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Journal Articles

Structural Basis of Vitamin K Antagonism

Weikai Li, PhD, Shixuan Liu, Shuang Li

Blood (2019) 134 (Supplement_1): 482.

https://doi.org/10.1182/blood-2019-127324

Published: 2019

Journal Articles

Flow Cytometry Assay to Monitor Effectiveness of Gene Therapy Correction in Peripheral Blood Mononuclear Cells of Gaucher Disease Type I Patients

Cecilia Barese, MD PhD, Michael Waring, Richard Pfeifer, PhD DABT, Chris Mason, MD PhD

Blood (2018) 132 (Supplement 1): 5791.

https://doi.org/10.1182/blood-2018-99-119766

Published: 2018

Journal Articles

Vitamin K epoxide reductase: moving closer to nature

Martin J. Shearer

Blood (2018) 132 (18): 1867–1869.

https://doi.org/10.1182/blood-2018-08-869578

Published: 2018

Journal Articles

Evaluation of oral anticoagulants with vitamin K epoxide reductase in its native milieu

Xuejie Chen, Da-Yun Jin, Darrel W. Stafford, Jian-Ke Tie

Blood (2018) 132 (18): 1974–1984.

https://doi.org/10.1182/blood-2018-05-846592

Published: 2018

Includes: Supplemental data

Journal Articles

Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition

Sangwook Wu, Xuejie Chen, Da-Yun Jin, Darrel W. Stafford, Lee G. Pedersen, Jian-Ke Tie

Blood (2018) 132 (6): 647–657.

https://doi.org/10.1182/blood-2018-01-830901

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

Pharmacokinetics of Treosulfan in Patients with Thalassemia Major Undergoing Allogeneic Hematopoietic Stem Cell Transplantation — a Comparison of Two Formulations and Correlation with Clinical Outcomes

Alok Srivastava, MD, Ezhilpavai Mohanan, Msc, Raveen Stephen Stallon Illangeswaran, M.Sc.,, Carl Panetta, PhD, Kavitha M Lakshmi, MSc, Anu Korula, MD DM, Aby Abraham, MD DM, Biju George, MDDM, Vikram Mathews, MD DM, Poonkuzhali Balasubramanian, MSc, PhD

Blood (2017) 130 (Supplement 1): 3219.

https://doi.org/10.1182/blood.V130.Suppl_1.3219.3219

Published: 2017

Journal Articles

Deeper understanding of carboxylase

James H. Morrissey

Blood (2016) 127 (15): 1841–1842.

https://doi.org/10.1182/blood-2016-02-694927

Published: 2016

Journal Articles

Genetic Defects in 10 Index Cases of Inherited Vitamin K Dependent Clotting Factors Deficiency

Arshi Naz, MSc.PhD, Mattiha Watzaska, Johannes Oldenburg, Inga Kristin, Ali mohammad Waryah, Ali Raza, Mohammad Nadeem, M.B;B.D, FCPS, Nisar Ahmed, FCPS haematology, Tahir Shamsi, MBBS, MRCPath,FRCPath

Blood (2015) 126 (23): 4705.

https://doi.org/10.1182/blood.V126.23.4705.4705

Published: 2015

Journal Articles

Warfarin Inhibits Vitamin K Epoxide Reductase By Specifically Blocking at a Conformational and Redox State

Guomin Shen, Hao Zhang, Weidong Cui, Evan Sadler, Michael Gross, Weikai Li, PhD

Blood (2014) 124 (21): 4214.

https://doi.org/10.1182/blood.V124.21.4214.4214

Published: 2014

Journal Articles

VKORc1 Is Under-Expressed in Skeletal Muscle of Humans, Dogs and Mice: Potential Implications for Ectopic Coagulation Factor Expression in Pre-Clinical and Therapeutic Applications

Courtney T Connolly, Armida Faella, Timothy C. Nichols, MD, Katherine A. High, MD, Valder R. Arruda, MD, PhD, Paris Margaritis, DPhil

Blood (2014) 124 (21): 1477.

https://doi.org/10.1182/blood.V124.21.1477.1477

Published: 2014

Journal Articles

A Cyclopropane-Derived Stable Analog Of Fd-895 Induces Apoptosis and Inhibition Of mRNA Splicing In Lymphoma and Chronic Lymphocytic Leukemia: A Novel Therapeutic Approach

Deepak Kumar, PhD, Manoj Kumar Kashyap, PhD, Ide Spaanderman, BS, Reymundo Villa, PhD, Laura Rassenti, PhD, James La Clair, PhD, Michael D. Burkat, PhD, Thomas J. Kipps, MD, PhD, Januario E. Castro, M.D.

Blood (2013) 122 (21): 2884.

https://doi.org/10.1182/blood.V122.21.2884.2884

Published: 2013

Journal Articles

Evaluation Of CYP450 and Transporter-Mediated Drug-Drug Interaction Potential Of Pomalidomide In Healthy Men and In Vitro

Claudia Kasserra, PhD, Mahmoud Assaf, MS, MBA, Matthew Hoffmann, PhD, Yan Li, PhD, Liangang Liu, PhD, Xiaomin Wang, PhD, Gondi Kumar, PhD, Maria Palmisano, MD

Blood (2013) 122 (21): 1989.

https://doi.org/10.1182/blood.V122.21.1989.1989

Published: 2013

Journal Articles

The Dynamic Motion and Delicate Control Of Vkor Catalysis

Weikai Li, PhD

Blood (2013) 122 (21): 2330.

