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Journal Articles

The endoplasmic reticulum protein SEC22B interacts with NBEAL2 and is required for megakaryocyte α-granule biogenesis

Richard W. Lo, Ling Li, Fred G. Pluthero, Richard Leung, Koji Eto, Walter H. A. Kahr
Journal: Blood
Blood (2020) 136 (6): 715–725.
https://doi.org/10.1182/blood.2019004276
Published: 2020
Includes: Supplemental data
Journal Articles

The microenvironmental niche in classic Hodgkin lymphoma is enriched for CTLA-4–positive T cells that are PD-1–negative

Sanjay S. Patel, Jason L. Weirather, Mikel Lipschitz, Ana Lako, Pei-Hsuan Chen, Gabriel K. Griffin, Philippe Armand, Margaret A. Shipp, Scott J. Rodig
Journal: Blood
Blood (2019) 134 (23): 2059–2069.
https://doi.org/10.1182/blood.2019002206
Published: 2019
Includes: Supplemental data
Journal Articles

The Transmembrane Receptor Roundabout 1 (ROBO1) Is Necessary for Multiple Myeloma Proliferation and Homing to the Bone Marrow Niche

Giada Bianchi, MD, Peter G. Czarnecki, MD, Matthew Ho, PhD, Aldo M. Roccaro, MD PhD, Antonio Sacco, RN, Yawara Kawano, MD PhD, Anil Aktas Samur, PhD, Annamaria Gulla, MD, Tianzeng Chen, Kenneth Wen, Xinchen Wu, Yu-Tzu Tai, PhD, Gulden Camci-Unal, PhD, Irene M. Ghobrial, MD, Ruben D. Carrasco, MD PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 507.
https://doi.org/10.1182/blood-2019-128778
Published: 2019
Journal Articles

T Cell Determinants of Response and Resistance to PD-1 Blockade in Richter's Transformation

Erin Parry, MD PhD, Camilla K Lemvigh, MSc, Annabelle J Anandappa, MD, Shuqiang Li, PhD, Lillian Werner, MS, Ana Lako, Noelia Purroy, MD PhD, Satyen H Gohil, PhD, M.B.,B.S., Giacomo Oliveira, PhD, Pavan Bachireddy, MD, Teddy Huang, Ignaty Leshchiner, PhD, Aina Zurita Martinez, Lars Ronn Olsen, PhD, Kenneth Livak, PhD, Gad Getz, PhD, Donna S Neuberg, ScD, Scott J Rodig, MD PhD, William G. Wierda, MD PhD, Peter Kharchenko, PhD, Nitin Jain, MD, Catherine J. Wu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 680.
https://doi.org/10.1182/blood-2019-125904
Published: 2019
Journal Articles

The Unfolded Protein Response Causes Prothrombotic Transformation of Pancreatic Cancer Linking Tumor Progression with Cancer-Associated Thrombosis

Oluwatoyosi Muse, PhD, Rushad Patell, MD, Christian Peters, PhD, Sol Schulman, MD PhD, Emale Darzi, MS, Calvin Schuster, BA, Ling Huang, PhD, Shibani Mukherjee, PhD, Senthil Muthuswamy, PhD, Jeffrey I. Zwicker, MD, Robert C. Flaumenhaft, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 632.
https://doi.org/10.1182/blood-2019-123544
Published: 2019
Journal Articles

Spatial Mapping of Myelopoiesis Reveals the Bone Marrow Niche for Monocyte Dendritic Cell Progenitors

Jizhou Zhang, Qingqing Wu, PhD, Courtney Johnson, BS, André Olsson, MS, PhD, Anastasiya Slaughter, BA, Margot Lindsay May, BS, Benjamin Weinhaus, BS, Emily Bowers, PhD, James Douglas Engel, PhD, Jean X. Jiang, PhD, Sherry L. Abboud-Werner, PhD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD, Daniel Lucas-Alcaraz, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 528.
https://doi.org/10.1182/blood-2019-128809
Published: 2019
Journal Articles

Mitochondrial Complex II in Intestinal Epithelial Cells Is a Critical Metabolic Checkpoint That Regulates Severity of Gastrointestinal Graft-Versus-Host Disease

