Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 41

Sort by

Sort Order Select

Journal Articles

β 2 -m - a Trigger for NLRP3 Inflammasome Activation within Macrophages Promoting Multiple Myeloma Cell Proliferation

Daniel Hofbauer, Dimitrios Mougiakakos, MD, Maike Büttner-Herold, Frank Neumann, PhD, Jens Nolting, Savita Bisht, Robert Zeiser, MD, Shaima'A Hamarsheh, MSc,BSc, Stefano Ricagno, PhD, Mario Zaiss, Martin Eberhardt, Martin Boettcher, PhD, Katrin Bitterer, Andreas Mackensen, MD, Heiko Bruns, PhD

Blood (2019) 134 (Supplement_1): 2314.

https://doi.org/10.1182/blood-2019-123958

Published: 2019

Journal Articles

Activation of Autophagy in Models of SF3B1 Mutant MDS

Blood (2017) 130 (Supplement 1): 4230.

https://doi.org/10.1182/blood.V130.Suppl_1.4230.4230

Published: 2017

Journal Articles

A Novel Antibody-Toxin Congujate to Treat Mantle Cell Lymphoma

Gulam M Rather, PhD, Siang-Yo Lin, Hongxia Lin, Chen-Yong Lin, Michael D Johnson, Zoltan Szekely, Joseph R Bertino, MD

Blood (2017) 130 (Supplement 1): 5159.

https://doi.org/10.1182/blood.V130.Suppl_1.5159.5159

Published: 2017

Journal Articles

Lysosomal Cell Death and Apoptosis Crosstalk - Synergistic Role in Bcl-2 Inhibitor (ABT-263) Mediated Cell Death in B-Cell Precursor Acute Lymphoblastic Leukemia

Stefanie Enzenmüller, PhD, Qian Sun, PhD, Klaus-Michael Debatin, MD PhD, Lüder-Hinrich Meyer, MD

Blood (2016) 128 (22): 1584.

https://doi.org/10.1182/blood.V128.22.1584.1584

Published: 2016

Journal Articles

Targeting Autophagy in Myelodysplastic Syndromes

Valeria Visconte, PhD, Steffan T. Nawrocki, PhD, Bartlomiej P Przychodzen, MSc, Kevin R. Kelly, MD PhD, Mei Yin, Yvonne Parker, Michael J. Clemente, M.S., John Barnard, PhD, Anjali S. Advani, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Daniel Lindner, Heesun J Rogers, MD PhD, Jaroslaw P Maciejewski, MD PhD FACP, Jennifer S. Carew, PhD

Blood (2016) 128 (22): 4295.

https://doi.org/10.1182/blood.V128.22.4295.4295

Published: 2016

Journal Articles

Activation of Lysosomal Function and Reactive Oxygen Species Play Crucial Roles in SAR650984-Induced Direct Killing of Human Multiple Myeloma Cells with Mutated p53, Which Is Further Augmented By Pomalidomide

Hua Jiang, MDPhD, Chirag Acharya, MD, Gang An Gang An, MDPhD, Xiaoyan Feng, MD, Zhili Song, Guang Yang, PhD, Francisco Adrian, Lugui Qiu, MD, Paul Richardson, MD, Nikhil C. Munshi, MD, Yu-Tzu Tai, PhD, Kenneth C Anderson, MD

Blood (2015) 126 (23): 4253.

https://doi.org/10.1182/blood.V126.23.4253.4253

Published: 2015

Journal Articles

Elevated Basal Autophagy in SF3B1 Mutated Myelodysplastic Syndromes: Relationship with Survival Outcomes and Therapeutic Implications

Valeria Visconte, PhD, Kevin R. Kelly, MD PhD, Steffan T. Nawrocki, PhD, Yingchun Han, MD, Hetty E. Carraway, MD MBA, Anjali S. Advani, MD, Jaroslaw P. Maciejewski, MD PhD, Heesun J Rogers, MD PhD, Mikkael A. Sekeres, MD MS, Jennifer S. Carew, PhD

Blood (2015) 126 (23): 1647.

https://doi.org/10.1182/blood.V126.23.1647.1647

Published: 2015

Journal Articles

Cathepsin-Cleavable BIM BH3 Peptide Amphiphiles Are Potent Inducers of Cellular Apoptosis

Joseph Bellairs, Ravand Samaeekia, Handan Acar, PhD, Matthew Tirrell, PhD, James LaBelle, MD PhD

Blood (2015) 126 (23): 4438.

https://doi.org/10.1182/blood.V126.23.4438.4438

Published: 2015

Journal Articles

Cathepsin B Mediated Lysosomal Degradation in Macrophages Controls the Pharmacokinetics of the Therapeutic Protein Asparaginase

