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Journal Articles

KMT2A-Rearranged Infant Acute Lymphoblastic Leukemia Cells Undergo ER-Stress-Induced Apoptosis Following Exposure to Proteasome Inhibitors

Wonil Kim, PhD, Cary S. Koss, BS, Tanja A. Gruber, MD PhD

Blood (2019) 134 (Supplement_1): 1283.

https://doi.org/10.1182/blood-2019-127699

Published: 2019

Journal Articles

IL-7 Activates a STAT5/PIM1 Axis to Promote T-Cell Acute Lymphoblastic Leukemia Proliferation and Viability in a Bcl-2-Independent Manner

Ribeiro Daniel, PhD, Alice Melão, Msc, Ruben van Boxtel, PhD, Cristina Santos, PhD, Ana Silva, PhD, Milene C Silva, PhD, Bruno António Cardoso, PhD, Paul J. Coffer, PhD Prof, Joao Barata, PhD

Blood (2018) 132 (Supplement 1): 914.

https://doi.org/10.1182/blood-2018-99-113778

Published: 2018

Journal Articles

Selectively Targeting Checkpoint Kinase By Prexasertib Had Potent Anti-Tumor Activity As Single Agent or Combined with Other Chemotherapeutic Drugs in Diffuse Large B-Cell Lymphoma, Especially Double Hit Lymphoma

Juan Gu, MD PhD, Dennis C Gaughan, Simran Gill, Cory Mavis, BSc, MSc, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2018) 132 (Supplement 1): 5151.

https://doi.org/10.1182/blood-2018-99-110282

Published: 2018

Journal Articles

Identification of Tipifarnib Sensitivity Biomarkers in T-Cell Tumor Cell Lines

Ruth Alonso Alonso, PhD, Rufino Mondejar García, PhD, Jose Pedro Vaqué Díez, PhD, Nuria García Díaz, PhDcandidate, Cristina Pérez Menéndez, PhD, Francis Burrows, PhD, Catherine Scholz, PharmD, Antonio Gualberto, PhD MD, Miguel A. Piris, PhD MD

Blood (2018) 132 (Supplement 1): 2851.

https://doi.org/10.1182/blood-2018-99-118291

Published: 2018

Journal Articles

Effects of Proteasome Inhibition in the Anti-Tumor Activity of Venetoclax in Mantle Cell Lymphoma Pre-Clinical Models

Shalin K. Kothari, MD, Cory Mavis, BSc, MSc, Juan Gu, MD PhD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2018) 132 (Supplement 1): 2942.

https://doi.org/10.1182/blood-2018-99-116510

Published: 2018

Journal Articles

Transcriptional Regulation of the CDC42 Signaling Pathway By Ikaros in T-Cell Acute Lymphoblastic Leukemia

Sinisa Dovat, Zheng Ge, MD PhD, Kimberly Payne, Chandrika Gowda, MD, Chunhua Song, MD

Blood (2017) 130 (Supplement 1): 1213.

https://doi.org/10.1182/blood.V130.Suppl_1.1213.1213

Published: 2017

Journal Articles

Suppression of Cdc37 Induces BTZ Resistance through XBP1s Mediated Plasma Cell Immaturation in Multiple Myeloma

Meirong Zang, Lanting LIU, Fengyan Jin, Jiaojiao Guo, An Gang, MD, Xiaoqi Qin, Tao Zhu, Shuhui Deng, Zhang Shuaishuai, MD, Mu Hao, PhD, Xiaoyan Feng, Yan Xu, MD, Wen Zhou, Lugui Qiu, MD

Blood (2017) 130 (Supplement 1): 4350.

https://doi.org/10.1182/blood.V130.Suppl_1.4350.4350

Published: 2017

Journal Articles

Recognition of Recurrent Protein Expression Patterns in Pediatric Acute Myeloid Leukemia Suggests New Therapeutic Targets

Fieke W Hoff, Chenyue W Hu, Yihua Qiu, MD, Suk-Young Yoo, Amina Qutub, Eveline S. de Bont, Terzah M. Horton, MD PhD, Steven M. Kornblau, MD

Blood (2016) 128 (22): 1712.

https://doi.org/10.1182/blood.V128.22.1712.1712

Published: 2016

Journal Articles

Buparlisib/BKM120 PI3 Kinase Therapy in B Cell and T Cell Non-Hodgkin Lymphoma (NHL) and Hodgkin Lymphoma (HL): Identification of Resistance Pathways and Biomarker Discovery

Afshin Beheshti, PhD, Michael E Coyle, MD, Ravi Dashnamoorthy, PhD, Andrew M Evens, DO, MSc, FACP

