Vivo

Georgios Kremastiotis, Panagiotis Efentakis, Aimilia Varela, Constantinos H. Davos, Maria Tsoumani, Georgios Agrogiannis, Anastasia Konstantinidou, Eleni-Dimitra Papanagnou, Ioannis P. Trougakos, Eftathios Kastritis, Zoi Kanaki, Efstathios K. Iliodromitis, Apostolos Klinakis, Meletios A Dimopoulos, MD, Ioanna Andreadou, Evangelos Terpos, MD PhD

Blood (2018) 132 (Supplement 1): 3214.

https://doi.org/10.1182/blood-2018-99-112351

Published: 2018

Journal Articles

Venetoclax in Combination with NAMPT Inhibitors Decreases Mitochondrial Bioenergetics through the Impaired AMPK/SIRT/PGC1α Signaling Pathway in CLL

Subir Roy Chowdhury, MD PhD, Saleh Ryan, BSc, Cheryl Peltier, BSc, Mandy Squires, CCRP, HIT, Donna Hewitt, R.N., Paul Fernyhough, PhD, Spencer Bruce Gibson, PhD, Versha Banerji, MD

Blood (2018) 132 (Supplement 1): 1368.

https://doi.org/10.1182/blood-2018-99-112210

Published: 2018

Journal Articles

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation

Blood (2018) 132 (11): 1180–1192.

https://doi.org/10.1182/blood-2018-02-831503

Published: 2018

Includes: Supplemental data

Journal Articles

Control of Hematopoietic Stem Cell Function through Epigenetic Regulation of Energy Metabolism and Genome Integrity

Zhenhua Yang, PhD, Hao Jiang

Blood (2017) 130 (Supplement 1): 772.

https://doi.org/10.1182/blood.V130.Suppl_1.772.772

Published: 2017

Journal Articles

A Novel Role for AMP-Activated Protein Kinase (AMPK) in Controlling T Cell Sensitivity to IL-6

Kevin Beezhold, PhD, Rebecca Brown, Craig Byersdorfer, MD

Blood (2017) 130 (Supplement 1): 1890.

https://doi.org/10.1182/blood.V130.Suppl_1.1890.1890

Published: 2017

Journal Articles

Stat5 Feedback Control Switches MYC- and BCL6-Dependent Cell Fates in Normal and Transformed B Cells

Zhengshan Chen, MDPhD, Lai N Chan, Huimin Geng, PhD, Merja Heinäniemi, PhD, Olli Lohi, MD PhD, Cheryl L. Willman, MD, Markus Muschen, MDPhD

Blood (2017) 130 (Supplement 1): 1440.

https://doi.org/10.1182/blood.V130.Suppl_1.1440.1440

Published: 2017

Journal Articles

AMPK Links Metabolic Regulation to Epigenome Modification in Leukemia-Initiating-Cell

Yajian Jiang, MBBS, Daisuke Nakada, PhD, Ayumi Kitano

Blood (2017) 130 (Supplement 1): 2488.

https://doi.org/10.1182/blood.V130.Suppl_1.2488.2488

Published: 2017

Journal Articles

Novel Oxidative Phosphorylation Inhibitor IACS-010759 Induces AMPK-Dependent Apoptosis of AML Cells

Haeun Yang, Yoko Tabe, MD PhD, Kazumasa Sekihara, PhD, Kaori Saito, Helen Ma, MS, Vivian Ruvolo, PhD, Junichi Imoto, Kazuho Ikeo, PhD, Kaoru Mogushi, PhD, Masaki Hosoya, Yoshihide Hayashizaki, MD PhD, Yasunari Yamanaka, MD PhD, Takashi Miida, MD PhD, Michael Andreeff, MD PhD, Joseph R Marszalek, PhD, Marina Konopleva, MD PhD

Blood (2017) 130 (Supplement 1): 1245.

https://doi.org/10.1182/blood.V130.Suppl_1.1245.1245

Published: 2017

Journal Articles

Alterations in Pathways Regulating Phosphatidil Inositol 3 Phosphate (PI3P) Produce Both Cell Proliferation and Therapy Resistance, and Define a Group of Patients with Poor Prognosis in Acute Myeloid Leukemia (AML)

Blood (2016) 128 (22): 1679.

https://doi.org/10.1182/blood.V128.22.1679.1679

Published: 2016

Journal Articles

Landscape of Somatic Mutations and Gene Expression Changes in Relapsed Infant MLL-Rearranged Acute Lymphoblastic Leukemia

Rumen Kostadinov, PhD, Midhat Farooqi, MD PhD, Byunggil Yoo, MS, Emily Farrow, PhD CGC, Shannon Kelley, Margaret Gibson, Neil Miller, Erin M. Guest, MD, Patrick Brown, MD

Blood (2016) 128 (22): 1735.

https://doi.org/10.1182/blood.V128.22.1735.1735

Published: 2016

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AMP-activated protein kinase links acetyl-CoA homeostasis to BRD4 recruitment in acute myeloid leukemia

Identify AMPK-Mediated Autophagy and Oxphos As a Novel Metabolic Vulnerability for Targeted Therapy in Mantle Cell Lymphoma

Ibrutinib in Combination with Venetoclax Decreases Mitochondrial Bioenergetics through the Impaired BTK, AKT and AMPK/SIRT/PGC-1α Signaling Pathway in CLL

MCL-1 and PKA/AMPK Axis Fuel Venetoclax Resistance in Lymphoid Cancers

Maternal Erythrocyte ENT1-Mediated AMPK Activation and Oxygen Delivery: A Missing Component Counteracting Placental Hypoxia, Dysfunction, and Fetal Growth Restriction

Glia Maturation Factor-γ Regulates Autophagy in Murine Macrophages

The Role of Adenosine Monophosphate Activated Protein Kinase Alpha 1 (AMPK) in Gamma-Globin Regulation

Bone Marrow Hematopoietic Connexin 43 Is Required for Mitotransfer and AMPK Dependent Mesenchymal Microenvironment Regeneration after Irradiation

AMPK Regulates the Expression of the Fe-S Cluster Assembly Enzyme (ISCU) and ALAS2, Modulating Cellular Iron Metabolism and Increasing Hemoglobin Synthesis

The Role of AMPK in Chemotherapy Response in AML

Metformin Restores AMPK Alpha-Mediated Autophagy and Prevents Carfilzomib-Induced Cardiotoxicity In Vivo

Venetoclax in Combination with NAMPT Inhibitors Decreases Mitochondrial Bioenergetics through the Impaired AMPK/SIRT/PGC1α Signaling Pathway in CLL

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation

Control of Hematopoietic Stem Cell Function through Epigenetic Regulation of Energy Metabolism and Genome Integrity

A Novel Role for AMP-Activated Protein Kinase (AMPK) in Controlling T Cell Sensitivity to IL-6

Stat5 Feedback Control Switches MYC- and BCL6-Dependent Cell Fates in Normal and Transformed B Cells

AMPK Links Metabolic Regulation to Epigenome Modification in Leukemia-Initiating-Cell

Novel Oxidative Phosphorylation Inhibitor IACS-010759 Induces AMPK-Dependent Apoptosis of AML Cells

Alterations in Pathways Regulating Phosphatidil Inositol 3 Phosphate (PI3P) Produce Both Cell Proliferation and Therapy Resistance, and Define a Group of Patients with Poor Prognosis in Acute Myeloid Leukemia (AML)

Landscape of Somatic Mutations and Gene Expression Changes in Relapsed Infant MLL-Rearranged Acute Lymphoblastic Leukemia

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