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Journal Articles

Deletion of CISH in Human Pluripotent Stem Cell-Derived Natural Killer Cells Enhances Anti-Tumor Activity Via Metabolic Reprogramming

Huang Zhu, PhD, Robert Blum, Zhengming Wu, Zhipeng Meng, PhD, Kun-Liang Guan, PhD, Dan S Kaufman, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 619.
https://doi.org/10.1182/blood-2019-124446
Published: 2019
Journal Articles

Homozygosity for -2518 G Allele Variant of MCP-1 Predisposes to Adverse Presentation and Outcome in Primary Myelofibrosis

Elena Masselli, MD, Cecilia Carubbi, PhD, Giulia Pozzi, MS, Antonio Percesepe, MD PhD, Rita Campanelli, Laura Villani, Giuliana Gobbi, PhD, Vittorio Rosti, MD, Margherita Massa, Giovanni Barosi, Marco Vitale, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1689.
https://doi.org/10.1182/blood-2019-122750
Published: 2019
Journal Articles

Phase 1-2 Study of Pembrolizumab Combined with the Anti-LAG-3 Antibody MK-4280 for the Treatment of Hematologic Malignancies

Philippe Armand, Pier Luigi Luigi Zinzani, MD, John Palcza, Jane Anne Healy, Akash Nahar, Patricia Marinello, Gareth P Gregory, MBBS (Hons), PhD FRACP, FRCPA
Journal: Blood
Blood (2019) 134 (Supplement_1): 1548.
https://doi.org/10.1182/blood-2019-127474
Published: 2019
Journal Articles

HSCs Fated to Progress to Blast Phase Can be Detected in Myelofibrosis Patients Several Years Prior to Leukemic Transformation

Jenny M. Ho, MD, Jessie J.F. Medeiros, BSc, Michelle Chan-Seng-Yue, Lauren Hummel, BSc, Andrea Arruda, Amanda Mitchell, PhD, Caroline J McNamara, MBBS, James A Kennedy, MD PhD, Anne Tierens, MD PhD, Dawn Maze, MDFRCPC,MSc, Hubert Tsui, MD PhD, Mark D. Minden, MD PhD, Vikas Gupta, MD FRCP, FRCPath, John E. Dick, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1676.
https://doi.org/10.1182/blood-2019-130923
Published: 2019
Journal Articles

Elevated Plasma sIL-2Rα Levels in Primary Myelofibrosis Play a Distinct Role on Disease Progression in JAK2V617F and Calr Mutants

Giovanni Barosi, Rita Campanelli, Paolo Catarsi, Mara De Amici, Carlotta Abbà, MSc, Gianluca Viarengo, Laura Villani, Margherita Massa, Vittorio Rosti, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1678.
https://doi.org/10.1182/blood-2019-125531
Published: 2019
Journal Articles

Spatial Genomic Heterogeneity in Chronic Lymphocytic Leukemia

Clare Sun, MD, Yun-Ching Chen, PhD, Aina Zurita Martinez, Delong Liu, PhD, Daniel Rosebrock, Gad Getz, PhD, Mehdi Pirooznia, MD PhD, Catherine J. Wu, MD, Adrian Wiestner, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3017.
https://doi.org/10.1182/blood-2019-123441
Published: 2019
Journal Articles

Impact of Adding Melphalan to Fludarabine and a Myeloablative Dose of Intravenous Busulfan for Patients Who Received Allogeneic Hematopoietic Stem Cell Transplantation

Yoshimitsu Shimomura, Masahiko Hara, MD PhD, Hisashi Yamamoto, MD PhD, Tatsuo Ichinohe, Takahiro Fukuda, Minoko Takanashi, MD PhD, Yoshiko Atsuta, MD PhD, Takayuki Ishikawa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 254.
https://doi.org/10.1182/blood-2019-125470
Published: 2019
Journal Articles

Genomic Characterization of a Pediatric Cohort with Non-Malignant Lymphoproliferative Disorders

