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Journal Articles

Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells

Harold K. Elias, MD, Christina Spevak, PhD, Lavanya Kannan, PhD, Mohamed A.E. Ali, MD PhD, Gaelle H Martin, PhD, Shanmugapriya Selvaraj, MS, William S Eng, Guangjie Zhao, BS, Amanda Ernlund, PhD, Vinagolu Rajasekhar, PhD, Carolien M Woolthuis, MD PhD, Robert J Schneider, PhD, Christopher Y. Park, MD PhD

Blood (2019) 134 (Supplement_1): 1180.

https://doi.org/10.1182/blood-2019-131333

Published: 2019

Journal Articles

Src-like Adaptor Protein Promotes the CD103 + dendritic Cell Homeostasis in the Lung

Namit Sharma, Pan Zhongda, Tracy Lauren Smith, Savar Kaul, Emilie Ernoult, Jane McGlade

Blood (2016) 128 (22): 1339.

https://doi.org/10.1182/blood.V128.22.1339.1339

Published: 2016

Journal Articles

Alteration of Chromatin Modifiers and Misregulation of Transcription Factors Define the Genomic Profile of Infant AML

Rhonda E. Ries, MA, Hamid Bolouri, PhD, Jason E Farrar, MD, Emilia L. Lim, PhD, Timothy Junius Triche, Jr., PhD, Katherine Tarlock, MD, Jaime Guidry Auvil, PhD, Betsy A. Hirsch, PhD, Susana C. Raimondi, PhD, Yussanne Ma, PhD, Marco A. Marra, PhD, Richard Aplenc, MD PhD, Erin M. Guest, MD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Soheil Meshinchi, MD PhD

Blood (2016) 128 (22): 774.

https://doi.org/10.1182/blood.V128.22.774.774

Published: 2016

Journal Articles

C-Cbl Regulates c-Mpl Receptor Trafficking and Its Internalization

Sebastian Jonas Saur, MD, Melanie Märklin, PhD, Manuela Ganser, Kyle Hoehn, James E David, PhD, Oliver Borst, MD, Lothar Kanz, MD, Hans-Georg Kopp, MD, Martin R Mueller, MD PhD

Blood (2015) 126 (23): 2388.

https://doi.org/10.1182/blood.V126.23.2388.2388

Published: 2015

Journal Articles

Cbl Y371H Transgene Combined with Hematopoietic Deletion of the Endogenous c-Cbl Gene Results in GM-CSF Hypersensitivity and Leukocytosis

Kenneth Lieuw, MD PhD, Jayasree Krishnamurthy, MS, Mignon L. Loh, MD

Blood (2015) 126 (23): 3672.

https://doi.org/10.1182/blood.V126.23.3672.3672

Published: 2015

Journal Articles

Comprehensive Genomic and Transcript Profiling of CBL Gene in Childhood AML: A Report from Children's Oncology Group Studies AAML03P1, AAML0531 and COG/NCI Target AML Initiative

Blood (2015) 126 (23): 170.

https://doi.org/10.1182/blood.V126.23.170.170

Published: 2015

Journal Articles

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

Yuichiro Nakata, Takeshi Ueda, MD PhD, Akiko Nagamachi, PhD, Linda Wolff, PhD, Ogawa Seishi, MD, Toshiya Inaba, MD, Hiroaki Honda, MD PhD

Blood (2014) 124 (21): 4602.

https://doi.org/10.1182/blood.V124.21.4602.4602

Published: 2014

Journal Articles

C-CBL Is a Critical Negative Regulator of Megakaryopoesis

Sebastian J. Saur, MD, Melanie Märklin, M. Sc., Alexandra Poljak, B. Sc., Manuela Ganser, B. Sc., David E. James, PhD, Kyle Hoehn, PhD, Lothar Kanz, MD, Hans-Georg Kopp, MD, Martin R. Müller, MD PhD

Blood (2014) 124 (21): 1581.

