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Journal Articles

Targeting the plasticity of mesenchymal stromal cells to reroute the course of acute myeloid leukemia

Blood (2021) 138 (7): 557–570.

https://doi.org/10.1182/blood.2020009845

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Therapeutic Applications of a Unique Calcium Channel Blocker to Target SF3B1 MDS

Sunisa Kongkiatkamon, Anand Tiwari, Vera Adema, PhD, Cassandra M Kerr, MS, Bartlomiej Przychodzen, Hassan Awada, Jibran Durrani, Yvonne Parker, Drew Adams, Yuriy Fedorov, Hetty E. Carraway, MD MBA, Chao-Yie Yang, Mikkael A. Sekeres, MD MS, Daniel J. Lindner, James G Phillips, PhD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2019) 134 (Supplement_1): 881.

https://doi.org/10.1182/blood-2019-128671

Published: 2019

Journal Articles

Precision Targeting of Ion Channel Blocker for the Treatment of AML

David Marshall, BS, Antonella Chillemi, PhD, Fabio Malavasi, MD, James Prudent, PhD

Blood (2017) 130 (Supplement 1): 5203.

https://doi.org/10.1182/blood.V130.Suppl_1.5203.5203

Published: 2017

Journal Articles

Red Cell Transport Abnormalities As Predictors of the Development of Renal Disease in Children with Sickle Cell Disease

Sanjay Tewari, MBBS, MRCPCH, John Gibson, Stephan Menzel, PhD, Anke Hannemann, Swee Lay Thein, MD, Bukola T Gbotosho, Halima W M Al Balushi, David C Rees, MA, FRCP

Blood (2016) 128 (22): 1317.

https://doi.org/10.1182/blood.V128.22.1317.1317

Published: 2016

Journal Articles

Upregulation of Hepatocellular NTBI Clearance Following Iron Loading Is Associated with Modulation of Membrane T- and L-Type Calcium Channels

Edith Wiener, MD FRCPath, Roozina Rafique, BSc PhD, Arnold Pizzey, Tomas Adejumo, BSc, George Chennell, BSc, John B Porter, MD, FRCP, FRCPath

Blood (2011) 118 (21): 1038.

https://doi.org/10.1182/blood.V118.21.1038.1038

Published: 2011

Journal Articles

Human Platelets Express Functional Pannexin-1

Jaime Pereira, MD, Kenji F Shoji, Anibal A Vargas, Juan A Orellana, Claudia G Saez, Ph.D., Karla Pereira, Cathy Paddock, Christopher Kuckleburg, PhD, Peter J. Newman, PhD, Diego Mezzano, MD, Juan C Sáez, Ph.D.

Blood (2011) 118 (21): 1132.

https://doi.org/10.1182/blood.V118.21.1132.1132

Published: 2011

Journal Articles

Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers

Serena Pillozzi, Marika Masselli, Emanuele De Lorenzo, Benedetta Accordi, Emanuele Cilia, Olivia Crociani, Amedeo Amedei, Marinella Veltroni, Massimo D'Amico, Giuseppe Basso, Andrea Becchetti, Dario Campana, Annarosa Arcangeli

Blood (2011) 117 (3): 902–914.

https://doi.org/10.1182/blood-2010-01-262691

Published: 2011

Includes: Supplemental data

Journal Articles

Carbon Nanotubes Activate Platelets by Facilitating Extracellular Ca 2+ Influx

Jana Semberova, M.D., Karel Holada, PhD, Olga Simakova, Ph.D., Monique P. Gelderman-Fuhrmann, Ph.D., Jan Simak, Ph.D.

Blood (2008) 112 (11): 992.

https://doi.org/10.1182/blood.V112.11.992.992

Published: 2008

Journal Articles

A Macromolecular Signaling Complex Formed by CXCR4, VLA4 and hERG1 K + Channels Mediates Bone Marrow-Induced Chemo-Resistance in Childhood Acute Lymphoblastic Leukemias: Shortcoming Effects of hERG1 Channels Inhibitors.

Serena Pillozzi, Marika Masselli, Amedeo Amedei, Giuseppe Gaipa, Andrea Biondi, Dario Campana, MD, PhD, Andrea Becchetti, Annarosa Arcangeli, MD, PhD

Blood (2008) 112 (11): 1629.

https://doi.org/10.1182/blood.V112.11.1629.1629

Published: 2008

Journal Articles

Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia

Kenneth I. Ataga, Wally R. Smith, Laura M. De Castro, Paul Swerdlow, Yogen Saunthararajah, Oswaldo Castro, Elliot Vichinsky, Abdullah Kutlar, Eugene P. Orringer, Greg C. Rigdon, Jonathan W. Stocker

Blood (2008) 111 (8): 3991–3997.

https://doi.org/10.1182/blood-2007-08-110098

Published: 2008

Includes: Supplemental data

Journal Articles

DMT1-Independent Uptake of Non-Transferrin Bound Iron into Human Hepatoma Cells Is Selectively Modulated by T-Type Voltage-Dependent Calcium Channel Inhibitors.