Olive S. Eckstein, MD, Nitya Gulati, MBBS, Lisa Forbes, MD, Erin Peckham-Gregory, PhD MPH, Nmazuo Wudo Ozuah, MBBS, M. Cecilia Poli, MD, PhD, Tiphanie Vogel, Emily M Mace, PhD, Jordan S Orange, MD PhD, Jason Caldwell, D.O., Stephen Jolles, Fracesco Saettini, Hey J Chong, Asbjørg Stray-Pedersen, Helen E. Heslop, MD DSc, Kala Kamdar, MD, Robert A. Krance, MD, Swati Naik, MBBS, Tami D John, MD, Rayne H. Rouce, MD, Donna Muzny, Shalini Jhangiani, Richard Gibbs, Zeynep Coban-Akdemir, James Lupski, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD, Ivan Chinn
Journal: Blood
Blood (2019) 134 (Supplement_1): 83.
https://doi.org/10.1182/blood-2019-131884
Published: 2019
Journal Articles

LAG3 Promotes Acute Myeloid Leukemia-Induced Immune Suppression

Haitham Abdelhakim, MD, Neil Dunavin, MD, Meizhang Li, PhD, Mitchell Braun, BS, Ahmed Elkhanany, MD, Tara L Lin, MD, Andrew K Godwin, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2414.
https://doi.org/10.1182/blood-2018-99-117784
Published: 2018
Journal Articles

Exploring LAG-3 Expression in Multiple Myeloma Patients Following Autologous Stem Cell Transplant

Lucas Fabienne, PhD, Michael Pennell, PhD, Don M. Benson, Jr., MD PhD, Yvonne Efebera, MD, Maria Chaudhry, MD, Jennifer A. Woyach, MD, Xiangnan Guan, Zhang Suohui, Christin E Burd, PhD, Ashley E. Rosko, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3434.
https://doi.org/10.1182/blood-2018-99-119577
Published: 2018
Journal Articles

Efficient Gene Transduction and Reprogramming of Hematopoietic Cells Including T-Cells By Using a Non-Integrating Measles Virus Vector

Jiyuan Liao, PhD, Yasushi Soda, MD PhD, Ai Sugawara, B.Sc., Yoshie Miura, PhD, Takafumi Hiramoto, PhD, Maino Tahara, PhD, Yuto Takishima, M.S., Lisa Hirose, Yasuki Hijikata, MD PhD, Shohei Miyamoto, PhD, Makoto Takeda, MD PhD, Kenzaburo Tani, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3494.
https://doi.org/10.1182/blood-2018-99-120350
Published: 2018
Journal Articles

Indoleamine 2,3-Dioxygenase-1 Expressing Dendritic Cell Populations Are Associated with Tumor-Induced Immune Tolerance & Aggressive Disease Biology in Chronic Myelomonocytic Leukemia

Abhishek A. Mangaonkar, MD, Kaaren K. Reichard, MD, April Chiu, MD, Matthew T Howard, MD, Rebecca L King, MD, Ryan M. Carr, MD, PhD, Bonnie M Alver, Keith D. Robertson, Margot Cousin, PhD, Jose C Villasboas, Martin E. Fernandez-Zapico, MD, Terra L. Lasho, PhD, Naseema Gangat, MBBS, Aref Al-Kali, MD, Michelle A. Elliott, MD, William J. Hogan, MBBCh, Mark R. Litzow, MD, Animesh Pardanani, MBBS, PhD, Eric Solary, MD PhD, Ayalew Tefferi, MD, Mrinal M. Patnaik, MD MBBS
Journal: Blood
Blood (2018) 132 (Supplement 1): 4344.
https://doi.org/10.1182/blood-2018-99-113881
Published: 2018
Journal Articles

CRISPR/Cas9-Mediated Disruption of PD-L1 Reduces the T Cell Suppressive Effect of Wharton's Jelly Mesenchymal Stromal Cells and Their Extracellular Vesicles