https://doi.org/10.1182/blood.V122.21.2330.2330

Published: 2013

Journal Articles

Polymorphisms in VKORC1, CYP2C9, and CYP4F2 and Warfarin Dose in the Pediatric Population

Susan I. Vear, MD, Gregory D. Ayers, MS, C. Michael Stein, MD, MBChB, Richard H. Ho, MD, MSCI

Blood (2012) 120 (21): 4358.

https://doi.org/10.1182/blood.V120.21.4358.4358

Published: 2012

Journal Articles

The VKORC1 and CYP2C9 Genotypes Significantly Affect Vitamin K Antagonist Dosing Only in Patients Aged 20 Years or Older

Ulrike Nowak-Gottl, MD, Kevin Dietrich, Andre Franke, Noha Sharaf El-Din, Yutaka Yasui, Lesley G Mitchell

Blood (2011) 118 (21): 1243.

https://doi.org/10.1182/blood.V118.21.1243.1243

Published: 2011

Journal Articles

Prolonged Coagulopathy Secondary to Superwarfarin Brodifacoum Rodenticide Ingestion

Abhinav B. Chandra, MD, MSc, Nanda K. Methuku, MD, MPH, Yiwu Huang, MD, PhD

Blood (2010) 116 (21): 4425.

https://doi.org/10.1182/blood.V116.21.4425.4425

Published: 2010

Journal Articles

Compound Heterozygosity of a W493C Substitution and R704/Premature Stop Codon within the γ-Glutamyl Carboxylase in Combined Vitamin K-Dependent Coagulation Factor Deficiency in a French Family.

Dhouha Darghouth, PhD, Kevin W Hallgren, Odile Issertial, Amine Bazaa, PhD, Kathleen L Berkner, PhD, Jean-Philippe Rosa, MD, PhD, Rémi Favier, MD

Blood (2009) 114 (22): 1302.

https://doi.org/10.1182/blood.V114.22.1302.1302

Published: 2009

Journal Articles

Analysis of the Anti-Leukemia Mechanism of Parthenolide.

ShanShan Pei, Monica L. Guzman, PhD, Shama Nasim, Lei Shi, Peter A Crooks, PhD, Craig T. Jordan, PhD

Blood (2009) 114 (22): 2734.

https://doi.org/10.1182/blood.V114.22.2734.2734

Published: 2009

Journal Articles

Pharmacokinetics, Metabolism, Distribution and Excretion of Carfilzomib in Rats.

Jinfu Yang, Rachel Fang, Zhengping Wang, Jing Jiang, Tony Muchamuel, Susan Lee, Christopher J Kirk, Francisco Zhao, Mark K Bennett, Christopher J. Molineaux

Blood (2009) 114 (22): 2754.

https://doi.org/10.1182/blood.V114.22.2754.2754

Published: 2009

Journal Articles

VKORC1 V66M Mutation in African Brazilian Patient Resistant to Oral Anticoagulant Therapy.

Fernanda A. Orsi, MD, Joyce Maria Annichino-Bizzacchi, MD, PhD, Erich Vinicius de Paula, MD, PhD, Michael R Langley, Karen Weck

Blood (2009) 114 (22): 2102.

https://doi.org/10.1182/blood.V114.22.2102.2102

Published: 2009

NARROW

Structural Basis of Vitamin K Antagonism

Flow Cytometry Assay to Monitor Effectiveness of Gene Therapy Correction in Peripheral Blood Mononuclear Cells of Gaucher Disease Type I Patients

Vitamin K epoxide reductase: moving closer to nature

Evaluation of oral anticoagulants with vitamin K epoxide reductase in its native milieu

Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition

Pharmacokinetics of Treosulfan in Patients with Thalassemia Major Undergoing Allogeneic Hematopoietic Stem Cell Transplantation — a Comparison of Two Formulations and Correlation with Clinical Outcomes

Deeper understanding of carboxylase

Genetic Defects in 10 Index Cases of Inherited Vitamin K Dependent Clotting Factors Deficiency

Warfarin Inhibits Vitamin K Epoxide Reductase By Specifically Blocking at a Conformational and Redox State

VKORc1 Is Under-Expressed in Skeletal Muscle of Humans, Dogs and Mice: Potential Implications for Ectopic Coagulation Factor Expression in Pre-Clinical and Therapeutic Applications

A Cyclopropane-Derived Stable Analog Of Fd-895 Induces Apoptosis and Inhibition Of mRNA Splicing In Lymphoma and Chronic Lymphocytic Leukemia: A Novel Therapeutic Approach

Evaluation Of CYP450 and Transporter-Mediated Drug-Drug Interaction Potential Of Pomalidomide In Healthy Men and In Vitro

The Dynamic Motion and Delicate Control Of Vkor Catalysis

Polymorphisms in VKORC1, CYP2C9, and CYP4F2 and Warfarin Dose in the Pediatric Population

The VKORC1 and CYP2C9 Genotypes Significantly Affect Vitamin K Antagonist Dosing Only in Patients Aged 20 Years or Older

Prolonged Coagulopathy Secondary to Superwarfarin Brodifacoum Rodenticide Ingestion

Compound Heterozygosity of a W493C Substitution and R704/Premature Stop Codon within the γ-Glutamyl Carboxylase in Combined Vitamin K-Dependent Coagulation Factor Deficiency in a French Family.

Analysis of the Anti-Leukemia Mechanism of Parthenolide.

Pharmacokinetics, Metabolism, Distribution and Excretion of Carfilzomib in Rats.

VKORC1 V66M Mutation in African Brazilian Patient Resistant to Oral Anticoagulant Therapy.

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American Society of Hematology

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