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Journal Articles

Oncogenic Mechanisms of CBL E3 Ubiquitin Ligase Mutations in Myeloid Malignancies

Roger Belizaire, MD PhD, Sebastian Koochaki, BS, MS, Namrata Udeshi, PhD, Alexis Vedder, BS, Lei Sun, Monica Schenone, PhD, Steven Carr, PhD, Eric Padron, MD, Benjamin L. Ebert, MD PhD

Blood (2019) 134 (Supplement_1): 563.

https://doi.org/10.1182/blood-2019-122503

Published: 2019

Journal Articles

Improved Anti-Leukemic Pre-Clinical Efficacy of a Protac Based MDM2 Degrader in a Large AML Cohort

Malathi Kandarpa, PhD, Luke F. Peterson, PhD, Harish Potu, PhD, Megha Ramappan, Yihong Liu, Avery Polk, Shaomeng Wang, PhD, Moshe Talpaz, MD

Blood (2019) 134 (Supplement_1): 2670.

https://doi.org/10.1182/blood-2019-131949

Published: 2019

Journal Articles

Can Monosomy 7 be Targeted By Next Generation Cereblon-Modulating Agents?

Blood (2019) 134 (Supplement_1): 1270.

https://doi.org/10.1182/blood-2019-128967

Published: 2019

Journal Articles

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

Shuhei Asada, MD PhD, Susumu Goyama, MD PhD, Reina Takeda, MD, Keita Yamamoto, MD, Hiroko Kozuka-Hata, PhD, Masaaki Oyama, PhD, Daichi Inoue, MD PhD, Hiroaki Honda, MD PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 731.

https://doi.org/10.1182/blood-2019-125959

Published: 2019

Journal Articles

Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells

Harold K. Elias, MD, Christina Spevak, PhD, Lavanya Kannan, PhD, Mohamed A.E. Ali, MD PhD, Gaelle H Martin, PhD, Shanmugapriya Selvaraj, MS, William S Eng, Guangjie Zhao, BS, Amanda Ernlund, PhD, Vinagolu Rajasekhar, PhD, Carolien M Woolthuis, MD PhD, Robert J Schneider, PhD, Christopher Y. Park, MD PhD

Blood (2019) 134 (Supplement_1): 1180.

https://doi.org/10.1182/blood-2019-131333

Published: 2019

Journal Articles

Suppression of CUL4B Induces G1 Cell Cycle Arrest through the Modulation of AKT Signaling Pathway

Ying Li, MD, Ya Zhang, MD, Xiangxiang Zhou, MD, Xin Wang, MDPhD

Blood (2018) 132 (Supplement 1): 5133.

https://doi.org/10.1182/blood-2018-99-118442

Published: 2018

Journal Articles

FBXO11 Activates Erythroid Gene Transcription By Degrading Heterochromatin-Associated Protein BAHD1

Peng Xu, PhD, Daniel C. Scott, PhD, Xing Tang, PhD, Yu Yao, MD, Yong-Dong Wang, PhD, Wenjian Bi, PhD, Lance E. Palmer, PhD, Ruopeng Feng, PhD, Arno F. Alpi, PhD, Chunliang Li, PhD, Yong Cheng, PhD, Brenda A. Schulman, PhD, Mitchell J. Weiss, MD PhD

Blood (2018) 132 (Supplement 1): 529.

https://doi.org/10.1182/blood-2018-99-117362

Published: 2018

Journal Articles

Domain-Focused CRISPR-Cas9 Screen Identifies the E3 Ubiquitin Ligase Substrate Adaptor Protein SPOP as a Novel Repressor of Fetal Hemoglobin

Xianjiang Lan, PhD, Eugene Khandros, MD PhD, Jeremy D. Grevet, BA, Scott A. Peslak, MD, Saurabh Bhardwaj, PhD, Cheryl A. Keller, PhD, Belinda Giardine, Ben A. Garcia, PhD, Ross C. Hardison, PhD, Junwei Shi, PhD, Gerd A. Blobel, MD PhD