Neil Dunavin, MD, Meizhang Li, PhD, Safinur Atay, PhD, Jim Mitchell, Rupal Soder, PhD, Sunil Abhyankar, MD, Joseph P. McGuirk, DO, Andrew K Godwin, PhD, Buddhadeb Dawn, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5095.
https://doi.org/10.1182/blood-2018-99-116921
Published: 2018
Journal Articles

CD84: A Potential Novel Therapeutic Target in Multiple Myeloma

Emine Gulsen Gunes, PhD, Hadas Lewinsky, Domenico Viola, Enrico Caserta, Michael Rosenzweig, Myo Htut, James F Sanchez, PhD, Ralf Buettner, PhD, Guido Marcucci, Jonathan J Keats, PhD, Amrita Krishnan, MD, Steven T Rosen, Idit Shachar, Flavia Pichiorri, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1924.
https://doi.org/10.1182/blood-2018-99-119655
Published: 2018
Journal Articles

T Cell Metabolism and Memory

Jeffrey C Rathmell, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): SCI-6.
https://doi.org/10.1182/blood-2018-99-109535
Published: 2018
Journal Articles

Anthropometric Traits and Risk of Non-Hodgkin Lymphoma (NHL) and Major NHL Subtypes: A Pooled Prospective Analysis

Brenda M Birmann, ScD, Ke Wang, MPH, Kimberly A Bertrand, PhD, Chun R Chao, PhD, Emily L. Deubler, MPH, Sophia S. Wang, PhD, Lauren R Teras, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2972.
https://doi.org/10.1182/blood-2018-99-113572
Published: 2018
Journal Articles

Adaptive NK Cells Are Expanded By NKG2C-Agonist Antibodies and Retain Their Cytotoxic and Secretory Properties

Aimee Merino, MD PhD, Phillip Dougherty, BS, Bin Zhang, PhD, J.P. Houchins, PhD, Jeffrey S. Miller, MD, Frank Cichocki, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3695.
https://doi.org/10.1182/blood-2018-99-113669
Published: 2018
Journal Articles

Targeted Deep Sequencing in Blast Phase Myeloproliferative Neoplasms

Ayalew Tefferi, MD, Terra L. Lasho, PhD, Mythri Mudireddy, MBBS, Christy Finke, BS, Kebede H. Begna, MD, Curtis A. Hanson, MD, Rhett P. Ketterling, MD, Naseema Gangat, MBBS, Animesh Pardanani, MBBS PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4193.
https://doi.org/10.1182/blood.V130.Suppl_1.4193.4193
Published: 2017
Journal Articles

Evidence of Targetable Immune Dysfunction in the Bone Marrow of Patients with Intermediate/High-Risk Myelodysplastic Syndrome Refractory to Hypomethylating Agents

Cherie Green, Mark Yan, Stefani Nalle, Connie Ma, Alberto Robert, Judy Zhong, Kartik Krishnan, Patrick Phuong, PharmD, John Byon, Paul Woodard, Michael J. Nemeth, PhD, Elizabeth A. Griffiths, MD, Joanne I. Adamkewicz, Jeffrey M. Venstrom, Monique Dail
Journal: Blood
Blood (2017) 130 (Supplement 1): 4241.
https://doi.org/10.1182/blood.V130.Suppl_1.4241.4241
Published: 2017
Journal Articles

Lenalidomide-Mediated Erythroid Improvement in Non-Del(5q) Myelodysplastic Syndromes Is Associated with Bone Marrow Immuno-Remodeling

Gwenneg Kerdivel, PhD, Virginie Chesnais, PhD, Etienne Becht, PhD, Andrea Toma, MD PhD, Nicolas Cagnard, PhD, Florent Dumont, PhD, Alice Rousseau, Pierre Fenaux, MD PhD, Sylvie Chevret, MD PhD, Nicolas Chapuis, PharmD, PhD, Valentina Boeva, PhD, Wolf-Herman Fridman, Olivier Kosmider, Michaela Fontenay, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2983.
https://doi.org/10.1182/blood.V130.Suppl_1.2983.2983
Published: 2017