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Journal Articles

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, Daniel Bilbao, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD

Blood (2019) 134 (Supplement_1): 3972.

https://doi.org/10.1182/blood-2019-121847

Published: 2019

Journal Articles

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

Shailaja N Hegde, PhD, Huzoor Akbar, PhD, Shawnagay Nestheide, BS, Ashley M Wellendorf, B.S., Breanna Bohan, James F Johnson, Yi Zheng, PhD, Jose A Cancelas, MD

Blood (2019) 134 (Supplement_1): 99.

https://doi.org/10.1182/blood-2019-125359

Published: 2019

Journal Articles

Ifitm3 Is Essential for PI(3,4,5)P3-Dependent B-Cell Activation and Leukemogenesis

Jaewoong Lee, PhD, Gang Xiao, PhD, Kadriye Nehir Nehir Cosgun, PhD, Huimin Geng, PhD, Ning Ma, PhD, Lai N Chan, PhD, Kohei Kume, PhD, Matthew Nix, PhD, Zhengshan Chen, MD PhD, Chun-Wei David Chen, PhD, Jianjun Chen, PhD, Vishal Khairnar, PhD, Arun P. Wiita, MD PhD, Andrei Thomas-Tikhonenko, PhD, Michael Farzan, MD PhD, Michael S. Diamond, PhD, Jae U Jung, PhD, Nagarajan Vaidehi, PhD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 2782.

https://doi.org/10.1182/blood-2019-127615

Published: 2019

Journal Articles

The Role of the Lipid Raft-Associated Protein Flotillin-2 during Development and Progression of Myeloid Leukaemia

Rahul Kumar, PhD, Raquel Pereira, M.Sc, Julian Niemann, Costanza Zanetti, MSc, Alex Azimpour, Melanie Meister, PhD, Parimala Sonika Godavarthy, MSc, Daniela S. Krause, MD

Blood (2019) 134 (Supplement_1): 2921.

https://doi.org/10.1182/blood-2019-122670

Published: 2019

Journal Articles

A New Role of Glutathion Peroxydase 4 in Human Erythroblast Enucleation

Hakim Ouled-Haddou, Kahia Messaoudi, Roggiero Lopes Dos Santos, Candice Carola, MD, Yohann Demont, Alexis Caulier, Pascal Vong, Nicolas Jankovsky, Delphine Lebon, MD, Jessica Platon, Julien Demagny, Nicolas Guillaume, Jean-Pierre Marolleau, MD PhD, Jacques Rochette, MB, DSc, Loïc Garçon

Blood (2019) 134 (Supplement_1): 938.

https://doi.org/10.1182/blood-2019-122161

Published: 2019

Journal Articles

A Unique Monocyte Transcriptome Discriminates Sickle Cell Disease from Other Hereditary Hemolytic Anemias and Shows the Particular Importance of Lipid and Interferon Signaling

Annelies J. Van Vuren, MD, Stephanie van Straaten, MD PhD, Michal Mokry, PhD, Richard van Wijk, PhD, Eduard J. van Beers, MD PhD

Blood (2019) 134 (Supplement_1): 980.

https://doi.org/10.1182/blood-2019-124070

Published: 2019

Journal Articles

Combined Treatment with Lenalidomide and Epoetin Alfa Leads to Durable Responses in Patients with Epo-Refractory, Lower Risk Non-Deletion 5q [Del(5q)] MDS: Final Results of the E2905 Intergroup Phase III Study - an ECOG-ACRIN Cancer Research Group Study, Grant CA180820, and the National Cancer Institute of the National Institutes of Health

Alan F. List, MD, Zhuoxin Sun, PhD, Amit Verma, MBBS, John M. Bennett, MD, Kathy McGraw, PhD, Jaroslaw P. Maciejewski, MD PhD, Rami S. Komrokji, MD, Timothy R. Wassenaar, MD, Selina M. Luger, MD FRCPC, Ryan J. Mattison, MD, Puneet S. Cheema, MD, Jessica K. Altman, David F. Claxton, MD, Charles A. Schiffer, MD, Andrew S. Artz, MD, Mark Litzow, MD, Martin S. Tallman, MD

Blood (2019) 134 (Supplement_1): 842.

https://doi.org/10.1182/blood-2019-127274

Published: 2019

Journal Articles

Phase 1, Open-Label, Dose Escalation Study of I-131-CLR1404 (CLR 131) in Patients with Relapsed or Refractory Multiple Myeloma

Jarrod Longcor, Kate Oliver, BS

Blood (2019) 134 (Supplement_1): 1864.

https://doi.org/10.1182/blood-2019-131806

Published: 2019

Journal Articles

Diffuse Large B-Cell Lymphoma Remodels the Fibroblastic Reticular Network That Acquires Aberrant Immunosuppressive Capabilities; Implications for the Regulation of Anti-Tumor Immunity in the Immuno-Oncology Era