Laurens T Van Der Meer, PhD, Samantha YA Terry, PhD, Dorette van Ingen Schenau, MSc, Kiki Andree, MSc, Gerben M Franssen, BSc, Debbie Roeleveld, MSc, Bart Metselaar, PhD, Thomas Reinheckel, PhD, Peter M Hoogerbrugge, MD PhD, Otto C Boerman, PhD, Frank N van Leeuwen, PhD

Blood (2015) 126 (23): 3768.

https://doi.org/10.1182/blood.V126.23.3768.3768

Published: 2015

Journal Articles

Cytogenetic Analysis of Multiple Myeloma Identifies Cytogenetic Alterations Implicated in Disease Complexity and Progression

Erik Wendlandt, PhD, Guido J. Tricot, MD, PhD, Benjamin Darbro, Fenghuang Zhan, MD PhD

Blood (2014) 124 (21): 3360.

https://doi.org/10.1182/blood.V124.21.3360.3360

Published: 2014

Journal Articles

Cellular Labile Iron Activates NLRP3 Inflammasome

Kyohei Nakamura, MDPhD, Tohru Fujiwara, MD PhD, Tomonori Ishii, MDPhD, Hideo Harigae, MD PhD, Kouetsu Ogasawara, PhD

Blood (2014) 124 (21): 2723.

https://doi.org/10.1182/blood.V124.21.2723.2723

Published: 2014

Journal Articles

A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics

Laurens T. van der Meer, Esmé Waanders, Marloes Levers, Hanka Venselaar, Debbie Roeleveld, Joachim Boos, Claudia Lanvers, Roger J. Brüggemann, Roland P. Kuiper, Peter M. Hoogerbrugge, Frank N. van Leeuwen, D. Maroeska te Loo

Blood (2014) 124 (19): 3027–3029.

https://doi.org/10.1182/blood-2014-06-582627

Published: 2014

Includes: Supplemental data

Journal Articles

Evaluation Of Acadesine, a Drug Stimulating Cell Autophagy, In Azacitidine(AZA)-Resistant Myelodysplastic Syndromes (MDS)

Thomas Cluzeau, MD, PhD, Guillaume Robert, PhD, Jean Michel Karsenti, MD, Frederic Luciano, PhD, Nicolas Mounier, MD, PhD, Jill Patrice Cassuto, MD, PhD, Lionel Ades, Sophie Raynaud, MD, PhD, Pierre Fenaux, MD, PhD, Patrick Auberger, PhD

Blood (2013) 122 (21): 1568.

https://doi.org/10.1182/blood.V122.21.1568.1568

Published: 2013

Journal Articles

Purified CD4 T Lymphocyte Infusion Can Result in Graft-Versus-Leukemia Reactivity without Gvhd by Recognition of Broadly Expressed Minor Histocompatibility Antigens in HLA Class-II

P. van Balen, MD, C.A.M. van Bergen, I. Jedema, PhD, S.A.P. van Luxemburg-Heijs, J.C. Harskamp, H.M. van Egmond, S.A.J. Veld, M. Griffioen, PhD, W.A.F. Marijt, MD, PhD, C.J.M. Halkes, MD, PhD, J.H.F. Falkenburg, MD, PhD

Blood (2012) 120 (21): 4116.

https://doi.org/10.1182/blood.V120.21.4116.4116

Published: 2012

Journal Articles

The Valproic Acid-Fludarabine Combination Induces a Synergistic Response in Chronic Lymphocytic Leukemia Via a Mechanism Involving the Lysosomal Protease Cathepsin B.

Ju-Yoon Yoon, David Szwajcer, MD, FRCPC, Ganchimeg Ishdorj, PhD, Pat Benjaminson, RN, CON(C), James B Johnston, MD, Spencer B Gibson, PhD

Blood (2012) 120 (21): 2892.

https://doi.org/10.1182/blood.V120.21.2892.2892

Published: 2012

Journal Articles

Erythropoietin-Directed Erythropoiesis Depends Upon Serpin Inhibition of Erythroblast Lysosomal Cathepsins

Don M. Wojchowski, PhD, Arvind Dev, PhD, Susan M Byrne, PhD, Rakesh Verma, Ph.D, Philip G Ashton-Rickardt, PhD

Blood (2012) 120 (21): 981.

https://doi.org/10.1182/blood.V120.21.981.981

Published: 2012

Journal Articles

A Germline Mutation in Cathepsin B in a Child with ALL Points towards a Key Role for This Enzyme in L-Asparaginase Pharmacokinetics.