Blood (2016) 128 (22): 2920.

https://doi.org/10.1182/blood.V128.22.2920.2920

Published: 2016

Journal Articles

Anti-CD38 Targeted Nanoparticles for Drug Delivery in Multiple Myeloma

Pilar De La Puente, PhD, Abbey Jin, Micah John Luderer, BS, MS, Barbara Muz, PhD MSc, Justin A King, Ravi Vij, MD MBA, Abdel Kareem Azab, BPharm, PhD

Blood (2016) 128 (22): 2135.

https://doi.org/10.1182/blood.V128.22.2135.2135

Published: 2016

Journal Articles

LIGHT (TNFSF14) Increases Survival and Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells Via LTβR

Hawk Kim, Sook-Kyoung Heo, PhD, Eui-Kyu Noh, PhD, Gi-Dong Gwon, Jae-Cheol Jo, MD PhD, Yunsuk Choi, MD PhD, Jinny Park

Blood (2016) 128 (22): 4546.

https://doi.org/10.1182/blood.V128.22.4546.4546

Published: 2016

Journal Articles

Essential Role for Phospholipase C Gamma 1 (PLC-γ1) in the Survival of t(8;21) Acute Myeloid Leukemia

Hasan Mahmud, PhD, Frank JG Scherpen, Tiny Meeuwsen-de Boer, Harm-Jan Lourens, Eveline S. de Bont

Blood (2016) 128 (22): 1699.

https://doi.org/10.1182/blood.V128.22.1699.1699

Published: 2016

Journal Articles

XRCC5 Plays an Important Role in Homologous Recombination, Genome Stability and Survival of Myeloma Cells

Edward Laane, MD PhD, Purushothama Nanjappa, Subodh Kumar, PhD, Florence Magrangeas, Stephane Minvielle, Hele Everaus, MD PhD, Kenneth C Anderson, MD, Herve Avet-Loiseau, Masood A Shammas, PhD, Nikhil C. Munshi, MD

Blood (2015) 126 (23): 1218.

https://doi.org/10.1182/blood.V126.23.1218.1218

Published: 2015

Journal Articles

Suppression of Cdc37 Induces Bortezomib Resistance through Autophagy Activation and Plasma Cell Immaturation in Multiple Myeloma

Meirong Zang, Fengyan Jin, Lanting Liu, Gang An, MDPhD, Xiaoqi Qin, MD, Xiaoyan Feng, Yan Xu, MDPhD, Mu Hao, MD PhD, Wen Zhou, PhD, Lugui Qiu, MD PhD

Blood (2015) 126 (23): 2480.

https://doi.org/10.1182/blood.V126.23.2480.2480

Published: 2015

Journal Articles

Increased p53 Expression in Patients with Therapy-Related MDS/AML Is Common and May be Associated with a Poor Prognosis

Su Wai Maung, MBBS, MRCP(UK), Niamh Strahan, MSc, Sarah O'Dowd, M.Sc, John O'Loughlin, Ronan Desmond, MD FRCPath, Johnny McHugh, FRCPath, Michael Jeffers, FRCPath, Helen Enright, MD FRCPI, FRCPath

Blood (2015) 126 (23): 5245.

https://doi.org/10.1182/blood.V126.23.5245.5245

Published: 2015

Journal Articles

Pre-Clinical Investigation of Targeted Therapies for Double Hit Diffuse Large B-Cell Lymphoma (DH-DLBCL)

Priyank P. Patel, MD, Alison Zeccola, Vishala T. Neppalli, MD, Juan J Gu, PhD, Cory Mavis, MSc, Sheila Sait, PhD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2015) 126 (23): 5122.

https://doi.org/10.1182/blood.V126.23.5122.5122

Published: 2015

Journal Articles

Changes in p53 Expression By Immunohistochemistry during Azacitidine Therapy in Patients with MDS Can Predict Overall Prognosis

Su Wai Maung, MBBS, MRCP(UK), Niamh Strahan, M.Sc, Philomena O'Byrne, M.Sc, Sarah O'Dowd, M.Sc, John O'Loughlin, Ronan Desmond, MD FRCPath, Johnny McHugh, FRCPath, Michael Jeffers, FRCPath, Helen Enright, MD FRCPI, FRCPath

Blood (2015) 126 (23): 2878.

https://doi.org/10.1182/blood.V126.23.2878.2878

Published: 2015

Journal Articles

Dual Inhibition of PKC Delta By Carfilzomib (CFZ) and Ibrutinib Results in Synergistic Activity in Rituximab-Chemotherapy Sensitive and Resistant Lymphoma Pre-Clinical Models and in Primary Tumor Cells Isolated from B-Cell Lymphoma Patients