Hideaki Fujiwara, Anna V Mathew, Ilya Kovalenko, Pal Anupama, Dan Peltier, Stephanie Kim, Austin Taylor, BA, Katherine Oravecz-Wilson, Yaping Sun, Costas Lyssiotis, Alnawaz Rehemtulla, Subramanian Pennarthur, Pavan Reddy
Journal: Blood
Blood (2019) 134 (Supplement_1): 584.
https://doi.org/10.1182/blood-2019-126775
Published: 2019
Journal Articles

Plasma EDA Fibronectin in Primary Myelofibrosis Correlates with Bone Marrow Fibrosis and Predicts Splenomegaly

Alessandro Malara, PhD, Cristian Gruppi, PhD, Margherita Massa, Vittorio Rosti, MD, Giovanni Barosi, Alessandra Balduini, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1688.
https://doi.org/10.1182/blood-2019-130735
Published: 2019
Journal Articles

Accumulation of Endogenous DNA Damage Sustain Malignant Progression and Increase Therapy Resistance in Multiple Myeloma

Maria Gkotzamanidou, MD PhD, Evangelos Terpos, MD PhD, Nikhil C. Munshi, MD, Vassilis L. Souliotis, PhD, Meletios A. Dimopoulos, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1788.
https://doi.org/10.1182/blood-2019-123502
Published: 2019
Journal Articles

Altered Structure and Function of Mesenchymal Stromal Cell-Derived Extracellular Matrix in MDS Can be Restored By Luspatercept

Manja Wobus, PhD, Anna Mies, Valentina Magno, PhD, Cindy Welzel, Susann Winter, PhD, Friedrich Stoelzel, MD, Carsten Werner, PhD, Martin Bornhaeuser, MD, Uwe Platzbecker, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1699.
https://doi.org/10.1182/blood-2019-129814
Published: 2019
Journal Articles

VWF Exocytosis and Biogenesis of Weibel Palade Bodies in Endothelial Cells Are Differentially Controlled By Interactions between Bloc-2 and the Exocyst Complex

Anish V. Sharda, MBBS, MPH, Joshua Harrison, BS, Adrian R. Wilkie, PhD, Chao Fang, PhD, Lourdes M. Mendez, MD PhD, Joseph E. Italiano, Jr., BS, PhD, Robert C. Flaumenhaft, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 8.
https://doi.org/10.1182/blood-2019-127712
Published: 2019
Journal Articles

Tyrosine Kinase Inhibitors (TKIs) Targeting Syk and BTK Signaling Differentially Affect PI3K Signalosome Organization and Platelet Function

Tony Zheng, Elizabeth R Lofurno, Sarah Elgamal, Alexander R Melrose, Jiaqing Pang, Joseph J Shatzel, MD, Owen J T McCarty, PhD, Joseph Aslan, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2074.
https://doi.org/10.1182/blood-2019-129066
Published: 2019
Journal Articles

Clinical and Immunologic Activity of Ipilimumab Following Decitabine Priming in Post-Allogeneic Transplant and Transplant-Naïve Patients with Relapsed or Refractory Myelodysplastic Syndromes and Acute Myeloid Leukemia: A Multi-Center Phase 1, Two-Arm, Dose-Escalation Study

Jacqueline S Garcia, MD, Lillian Werner, Benjamin K. Tomlinson, MD, Michael Keng, MD, Myrna Nahas, MD, Andrew Brunner, MD, Samer K. Khaled, MD, Alexandra Savell, BS, Marlise Luskin, MDMS, David P. Steensma, MD, Martha Wadleigh, MD, Eric S. Winer, MD, Edwin P. Alyea, III, MD, Corey Cutler, MD MPH, FRCPC, Vincent T. Ho, MD, Donna S Neuberg, ScD, Nicole Cullen, Andreas Kantartzis, Ana Lako, Scott Rodig, MD PhD, R. Coleman Lindsley, MD PhD, Yael Flamand, Claire Manuszak, Ryan Brennick, Mariano Severgnini, Stephanie Andrews, Ilene Galinsky, Pavan Bachireddy, MD, Yohei Arihara, MD PhD, Jerome Ritz, MD, Matthew S. Davids, MD, Howard Streicher, MD, Catherine J. Wu, MD, Richard M. Stone, MD, Daniel J. DeAngelo, MD, Robert J. Soiffer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2015.
https://doi.org/10.1182/blood-2019-126238
Published: 2019
Journal Articles