Blood (2018) 132 (Supplement 1): 414.

https://doi.org/10.1182/blood-2018-99-119518

Published: 2018

Journal Articles

Mitochondria Clearance Mechanisms Via Interaction with Macrophages in Erythropoiesis

Chong Yang, PhD, Toshio Suda, MD PhD, Xiaoxuan Lin, Mitsuhiro Endo, PhD

Blood (2018) 132 (Supplement 1): 2320.

https://doi.org/10.1182/blood-2018-99-110049

Published: 2018

Journal Articles

Cereblon and Redox in Plasma Cells

Florian Bassermann, MD PhD

Blood (2017) 130 (Supplement 1): SCI-9.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-9.SCI-9

Published: 2017

Journal Articles

IKZF1/3 and CRL4 CRBN E3 Ubiquitin Ligase Mutations Associate with IMiD Resistance in Relapsed Multiple Myeloma

Santiago Barrio Garcia, PhD, Matteo Da Via', MD, Andoni Garitano-Trojaola, PhD, Yanira Ruiz-Heredia, Max Bittrich, MD, ChangXin Shi, PhD, Yuan Zhu, Nicola Lehners, MD, Elias K Mai, MD, Marc S Raab, MD PhD, Pieter Sonneveld, MDPhD, Joaquín Martínez, Andreas Rosenwald, Esteban Braggio, PhD, Hermann Einsele, A. Keith Stewart, MBChB, MBA, K. Martin Kortüm, MD

Blood (2017) 130 (Supplement 1): 270.

https://doi.org/10.1182/blood.V130.Suppl_1.270.270

Published: 2017

Journal Articles

USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status

Blood (2017) 130 (2): 156–166.

https://doi.org/10.1182/blood-2016-12-758219

Published: 2017

Includes: Supplemental data

Journal Articles

GATA Factor Switching during Erythroid Differentiation Is Facilitated By FBW7 Mediated Clearance of GATA2

Alireza Ghamari, Gabriela Pregerning, Ernest Fraenkel, Alan B. Cantor

Blood (2016) 128 (22): 1479.

https://doi.org/10.1182/blood.V128.22.1479.1479

Published: 2016

Journal Articles

The E3 Ubiquitin Ligase HUWE1 Is a Potential Therapeutic Target for Multiple Myeloma

Lisa Crawford, BSc, PhD, Alexandra E Irvine, PhD FRCPath

Blood (2016) 128 (22): 240.

https://doi.org/10.1182/blood.V128.22.240.240

Published: 2016

Journal Articles

TRAF6 Is Essential for Maintaining Hematopoietic Stem Cell Homeostasis

Jing Fang, MD PhD, Lyndsey Bolanos, BSc, Juana Serrano-Lopez, PhD, Susanne Christie, Jose A Cancelas, MD PhD, Daniel T Starczynowski, PhD

Blood (2016) 128 (22): 568.

https://doi.org/10.1182/blood.V128.22.568.568

Published: 2016

Journal Articles

Cereblon Deficiency Leads to Alteration in c-Myc Regulated Genes, Increased Glucose Uptake and Resistance to JQ1 Bromodomain Inhibition

Matthew S Beatty, PhD, Rebecca S Hesterberg, BA, Ying Han, MD, Eric Padron, MD, Adam W Mailloux, PhD, Sean Yoder, M.S, Anjali M Rajadhyaksha, PhD, Alan F. List, MD, Pearlie K Epling-Burnette, PhD

Blood (2015) 126 (23): 286.

https://doi.org/10.1182/blood.V126.23.286.286

Published: 2015

Journal Articles

Identification of a Cereblon-Independent Protein Degradation Pathway in Residual Myeloma Cells Treated with Immunomodulatory Drugs

Rakesh Verma, PhD, Zifeng Mai, MS, Mina Xu, MD, Lin Zhang, Kavita Dhodapkar, MBBS, Madhav V Dhodapkar, MD

Blood (2015) 126 (23): 913.