https://doi.org/10.1182/blood.V124.21.1581.1581

Published: 2014

Journal Articles

Platelet FcγRIIA Signaling Results in Ubiquitination and Cellular Translocation of Activated Syk

Shaji Abraham, PhD, Leonard C. Edelstein, PhD, Chad A Shaw, PhD, Pierrette Andre, MS, Xianguo Kong, MD, Carol T Dangelmaier, Alexander Tsygankov, PhD, Paul F Bray, MD, Satya P. Kunapuli, PhD, Steven E. McKenzie, MD PhD

Blood (2014) 124 (21): 2761.

https://doi.org/10.1182/blood.V124.21.2761.2761

Published: 2014

Journal Articles

Overexpression Of Leukemia Associated Cbl Y371H Mutation In Transgenic Mice Causes Dosage Dependent Embryonic Lethality

Kenneth Lieuw, MD, PhD, Jayasree Krishnamurthy, M.S., Mignon L. Loh, MD

Blood (2013) 122 (21): 2515.

https://doi.org/10.1182/blood.V122.21.2515.2515

Published: 2013

Journal Articles

Clinical and Genetic Characterization Of Patients With C-CBL Mutated Juvenile Myelomonocytic Leukemia By Whole-Exome/Deep Sequencing

Blood (2013) 122 (21): 1564.

https://doi.org/10.1182/blood.V122.21.1564.1564

Published: 2013

Journal Articles

Clinical and Genetic Characterization Of Patients With C-CBL Mutated Juvenile Myelomonocytic Leukemia By Whole-Exome/Deep Sequencing

Blood (2013) 122 (21): 1565.

https://doi.org/10.1182/blood.V122.21.1565.1565

Published: 2013

Journal Articles

AVL-292, a Bruton's Tyrosine Kinase Inhibitor Impacts Bone Resorption by Abrogating Osteoclast Sealing Zone Formation in Multiple Myeloma

Homare Eda, Loredana Santo, Diana Cirstea, Andrew J. Yee, Anuj Mahindra, Tyler Scullen, Neeharika Nemani, Yuko Mishima, Erica Evans, Juswinder Singh, Wes Westlin, Noopur Raje

Blood (2012) 120 (21): 1822.

https://doi.org/10.1182/blood.V120.21.1822.1822

Published: 2012

Journal Articles

Flt3 inhibitor AC220 is a potent therapy in a mouse model of myeloproliferative disease driven by enhanced wild-type Flt3 signaling

Samuel J. Taylor, Samantha A. Dagger, Christine B. F. Thien, Matthew E. Wikstrom, Wallace Y. Langdon

Blood (2012) 120 (19): 4049–4057.

https://doi.org/10.1182/blood-2012-06-436675

Published: 2012

Includes: Supplemental data

Journal Articles

CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells

Hiroaki Niiro, Siamak Jabbarzadeh-Tabrizi, Yoshikane Kikushige, Takahiro Shima, Kumiko Noda, Shun-ichiro Ota, Hirofumi Tsuzuki, Yasushi Inoue, Yojiro Arinobu, Hiromi Iwasaki, Shinji Shimoda, Eishi Baba, Hiroshi Tsukamoto, Takahiko Horiuchi, Tadayoshi Taniyama, Koichi Akashi

Blood (2012) 119 (10): 2263–2273.

https://doi.org/10.1182/blood-2011-04-351965

Published: 2012

Journal Articles

FLT3 Inhibitor AC220 Is a Potent Therapy for Myeloproliferative Disease in c-Cbl RING Finger Mutant Mice

Wallace Y Langdon, PhD, Samantha A Dagger, Samuel J Taylor, Christine B F Thien, PhD, Matthew E Wikstrom, PhD

Blood (2011) 118 (21): 642.

https://doi.org/10.1182/blood.V118.21.642.642

Published: 2011

Journal Articles

C-CBL Inactivation Promotes Cytokine-Driven Growth of Human CD34+ Cells and AML1-ETO Expressing Cells

Susumu Goyama, MD, PhD, Janet Schibler, James C. Mulloy, PhD

Blood (2011) 118 (21): 2464.

