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Bryan Manning
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Journal Articles

The Mevalonate Pathway Is a Therapeutic Target in TP53 Mutant Acute Myeloid Leukemia

Sarah Skuli, A'Ishah Bakayoko, Gerald Wertheim, Owen Riley, Marisa Kruidenier, Bryan Manning, Akmal Salimov, Gisela Brake-Silla, Derek Dopkin, Jimmy Xu, Eva Nee, Lorelai Mesaros, Ryan Hausler, Manuela Lavorato, Eiko Ogiso, Marni Falk, Kara Maxwell, Nicolas Skuli, Clementina Mesaros, Martin Carroll
Journal: Blood
Blood (2023) 142 (Supplement 1): 408.
https://doi.org/10.1182/blood-2023-185059
Published: 2023
Journal Articles

Targeting the Mevalonate Pathway in the Mitochondria-Dependent Chemotherapy Resistance of TP53 Mutant Acute Myeloid Leukemia

Sarah Skuli, A'Ishah Bakayoko, Bryan Manning, Gerald Wertheim, Jimmy Xu, Eva Nee, Lorelai Mesaros, Ryan Hausler, Manuela Lavorato, Eiko Ogiso, Marni Falk, Kara N. Maxwell, Nicolas Skuli, Clementina Mesaros, Martin P. Carroll
Journal: Blood
Blood (2022) 140 (Supplement 1): 8791–8792.
https://doi.org/10.1182/blood-2022-165660
Published: 2022
Journal Articles

FLT3 Inhibition Downregulates EZH2 in AML and Promotes Myeloid Differentiation

Pamela J. Sung, Simone Sidoli, Simone S. Riedel, Katarzyna Kulej, Hongbo Xie, Bryan Manning, Daniel Tsai, Gerald Wertheim, Benjamin A. Garcia, Sara E. Meyer, Kathrin M. Bernt, Martin P. Carroll
Journal: Blood
Blood (2021) 138 (Supplement 1): 785.
https://doi.org/10.1182/blood-2021-147313
Published: 2021
Journal Articles

Activated natural killer cells predict poor clinical prognosis in high-risk B- and T-cell acute lymphoblastic leukemia

Caroline Duault, Anil Kumar, Adeleh Taghi Khani, Sung June Lee, Lu Yang, Min Huang, Christian Hurtz, Bryan Manning, Lucy Ghoda, Tinisha McDonald, Norman J. Lacayo, Kathleen M. Sakamoto, Martin Carroll, Sarah K. Tasian, Guido Marcucci, Jianhua Yu, Michael A. Caligiuri, Holden T. Maecker, Srividya Swaminathan
Journal: Blood
Blood (2021) 138 (16): 1465–1480.
https://doi.org/10.1182/blood.2020009871
Published: 2021
Includes: Supplemental data
Journal Articles

Activated Natural Killer Cells Are Associated with Poor Clinical Prognosis in High-Risk B- and T- Cell Acute Lymphoblastic Leukemia

Caroline Duault, PharmD, PhD, Anil Kumar, PhD, Adeleh Taghi Khani, PhD, Sung June Lee, BA, Lu Yang, PhD, Min Huang, PhD, Christian Hurtz, PhD, Bryan Manning, BS, Lucy Ghoda, PhD, Tinisha McDonald, BS, Norman J. Lacayo, MD, Kathleen M. Sakamoto, MD PhD, Martin P. Carroll, MD, Guido Marcucci, MD, Jianhua Yu, PhD, Michael A. Caligiuri, MD, Holden T. Maecker, PhD, Srividya Swaminathan, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39.
https://doi.org/10.1182/blood-2020-140044
Published: 2020
Journal Articles

Oncogene-Independent Adaptation of Pre-B Cell Receptor Signaling Confers Drug Resistance and Signaling Plasticity in Ph-like ALL

Christian Hurtz, PhD, Gerald Wertheim, MD, PhD, Joseph Patrick Loftus, BS, Daniel Blumenthal, PhD, Anne Lehman, Yong Li, Bryan Manning, Katherine D Cummins, BMBS, Janis K Burkhardt, PhD, Alexander E. Perl, MD, Martin Carroll, MD, Sarah K. Tasian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 747.
https://doi.org/10.1182/blood-2019-123514
Published: 2019