Benedetta Apollonio, PhD, Peter Jarvis, MSc, Beth Phillips, MBBS, FRCPath, BSc, Andrea Kuhnl, Jon Salisbury, Georgios Zacharioudakis, Lesley-Ann Sutton, Richard Rosenquist, MD PhD, Ruth Jarrett, MBBChir, FRCPath, FRCP, Rose-Marie Amini, Anna Vardi, MD PhD, Alan G. Ramsay, BSc,MSc,PhD

Blood (2018) 132 (Supplement 1): 675.

https://doi.org/10.1182/blood-2018-99-116409

Published: 2018

Journal Articles

IFITM3-Mediated Regulation of Cell Membrane Dynamics Is Essential for Malignant B-Cell Transformation

Jae-Woong Lee, PhD, Huimin Geng, PhD, Derek S Dinson, Gang Xiao, PhD, Kadriye Nehir Cosgun, PhD, Lai N Chan, Zhengshan Chen, MDPhD, Michael Farzan, MDPhD, Jae U Jung, PhD, Arun P Wiita, MDPhD, Markus Muschen, MD

Blood (2018) 132 (Supplement 1): 552.

https://doi.org/10.1182/blood-2018-99-117472

Published: 2018

Journal Articles

Preclinical Evaluation of Safety and Biodistribution of Red Cell Microparticles (RMP): A Novel Hemostatic Agent

Ashish Rehni, PhD, Vibha Shukla, PhD, Hever Navarro-Quero, DVM, Carlos Bidot, Jr., Conner Haase, Anise Crane, Shivam Patel, Sebastian Koch, MD, Yeon S. Ahn, MD, Wenche Jy, PhD, Kunjan Dave, PhD

Blood (2018) 132 (Supplement 1): 1044.

https://doi.org/10.1182/blood-2018-99-116508

Published: 2018

Journal Articles

Altering Glycosphingolipid Composition to Improve Multiple Myeloma Bone Complication

Houfu Leng, MSc, DPhil, MBBS, BSc, Adel Ersek, PhD, Emma Morris, DPhil, Beatriz Gamez Molina, PhD, Claire M. Edwards, PhD, Nicole Horwood, PhD

Blood (2018) 132 (Supplement 1): 1942.

https://doi.org/10.1182/blood-2018-99-112237

Published: 2018

Journal Articles

New Antibcma-CAR for Multiple Myeloma

Lorena Perez Amill, PhD, Guillermo Suñe Rodriguez, PhD, Amer Najjar, PhD, Maria Castella Castella, PhD, Alvaro Urbano-Ispizua, MD, Beatriz Martin-Antonio, PhD

Blood (2017) 130 (Supplement 1): 2062.

https://doi.org/10.1182/blood.V130.Suppl_1.2062.2062

Published: 2017

Journal Articles

Upregulation of Alternatively Glycosylated Smoothened (SMO) Is Involved in Doxorubicin (DXR) Resistance in Diffuse Large B-Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, MS, Sandra Sanchez, MD, Amineh Vaghefi, MD, Darius Juskevicius, PhD, Alexandar Tzankov, Ramiro E Verdun, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD

Blood (2017) 130 (Supplement 1): 3839.

https://doi.org/10.1182/blood.V130.Suppl_1.3839.3839

Published: 2017

Journal Articles

A Critical Role for the IKKβ/Lipid Rafts Axis in Regulating Platelet Exocytosis, Via the Spatial Regulation of SNARE Proteins

Zubair A Karim, PhD, Nicole R Hensch, BS, MS, Hanan Qasim, BPharm, Fatima Z Alshbool, PharmD, PhD, Fadi T. Khasawneh, BPharm, PhD

Blood (2017) 130 (Supplement 1): 3602.

https://doi.org/10.1182/blood.V130.Suppl_1.3602.3602

Published: 2017

Journal Articles

Analysis of a Naturally Occurring PAR4 Variant By Hydrogen/Deuterium Exchange Reveals Its Structural Rearrangement upon Activation By Thrombin and the Molecular Basis for Altered Reactivity

Xu Han, BS, MS, Lukas Hofmann, PhD, Maria de la Fuente, BS, Tivadar Orban, PhD, Nathan Alexander, PhD, Krzysztof Palczewski, PhD, Marvin T Nieman, PhD

Blood (2017) 130 (Supplement 1): 453.

https://doi.org/10.1182/blood.V130.Suppl_1.453.453

Published: 2017

Journal Articles

Combined Treatment with Lenalidomide (LEN) and Epoetin Alfa (EA) Is Superior to Lenalidomide Alone in Patients with Erythropoietin (Epo)-Refractory, Lower Risk (LR) Non-Deletion 5q [Del(5q)] Myelodysplastic Syndrome (MDS): Results of the E2905 Intergroup Study-an ECOG-ACRIN Cancer Research Group Study, Grant CA180820, and the National Cancer Institute of the National Institutes of Health