https://doi.org/10.1182/blood.V126.23.913.913

Published: 2015

Journal Articles

The E3 Ubiquitin Ligase Cbl-b Limits Nascent Th9 Differentiation

Isabelle Cornez, Sowmya Parampalli Yajnanarayana, Natascha Hermann-Kleiter, Stefan Ulrich Schmidt, Peter Brossart, MD, Natalio Garbi, Gottfried Baier, Dominik Wolf, MD

Blood (2015) 126 (23): 2222.

https://doi.org/10.1182/blood.V126.23.2222.2222

Published: 2015

Journal Articles

Platelet FcγRIIA Signaling Results in Ubiquitination and Cellular Translocation of Activated Syk

Shaji Abraham, PhD, Leonard C. Edelstein, PhD, Chad A Shaw, PhD, Pierrette Andre, MS, Xianguo Kong, MD, Carol T Dangelmaier, Alexander Tsygankov, PhD, Paul F Bray, MD, Satya P. Kunapuli, PhD, Steven E. McKenzie, MD PhD

Blood (2014) 124 (21): 2761.

https://doi.org/10.1182/blood.V124.21.2761.2761

Published: 2014

Journal Articles

Somatic Mutations in E3 Ubiquitin Ligase Deltex 1 Are Associated with Survival in Diffuse Large B-Cell Lymphoma

Minna Taskinen, PhD, Leo Meriranta, BM, Annika Pasanen, MD PhD, Riku Louhimo, MSc, Alejandra Cervera, MSc, Marja-Liisa Karjalainen-Lindsberg, MD PhD, Harald Holte, MD PhD, Jan Delabie, MD PhD, Rainer Lehtonen, PhD, Sampsa Hautaniemi, PhD, Sirpa Leppä

Blood (2014) 124 (21): 1688.

https://doi.org/10.1182/blood.V124.21.1688.1688

Published: 2014

NARROW

Oncogenic Mechanisms of CBL E3 Ubiquitin Ligase Mutations in Myeloid Malignancies

Improved Anti-Leukemic Pre-Clinical Efficacy of a Protac Based MDM2 Degrader in a Large AML Cohort

Can Monosomy 7 be Targeted By Next Generation Cereblon-Modulating Agents?

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells

Suppression of CUL4B Induces G1 Cell Cycle Arrest through the Modulation of AKT Signaling Pathway

FBXO11 Activates Erythroid Gene Transcription By Degrading Heterochromatin-Associated Protein BAHD1

Domain-Focused CRISPR-Cas9 Screen Identifies the E3 Ubiquitin Ligase Substrate Adaptor Protein SPOP as a Novel Repressor of Fetal Hemoglobin

Mitochondria Clearance Mechanisms Via Interaction with Macrophages in Erythropoiesis

Cereblon and Redox in Plasma Cells

IKZF1/3 and CRL4 CRBN E3 Ubiquitin Ligase Mutations Associate with IMiD Resistance in Relapsed Multiple Myeloma

USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status

GATA Factor Switching during Erythroid Differentiation Is Facilitated By FBW7 Mediated Clearance of GATA2

The E3 Ubiquitin Ligase HUWE1 Is a Potential Therapeutic Target for Multiple Myeloma

TRAF6 Is Essential for Maintaining Hematopoietic Stem Cell Homeostasis

Cereblon Deficiency Leads to Alteration in c-Myc Regulated Genes, Increased Glucose Uptake and Resistance to JQ1 Bromodomain Inhibition

Identification of a Cereblon-Independent Protein Degradation Pathway in Residual Myeloma Cells Treated with Immunomodulatory Drugs

The E3 Ubiquitin Ligase Cbl-b Limits Nascent Th9 Differentiation

Platelet FcγRIIA Signaling Results in Ubiquitination and Cellular Translocation of Activated Syk

Somatic Mutations in E3 Ubiquitin Ligase Deltex 1 Are Associated with Survival in Diffuse Large B-Cell Lymphoma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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