Qunling Zhang, MD PhD, Juan J Gu, PhD, Ye Guo, MD, Jacob Klos, Cory Mavis, MSc, Myron S. Czuczman, MD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2015) 126 (23): 4006.

https://doi.org/10.1182/blood.V126.23.4006.4006

Published: 2015

Journal Articles

The PI3 Kinase (PI3K) Inhibitor, Buparlisib/BKM120, in B-Cell, T-Cell and Hodgkin Lymphoma Cell Lines: Cell Death Studies and Examination of Genomic Pathway Analyses Via a Systems Biology Approach

Michael E Coyle, MD, Ravi Dashnamoorthy, PhD, Afshin Beheshti, PhD, Andrew M. Evens, DO, MSc

Blood (2015) 126 (23): 1555.

https://doi.org/10.1182/blood.V126.23.1555.1555

Published: 2015

Journal Articles

Foxo 3a Signaling Mediates Apoptosis in Lymphoma Cells By the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographis Paniculata

Shuo Yang, Bo Ding, Fei Ying, Jana Svetlichnaya, Austin Tom, Sheila Prachand, Yanzhuang Wang, Leo I Gordon, MD FACP

Blood (2015) 126 (23): 2760.

https://doi.org/10.1182/blood.V126.23.2760.2760

Published: 2015

NARROW

KMT2A-Rearranged Infant Acute Lymphoblastic Leukemia Cells Undergo ER-Stress-Induced Apoptosis Following Exposure to Proteasome Inhibitors

IL-7 Activates a STAT5/PIM1 Axis to Promote T-Cell Acute Lymphoblastic Leukemia Proliferation and Viability in a Bcl-2-Independent Manner

Selectively Targeting Checkpoint Kinase By Prexasertib Had Potent Anti-Tumor Activity As Single Agent or Combined with Other Chemotherapeutic Drugs in Diffuse Large B-Cell Lymphoma, Especially Double Hit Lymphoma

Identification of Tipifarnib Sensitivity Biomarkers in T-Cell Tumor Cell Lines

Effects of Proteasome Inhibition in the Anti-Tumor Activity of Venetoclax in Mantle Cell Lymphoma Pre-Clinical Models

Transcriptional Regulation of the CDC42 Signaling Pathway By Ikaros in T-Cell Acute Lymphoblastic Leukemia

Suppression of Cdc37 Induces BTZ Resistance through XBP1s Mediated Plasma Cell Immaturation in Multiple Myeloma

Recognition of Recurrent Protein Expression Patterns in Pediatric Acute Myeloid Leukemia Suggests New Therapeutic Targets

Buparlisib/BKM120 PI3 Kinase Therapy in B Cell and T Cell Non-Hodgkin Lymphoma (NHL) and Hodgkin Lymphoma (HL): Identification of Resistance Pathways and Biomarker Discovery

Anti-CD38 Targeted Nanoparticles for Drug Delivery in Multiple Myeloma

LIGHT (TNFSF14) Increases Survival and Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells Via LTβR

Essential Role for Phospholipase C Gamma 1 (PLC-γ1) in the Survival of t(8;21) Acute Myeloid Leukemia

XRCC5 Plays an Important Role in Homologous Recombination, Genome Stability and Survival of Myeloma Cells

Suppression of Cdc37 Induces Bortezomib Resistance through Autophagy Activation and Plasma Cell Immaturation in Multiple Myeloma

Increased p53 Expression in Patients with Therapy-Related MDS/AML Is Common and May be Associated with a Poor Prognosis

Pre-Clinical Investigation of Targeted Therapies for Double Hit Diffuse Large B-Cell Lymphoma (DH-DLBCL)

Changes in p53 Expression By Immunohistochemistry during Azacitidine Therapy in Patients with MDS Can Predict Overall Prognosis

Dual Inhibition of PKC Delta By Carfilzomib (CFZ) and Ibrutinib Results in Synergistic Activity in Rituximab-Chemotherapy Sensitive and Resistant Lymphoma Pre-Clinical Models and in Primary Tumor Cells Isolated from B-Cell Lymphoma Patients

The PI3 Kinase (PI3K) Inhibitor, Buparlisib/BKM120, in B-Cell, T-Cell and Hodgkin Lymphoma Cell Lines: Cell Death Studies and Examination of Genomic Pathway Analyses Via a Systems Biology Approach

Foxo 3a Signaling Mediates Apoptosis in Lymphoma Cells By the Diterpenoid Lactone Andrographolide (Andro), the Active Component of Andrographis Paniculata

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American Society of Hematology

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American Society of Hematology

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