Super-Resolution Immunofluorescence Imaging of Platelet Granules

Maurice Swinkels, MSc, BSc, Johan A. Slotman, PhD, Frank W.G. Leebeek, MD PhD, Jan Voorberg, PhD, Ruben Bierings, PhD, Gerard Jansen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3613.
https://doi.org/10.1182/blood-2019-124353
Published: 2019
Journal Articles

Direct Visualization of Circulating Neutrophil Extracellular Traps Using Cell Fluorescence during Human Septic Shock-Induced Disseminated Intravascular Coagulation

Laure Stiel, MD, Caroline Mayeur-Rousse, MD, Julie Helms, Fehrat Meziani, Laurent Mauvieux, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3583.
https://doi.org/10.1182/blood-2019-124698
Published: 2019
Journal Articles

YAP and TAZ in Fibroblastic Reticular Cells Support Hematopoiesis and Retention of Lymphocytes in Lymph Nodes

Hyunsoo Cho, MD PhD, Yu Ri Kim, MD, Jieun Jang, MD, Haerim Chung, MD, Soo-Jeong Kim, Sung Yong Choi, Bae Hosung, Ralf Adams, Burkhard Ludewig, PhD, Jin Seok Kim, MD PhD, June-Won Cheong, MD PhD, Yoo Hong Min, MD PhD, Gou Young Koh
Journal: Blood
Blood (2019) 134 (Supplement_1): 3595.
https://doi.org/10.1182/blood-2019-124625
Published: 2019
Journal Articles

Development of a Human in Vitro Cell Model for Haemophilia a

Rosa Toenges, MD, Nadin Hodroj, Nina Kurrle, PhD, Wolfgang Miesbach, MD PhD, Frank Schnuetgen, PhD, Hubert Serve, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3634.
https://doi.org/10.1182/blood-2019-121908
Published: 2019
Journal Articles

Gas6 Targeting Promotes Major Bleeding and Aggravates Inflammation in Protein S Deficient Mice

Raja Eladnani Prince, PhD MSc, Sara Calzavarini, PhD, Claudia Quarroz, BMA, Maria Desiré Reina Caro, BMA, Manuel Schuepbach, BSc, Francois Saller, PhD, Anne Angelillo-Scherrer, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3636.
https://doi.org/10.1182/blood-2019-129037
Published: 2019
Journal Articles

Pharmacodynamic Effects and Immune Correlates of Response to the CD20/CD3 Bispecific Antibody Mosunetuzumab in Relapsed or Refractory Non-Hodgkin Lymphoma

Genevive Hernandez, PhD, Ling-Yuh Huw, PhD, Anton Belousov, PhD, Deanna Wilson, MS, Hartmut Koeppen, MD PhD, Ron McCord, PhD, Kun Peng, PhD, Nancy L Bartlett, MD, Lihua E Budde, MD PhD, Sarit Assouline, MD, Loretta J. Nastoupil, MD MSc, Dok Hyun Yoon, MD PhD, Matthew J Matasar, MD, Brendan Bender, PhD, Antonia Kwan, MD PhD MRCPCH, Chi-Chung Li, PhD, Carol O'Hear, MD PhD, Shen Yin, PhD, Michael C Wei, MD PhD, Joanne I Adamkewicz, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1585.
https://doi.org/10.1182/blood-2019-123933
Published: 2019
Journal Articles

Phenotypic Characterization of the Immune Landscape in the Bone Marrow of Patients with Acute Myeloid Leukemia (AML) Using MultiOmyx TM Hyperplexed Immunofluorescence Assay

Qingyan Au, PhD, Arezoo Hanifi, PhD, Erinn Parnell, PhD, Judy Kuo, Eric Leones, Flora Sahafi, Mate Nagy, PhD, Josette William, MD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1455.
https://doi.org/10.1182/blood-2019-122206
Published: 2019