Roozina Rafique, BSc, PhD, Monica S.D. Mascarenhas, BSc, MSc, Bala S. Ramesh, BSc, PhD, Kaila S. Srai, BSc, PhD, John B. Porter, MA,MD,FRCP,FRCPath

Blood (2006) 108 (11): 1542.

https://doi.org/10.1182/blood.V108.11.1542.1542

Published: 2006

Journal Articles

A 48-Week Open-Label Study of Senicapoc (ICA-17043), a Gardos Channel Blocker, in Patients with Sickle Cell Disease.

Paul Swerdlow, MD, Kenneth Ataga, MD, Wally Smith, MD, Yogen Saunthararajah, MD, Jonathan W. Stocker, PhD

Blood (2006) 108 (11): 685.

https://doi.org/10.1182/blood.V108.11.685.685

Published: 2006

Journal Articles

G-protein–gated inwardly rectifying potassium channels regulate ADP-induced cPLA 2 activity in platelets through Src family kinases

Haripriya Shankar, Bryan N. Kahner, Janani Prabhakar, Parth Lakhani, Soochong Kim, Satya P. Kunapuli

Blood (2006) 108 (9): 3027–3034.

https://doi.org/10.1182/blood-2006-03-010330

Published: 2006

Journal Articles

Reversible inhibition of the platelet procoagulant response through manipulation of the Gardos channel

Jef L. Wolfs, Simone J. Wielders, Paul Comfurius, Theo Lindhout, John C. Giddings, Robert F. Zwaal, Edouard M. Bevers

Blood (2006) 108 (7): 2223–2228.

https://doi.org/10.1182/blood-2006-01-009613

Published: 2006

Journal Articles

Role of G-Protein Coupled Inwardly Rectifying Potassium (GIRK) Channels in ADP-Mediated Thromboxane A2 Generation.

Haripriya Shankar, B.S, Janani Prabhakar, Parth Lakhani, Satya P. Kunapuli, Ph.D.

Blood (2004) 104 (11): 1565.

https://doi.org/10.1182/blood.V104.11.1565.1565

Published: 2004

Journal Articles

Murine Spherocytosis: Evidence for a Functional Interaction between Protein 4.1 and Na/H Exchange and for a “Protective” Role of the Gardos Channel Against Hemolysis.

Lucia De Franceschi, MD, Alicia Rivera, PhD, Isabel Bize, PhD, Mark Fleming, MD, PHD, Luanne L. Peters, PhD, Philippe Gascard, PhD, Narla Mohandas, PhD, Carlo Brugnara, MD

Blood (2004) 104 (11): 578.

https://doi.org/10.1182/blood.V104.11.578.578

Published: 2004

Journal Articles

Role of G protein–gated inwardly rectifying potassium channels in P2Y 12 receptor–mediated platelet functional responses

Haripriya Shankar, Swaminathan Murugappan, Soochong Kim, Jianguo Jin, Zhongren Ding, Kevin Wickman, Satya P. Kunapuli

Blood (2004) 104 (5): 1335–1343.

https://doi.org/10.1182/blood-2004-01-0069

Published: 2004

Journal Articles

Lysophosphatidic acid opens a Ca ++ channel in human erythrocytes

Lu Yang, Dina A. Andrews, Philip S. Low

Blood (2000) 95 (7): 2420–2425.

https://doi.org/10.1182/blood.V95.7.2420

Published: 2000

NARROW

Targeting the plasticity of mesenchymal stromal cells to reroute the course of acute myeloid leukemia

Therapeutic Applications of a Unique Calcium Channel Blocker to Target SF3B1 MDS

Precision Targeting of Ion Channel Blocker for the Treatment of AML

Red Cell Transport Abnormalities As Predictors of the Development of Renal Disease in Children with Sickle Cell Disease

Upregulation of Hepatocellular NTBI Clearance Following Iron Loading Is Associated with Modulation of Membrane T- and L-Type Calcium Channels

Human Platelets Express Functional Pannexin-1

Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers

Carbon Nanotubes Activate Platelets by Facilitating Extracellular Ca 2+ Influx

A Macromolecular Signaling Complex Formed by CXCR4, VLA4 and hERG1 K + Channels Mediates Bone Marrow-Induced Chemo-Resistance in Childhood Acute Lymphoblastic Leukemias: Shortcoming Effects of hERG1 Channels Inhibitors.

Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia

DMT1-Independent Uptake of Non-Transferrin Bound Iron into Human Hepatoma Cells Is Selectively Modulated by T-Type Voltage-Dependent Calcium Channel Inhibitors.

A 48-Week Open-Label Study of Senicapoc (ICA-17043), a Gardos Channel Blocker, in Patients with Sickle Cell Disease.

G-protein–gated inwardly rectifying potassium channels regulate ADP-induced cPLA 2 activity in platelets through Src family kinases

Reversible inhibition of the platelet procoagulant response through manipulation of the Gardos channel

Role of G-Protein Coupled Inwardly Rectifying Potassium (GIRK) Channels in ADP-Mediated Thromboxane A2 Generation.

Murine Spherocytosis: Evidence for a Functional Interaction between Protein 4.1 and Na/H Exchange and for a “Protective” Role of the Gardos Channel Against Hemolysis.

Role of G protein–gated inwardly rectifying potassium channels in P2Y 12 receptor–mediated platelet functional responses

Lysophosphatidic acid opens a Ca ++ channel in human erythrocytes

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American Society of Hematology

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American Society of Hematology

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