https://doi.org/10.1182/blood.V118.21.2464.2464

Published: 2011

Journal Articles

Analysis of ASXL1, IDH1, IDH2, c-CBL , and WT1 Mutations in De Novo Acute Myeloid Leukaemia

Mariam Ibañez, Esperanza Such, Jose Cervera, MD, Irene Luna, MD, Sandra Dolz, Inés Gómez-Seguí, MD., Maria López-Pavia, MD, Beatriz Costan, Eva Barragan, PhD, Oscar Fuster, PhD, Marta Llop, Silvestre Oltra, Federico Moscardo, MD, Pau Montesinos, MD, David Martinez-Cuadrón, MD, Miguel A. Sanz, MD, PhD

Blood (2011) 118 (21): 1450.

https://doi.org/10.1182/blood.V118.21.1450.1450

Published: 2011

Journal Articles

Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling

Lorena Buitrago, Wallace Y. Langdon, Archana Sanjay, Satya P. Kunapuli

Blood (2011) 118 (20): 5631–5640.

https://doi.org/10.1182/blood-2011-01-328807

Published: 2011

Includes: Supplemental data

Journal Articles

Arsenic Sulfide Binds c-CBL to Promote BCR-ABL Ubiquitination and Degradation In Chronic Myelogenous Leukemia.

Jian-Hua Mao, Xiao-Yan Sun, Jian-Xiang Liu, Qun-Ye Zhang, Ping Liu, Qiu-Hua Huang, Ke-Qin Li, Xiao-Wei Zhang, Quan Chen, Zhu Chen, Sai-Juan Chen

Blood (2010) 116 (21): 1200.

https://doi.org/10.1182/blood.V116.21.1200.1200

Published: 2010

NARROW

Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells

Src-like Adaptor Protein Promotes the CD103 + dendritic Cell Homeostasis in the Lung

Alteration of Chromatin Modifiers and Misregulation of Transcription Factors Define the Genomic Profile of Infant AML

C-Cbl Regulates c-Mpl Receptor Trafficking and Its Internalization

Cbl Y371H Transgene Combined with Hematopoietic Deletion of the Endogenous c-Cbl Gene Results in GM-CSF Hypersensitivity and Leukocytosis

Comprehensive Genomic and Transcript Profiling of CBL Gene in Childhood AML: A Report from Children's Oncology Group Studies AAML03P1, AAML0531 and COG/NCI Target AML Initiative

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

C-CBL Is a Critical Negative Regulator of Megakaryopoesis

Platelet FcγRIIA Signaling Results in Ubiquitination and Cellular Translocation of Activated Syk

Overexpression Of Leukemia Associated Cbl Y371H Mutation In Transgenic Mice Causes Dosage Dependent Embryonic Lethality

Clinical and Genetic Characterization Of Patients With C-CBL Mutated Juvenile Myelomonocytic Leukemia By Whole-Exome/Deep Sequencing

Clinical and Genetic Characterization Of Patients With C-CBL Mutated Juvenile Myelomonocytic Leukemia By Whole-Exome/Deep Sequencing

AVL-292, a Bruton's Tyrosine Kinase Inhibitor Impacts Bone Resorption by Abrogating Osteoclast Sealing Zone Formation in Multiple Myeloma

Flt3 inhibitor AC220 is a potent therapy in a mouse model of myeloproliferative disease driven by enhanced wild-type Flt3 signaling

CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells

FLT3 Inhibitor AC220 Is a Potent Therapy for Myeloproliferative Disease in c-Cbl RING Finger Mutant Mice

C-CBL Inactivation Promotes Cytokine-Driven Growth of Human CD34+ Cells and AML1-ETO Expressing Cells

Analysis of ASXL1, IDH1, IDH2, c-CBL , and WT1 Mutations in De Novo Acute Myeloid Leukaemia

Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling

Arsenic Sulfide Binds c-CBL to Promote BCR-ABL Ubiquitination and Degradation In Chronic Myelogenous Leukemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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