Alan F List, MD, Zhuoxin Sun, PhD, Amit Verma, MD, John M. Bennett, MD, Kathy L McGraw, PhD, Lisa Ann Nardelli, BS, Jaroslaw P Maciejewski, MD PhD FACP, Jessica K Altman, MD, Puneet Cheema, MD, David F. Claxton, MD, Rami S. Komrokji, MD, Selina Luger, MD, Ryan Mattison, MD, Tim Wassenaar, MD, Andrew Artz, MD, Charles A Schiffer, MD, Martin S. Tallman, MD

Blood (2016) 128 (22): 223.

https://doi.org/10.1182/blood.V128.22.223.223

Published: 2016

Journal Articles

Functional Heterogeneity of Red Cell-Derived Microparticles from Different Sources: Calcium Ionophore V s . Storage V s . Extrusion

Sunjoo Cho, BS, Wenche Jy, PhD, Lawrence L Horstman, BS, Carlos Bidot Jr, BS, Miriam Yaniz, BS, Yeon S Ahn, MD

Blood (2016) 128 (22): 3770.

https://doi.org/10.1182/blood.V128.22.3770.3770

Published: 2016

Journal Articles

High Density Lipoprotein-like Nanoparticles Synergize with Akt and Btk Inhibitors to Induce Cell Death in Diffuse Large B Cell Lymphomas

Jonathan Scott Rink, PhD, Sol Misener, Osman Cen, PhD, Shuo Yang, Leo I. Gordon, MD, Colby Shad Thaxton, MD, PhD

Blood (2016) 128 (22): 3022.

https://doi.org/10.1182/blood.V128.22.3022.3022

Published: 2016

Journal Articles

IFITM3 Is a Central Regulator of Lipid Raft Signaling and Essential for CD19 Surface Expression and PI3K Signaling in Human B Cell Malignancies

Jae-Woong Lee, PhD, Huimin Geng, PhD, Kadriye Nehir Cosgun, PhD, Lai N Chan, PhD, Zhengshan Chen, MD PhD, Eugene Park, Lars Klemm, BSc, MSc, Charles C. Bailey, Markus Müschen, MD PhD

Blood (2016) 128 (22): 2738.

https://doi.org/10.1182/blood.V128.22.2738.2738

Published: 2016

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Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

Ifitm3 Is Essential for PI(3,4,5)P3-Dependent B-Cell Activation and Leukemogenesis

The Role of the Lipid Raft-Associated Protein Flotillin-2 during Development and Progression of Myeloid Leukaemia

A New Role of Glutathion Peroxydase 4 in Human Erythroblast Enucleation

A Unique Monocyte Transcriptome Discriminates Sickle Cell Disease from Other Hereditary Hemolytic Anemias and Shows the Particular Importance of Lipid and Interferon Signaling

Phase 1, Open-Label, Dose Escalation Study of I-131-CLR1404 (CLR 131) in Patients with Relapsed or Refractory Multiple Myeloma

Diffuse Large B-Cell Lymphoma Remodels the Fibroblastic Reticular Network That Acquires Aberrant Immunosuppressive Capabilities; Implications for the Regulation of Anti-Tumor Immunity in the Immuno-Oncology Era

IFITM3-Mediated Regulation of Cell Membrane Dynamics Is Essential for Malignant B-Cell Transformation

Preclinical Evaluation of Safety and Biodistribution of Red Cell Microparticles (RMP): A Novel Hemostatic Agent

Altering Glycosphingolipid Composition to Improve Multiple Myeloma Bone Complication

New Antibcma-CAR for Multiple Myeloma

Upregulation of Alternatively Glycosylated Smoothened (SMO) Is Involved in Doxorubicin (DXR) Resistance in Diffuse Large B-Cell Lymphoma

A Critical Role for the IKKβ/Lipid Rafts Axis in Regulating Platelet Exocytosis, Via the Spatial Regulation of SNARE Proteins

Analysis of a Naturally Occurring PAR4 Variant By Hydrogen/Deuterium Exchange Reveals Its Structural Rearrangement upon Activation By Thrombin and the Molecular Basis for Altered Reactivity

Functional Heterogeneity of Red Cell-Derived Microparticles from Different Sources: Calcium Ionophore V s . Storage V s . Extrusion

High Density Lipoprotein-like Nanoparticles Synergize with Akt and Btk Inhibitors to Induce Cell Death in Diffuse Large B Cell Lymphomas

IFITM3 Is a Central Regulator of Lipid Raft Signaling and Essential for CD19 Surface Expression and PI3K Signaling in Human B Cell Malignancies

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