Laurens T. van der Meer, PhD, Esmé Waanders, PhD, Marloes Levers, BSc, Hanka Venselaar, MSc, Debbie Roeleveld, BSc, Joachim Boos, MD, PhD, Claudia Lanvers-Kaminsky, PhD, Roland P. Kuiper, PhD, Peter M. Hoogerbrugge, MD, PhD, Frank N. van Leeuwen, PhD, D. Maroeska W.M. te Loo, MD, PhD

Blood (2012) 120 (21): 2458.

https://doi.org/10.1182/blood.V120.21.2458.2458

Published: 2012

Journal Articles

Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide

Dennis J. Goussetis, Elias Gounaris, Edward J. Wu, Eliza Vakana, Bhumika Sharma, Matthew Bogyo, Jessica K. Altman, Leonidas C. Platanias

Blood (2012) 120 (17): 3555–3562.

https://doi.org/10.1182/blood-2012-01-402578

Published: 2012

Includes: Supplemental data

Journal Articles

Fcμ-Receptor (FcμR; TOSO/ FAIM3 ) Mediated Internalization of Antibody-Drug Conjugates: A Novel Approach to Selectively Target Chronic Lymphocytic Leukemia Cells

Berengere Vire, Ph.D., Alexandre David, Ph.D., Joshua D Thomas, Ph.D., Terrence R Burke, Jr., Ph.D., Christoph Rader, Ph.D., Adrian Wiestner, MD, PhD

Blood (2011) 118 (21): 734.

https://doi.org/10.1182/blood.V118.21.734.734

Published: 2011

Journal Articles

Abrogation of Niche Signals Discovered New Genes Regulating Homing, Expansion and homeostasis of Multiple Myeloma Cells

Yossi Cohen, MD, BsC, Osnat Garach-Jehoshua, PhD, Bar-Chaim Adina, PhD, Abraham Kornberg, MD

Blood (2011) 118 (21): 5080.

https://doi.org/10.1182/blood.V118.21.5080.5080

Published: 2011

NARROW

β 2 -m - a Trigger for NLRP3 Inflammasome Activation within Macrophages Promoting Multiple Myeloma Cell Proliferation

Activation of Autophagy in Models of SF3B1 Mutant MDS

A Novel Antibody-Toxin Congujate to Treat Mantle Cell Lymphoma

Lysosomal Cell Death and Apoptosis Crosstalk - Synergistic Role in Bcl-2 Inhibitor (ABT-263) Mediated Cell Death in B-Cell Precursor Acute Lymphoblastic Leukemia

Targeting Autophagy in Myelodysplastic Syndromes

Activation of Lysosomal Function and Reactive Oxygen Species Play Crucial Roles in SAR650984-Induced Direct Killing of Human Multiple Myeloma Cells with Mutated p53, Which Is Further Augmented By Pomalidomide

Elevated Basal Autophagy in SF3B1 Mutated Myelodysplastic Syndromes: Relationship with Survival Outcomes and Therapeutic Implications

Cathepsin-Cleavable BIM BH3 Peptide Amphiphiles Are Potent Inducers of Cellular Apoptosis

Cathepsin B Mediated Lysosomal Degradation in Macrophages Controls the Pharmacokinetics of the Therapeutic Protein Asparaginase

Cytogenetic Analysis of Multiple Myeloma Identifies Cytogenetic Alterations Implicated in Disease Complexity and Progression

Cellular Labile Iron Activates NLRP3 Inflammasome

A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics

Evaluation Of Acadesine, a Drug Stimulating Cell Autophagy, In Azacitidine(AZA)-Resistant Myelodysplastic Syndromes (MDS)

Purified CD4 T Lymphocyte Infusion Can Result in Graft-Versus-Leukemia Reactivity without Gvhd by Recognition of Broadly Expressed Minor Histocompatibility Antigens in HLA Class-II

The Valproic Acid-Fludarabine Combination Induces a Synergistic Response in Chronic Lymphocytic Leukemia Via a Mechanism Involving the Lysosomal Protease Cathepsin B.

Erythropoietin-Directed Erythropoiesis Depends Upon Serpin Inhibition of Erythroblast Lysosomal Cathepsins

A Germline Mutation in Cathepsin B in a Child with ALL Points towards a Key Role for This Enzyme in L-Asparaginase Pharmacokinetics.

Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide

Fcμ-Receptor (FcμR; TOSO/ FAIM3 ) Mediated Internalization of Antibody-Drug Conjugates: A Novel Approach to Selectively Target Chronic Lymphocytic Leukemia Cells

Abrogation of Niche Signals Discovered New Genes Regulating Homing, Expansion and homeostasis of Multiple Myeloma Cells

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only